Substance | Condition | Seq | Src | PMID | Dtl | Title |
TUDCA | Acetaminophen Toxicity | 1 | PM | 27706903 | 📋 | Combination of tauroursodeoxycholic acid and N-acetylcysteine exceeds standard treatment for acetaminophen intoxication |
TUDCA | Alcohol Toxicity | 1 | PM | 33516881 | 📋 | Sirtuin 6 ameliorates alcohol-induced liver injury by reducing endoplasmic reticulum stress in mice |
TUDCA | Alcohol Toxicity | 3 | PM | 25538147 | 📋 | Reversal of glucose intolerance in rat offspring exposed to ethanol before birth through reduction of nuclear skeletal muscle HDAC expression by the bile acid TUDCA |
TUDCA | Alcohol Toxicity | 2 | PM | 23544086 | 📋 | Prenatal ethanol exposure causes glucose intolerance with increased hepatic gluconeogenesis and histone deacetylases in adult rat offspring: reversal by tauroursodeoxycholic acid |
TUDCA | Antibiotic Toxicity | 1 | PM | 29751043 | 📋 | Tauroursodeoxycholic acid attenuates gentamicin-induced cochlear hair cell death in vitro |
TUDCA | Cadmium Toxicity | 1 | PM | 30696534 | 📋 | Induction of Endoplasmic Reticulum Stress by Cadmium and Its Regulation on Nrf2 Signaling Pathway in Kidneys of Rats |
TUDCA | Cisplatin Toxicity | 1 | PM | 33631298 | 📋 | Tauroursodeoxycholic acid attenuates cisplatin-induced ototoxicity by inhibiting the accumulation and aggregation of unfolded or misfolded proteins in the endoplasmic reticulum |
TUDCA | Cisplatin Toxicity | 2 | PM | 32061715 | 📋 | Tauroursodeoxycholic acid attenuates cisplatin-induced hearing loss in rats |
TUDCA | Cisplatin Toxicity | 3 | PM | 29049998 | 📋 | Endoplasmic Reticulum Stress Is Involved in Cochlear Cell Apoptosis in a Cisplatin-Induced Ototoxicity Rat Model |
TUDCA | Environmental Pollutants Toxicity | 1 | PM | 27853103 | 📋 | Endoplasmic reticulum stress is involved in 2,4-dichlorophenol-induced hepatotoxicity |
TUDCA | Food and Additives Toxicity | 1 | PM | 30765332 | 📋 | The Food Additive Maltodextrin Promotes Endoplasmic Reticulum Stress-Driven Mucus Depletion and Exacerbates Intestinal Inflammation |
TUDCA | Genotoxicity | 1 | PM | 31793725 | 📋 | Tauroursodeoxycholic acid acts via TGR5 receptor to facilitate DNA damage repair and improve early porcine embryo development |
TUDCA | Hepatotoxicity | 5 | PM | 31963346 | 📋 | Activation of the IRE1α Arm, but not the PERK Arm, of the Unfolded Protein Response Contributes to Fumonisin B1-Induced Hepatotoxicity |
TUDCA | Hepatotoxicity | 3 | PM | 31484321 | 📋 | Polyhexamethyleneguanidine Phosphate-Induced Cytotoxicity in Liver Cells Is Alleviated by Tauroursodeoxycholic Acid (TUDCA) via a Reduction in Endoplasmic Reticulum Stress |
TUDCA | Hepatotoxicity | 4 | PM | 29187671 | 📋 | Bavachin Induces Apoptosis through Mitochondrial Regulated ER Stress Pathway in HepG2 Cells |
TUDCA | Hepatotoxicity | 2 | PM | 28688954 | 📋 | Rifampicin-induced injury in HepG2 cells is alleviated by TUDCA via increasing bile acid transporters expression and enhancing the Nrf2-mediated adaptive response |
TUDCA | Hepatotoxicity | 1 | PM | 27853103 | 📋 | Endoplasmic reticulum stress is involved in 2,4-dichlorophenol-induced hepatotoxicity |
TUDCA | Herbicide Toxicity | 2 | PM | 33082501 | 📋 | Endoplasmic reticulum stress-related neuroinflammation and neural stem cells decrease in mice exposure to paraquat |
TUDCA | Herbicide Toxicity | 1 | PM | 23416354 | 📋 | Sodium tauroursodeoxycholate prevents paraquat-induced cell death by suppressing endoplasmic reticulum stress responses in human lung epithelial A549 cells |
TUDCA | Nephrotoxicity | 1 | PM | 30696534 | 📋 | Induction of Endoplasmic Reticulum Stress by Cadmium and Its Regulation on Nrf2 Signaling Pathway in Kidneys of Rats |
TUDCA | Neurotoxicity | 2 | PM | 33082501 | 📋 | Endoplasmic reticulum stress-related neuroinflammation and neural stem cells decrease in mice exposure to paraquat |
TUDCA | Neurotoxicity | 1 | PM | 30116207 | 📋 | Cognitive Impairment and Endoplasmic Reticulum Stress Induced by Repeated Short-Term Sevoflurane Exposure in Early Life of Rats |
TUDCA | Ototoxicity | 1 | PM | 33631298 | 📋 | Tauroursodeoxycholic acid attenuates cisplatin-induced ototoxicity by inhibiting the accumulation and aggregation of unfolded or misfolded proteins in the endoplasmic reticulum |
TUDCA | Ototoxicity | 3 | PM | 29751043 | 📋 | Tauroursodeoxycholic acid attenuates gentamicin-induced cochlear hair cell death in vitro |
TUDCA | Ototoxicity | 2 | PM | 29049998 | 📋 | Endoplasmic Reticulum Stress Is Involved in Cochlear Cell Apoptosis in a Cisplatin-Induced Ototoxicity Rat Model |
TUDCA | Phthalate Toxicity | 1 | PM | 33004990 | 📋 | Intrauterine exposure to low-dose DBP in the mice induces obesity in offspring via suppression of UCP1 mediated ER stress |
TUDCA | Statin-Induced Pathologies | 1 | PM | 30528737 | 📋 | C/EBP homologous protein deficiency inhibits statin-induced myotoxicity |
TUDCA | Tobacco Toxicity | 1 | PM | 26803847 | 📋 | Nicotine Directly Induces Endoplasmic Reticulum Stress Response in Rat Placental Trophoblast Giant Cells |