| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Astragalosides | Arthritis | 1 | PM | 26936538 | 📋 | Astragaloside IV Suppresses Inflammatory Mediator Production in Synoviocytes and collagen‑induced Arthritic Rats |
| Astragalosides | Bone Cancer | 1 | PM | 29128795 | 📋 | Chemosensitive effects of Astragaloside IV in osteosarcoma cells via induction of apoptosis and regulation of caspase-dependent Fas/FasL signaling |
| Astragalosides | Bone Disease | 1 | PM | 27397144 | 📋 | Astragaloside I Stimulates Osteoblast Differentiation Through the Wnt/β-catenin Signaling Pathway |
| Astragalosides | Bone Formation | 1 | PM | 33994865 | 📋 | Accelerated Bone Regeneration by Astragaloside IV through Stimulating the Coupling of Osteogenesis and Angiogenesis |
| Astragalosides | Degenerative Disk Disease | 4 | PM | 37603510 | 📋 | Astragaloside IV relieves IL-1β-induced human nucleus pulposus cells degeneration through modulating PI3K/Akt signaling pathway |
| Astragalosides | Degenerative Disk Disease | 3 | PM | 36527065 | 📋 | Astragaloside IV attenuates IL-1β-induced intervertebral disc degeneration through inhibition of the NF-κB pathway |
| Astragalosides | Degenerative Disk Disease | 2 | PM | 34676010 | 📋 | Tanshinone IIA and Astragaloside IV Inhibit miR-223/JAK2/STAT1 Signalling Pathway to Alleviate Lipopolysaccharide-Induced Damage in Nucleus Pulposus Cells |
| Astragalosides | Degenerative Disk Disease | 1 | PM | 34630680 | 📋 | Cycloastragenol and Astragaloside IV activate telomerase and protect nucleus pulposus cells against high glucose-induced senescence and apoptosis |
| Astragalosides | Osteoarthritis | 4 | PM | 37855351 | 📋 | Astragaloside IV Protects Against IL-1β-Induced Chondrocyte Damage via Activating Autophagy |
| Astragalosides | Osteoarthritis | 3 | PM | 31906765 | 📋 | Astragaloside IV Protects ATDC5 Cells From Lipopolysaccharide-Caused Damage Through Regulating miR-203/MyD88 |
| Astragalosides | Osteoarthritis | 1 | PM | 31293216 | 📋 | Astragaloside Inhibits IL-1β-induced Inflammatory Response in Human Osteoarthritis Chondrocytes and Ameliorates the Progression of Osteoarthritis in Mice |
| Astragalosides | Osteoarthritis | 2 | PM | 28714008 | 📋 | Astragaloside IV Protects Against Apoptosis in Human Degenerative Chondrocytes Through Autophagy Activation |
| Astragalosides | Osteoarthritis of the Knee | 1 | PM | 36403512 | 📋 | Astragaloside IV as a novel CXCR4 antagonist alleviates osteoarthritis in the knee of monosodium iodoacetate-induced rats |
| Astragalosides | Osteonecrosis | 2 | PM | 37186483 | 📋 | Effects of astragaloside IV on glucocorticoid-induced avascular necrosis of the femoral head via regulating Akt-related pathways |
| Astragalosides | Osteonecrosis | 1 | PM | 33563553 | 📋 | Astragaloside IV ameliorates steroid-induced osteonecrosis of the femoral head by repolarizing the phenotype of pro-inflammatory macrophages |
| Astragalosides | Osteoporosis | 4 | PM | 38290207 | 📋 | Astragaloside IV alleviates macrophage senescence and d-galactose-induced bone loss in mice through STING/NF-κB pathway |
| Astragalosides | Osteoporosis | 3 | PM | 34620219 | 📋 | Astragaloside positively regulated osteogenic differentiation of pre-osteoblast MC3T3-E1 through PI3K/Akt signaling pathway |
| Astragalosides | Osteoporosis | 2 | PM | 33445204 | 📋 | Astragaloside IV protects against iron loading-induced abnormal differentiation of bone marrow mesenchymal stem cells (BMSCs) |
| Astragalosides | Osteoporosis | 1 | PM | 33179111 | 📋 | Astragaloside‑IV modulates NGF‑induced osteoblast differentiation via the GSK3β/β‑catenin signalling pathway |
| Astragalosides | Postmenopausal Osteoporosis | 1 | PM | 22426655 | 📋 | Astragaloside II induces osteogenic activities of osteoblasts through the bone morphogenetic protein-2/MAPK and Smad1/5/8 pathways |
| Astragalosides | Rheumatoid Arthritis | 2 | PM | 37317788 | 📋 | Astragalosides inhibit proliferation of fibroblast-like synoviocytes in experimental arthritis by modulating LncRNA S56464.1/miR-152-3p/Wnt1 signaling axis |
| Astragalosides | Rheumatoid Arthritis | 1 | PM | 34013364 | 📋 | Astragaloside regulates lncRNA LOC100912373 and the miR‑17‑5p/PDK1 axis to inhibit the proliferation of fibroblast‑like synoviocytes in rats with rheumatoid arthritis |
| Astragalosides | Rheumatoid Arthritis | 3 | PM | 31364738 | 📋 | Effect of astragalosides on long non-coding RNA expression profiles in rats with adjuvant-induced arthritis |
| Astragalosides | Spinal Cord Injury | 3 | PM | 38461631 | 📋 | Synergistic effects of tetramethylpyrazine and astragaloside IV on spinal cord injury via alteration of astrocyte A1/A2 polarization through the Sirt1-NF-κB pathway |
| Astragalosides | Spinal Cord Injury | 2 | PM | 36467371 | 📋 | Astragaloside IV ameliorates spinal cord injury through controlling ferroptosis in H2O2-damaged PC12 cells in vitro |
| Astragalosides | Spinal Cord Injury | 1 | PM | 31675186 | 📋 | Dual regulation of microglia and neurons by Astragaloside IV-mediated mTORC1 suppression promotes functional recovery after acute spinal cord injury |
