| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Apigenin | Bladder Cancer | 3 | PM | 29945448 | 📋 | Apigenin Suppresses the IL-1β-Induced Expression of the Urokinase-Type Plasminogen Activator Receptor by Inhibiting MAPK-Mediated AP-1 and NF-κB Signaling in Human Bladder Cancer T24 Cells |
| Apigenin | Bladder Cancer | 1 | PM | 25859163 | 📋 | Apigenin, a Dietary Flavonoid, Inhibits Proliferation of Human Bladder Cancer T-24 Cells via Blocking Cell Cycle Progression and Inducing Apoptosis |
| Apigenin | Bladder Cancer | 4 | PM | 23724790 | 📋 | Apigenin promotes apoptosis, inhibits invasion and induces cell cycle arrest of T24 human bladder cancer cells |
| Apigenin | Bladder Cancer | 2 | PM | 22423483 | 📋 | Apigenin Inhibits Cell Migration Through MAPK Pathways in Human Bladder Smooth Muscle Cells |
| Apigenin | Diabetic Nephropathy | 5 | PM | 38282447 | 📋 | The Effects of Apigenin in the Treatment of Diabetic Nephropathy: A Systematic Review of Non-clinical Studies |
| Apigenin | Diabetic Nephropathy | 3 | PM | 34017372 | 📋 | Protective mechanism of apigenin in diabetic nephropathy is related to its regulation of miR-423-5P-USF2 axis |
| Apigenin | Diabetic Nephropathy | 2 | PM | 32507768 | 📋 | CD38 Inhibition by Apigenin Ameliorates Mitochondrial Oxidative Stress Through Restoration of the Intracellular NAD +/NADH Ratio and Sirt3 Activity in Renal Tubular Cells in Diabetic Rats |
| Apigenin | Diabetic Nephropathy | 1 | PM | 31309931 | 📋 | Apigenin Protects Against Renal Tubular Epithelial Cell Injury and Oxidative Stress by High Glucose via Regulation of NF-E2-Related Factor 2 (Nrf2) Pathway |
| Apigenin | Diabetic Nephropathy | 4 | PM | 28566504 | 📋 | Apigenin ameliorates streptozotocin-induced diabetic nephropathy in rats via MAPK-NF-κB-TNF-α and TGF-β1-MAPK-fibronectin pathways |
| Apigenin | Interstitial Cystitis | 1 | PM | 37375759 | 📋 | Spasmolytic and Uroprotective Effects of Apigenin by Downregulation of TGF-β and iNOS Pathways and Upregulation of Antioxidant Mechanisms: In Vitro and In Silico Analysis |
| Apigenin | Kidney Damage | 1 | PM | 36808364 | 📋 | Apigenin ameliorates hypercholesterolemic-induced kidney injury via modulating renal KIM-1, Fn1, and Nrf2 signaling pathways |
| Apigenin | Kidney Disease | 1 | PM | 29966983 | 📋 | Apigenin Suppresses Mouse Peritoneal Fibrosis by Down-Regulating miR34a Expression |
| Apigenin | Kidney Fibrosis | 1 | PM | 32196447 | 📋 | Apigenin Alleviates Renal Fibroblast Activation Through AMPK and ERK Signaling Pathways in Vitro |
| Apigenin | Kidney Stones | 2 | PM | 34043992 | 📋 | Protective effect of apigenin on ethylene glycol-induced urolithiasis via attenuating oxidative stress and inflammatory parameters in adult male Wistar rats |
| Apigenin | Kidney Stones | 1 | PM | 32148363 | 📋 | Anticalculi Activity of Apigenin and Celery ( Apium graveolens L.) Extract in Rats Induced by Ethylene Glycol-Ammonium Chloride |
| Apigenin | Nephrotoxicity | 12 | PM | 38718656 | 📋 | Boswellic acid and apigenin alleviate methotrexate-provoked renal and hippocampal alterations in rats: Targeting autophagy, NOD-2/NF-κB/NLRP3, and connexin-43 |
| Apigenin | Nephrotoxicity | 11 | PM | 35613639 | 📋 | Apigenin alleviates cancer drug Sorafenib induced multiple toxic effects in Swiss albino mice via anti-oxidative stress |
| Apigenin | Nephrotoxicity | 10 | PM | 35484458 | 📋 | Apigenin attenuates molecular, biochemical, and histopathological changes associated with renal impairments induced by gentamicin exposure in rats |
| Apigenin | Nephrotoxicity | 9 | PM | 35227143 | 📋 | Apigenin and kaempferol as novel renoprotective agent against cisplatin-induced toxicity: an in vitro study |
| Apigenin | Nephrotoxicity | 4 | PM | 34043992 | 📋 | Protective effect of apigenin on ethylene glycol-induced urolithiasis via attenuating oxidative stress and inflammatory parameters in adult male Wistar rats |
| Apigenin | Nephrotoxicity | 1 | PM | 33845614 | 📋 | Apigenin alleviates methotrexate-induced liver and kidney injury in mice |
| Apigenin | Nephrotoxicity | 5 | PM | 33724625 | 📋 | Apigenin ameliorates oxidative stress and mitochondrial damage induced by multiwall carbon nanotubes in rat kidney mitochondria |
| Apigenin | Nephrotoxicity | 6 | PM | 33556877 | 📋 | Apigenin ameliorates doxorubicin-induced renal injury via inhibition of oxidative stress and inflammation |
| Apigenin | Nephrotoxicity | 3 | PM | 33515148 | 📋 | The potential protective role of apigenin against oxidative damage induced by nickel oxide nanoparticles in liver and kidney of male Wistar rat, Rattus norvegicus |
| Apigenin | Nephrotoxicity | 7 | PM | 32468621 | 📋 | Targeting Renal OATs to Develop Renal Protective Agent From Traditional Chinese Medicines: Protective Effect of Apigenin Against Imipenem-induced Nephrotoxicity |
| Apigenin | Nephrotoxicity | 8 | PM | 30107153 | 📋 | Protective Effects of Apigenin Against 3-MCPD-induced Renal Injury in Rat |
| Apigenin | Nephrotoxicity | 2 | PM | 28064632 | 📋 | Protective Effects of Apigenin and Myricetin Against Cisplatin-Induced Nephrotoxicity in Mice |
| Apigenin | Renal Cell Carcinoma | 2 | PM | 35088891 | 📋 | Apigenin inhibits renal cell carcinoma cell proliferation through G2/M phase cell cycle arrest |
| Apigenin | Renal Cell Carcinoma | 1 | PM | 28423637 | 📋 | Apigenin Inhibits Renal Cell Carcinoma Cell Proliferation |
| Apigenin | Renal Ischemia-Reperfusion | 2 | PM | 30278824 | 📋 | Effect of Apigenin on Apoptosis Induced by Renal Ischemia/Reperfusion Injury in Vivo and in Vitro |
| Apigenin | Renal Ischemia-Reperfusion | 1 | PM | 29285062 | 📋 | Effects of Apigenin on the Expression Levels of B-cell lymphoma-2, Fas and Fas Ligand in Renal Ischemia-Reperfusion Injury in Rats |
| Apigenin | Renal Ischemia-Reperfusion | 3 | PM | 28962085 | 📋 | Effects of apigenin pretreatment against renal ischemia/reperfusion injury via activation of the JAK2/STAT3 pathway |
| Apigenin | Renovascular Hypertension | 1 | PM | 26987380 | 📋 | Apigenin Ameliorates Hypertension-Induced Cardiac Hypertrophy and Down-Regulates Cardiac Hypoxia Inducible Factor-Lα in Rats |
