| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Metformin | Age-Related Macular Degeneration | 11 | PM | 38408173 | 📋 | Association of metformin use with risk of newly onset neovascular age-related macular degeneration development |
| Metformin | Age-Related Macular Degeneration | 10 | PM | 38259182 | 📋 | ASSOCIATION OF METFORMIN USE WITH RISK OF NEWLY ONSET NEOVASCULAR AGE-RELATED MACULAR DEGENERATION DEVELOPMENT |
| Metformin | Age-Related Macular Degeneration | 9 | PM | 38108689 | 📋 | Oral Metformin Inhibits Choroidal Neovascularization by Modulating the Gut-Retina Axis |
| Metformin | Age-Related Macular Degeneration | 8 | PM | 38074151 | 📋 | Dose-response association of metformin use and risk of age-related macular degeneration among patients with type 2 diabetes mellitus: a population-based study |
| Metformin | Age-Related Macular Degeneration | 7 | PM | 38059999 | 📋 | Metformin protects retinal pigment epithelium cells against H2O2-induced oxidative stress and inflammation via the Nrf2 signaling cascade |
| Metformin | Age-Related Macular Degeneration | 6 | PM | 38019527 | 📋 | Metformin Use and Age-Related Macular Degeneration in Patients Without Diabetes |
| Metformin | Age-Related Macular Degeneration | 5 | PM | 37589984 | 📋 | Association of Metformin and Other Diabetes Medication Use and the Development of New-Onset Dry Age-Related Macular Degeneration: A Case-Control Study |
| Metformin | Age-Related Macular Degeneration | 4 | PM | 37259372 | 📋 | The Risk of Age-Related Macular Degeneration Is Reduced in Type 2 Diabetes Patients Who Use Metformin |
| Metformin | Age-Related Macular Degeneration | 3 | PM | 36484633 | 📋 | Association Between Oral Metformin Use and the Development of Age-Related Macular Degeneration in Diabetic Patients: A Systematic Review and Meta-Analysis |
| Metformin | Age-Related Macular Degeneration | 2 | PM | 35972434 | 📋 | Using Advanced Bioinformatics Tools to Identify Novel Therapeutic Candidates for Age-Related Macular Degeneration |
| Metformin | Age-Related Macular Degeneration | 1 | PM | 35196199 | 📋 | Treatments targeting autophagy ameliorate the age-related macular degeneration phenotype in mice lacking APOE (apolipoprotein E) |
| Metformin | Diabetic Cataract | 1 | PM | 37644328 | 📋 | Metformin protects human lens epithelial cells from high glucose-induced senescence and autophagy inhibition by upregulating SIRT1 |
| Metformin | Diabetic Retinopathy | 5 | PM | 37348156 | 📋 | Metformin inhibits methylglyoxal-induced retinal pigment epithelial cell death and retinopathy via AMPK-dependent mechanisms: Reversing mitochondrial dysfunction and upregulating glyoxalase 1 |
| Metformin | Diabetic Retinopathy | 3 | PM | 36281139 | 📋 | Metformin therapy as a strategy to compensate anti-VEGF resistance in patients with diabetic macular edema |
| Metformin | Diabetic Retinopathy | 2 | PM | 35802672 | 📋 | Metformin suppresses pro-inflammatory cytokines in vitreous of diabetes patients and human retinal vascular endothelium |
| Metformin | Diabetic Retinopathy | 4 | PM | 33047165 | 📋 | Metformin attenuated histopathological ocular deteriorations in a streptozotocin-induced hyperglycemic rat model |
| Metformin | Diabetic Retinopathy | 1 | PM | 30017190 | 📋 | Alpha-lipoic Acid Reduces Retinal Cell Death in Diabetic Mice |
| Metformin | Dry Eye Syndrome | 1 | PM | 36151313 | 📋 | Incidence of metformin use in patients with age-related macular degeneration versus normal controls: A population-based study in Olmsted County, Minnesota |
| Metformin | Glaucoma | 2 | PM | 36598818 | 📋 | Metformin protects trabecular meshwork against oxidative injury via activating integrin/ROCK signals |
| Metformin | Glaucoma | 1 | PM | 35587864 | 📋 | Association of Diabetes Medication With Open-Angle Glaucoma, Age-Related Macular Degeneration, and Cataract in the Rotterdam Study |
| Metformin | Ocular Disorders | 1 | PM | 38251680 | 📋 | The Anti-Diabetic Drug Metformin Suppresses Pathological Retinal Angiogenesis via Blocking the mTORC1 Signaling Pathway in Mice (Metformin Suppresses Pathological Angiogenesis) |
| Metformin | Retinal Disorders | 1 | PM | 37869644 | 📋 | Metformin regulates the LIN28B‑mediated JNK/STAT3 signaling pathway through miR‑140‑3p in subretinal fibrosis |
| Metformin | Retinal Ischemia-Reperfusion | 1 | PM | 37253410 | 📋 | Metformin protects against retinal ischemia/reperfusion injury through AMPK-mediated mitochondrial fusion |
| Metformin | Wet Macular Degeneration | 1 | PM | 35972434 | 📋 | Using Advanced Bioinformatics Tools to Identify Novel Therapeutic Candidates for Age-Related Macular Degeneration |
