Substance | Condition | Seq | Src | PMID | Dtl | Title |
Schisandrins | Acute Lung Injury | 2 | PM | 36270224 | 📋 | Schisandrin B protects against LPS-induced inflammatory lung injury by targeting MyD88 |
Schisandrins | Airways Inflammation | 1 | PM | 34143347 | 📋 | Schisandrin B Attenuates Airway Inflammation and Airway Remodeling in Asthma by Inhibiting NLRP3 Inflammasome Activation and Reducing Pyroptosis |
Schisandrins | Allergic Asthma | 1 | PM | 35085518 | 📋 | Schisandrin B promotes Foxp3 + regulatory T cell expansion by activating heme oxygenase-1 in dendritic cells and exhibits immunomodulatory effects in Th2-mediated allergic asthma |
Schisandrins | Asthma | 3 | PM | 37329976 | 📋 | Schisandrin A ameliorates airway inflammation in model of asthma by attenuating Th2 response |
Schisandrins | Asthma | 1 | PM | 34258300 | 📋 | Schisandrin B Attenuates Airway Inflammation by Regulating the NF- κ B/Nrf2 Signaling Pathway in Mouse Models of Asthma |
Schisandrins | Asthma | 2 | PM | 34143347 | 📋 | Schisandrin B Attenuates Airway Inflammation and Airway Remodeling in Asthma by Inhibiting NLRP3 Inflammasome Activation and Reducing Pyroptosis |
Schisandrins | COPD | 2 | PM | 37400851 | 📋 | Schisandrin A regulates the Nrf2 signaling pathway and inhibits NLRP3 inflammasome activation to interfere with pyroptosis in a mouse model of COPD |
Schisandrins | COPD | 1 | PM | 32274105 | 📋 | Schisandra A Ameliorates Cigarette Smoke Extract and Lipopolysaccharide-Induced Oxidative Stress in Lung Epithelial Cells |
Schisandrins | Hypoxia | 1 | PM | 18452952 | 📋 | Schisandrin B Stereoisomers Protect Against Hypoxia/Reoxygenation-Induced Apoptosis and Inhibit Associated Changes in Ca2+-induced Mitochondrial Permeability Transition and Mitochondrial Membrane Potential in H9c2 Cardiomyocytes |
Schisandrins | Lung Cancer | 3 | PM | 38376003 | 📋 | Schizandrin A induces non-small cell lung cancer apoptosis by suppressing the epidermal growth factor receptor activation |
Schisandrins | Lung Cancer | 1 | PM | 33907830 | 📋 | Schisandrin B inhibits epithelial‑mesenchymal transition and stemness of large‑cell lung cancer cells and tumorigenesis in xenografts via inhibiting the NF‑κB and p38 MAPK signaling pathways |
Schisandrins | Lung Cancer | 2 | PM | 26221229 | 📋 | Schisandrin B Inhibits the Proliferation of Human Lung Adenocarcinoma A549 Cells by Inducing Cycle Arrest and Apoptosis |
Schisandrins | Pulmonary Fibrosis | 3 | PM | 37596361 | 📋 | Inhibitory effects of Schisandrin C on collagen behavior in pulmonary fibrosis |
Schisandrins | Pulmonary Fibrosis | 1 | PM | 31268360 | 📋 | Schisandrin B inhibits TGF-β1-induced epithelial-mesenchymal transition in human A549 cells through epigenetic silencing of ZEB1 |
Schisandrins | Pulmonary Fibrosis | 2 | PM | 28476015 | 📋 | Synergistic protection of Schizandrin B and Glycyrrhizic acid against bleomycin-induced pulmonary fibrosis by inhibiting TGF-β1/Smad2 pathways and overexpression of NOX4 |
Schisandrins | Septic Acute Lung Injury | 1 | PM | 37028276 | 📋 | Schisandrin A ameliorates increased pulmonary capillary endothelial permeability accompanied with sepsis through inhibition of RhoA/ROCK1/MLC pathways |
Schisandrins | Septic Acute Lung Injury | 2 | PM | 35313003 | 📋 | Schisandrin improves lipopolysaccharide-induced acute lung injury by inhibiting the inflammatory response in vivo and in vitro |