Substance | Condition | Seq | Src | PMID | Dtl | Title |
Tanshinone | Ankylosing Spondylitis | 1 | PM | 36147634 | 📋 | Radix Salvia miltiorrhiza for Ankylosing Spondylitis: Determining Potential Inflammatory Molecular Targets and Mechanism Using Network Pharmacology |
Tanshinone | Bone Cancer | 2 | PM | 35744840 | 📋 | Dihydrotanshinone I Enhances Cell Adhesion and Inhibits Cell Migration in Osteosarcoma U-2 OS Cells through CD44 and Chemokine Signaling |
Tanshinone | Bone Cancer | 1 | PM | 32496906 | 📋 | Tanshinone IIA inhibits osteosarcoma growth through modulation of AMPK-Nrf2 signaling pathway |
Tanshinone | Bone Fractures | 1 | PM | 38783358 | 📋 | Local Application of Tanshinone IIA protects mesenchymal stem cells from apoptosis and promotes fracture healing in ovariectomized mice |
Tanshinone | Degenerative Disk Disease | 1 | PM | 34676010 | 📋 | Tanshinone IIA and Astragaloside IV Inhibit miR-223/JAK2/STAT1 Signalling Pathway to Alleviate Lipopolysaccharide-Induced Damage in Nucleus Pulposus Cells |
Tanshinone | Gout | 1 | PM | 36578443 | 📋 | Tanshinone IIA Improves Acute Gouty Arthritis in Rats through Regulating Neutrophil Activation and the NLRP3 Inflammasome |
Tanshinone | Osteoarthritis | 5 | PM | 38253247 | 📋 | Tanshinone IIA attenuates osteoarthritis via inhibiting aberrant angiogenesis in subchondral bone |
Tanshinone | Osteoarthritis | 4 | PM | 38137512 | 📋 | Tanshinone IIA Facilitates Efficient Cartilage Regeneration under Inflammatory Factors Caused Stress via Upregulating LncRNA NEAT1_2 |
Tanshinone | Osteoarthritis | 3 | PM | 37589005 | 📋 | Tanshinone IIA alleviates chondrocyte apoptosis and extracellular matrix degeneration by inhibiting ferroptosis |
Tanshinone | Osteoarthritis | 1 | PM | 30193597 | 📋 | [Effect of Compound Medicine of Tanshinone 2A and Resveratrol on Peak Bone Mass in Growing Rats] |
Tanshinone | Osteoarthritis | 2 | PM | 29679904 | 📋 | Tanshinone IIA protects murine chondrogenic ATDC5 cells from lipopolysaccharide-induced inflammatory injury by down-regulating microRNA-203a |
Tanshinone | Osteonecrosis | 2 | PM | 37391758 | 📋 | Tanshinone I alleviates steroid-induced osteonecrosis of femoral heads and promotes angiogenesis: in vivo and in vitro studies |
Tanshinone | Osteonecrosis | 1 | PM | 35111227 | 📋 | Tanshinone I Mitigates Steroid-Induced Osteonecrosis of the Femoral Head and Activates the Nrf2 Signaling Pathway in Rats |
Tanshinone | Osteoporosis | 1 | PM | 35419360 | 📋 | Tanshinone Ameliorates Glucocorticoid-Induced Bone Loss via Activation of AKT1 Signaling Pathway |
Tanshinone | Postmenopausal Osteoporosis | 1 | PM | 38064814 | 📋 | Tanshinone I attenuates estrogen-deficiency bone loss via inhibiting RANKL-induced MAPK and NF-κB signaling pathways |
Tanshinone | Rheumatoid Arthritis | 3 | PM | 37189204 | 📋 | Tanshinone IIA inhibits osteoclastogenesis in rheumatoid arthritis via LDHC-regulated ROS generation |
Tanshinone | Rheumatoid Arthritis | 2 | PM | 36852883 | 📋 | Tanshinone IIA relieves arthritis by inhibiting autophagy of fibroblast-like synoviocytes via matrix metalloproteinase9/receptor for advanced glycation end product/toll-like receptor 9 signal axis in mice with collagen-induced arthritis |
Tanshinone | Rheumatoid Arthritis | 1 | PM | 32499694 | 📋 | Tanshinone IIA Suppresses Proliferation and Inflammatory Cytokine Production of Synovial Fibroblasts from Rheumatoid Arthritis Patients Induced by TNF-α and Attenuates the Inflammatory Response in AIA Mice |
Tanshinone | Spinal Cord Injury | 4 | PM | 38552937 | 📋 | Sodium tanshinone IIA sulfonate suppresses microglia polarization and neuroinflammation possibly via regulating miR-125b-5p/STAT3 axis to ameliorate neuropathic pain |
Tanshinone | Spinal Cord Injury | 3 | PM | 37808475 | 📋 | Possible mechanisms of treatment for spinal cord injury repair with tanshinone IIA |
Tanshinone | Spinal Cord Injury | 2 | PM | 37727797 | 📋 | Tanshinone IIA protects motor neuron-like NSC-34 cells against lipopolysaccharide-induced cell injury by the regulation of the lncRNA TCTN2/miR-125a-5p/DUSP1 axis |
Tanshinone | Spinal Cord Injury | 1 | PM | 30001730 | 📋 | Tanshinone IIA promotes the differentiation of bone marrow mesenchymal stem cells into neuronal-like cells in a spinal cord injury model |