| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Andrographolide | Acetaminophen Toxicity | 1 | PM | 36518448 | 📋 | Hepatoprotective activity of andrographolide possibly through antioxidative defense mechanism in Sprague-Dawley rats |
| Andrographolide | Air Pollution Toxicity | 1 | PM | 34271116 | 📋 | Protective effect of the effective part of Andrographis paniculata (Burm.f.) Nees on PM 2.5-induced lung injury in rats by modulating the NF-κB pathway |
| Andrographolide | Aluminum Toxicity | 1 | PM | 38778607 | 📋 | Safeguarding Neuronal Integrity: Unveiling Possible Role of NFκB in the Neuroprotective Efficacy of Andrographolide Contrary to Aluminium Chloride-induced Neurotoxicity and Associated Spatial Memory Impairments in Rats |
| Andrographolide | Cardiotoxicity | 2 | PM | 38400848 | 📋 | An Integrated Network Pharmacology and RNA-seq Approach for Exploring the Protective Effect of Andrographolide in Doxorubicin-Induced Cardiotoxicity |
| Andrographolide | Cardiotoxicity | 1 | PM | 36335523 | 📋 | Andrographolide protects against doxorubicin-and arsenic trioxide-induced toxicity in cardiomyocytes |
| Andrographolide | Cisplatin Toxicity | 1 | PM | 33065471 | 📋 | Andrographolide suppresses cisplatin-induced endothelial hyperpermeability through activation of PI3K/Akt and eNOS -derived nitric oxide |
| Andrographolide | Copper Toxicity | 1 | PM | 20946909 | 📋 | Combination therapy with andrographolide and d-penicillamine enhanced therapeutic advantage over monotherapy with d-penicillamine in attenuating fibrogenic response and cell death in the periportal zone of liver in rats during copper toxicosis |
| Andrographolide | Hepatotoxicity | 2 | PM | 36518448 | 📋 | Hepatoprotective activity of andrographolide possibly through antioxidative defense mechanism in Sprague-Dawley rats |
| Andrographolide | Hepatotoxicity | 4 | PM | 23023025 | 📋 | Antioxidative and cytoprotective effects of andrographolide against CCl4-induced hepatotoxicity in HepG2 cells |
| Andrographolide | Hepatotoxicity | 3 | PM | 21947229 | 📋 | Protective effect of andrographolide against concanavalin A-induced liver injury |
| Andrographolide | Hepatotoxicity | 1 | PM | 19679627 | 📋 | Potency of andrographolide as an antitumor compound in BHC-induced liver damage |
| Andrographolide | Herbicide Toxicity | 2 | PM | 37275765 | 📋 | Andrographolide alleviates paraquat-induced acute lung injury by activating the Nrf2/HO-1 pathway |
| Andrographolide | Herbicide Toxicity | 1 | PM | 33576206 | 📋 | Andrographolide, an Antioxidant, Counteracts Paraquat- Induced Mutagenesis in Mammalian Cells |
| Andrographolide | Neurotoxicity | 2 | PM | 38778607 | 📋 | Safeguarding Neuronal Integrity: Unveiling Possible Role of NFκB in the Neuroprotective Efficacy of Andrographolide Contrary to Aluminium Chloride-induced Neurotoxicity and Associated Spatial Memory Impairments in Rats |
| Andrographolide | Neurotoxicity | 1 | PM | 28669260 | 📋 | Andrographolide attenuates microglia-mediated Aβ neurotoxicity partially through inhibiting NF-κB and JNK MAPK signaling pathway |
| Andrographolide | Pesticide Toxicity | 1 | PM | 19679627 | 📋 | Potency of andrographolide as an antitumor compound in BHC-induced liver damage |
| Andrographolide | Tobacco Toxicity | 6 | PM | 37987454 | 📋 | TXNIP-NLRP3-GSDMD axis-mediated inflammation and pyroptosis of islet β-cells is involved in cigarette smoke-induced hyperglycemia, which is alleviated by andrographolide |
| Andrographolide | Tobacco Toxicity | 2 | PM | 31128153 | 📋 | Andrographolide antagonizes the cigarette smoke-induced epithelial-mesenchymal transition and pulmonary dysfunction through anti-inflammatory inhibiting HOTAIR |
| Andrographolide | Tobacco Toxicity | 1 | PM | 30291937 | 📋 | Andrographolide simultaneously augments Nrf2 antioxidant defense and facilitates autophagic flux blockade in cigarette smoke-exposed human bronchial epithelial cells |
| Andrographolide | Tobacco Toxicity | 5 | PM | 27104764 | 📋 | Cigarette Smoke-Induced Lung Disease Predisposes to More Severe Infection with Nontypeable Haemophilus influenzae: Protective Effects of Andrographolide |
| Andrographolide | Tobacco Toxicity | 4 | PM | 23629921 | 📋 | Andrographolide protects against cigarette smoke-induced lung inflammation through activation of heme oxygenase-1 |
| Andrographolide | Tobacco Toxicity | 3 | PM | 23146110 | 📋 | Andrographolide protects against cigarette smoke-induced oxidative lung injury via augmentation of Nrf2 activity |
