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Dosage ranges in the studies above varied quite a bit. Solid anti-inflammatory effects are seen at doses as low as 20 mg/kg body weight in animal research, while a dosage of around 80 mg/kg of bodyweight yielded the blood glucose-regulating, lipid-lowering, radical-scavenging effects we’ve touched on. For reference, this range nets us roughly 200-800 mg/day dosing for a 150-200 lb individual, but this depends on the weight of the animals in the studies, which weren’t disclosed.
All in all, we believe that a 200 mg dose taken twice per day will yield the best results in terms of benefits and cost-effectiveness. 4-HC can be taken on an empty stomach, and is best used prior to a meal if looking to achieve blood sugar lowering effects. This is also in line with other curcumin supplements, which often require twice the above dose for best results. *