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There are no guidelines directing the appropriate use of papain supplements or ointments. Most papain supplements are available in capsules form but are also sold as tablets, chewable tablets, gummies, and powders.
Dosages between 25 and 100 mg per day are generally considered safe and well-tolerated. Avoid dosages larger than 400 mg per day. To reduce the risk of side effects, take the supplement in divided doses with meals.
Papain ointments can be applied lightly to the skin. Stop and call your doctor if the ointment causes any redness, inflammation, rash, or pain. *