| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Genistein | Bone Cancer | 3 | PM | 38030209 | 📋 | Genistein Induces Antiproliferative Activity and Apoptosis in Human Osteosarcoma Saos-2 Cells |
| Genistein | Bone Cancer | 1 | PM | 23013480 | 📋 | Genistein Inhibits Cell Invasion and Motility by Inducing Cell Differentiation in Murine Osteosarcoma Cell Line LM8 |
| Genistein | Bone Cancer | 2 | PM | 20038829 | 📋 | Enhanced Anticancer Effect of Gemcitabine by Genistein in Osteosarcoma: The Role of Akt and Nuclear factor-kappaB |
| Genistein | Bone Disease | 1 | PM | 36160403 | 📋 | The protective activity of genistein against bone and cartilage diseases |
| Genistein | Bone Formation | 7 | PM | 33853499 | 📋 | Genistein Triggers Translocation of Estrogen Receptor-Alpha in Mitochondria to Induce Expressions of ATP Synthesis-Associated Genes and Improves Energy Production and Osteoblast Maturation |
| Genistein | Bone Formation | 1 | PM | 32917180 | 📋 | Genistein contributes to cell cycle progression and regulates oxidative stress in primary culture of osteoblasts along with osteoclasts attenuation |
| Genistein | Bone Formation | 2 | PM | 19332450 | 📋 | Protective Effect of Genistein Aglycone on the Development of Osteonecrosis of the Femoral Head and Secondary Osteoporosis Induced by Methylprednisolone in Rats |
| Genistein | Bone Formation | 5 | PM | 19302595 | 📋 | Genistein Aglycone Reverses Glucocorticoid-Induced Osteoporosis and Increases Bone Breaking Strength in Rats: A Comparative Study With Alendronate |
| Genistein | Bone Formation | 4 | PM | 18796517 | 📋 | Breast Safety and Efficacy of Genistein Aglycone for Postmenopausal Bone Loss: A Follow-Up Study |
| Genistein | Bone Formation | 6 | PM | 16410641 | 📋 | Bone Formation-Promoting Effect of Genistein on Marrow Mesenchymal Cell Culture |
| Genistein | Bone Formation | 3 | PM | 12369794 | 📋 | Effects of Genistein and Hormone-Replacement Therapy on Bone Loss in Early Postmenopausal Women: A Randomized Double-Blind Placebo-Controlled Study |
| Genistein | Bone Fractures | 2 | PM | 32897066 | 📋 | Genistein Improves Bone Healing via Triggering Estrogen Receptor Alpha-Mediated Expressions of Osteogenesis-Associated Genes and Consequent Maturation of Osteoblasts |
| Genistein | Bone Fractures | 1 | PM | 31750414 | 📋 | Bone Strength Is Improved With Genistein Treatment in Mice With Diet-Induced Obesity |
| Genistein | Bone Health | 2 | PM | 37292353 | 📋 | Isoflavones and probiotics effect on bone calcium and bone cells in rats |
| Genistein | Bone Health | 1 | PM | 28560445 | 📋 | Genistein and menaquinone-4 treatment-induced alterations in the expression of mRNAs and their products are beneficial to osteoblastic MC3T3-E1 cell functions |
| Genistein | Cartilage Disease | 1 | PM | 36160403 | 📋 | The protective activity of genistein against bone and cartilage diseases |
| Genistein | Cartilage Injury | 1 | PM | 38775854 | 📋 | Genistein promotes cartilage repair and inhibits synovial inflammatory response after anterior cruciate ligament transection in rats by regulating the Wnt/β-catenin axis |
| Genistein | Diabetic Osteoporosis | 1 | PM | 33447176 | 📋 | Genistein prevents bone loss in type 2 diabetic rats induced by streptozotocin |
| Genistein | Osteoarthritis | 5 | PM | 38775854 | 📋 | Genistein promotes cartilage repair and inhibits synovial inflammatory response after anterior cruciate ligament transection in rats by regulating the Wnt/β-catenin axis |
| Genistein | Osteoarthritis | 4 | PM | 37755294 | 📋 | Genistein Suppresses IL-6 and MMP-13 to Attenuate Osteoarthritis in Obese Diabetic Mice |
| Genistein | Osteoarthritis | 3 | PM | 32582961 | 📋 | Anti‑chondrocyte Apoptosis Effect of Genistein in Treating inflammation‑induced Osteoarthritis |
| Genistein | Osteoarthritis | 1 | PM | 32083119 | 📋 | Protective Effect of Genistein on Condylar Cartilage Through Downregulating NF- κ B Expression in Experimentally Created Osteoarthritis Rats |
| Genistein | Osteoarthritis | 2 | PM | 31671813 | 📋 | Genistein as Potential Therapeutic Candidate for Menopausal Symptoms and Other Related Diseases |
| Genistein | Osteoarthritis of the Knee | 1 | PM | 33989507 | 📋 | The articular cartilage preservative effects of genistein in an experimental model of knees osteoarthritis |
| Genistein | Osteolysis | 1 | PM | 32917180 | 📋 | Genistein contributes to cell cycle progression and regulates oxidative stress in primary culture of osteoblasts along with osteoclasts attenuation |
