| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Curcumin | Abdominal Pain | 3 | PM | 33408751 | 📋 | Symptomatic uncomplicated diverticular disease management: an innovative food-grade formulation of Curcuma longa and Boswellia serrata extracts |
| Curcumin | Abdominal Pain | 4 | PM | 27308645 | 📋 | Curcumin and Fennel Essential Oil Improve Symptoms and Quality of Life in Patients With Irritable Bowel Syndrome |
| Curcumin | Abdominal Pain | 2 | PM | 19051018 | 📋 | Treatment of HIV-associated Diarrhea With Curcumin |
| Curcumin | Abdominal Pain | 1 | PM | 10495621 | 📋 | [The Effect of Chelidonium- And Turmeric Root Extract on Upper Abdominal Pain Due to Functional Disorders of the Biliary System. Results From a Placebo-Controlled Double-Blind Study] |
| Curcumin | Chronic Pain | 1 | PM | 34451874 | 📋 | Mechanistic Insight into the Effects of Curcumin on Neuroinflammation-Driven Chronic Pain |
| Curcumin | Chronic Prostatitis | 4 | PM | 34914324 | 📋 | [Lycopene combined with quercetin and curcumin for chronic prostatitis/chronic pelvic pain syndrome in rats: Effect and mechanism] |
| Curcumin | Chronic Prostatitis | 3 | PM | 28679180 | 📋 | A phase II, randomized, single-blinded, placebo-controlled clinical trial on the efficacy of Curcumina and Calendula suppositories for the treatment of patients with chronic prostatitis/chronic pelvic pain syndrome type III |
| Curcumin | Chronic Prostatitis | 2 | PM | 20180411 | 📋 | [Reducing Effect of Curcumin on Expressions of TNF-alpha, IL-6 and IL-8 in Rats With Chronic Nonbacterial Prostatitis] |
| Curcumin | Chronic Prostatitis | 1 | PM | 19181486 | 📋 | Serenoa Repens Associated With Urtica Dioica (ProstaMEV) and Curcumin and Quercitin (FlogMEV) Extracts Are Able to Improve the Efficacy of Prulifloxacin in Bacterial Prostatitis Patients: Results From a Prospective Randomised Study |
| Curcumin | Dysmenorrhea | 1 | PM | 38266637 | 📋 | Effect of Curcumin on Dysmenorrhea and Symptoms of Premenstrual Syndrome: A Systematic Review and Meta-Analysis |
| Curcumin | Hyperalgesia | 4 | PM | 26744842 | 📋 | PLGA-Curcumin Attenuates Opioid-Induced Hyperalgesia and Inhibits Spinal CaMKIIα |
| Curcumin | Hyperalgesia | 3 | PM | 25479948 | 📋 | Curcumin Attenuates CFA Induced Thermal Hyperalgesia by Modulation of Antioxidant Enzymes and Down Regulation of TNF-α, IL-1β and IL-6 |
| Curcumin | Hyperalgesia | 2 | PM | 20040737 | 📋 | Curcumin Produces an Antihyperalgesic Effect via Antagonism of TRPV1 |
| Curcumin | Hyperalgesia | 1 | PM | 16584726 | 📋 | Curcumin Attenuates Thermal Hyperalgesia in a Diabetic Mouse Model of Neuropathic Pain |
| Curcumin | Knee Pain | 2 | PM | 35010916 | 📋 | An Investigation into the Effects of a Curcumin Extract (Curcugen ®) on Osteoarthritis Pain of the Knee: A Randomised, Double-Blind, Placebo-Controlled Study |
| Curcumin | Knee Pain | 1 | PM | 33032585 | 📋 | The effect of curcumin ointment on knee pain in older adults with osteoarthritis: a randomized placebo trial |
| Curcumin | Mastalgia | 1 | PM | 31673442 | 📋 | Effective Medicinal Plants in the Treatment of the Cyclic Mastalgia (Breast Pain): A Review |
| Curcumin | Migraine | 6 | PM | 37216708 | 📋 | The impact of curcumin on migraine: A comprehensive review |
| Curcumin | Migraine | 5 | PM | 35070194 | 📋 | Effects of Curcumin Supplementation on Clinical Features and Inflammation, in Migraine Patients: A Double-Blind Controlled, Placebo Randomized Clinical Trial |
| Curcumin | Migraine | 4 | PM | 32727335 | 📋 | Anti-Neuroinflammatory Properties of n-3 Fatty Acids and Nano-Curcumin on Migraine Patients, from Cellular to Clinical Insight: A Randomized, Double Blind, and Placebo-Controlled Trial |
| Curcumin | Migraine | 2 | PM | 31287810 | 📋 | Liposomal Curcumin Enhances the Effect of Naproxen in a Rat Model of Migraine |
| Curcumin | Migraine | 3 | PM | 31241007 | 📋 | The Synergistic Effects of Nano-Curcumin and Coenzyme Q10 Supplementation in Migraine Prophylaxis: A Randomized, Placebo-Controlled, Double-Blind Trial |
