| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| EGCG | Arthritis | 2 | PM | 36307395 | 📋 | Epigallocatechin-3-gallate inhibits osteoclastic differentiation by modulating mitophagy and mitochondrial functions |
| EGCG | Arthritis | 1 | PM | 26957211 | 📋 | Epigallocatechin-3-gallate Ameliorates Autoimmune Arthritis by Reciprocal Regulation of T helper-17 Regulatory T Cells and Inhibition of Osteoclastogenesis by Inhibiting STAT3 Signaling |
| EGCG | Bone Cancer | 5 | PM | 35348430 | 📋 | Epigallocatechin-3-gallate suppresses the growth of human osteosarcoma by inhibiting the Wnt/β-catenin signalling pathway |
| EGCG | Bone Cancer | 2 | PM | 26499783 | 📋 | Green Tea Polyphenol EGCG Suppresses Osteosarcoma Cell Growth Through Upregulating miR-1 |
| EGCG | Bone Cancer | 1 | PM | 26363974 | 📋 | Epigallocatechin-3-gallate Attenuates Bone Cancer Pain Involving Decreasing Spinal Tumor Necrosis Factor-α Expression in a Mouse Model |
| EGCG | Bone Cancer | 3 | PM | 25510179 | 📋 | Overexpression of miR-126 Sensitizes Osteosarcoma Cells to Apoptosis Induced by epigallocatechin-3-gallate |
| EGCG | Bone Cancer | 4 | PM | 16756080 | 📋 | Inhibition of proliferation and induction of apoptosis by EGCG in human osteogenic sarcoma (HOS) cells |
| EGCG | Bone Disease | 1 | PM | 28849144 | 📋 | Amplification by (‑)‑epigallocatechin gallate of prostaglandin F2α‑stimulated synthesis of osteoprotegerin in osteoblasts |
| EGCG | Bone Formation | 5 | PM | 31114166 | 📋 | Epigallocatechin-3-gallate enhances the osteoblastogenic differentiation of human adipose-derived stem cells |
| EGCG | Bone Formation | 4 | PM | 30563251 | 📋 | (-)-Epigallocatechin-3-Gallate (EGCG) Enhances Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells |
| EGCG | Bone Formation | 1 | PM | 30501071 | 📋 | Osteogenesis of Multipotent Progenitor Cells Using the Epigallocatechin Gallate-Modified Gelatin Sponge Scaffold in the Rat Congenital Cleft-Jaw Model |
| EGCG | Bone Formation | 2 | PM | 26748399 | 📋 | Epigallocatechin-3-gallate Protects Against Tumor Necrosis Factor Alpha Induced Inhibition of Osteogenesis of Mesenchymal Stem Cells |
| EGCG | Bone Formation | 3 | PM | 26602917 | 📋 | Application of Green Tea Catechin for Inducing the Osteogenic Differentiation of Human Dedifferentiated Fat Cells in Vitro |
| EGCG | Bone Fractures | 2 | PM | 32316306 | 📋 | Green Tea Catechin (-)-Epigallocatechin-3-Gallate (EGCG) Facilitates Fracture Healing |
| EGCG | Bone Fractures | 1 | PM | 30501071 | 📋 | Osteogenesis of Multipotent Progenitor Cells Using the Epigallocatechin Gallate-Modified Gelatin Sponge Scaffold in the Rat Congenital Cleft-Jaw Model |
| EGCG | Degenerative Disk Disease | 3 | PM | 34803694 | 📋 | (-)-Epigallocatechin-3-gallate Ameliorates Intervertebral Disc Degeneration Through Reprogramming of the Circadian Clock |
| EGCG | Degenerative Disk Disease | 2 | PM | 32546974 | 📋 | Epigallocatechin-3-Gallate Protects H 2 O 2-Induced Nucleus Pulposus Cell Apoptosis and Inflammation by Inhibiting cGAS/Sting/NLRP3 Activation |
| EGCG | Degenerative Disk Disease | 1 | PM | 27119009 | 📋 | The Natural Polyphenol Epigallocatechin Gallate Protects Intervertebral Disc Cells From Oxidative Stress |
| EGCG | Gout | 1 | PM | 27234527 | 📋 | Epigallocatechin Gallate Inhibits Urate Crystals-Induced Peritoneal Inflammation in C57BL/6 Mice |
| EGCG | Osteoarthritis | 9 | PM | 38259454 | 📋 | J-shaped association of dietary catechins intake with the prevalence of osteoarthritis and moderating effect of physical activity: an American population-based cohort study |