| Genistein | Osteomyelitis | 1 | PM | 36727417 | 📋 | Antibacterial and anti-inflammatory effects of genistein in Staphylococcus aureus induced osteomyelitis in rats |
| Genistein | Osteonecrosis | 1 | PM | 19332450 | 📋 | Protective Effect of Genistein Aglycone on the Development of Osteonecrosis of the Femoral Head and Secondary Osteoporosis Induced by Methylprednisolone in Rats |
| Genistein | Osteopenia | 4 | PM | 20013821 | 📋 | Effects of Isoflavones Equol and Genistein on Bone Quality in a Rat Osteopenia Model |
| Genistein | Osteopenia | 3 | PM | 18796517 | 📋 | Breast Safety and Efficacy of Genistein Aglycone for Postmenopausal Bone Loss: A Follow-Up Study |
| Genistein | Osteopenia | 5 | PM | 18695641 | 📋 | Effects of Genistein Aglycone in Osteoporotic, Ovariectomized Rats: A Comparison With Alendronate, Raloxifene and Oestradiol |
| Genistein | Osteopenia | 2 | PM | 17682090 | 📋 | Effects of the Phytoestrogen Genistein on Some Predictors of Cardiovascular Risk in Osteopenic, Postmenopausal Women: A Two-Year Randomized, Double-Blind, Placebo-Controlled Study |
| Genistein | Osteopenia | 6 | PM | 12429999 | 📋 | Stimulatory Effect of menaquinone-7 on Bone Formation in Elderly Female Rat Femoral Tissues in Vitro: Prevention of Bone Deterioration With Aging |
| Genistein | Osteopenia | 1 | PM | 12369794 | 📋 | Effects of Genistein and Hormone-Replacement Therapy on Bone Loss in Early Postmenopausal Women: A Randomized Double-Blind Placebo-Controlled Study |
| Genistein | Osteoporosis | 12 | PM | 37767998 | 📋 | Insights into the antiosteoporotic mechanism of the soy-derived isoflavone genistein: Modulation of the Wnt/beta-catenin signaling |
| Genistein | Osteoporosis | 6 | PM | 36296984 | 📋 | The Nutraceutical Genistein-Lycopene Combination Improves Bone Damage Induced by Glucocorticoids by Stimulating the Osteoblast Formation Process |
| Genistein | Osteoporosis | 8 | PM | 32897066 | 📋 | Genistein Improves Bone Healing via Triggering Estrogen Receptor Alpha-Mediated Expressions of Osteogenesis-Associated Genes and Consequent Maturation of Osteoblasts |
| Genistein | Osteoporosis | 5 | PM | 20036112 | 📋 | Evaluation of Bone Quality and Quantity in Osteoporotic Mice--The Effects of Genistein and Equol |
| Genistein | Osteoporosis | 4 | PM | 19793844 | 📋 | Genistein and a Soy Extract Differentially Affect Three-Dimensional Bone Parameters and Bone-Specific Gene Expression in Ovariectomized Mice |
| Genistein | Osteoporosis | 7 | PM | 19302595 | 📋 | Genistein Aglycone Reverses Glucocorticoid-Induced Osteoporosis and Increases Bone Breaking Strength in Rats: A Comparative Study With Alendronate |
| Genistein | Osteoporosis | 3 | PM | 18796517 | 📋 | Breast Safety and Efficacy of Genistein Aglycone for Postmenopausal Bone Loss: A Follow-Up Study |
| Genistein | Osteoporosis | 9 | PM | 18600400 | 📋 | Effects of Genistein on Vertebral Trabecular Bone Microstructure, Bone Mineral Density, Microcracks, Osteocyte Density, and Bone Strength in Ovariectomized Rats |
| Genistein | Osteoporosis | 2 | PM | 17577003 | 📋 | Effects of the Phytoestrogen Genistein on Bone Metabolism in Osteopenic Postmenopausal Women: A Randomized Trial |
| Genistein | Osteoporosis | 11 | PM | 16410641 | 📋 | Bone Formation-Promoting Effect of Genistein on Marrow Mesenchymal Cell Culture |
| Genistein | Osteoporosis | 10 | PM | 12429999 | 📋 | Stimulatory Effect of menaquinone-7 on Bone Formation in Elderly Female Rat Femoral Tissues in Vitro: Prevention of Bone Deterioration With Aging |
| Genistein | Osteoporosis | 1 | PM | 12369794 | 📋 | Effects of Genistein and Hormone-Replacement Therapy on Bone Loss in Early Postmenopausal Women: A Randomized Double-Blind Placebo-Controlled Study |
| Genistein | Postmenopausal Osteoporosis | 2 | PM | 36871183 | 📋 | Genistein mitigates senescence of bone marrow mesenchymal stem cells via ERR?-mediated mitochondrial biogenesis and mitophagy in ovariectomized rats |
| Genistein | Postmenopausal Osteoporosis | 1 | PM | 18695641 | 📋 | Effects of Genistein Aglycone in Osteoporotic, Ovariectomized Rats: A Comparison With Alendronate, Raloxifene and Oestradiol |
| Genistein | Rheumatoid Arthritis | 1 | PM | 32440504 | 📋 | Genistein Inhibits Angiogenesis Developed During Rheumatoid Arthritis Through the IL-6/JAK2/STAT3/VEGF Signalling Pathway |
| Genistein | Sciatica | 1 | PM | 18691380 | 📋 | Genistein, a Natural Phytoestrogen From Soy, Relieves Neuropathic Pain Following Chronic Constriction Sciatic Nerve Injury in Mice: Anti-Inflammatory and Antioxidant Activity |