| Curcumin | Migraine | 1 | PM | 28478481 | 📋 | The Synergistic Effects of ω-3 Fatty Acids and Nano-Curcumin Supplementation on Tumor Necrosis Factor (TNF)-α Gene Expression and Serum Level in Migraine Patients |
| Curcumin | Neuropathic Pain | 9 | PM | 37892476 | 📋 | Turmeric Bioactive Compounds Alleviate Spinal Nerve Ligation-Induced Neuropathic Pain by Suppressing Glial Activation and Improving Mitochondrial Function in Spinal Cord and Amygdala |
| Curcumin | Neuropathic Pain | 8 | PM | 36931068 | 📋 | Curcumin promotes microglial M2 polarization and suppresses chronic constriction: Injury-induced neuropathic pain in a rat model of peripheral neuropathy |
| Curcumin | Neuropathic Pain | 4 | PM | 36567422 | 📋 | Involvement of TRPM7 Channel on the Induction of Diabetic Neuropathic Pain in Mice: Protective Role of Selenium and Curcumin |
| Curcumin | Neuropathic Pain | 2 | PM | 35763932 | 📋 | Computational approach to decode the mechanism of curcuminoids against neuropathic pain |
| Curcumin | Neuropathic Pain | 7 | PM | 33925121 | 📋 | Effects of Curcumin and Its Different Formulations in Preclinical and Clinical Studies of Peripheral Neuropathic and Postoperative Pain: A Comprehensive Review |
| Curcumin | Neuropathic Pain | 6 | PM | 33907454 | 📋 | Curcumin Alleviates Chronic Pain and Improves Cognitive Impairment via Enhancing Hippocampal Neurogenesis in Sciatic Nerve Constriction Rats |
| Curcumin | Neuropathic Pain | 5 | PM | 27381056 | 📋 | Curcumin Ameliorates Neuropathic Pain by Down-Regulating Spinal IL-1β via Suppressing Astroglial NALP1 Inflammasome and JAK2-STAT3 Signalling |
| Curcumin | Neuropathic Pain | 1 | PM | 24297305 | 📋 | Chronic Curcumin Treatment Normalizes Depression-Like Behaviors in Mice With Mononeuropathy: Involvement of Supraspinal Serotonergic System and GABAA Receptor |
| Curcumin | Neuropathic Pain | 3 | PM | 21945716 | 📋 | Curcumin Exerts Antinociceptive Effects in a Mouse Model of Neuropathic Pain: Descending Monoamine System and Opioid Receptors Are Differentially Involved |
| Curcumin | Orofacial Pain | 4 | PM | 37632838 | 📋 | Curcumin alleviates orofacial allodynia and improves cognitive impairment via regulating hippocampal synaptic plasticity in a mouse model of trigeminal neuralgia |
| Curcumin | Orofacial Pain | 3 | PM | 36096139 | 📋 | The Efficacy of Curcumin Patch as an Adjuvant Therapeutic Agent in Managing Acute Orofacial Pain on the Post-Cleft Lip and Cleft Palate Surgery Patients: A Pragmatic Trial |
| Curcumin | Orofacial Pain | 2 | PM | 35682028 | 📋 | Effectiveness of Curcumin in Reducing Self-Rated Pain-Levels in the Orofacial Region: A Systematic Review of Randomized-Controlled Trials |
| Curcumin | Orofacial Pain | 1 | PM | 19051211 | 📋 | Evaluation of Antihyperalgesic Effect of Curcumin on Formalin-Induced Orofacial Pain in Rat |
| Curcumin | Pain | 16 | PM | 36274168 | 📋 | Combination of curcumin and piperine synergistically improves pain-like behaviors in mouse models of pain with no potential CNS side effects |
| Curcumin | Pain | 15 | PM | 35690654 | 📋 | Curcumin and metformin synergistically modulate peripheral and central immune mechanisms of pain |
| Curcumin | Pain | 3 | PM | 35032552 | 📋 | Curcumin induces peripheral antinociception by opioidergic and cannabinoidergic mechanism: Pharmacological evidence |
| Curcumin | Pain | 14 | PM | 34539332 | 📋 | Curcumin Exerts Antinociceptive Effects in Cancer-Induced Bone Pain via an Endogenous Opioid Mechanism |
| Curcumin | Pain | 13 | PM | 34312922 | 📋 | A review of therapeutic potentials of turmeric (Curcuma longa) and its active constituent, curcumin, on inflammatory disorders, pain, and their related patents |
| Curcumin | Pain | 12 | PM | 33925121 | 📋 | Effects of Curcumin and Its Different Formulations in Preclinical and Clinical Studies of Peripheral Neuropathic and Postoperative Pain: A Comprehensive Review |
| Curcumin | Pain | 10 | PM | 32981501 | 📋 | Curcumin and its Multi-target Function Against Pain and Inflammation: An Update of Pre-clinical Data |
