| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Fisetin | Bone Cancer | 3 | PM | 31044527 | 📋 | Fisetin activates Hippo pathway and JNK/ERK/AP-1 signaling to inhibit proliferation and induce apoptosis of human osteosarcoma cells via ZAK overexpression |
| Fisetin | Bone Cancer | 2 | PM | 31028200 | 📋 | Fistein Suppresses Human Osteosarcoma U-2 OS Cell Migration and Invasion via Affecting FAK, uPA and NF-ĸB Signaling Pathway In Vitro |
| Fisetin | Bone Cancer | 1 | PM | 29270805 | 📋 | Combination of etoposide and fisetin results in anti-cancer efficiency against osteosarcoma cell models |
| Fisetin | Bone Formation | 3 | PM | 35811886 | 📋 | Osteogenic Effect of Fisetin Doping in Bioactive Glass/Poly(caprolactone) Hybrid Scaffolds |
| Fisetin | Bone Formation | 2 | PM | 35652047 | 📋 | Fisetin: An Integrated Approach to Identify a Strategy Promoting Osteogenesis |
| Fisetin | Bone Formation | 1 | PM | 34256044 | 📋 | Fisetin promotes osteoblast differentiation and osteogenesis through GSK-3β phosphorylation at Ser9 and consequent β-catenin activation, inhibiting osteoporosis |
| Fisetin | Degenerative Disk Disease | 1 | PM | 38145645 | 📋 | Fisetin suppresses ferroptosis through Nrf2 and attenuates intervertebral disc degeneration in rats |
| Fisetin | Osteoarthritis | 2 | PM | 38278314 | 📋 | Fisetin suppresses chondrocyte senescence and attenuates osteoarthritis progression by targeting sirtuin 6 |
| Fisetin | Osteoarthritis | 1 | PM | 28213268 | 📋 | Fisetin inhibits IL-1β-induced inflammatory response in human osteoarthritis chondrocytes through activating SIRT1 and attenuates the progression of osteoarthritis in mice |
| Fisetin | Osteoporosis | 8 | PM | 38805428 | 📋 | Osteoporosis induced by cellular senescence: A mathematical model |
| Fisetin | Osteoporosis | 5 | PM | 37087476 | 📋 | Network pharmacology identifies fisetin as a treatment for osteoporosis that activates the Wnt/β-catenin signaling pathway in BMSCs |
| Fisetin | Osteoporosis | 4 | PM | 36875869 | 📋 | The Senolytic Drug Fisetin Attenuates Bone Degeneration in the Zmpste24 -/- Progeria Mouse Model |
| Fisetin | Osteoporosis | 3 | PM | 36243333 | 📋 | The effects of fisetin on bone and cartilage: A systematic review |
| Fisetin | Osteoporosis | 2 | PM | 34256044 | 📋 | Fisetin promotes osteoblast differentiation and osteogenesis through GSK-3β phosphorylation at Ser9 and consequent β-catenin activation, inhibiting osteoporosis |
| Fisetin | Osteoporosis | 1 | PM | 33645479 | 📋 | Connectivity map analysis identifies fisetin as a treatment compound for osteoporosis through activating the PI3K-AKT signaling pathway in mouse pre-osteoblastic MC3T3-E1 cells |
| Fisetin | Osteoporosis | 7 | PM | 23861901 | 📋 | The polyphenol fisetin protects bone by repressing NF-κB and MKP-1-dependent signaling pathways in osteoclasts |
| Fisetin | Osteoporosis | 6 | PM | 23008743 | 📋 | Fisetin Inhibits Osteoclast Differentiation via Downregulation of p38 and c-Fos-NFATc1 Signaling Pathways |
| Fisetin | Postmenopausal Osteoporosis | 1 | PM | 35013033 | 📋 | Anti-osteoporosis Effect of Fisetin against Ovariectomy Induced Osteoporosis in Rats: In silico, in vitro and in vivo Activity |
| Fisetin | Spinal Cord Injury | 2 | PM | 38428149 | 📋 | Fisetin orchestrates neuroinflammation resolution and facilitates spinal cord injury recovery through enhanced autophagy in pro-inflammatory glial cells |
| Fisetin | Spinal Cord Injury | 1 | PM | 33470764 | 📋 | Neuroprotective potential of fisetin in an experimental model of spinal cord injury: via modulation of NF-κB/IκBα pathway |
