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There is currently insufficient evidence to recommend an ideal dose of arachidonic acid supplementation, but anecdotally it is used at the dosage of around 2,000 mg taken 45 minutes before a workout. It is uncertain if this is an optimal dose or whether the timing is required.
It should also be noted that for persons with chronic inflammatory disorders, such as rheumatoid arthritis or inflammatory bowel diseases, that the ideal dose of arachidonic acid may actually be a dietary restriction thereof. In instances of inflammatory diseases, arachidonic acid supplementation is likely contraindicated. *
Based on the above studies and the scientific benefits, arachidonic acid supplements are best utilized when you consume 1.5g per day. This translates to 1500 mg of arachidonic acid every day, although you can certainly take less depending on the other supplements and how well you tolerate it. It’s a good idea to start off with 250 mg to 500 mg of arachidonic acid if you haven’t already tried the supplement before and aren’t sure about potential side effects.
As described above, some side effects have been noted, particularly in those who already have inflammatory conditions. If you do start to experience some side effects, slowly taper off your consumption of arachidonic acid and see if things get better. *