| Curcumin | Pain | 9 | PM | 32664057 | 📋 | Efficacy of high-dissolution turmeric-sesame formulation for pain relief in adult subjects with acute musculoskeletal pain compared to acetaminophen: A randomized controlled study |
| Curcumin | Pain | 5 | PM | 32387235 | 📋 | Anti-inflammatory and Antinociceptive Effects of Curcuma Kwangsiensis and Its Bioactive Terpenoids in Vivo and in Vitro |
| Curcumin | Pain | 7 | PM | 30466988 | 📋 | Curcumin Downregulates Expression of Opioid-Related Nociceptin Receptor Gene (OPRL1) in Isolated Neuroglia Cells |
| Curcumin | Pain | 8 | PM | 30195871 | 📋 | Role of Curcumin in the Management of Pathological Pain |
| Curcumin | Pain | 1 | PM | 25352926 | 📋 | A New Curcuma Extract (Flexofytol®) in Osteoarthritis: Results From a Belgian Real-Life Experience |
| Curcumin | Pain | 2 | PM | 23091682 | 📋 | Evidence for the Participation of ATP-sensitive Potassium Channels in the Antinociceptive Effect of Curcumin |
| Curcumin | Pain | 6 | PM | 19070135 | 📋 | Interaction Between Curcumin and Opioid System in the Formalin Test of Rats |
| Curcumin | Pain | 4 | PM | 18817212 | 📋 | The Effect of Curcumin (Active Substance of Turmeric) on the Acetic Acid-Induced Visceral Nociception in Rats |
| Curcumin | Peripheral Neuropathy | 10 | PM | 33925121 | 📋 | Effects of Curcumin and Its Different Formulations in Preclinical and Clinical Studies of Peripheral Neuropathic and Postoperative Pain: A Comprehensive Review |
| Curcumin | Peripheral Neuropathy | 6 | PM | 33023197 | 📋 | Key Developments in the Potential of Curcumin for the Treatment of Peripheral Neuropathies |
| Curcumin | Peripheral Neuropathy | 7 | PM | 27215022 | 📋 | Effects of Curcumin on Sodium Currents of Dorsal Root Ganglion Neurons in Type 2 Diabetic Neuropathic Pain Rats |
| Curcumin | Peripheral Neuropathy | 8 | PM | 26282904 | 📋 | Effects of Curcumin on TTX-R Sodium Currents of Dorsal Root Ganglion Neurons in Type 2 Diabetic Rats With Diabetic Neuropathic Pain |
| Curcumin | Peripheral Neuropathy | 2 | PM | 26113793 | 📋 | Curcumin Ameliorates Functional and Structural Abnormalities in Cisplatin-induced Neuropathy |
| Curcumin | Peripheral Neuropathy | 9 | PM | 24315931 | 📋 | Effect of Curcumin on Diabetic Peripheral Neuropathic Pain: Possible Involvement of Opioid System |
| Curcumin | Peripheral Neuropathy | 1 | PM | 23250879 | 📋 | Curcumin Derivatives Promote Schwann Cell Differentiation and Improve Neuropathy in R98C CMT1B Mice |
| Curcumin | Peripheral Neuropathy | 3 | PM | 22281447 | 📋 | Therapeutic Role of Curcumin in Prevention of Biochemical and Behavioral Aberration Induced by Alcoholic Neuropathy in Laboratory Animals |
| Curcumin | Peripheral Neuropathy | 5 | PM | 17701891 | 📋 | Oral Curcumin Mitigates the Clinical and Neuropathologic Phenotype of the Trembler-J Mouse: A Potential Therapy for Inherited Neuropathy |
| Curcumin | Peripheral Neuropathy | 4 | PM | 16252242 | 📋 | Curcumin Treatment Abrogates Endoplasmic Reticulum Retention and Aggregation-Induced Apoptosis Associated With Neuropathy-Causing Myelin Protein Zero-Truncating Mutants |
| Curcumin | Sciatica | 3 | PM | 33201400 | 📋 | Protective Effects of Curcumin Against Paclitaxel-Induced Spinal Cord and Sciatic Nerve Injuries in Rats |
| Curcumin | Sciatica | 1 | PM | 31611748 | 📋 | Comparison of Melatonin and Curcumin Effect at the Light and Dark Periods on Regeneration of Sciatic Nerve Crush Injury in Rats |
| Curcumin | Sciatica | 2 | PM | 24317243 | 📋 | An Experimental Comparison of the Effects of Propolis, Curcumin, and Methylprednisolone on Crush Injuries of the Sciatic Nerve |
| Curcumin | Trigeminal Neuralgia | 2 | PM | 37632838 | 📋 | Curcumin alleviates orofacial allodynia and improves cognitive impairment via regulating hippocampal synaptic plasticity in a mouse model of trigeminal neuralgia |
| Curcumin | Trigeminal Neuralgia | 1 | PM | 33402844 | 📋 | Curcumin Improves Chronic Pain Induced Depression Through Regulating Serum Metabolomics in a Rat Model of Trigeminal Neuralgia |