| EGCG | Osteoarthritis | 7 | PM | 35426252 | 📋 | Epigallocatechin-3-O-Gallate Ameliorates Oxidative Stress-Induced Chondrocyte Dysfunction and Exerts Chondroprotective Effects via the Keap1/Nrf2/ARE Signaling Pathway |
| EGCG | Osteoarthritis | 6 | PM | 35260041 | 📋 | Epigallocatechin-3- O-gallate promotes extracellular matrix and inhibits inflammation in IL-1β stimulated chondrocytes by the PTEN/miRNA-29b pathway |
| EGCG | Osteoarthritis | 5 | PM | 33530594 | 📋 | Intra-Articular Injection of (-)-Epigallocatechin 3-Gallate (EGCG) Ameliorates Cartilage Degeneration in Guinea Pigs with Spontaneous Osteoarthritis |
| EGCG | Osteoarthritis | 4 | PM | 33374730 | 📋 | Intra-Articular Injection of (-)-Epigallocatechin 3-Gallate to Attenuate Articular Cartilage Degeneration by Enhancing Autophagy in a Post-Traumatic Osteoarthritis Rat Model |
| EGCG | Osteoarthritis | 8 | PM | 28110479 | 📋 | Epigallocatechin-3-O-gallate modulates global microRNA expression in interleukin-1β-stimulated human osteoarthritis chondrocytes: potential role of EGCG on negative co-regulation of microRNA-140-3p and ADAMTS5 |
| EGCG | Osteoarthritis | 3 | PM | 21345249 | 📋 | Molecular Targets of Natural Health Products in Arthritis |
| EGCG | Osteoarthritis | 2 | PM | 19748608 | 📋 | Inhibition of cyclooxygenase-2 Expression and Prostaglandin E2 Production in Chondrocytes by Avocado Soybean Unsaponifiables and Epigallocatechin Gallate |
| EGCG | Osteoarthritis | 1 | PM | 19445683 | 📋 | Green Tea Polyphenol epigallocatechin-3-gallate Inhibits Advanced Glycation End Product-Induced Expression of Tumor Necrosis Factor-Alpha and Matrix metalloproteinase-13 in Human Chondrocytes |
| EGCG | Osteomyelitis | 1 | PM | 17644710 | 📋 | Epigallocatechin Gallate Suppresses Expression of Receptor Activator of NF-kappaB Ligand (RANKL) in Staphylococcus Aureus Infection in Osteoblast-Like NRG Cells |
| EGCG | Osteopenia | 1 | PM | 23511703 | 📋 | (-)-Epigallocatechin-3-gallate improves bone microarchitecture in ovariectomized rats |
| EGCG | Osteoporosis | 6 | PM | 37953732 | 📋 | Epigallocatechin gallate alleviates osteoporosis by regulating the gut microbiota and serum metabolites in rats |
| EGCG | Osteoporosis | 5 | PM | 33677256 | 📋 | (-)-Epigallocatechin-3-gallate inhibits osteoclastogenesis by blocking RANKL-RANK interaction and suppressing NF-κB and MAPK signaling pathways |
| EGCG | Osteoporosis | 4 | PM | 33268671 | 📋 | (-)-Epigallocatechin-3-gallate inhibits RANKL-induced osteoclastogenesis via downregulation of NFATc1 and suppression of HO-1-HMGB1-RAGE pathway |
| EGCG | Osteoporosis | 3 | PM | 32422565 | 📋 | Selective Dietary Polyphenols Induce Differentiation of Human Osteoblasts by Adiponectin Receptor 1-mediated Reprogramming of Mitochondrial Energy Metabolism |
| EGCG | Osteoporosis | 2 | PM | 29867459 | 📋 | Epigallocatechin-3-Gallate Ameliorates Glucocorticoid-Induced Osteoporosis of Rats in Vivo and in Vitro |
| EGCG | Osteoporosis | 1 | PM | 22434366 | 📋 | (-)-Epigallocathechin-3-gallate, an AMPK Activator, Decreases Ovariectomy-Induced Bone Loss by Suppression of Bone Resorption |
| EGCG | Rheumatoid Arthritis | 9 | PM | 35829999 | 📋 | Epigallocatechin-3-Gallate Pretreatment Improves Autologous Adipose-derived Stem Cells Against Rheumatoid Arthritis-induced Neuroinflammation in the Brain of Collagen-induced Rats |
| EGCG | Rheumatoid Arthritis | 8 | PM | 35423998 | 📋 | Hyaluronic acid-green tea catechin conjugates as a potential therapeutic agent for rheumatoid arthritis |
