| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Paeoniflorin | Acute Kidney Injury | 1 | PM | 36753983 | 📋 | Paeoniflorin alleviates ischemia/reperfusion induced acute kidney injury by inhibiting Slc7a11-mediated ferroptosis |
| Paeoniflorin | Chronic Renal Failure | 2 | PM | 37247587 | 📋 | Paeoniflorin suppresses kidney inflammation by regulating macrophage polarization via KLF4-mediated mitophagy |
| Paeoniflorin | Chronic Renal Failure | 1 | PM | 35370668 | 📋 | Paeoniflorin Ameliorates Skeletal Muscle Atrophy in Chronic Kidney Disease via AMPK/SIRT1/PGC-1α-Mediated Oxidative Stress and Mitochondrial Dysfunction |
| Paeoniflorin | Diabetic Nephropathy | 3 | PM | 37733659 | 📋 | Protective effect of paeoniflorin in diabetic nephropathy: A preclinical systematic review revealing the mechanism of action |
| Paeoniflorin | Diabetic Nephropathy | 2 | PM | 36147345 | 📋 | Paeoniflorin directly binds to TNFR1 to regulate podocyte necroptosis in diabetic kidney disease |
| Paeoniflorin | Diabetic Nephropathy | 1 | PM | 36049428 | 📋 | Paeoniflorin binds to VEGFR2 to restore autophagy and inhibit apoptosis for podocyte protection in diabetic kidney disease through PI3K-AKT signaling pathway |
| Paeoniflorin | Nephrotoxicity | 1 | PM | 36972781 | 📋 | Paeoniflorin protects against cisplatin-induced acute kidney injury through targeting Hsp90AA1-Akt protein-protein interaction |
| Paeoniflorin | Renal Ischemia-Reperfusion | 1 | PM | 37884904 | 📋 | Paeoniflorin alleviates hypoxia/reoxygenation injury in HK-2 cells by inhibiting apoptosis and repressing oxidative damage via Keap1/Nrf2/HO-1 pathway |
