| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Astragalus Root | Acetaminophen Toxicity | 1 | PM | 35860733 | 📋 | Network Pharmacology-Based Prediction and Pharmacological Validation of Effects of Astragali Radix on Acetaminophen-Induced Liver Injury |
| Astragalus Root | Alcohol Toxicity | 1 | PM | 27355692 | 📋 | A Standardized Composition from Extracts of Myristica Fragrans, Astragalus Membranaceus, and Poria Cocos Protects Liver from Acute Ethanol Insult |
| Astragalus Root | Cardiotoxicity | 1 | PM | 34995692 | 📋 | Network-driven targeted analysis reveals that Astragali Radix alleviates doxorubicin-induced cardiotoxicity by maintaining fatty acid homeostasis |
| Astragalus Root | Cardiotoxicity | 3 | PM | 28460429 | 📋 | Cardioprotective mechanisms of phytochemicals against doxorubicin-induced cardiotoxicity |
| Astragalus Root | Cardiotoxicity | 2 | PM | 27902477 | 📋 | Astragalus polysaccharide restores autophagic flux and improves cardiomyocyte function in doxorubicin-induced cardiotoxicity |
| Astragalus Root | Cisplatin Toxicity | 2 | PM | 35561503 | 📋 | Investigating the inter-individual variability of Astragali Radix against cisplatin-induced liver injury via 16S rRNA gene sequencing and LC/MS-based metabolomics |
| Astragalus Root | Cisplatin Toxicity | 1 | PM | 34457031 | 📋 | Mechanism Prediction of Astragalus membranaceus against Cisplatin-Induced Kidney Damage by Network Pharmacology and Molecular Docking |
| Astragalus Root | Environmental Pollutants Toxicity | 1 | PM | 30243826 | 📋 | Astragali Radix and its compound formononetin ameliorate diesel particulate matter-induced skin barrier disruption by regulation of keratinocyte proliferation and apoptosis |
| Astragalus Root | Hepatotoxicity | 5 | PM | 38211994 | 📋 | [Protective effect and mechanism of Astragalus membranaceus and Angelica sinensis compatibility against triptolide-induced hepatotoxicity by regulating Keap1/Nrf2/PGC-1α] |
| Astragalus Root | Hepatotoxicity | 3 | PM | 35561503 | 📋 | Investigating the inter-individual variability of Astragali Radix against cisplatin-induced liver injury via 16S rRNA gene sequencing and LC/MS-based metabolomics |
| Astragalus Root | Hepatotoxicity | 1 | PM | 33834601 | 📋 | Protective Mechanism of Astragalus Polysaccharides against Cantharidin-induced Liver Injury Determined In Vivo by Liquid Chromatography/Mass Spectrometry Metabolomics |
| Astragalus Root | Hepatotoxicity | 2 | PM | 27564381 | 📋 | Hepatoprotective Activity of an Herbal Composition, MAP, a Standardized Blend Comprising Myristica fragrans, Astragalus membranaceus, and Poria cocos |
| Astragalus Root | Hepatotoxicity | 4 | PM | 25415237 | 📋 | Polysaccharides from Angelica and Astragalus exert hepatoprotective effects against carbon-tetrachloride-induced intoxication in mice |
| Astragalus Root | Immunotoxicity | 2 | PM | 38479258 | 📋 | Astragalus polysaccharides attenuate chemotherapy-induced immune injury by modulating gut microbiota and polyunsaturated fatty acid metabolism |
| Astragalus Root | Immunotoxicity | 1 | PM | 31818289 | 📋 | The combination of Radix Astragali and Radix Angelicae Sinensis attenuates the IFN-γ-induced immune destruction of hematopoiesis in bone marrow cells |
| Astragalus Root | Nephrotoxicity | 1 | PM | 33383113 | 📋 | Astragalus membranaceus and Salvia miltiorrhiza ameliorates cyclosporin A-induced chronic nephrotoxicity through the "gut-kidney axis" |
| Astragalus Root | Nephrotoxicity | 3 | PM | 29870890 | 📋 | Metabolomics coupled with system pharmacology reveal the protective effect of total flavonoids of Astragali Radix against adriamycin-induced rat nephropathy model |
| Astragalus Root | Nephrotoxicity | 2 | PM | 26719285 | 📋 | Protection against oxidative stress-induced apoptosis in kidney epithelium by Angelica and Astragalus |
| Astragalus Root | Neurotoxicity | 1 | PM | 33945017 | 📋 | Attenuation of doxorubicin-induced oxidative damage in rat brain by regulating amino acid homeostasis with Astragali Radix |
| Astragalus Root | Phthalate Toxicity | 1 | PM | 37984288 | 📋 | Combined Astragalus, vitamin C, and vitamin E alleviate DEHP-induced oxidative stress and the decreased of insulin synthesis and secretion in INS-1 cells |
| Astragalus Root | Reproductive Toxicity Male | 1 | PM | 22674751 | 📋 | Astragalus membranaceus ameliorates reproductive toxicity induced by cyclophosphamide in male mice |