| EGCG | Rheumatoid Arthritis | 3 | PM | 31746064 | 📋 | Epigallocatechin 3-gallate Attenuates Arthritis by Regulating Nrf2, HO-1, and Cytokine Levels in an Experimental Arthritis Model |
| EGCG | Rheumatoid Arthritis | 4 | PM | 27023113 | 📋 | Long-Term Effects of (-)-Epigallocatechin Gallate (EGCG) on Pristane-Induced Arthritis (PIA) in Female Dark Agouti Rats |
| EGCG | Rheumatoid Arthritis | 7 | PM | 26748399 | 📋 | Epigallocatechin-3-gallate Protects Against Tumor Necrosis Factor Alpha Induced Inhibition of Osteogenesis of Mesenchymal Stem Cells |
| EGCG | Rheumatoid Arthritis | 1 | PM | 26379475 | 📋 | Green Tea Epigallocatechin-3-Gallate Suppresses Autoimmune Arthritis Through Indoleamine-2,3-Dioxygenase Expressing Dendritic Cells and the Nuclear Factor, Erythroid 2-Like 2 Antioxidant Pathway |
| EGCG | Rheumatoid Arthritis | 10 | PM | 23871988 | 📋 | Potential benefits of green tea polyphenol EGCG in the prevention and treatment of vascular inflammation in rheumatoid arthritis |
| EGCG | Rheumatoid Arthritis | 2 | PM | 21345249 | 📋 | Molecular Targets of Natural Health Products in Arthritis |
| EGCG | Rheumatoid Arthritis | 5 | PM | 19404960 | 📋 | Down-regulation of Myeloid Cell Leukemia 1 by epigallocatechin-3-gallate Sensitizes Rheumatoid Arthritis Synovial Fibroblasts to Tumor Necrosis Factor Alpha-Induced Apoptosis |
| EGCG | Rheumatoid Arthritis | 6 | PM | 18496696 | 📋 | Epigallocatechin-3-gallate Suppresses TNF-alpha -Induced Production of MMP-1 and -3 in Rheumatoid Arthritis Synovial Fibroblasts |
| EGCG | Sciatica | 1 | PM | 22573016 | 📋 | (-)-Epigallocatechin-3-gallate (EGCG) attenuates functional deficits and morphological alterations by diminishing apoptotic gene overexpression in skeletal muscles after sciatic nerve crush injury |
| EGCG | Spinal Cord Injury | 9 | PM | 37499782 | 📋 | Hyperbaric oxygen in combination with epigallocatechin-3-gallate synergistically enhance recovery from spinal cord injury in rats |
| EGCG | Spinal Cord Injury | 4 | PM | 36829922 | 📋 | The Role of Green Tea Catechin Epigallocatechin Gallate (EGCG) and Mammalian Target of Rapamycin (mTOR) Inhibitor PP242 (Torkinib) in the Treatment of Spinal Cord Injury |
| EGCG | Spinal Cord Injury | 3 | PM | 33335755 | 📋 | EGCG modulates PKD1 and ferroptosis to promote recovery in ST rats |
| EGCG | Spinal Cord Injury | 8 | PM | 31809244 | 📋 | Assessment of the neuroprotective effects of (-)-epigallocatechin-3-gallate on spinal cord ischemia-reperfusion injury in rats |
| EGCG | Spinal Cord Injury | 7 | PM | 28899730 | 📋 | A green tea polyphenol epigallocatechin-3-gallate enhances neuroregeneration after spinal cord injury by altering levels of inflammatory cytokines |
| EGCG | Spinal Cord Injury | 1 | PM | 25314656 | 📋 | Polyphenols From Green Tea Prevent Antineuritogenic Action of Nogo-A via 67-kDa Laminin Receptor and Hydrogen Peroxide |
| EGCG | Spinal Cord Injury | 6 | PM | 24071567 | 📋 | (-)-Epigallocatechin-3-gallate (EGCG) modulates neurological function when intravenously infused in acute and, chronically injured spinal cord of adult rats |
| EGCG | Spinal Cord Injury | 5 | PM | 23831998 | 📋 | Anti-edema effect of epigallocatechin gallate on spinal cord injury in rats |
| EGCG | Spinal Cord Injury | 2 | PM | 19815005 | 📋 | Effects of epigallocatechin gallate on tissue protection and functional recovery after contusive spinal cord injury in rats |
| EGCG | Spondyloarthritis | 1 | PM | 34153673 | 📋 | Epigallocatechin gallate regulates inflammatory responses and new bone formation through Wnt/β-Catenin/COX-2 pathway in spondyloarthritis |
