| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Hesperidin | Alzheimer's Disease | 8 | PM | 37913913 | 📋 | Hesperidin ameliorates Amyloid-β toxicity and enhances oxidative stress resistance and lifespan of Caenorhabditis elegans through acr-16 mediated activation of the autophagy pathway |
| Hesperidin | Alzheimer's Disease | 7 | PM | 37895841 | 📋 | Dapagliflozin/Hesperidin Combination Mitigates Lipopolysaccharide-Induced Alzheimer's Disease in Rats |
| Hesperidin | Alzheimer's Disease | 4 | PM | 35956303 | 📋 | Hesperidin Improves Memory Function by Enhancing Neurogenesis in a Mouse Model of Alzheimer's Disease |
| Hesperidin | Alzheimer's Disease | 1 | PM | 35776430 | 📋 | Neuroprotective Effects of Hesperidin and Naringin in SK-N-AS Cell as an In Vitro Model for Alzheimer's Disease |
| Hesperidin | Alzheimer's Disease | 3 | PM | 34170456 | 📋 | Histological and imunohistochemical alterations of hippocampus and prefrontal cortex in a rat model of Alzheimer like-disease with a preferential role of the flavonoid "hesperidin" |
| Hesperidin | Alzheimer's Disease | 2 | PM | 29687202 | 📋 | Attenuation of Aluminum Chloride-Induced Neuroinflammation and Caspase Activation Through the AKT/GSK-3β Pathway by Hesperidin in Wistar Rats |
| Hesperidin | Alzheimer's Disease | 6 | PM | 26391026 | 📋 | Hesperidin attenuates learning and memory deficits in APP/PS1 mice through activation of Akt/Nrf2 signaling and inhibition of RAGE/NF-κB signaling |
| Hesperidin | Alzheimer's Disease | 5 | PM | 23475456 | 📋 | Protective effects of hesperidin against amyloid-β (Aβ) induced neurotoxicity through the voltage dependent anion channel 1 (VDAC1)-mediated mitochondrial apoptotic pathway in PC12 cells |
| Hesperidin | Amyotrophic Lateral Sclerosis | 1 | PM | 24963318 | 📋 | Finding inhibitors of mutant superoxide dismutase-1 for amyotrophic lateral sclerosis therapy from traditional chinese medicine |
| Hesperidin | Huntington's Disease | 1 | PM | 24211676 | 📋 | Minocycline modulates neuroprotective effect of hesperidin against quinolinic acid induced Huntington's disease like symptoms in rats: behavioral, biochemical, cellular and histological evidences |
| Hesperidin | Multiple Sclerosis | 2 | PM | 38154346 | 📋 | The protective effects of hesperidin as an antioxidant against quinolinic acid-induced toxicity on oligodendroglia cells: An in vitro study |
| Hesperidin | Multiple Sclerosis | 1 | PM | 27912911 | 📋 | Hesperidin ameliorates immunological outcome and reduces neuroinflammation in the mouse model of multiple sclerosis |
| Hesperidin | Neurodegenerative Disease | 2 | PM | 36959141 | 📋 | Neuroprotective Potential of Hesperidin as Therapeutic Agent in the Treatment of Brain Disorders: Preclinical Evidence-based Review |
| Hesperidin | Neurodegenerative Disease | 1 | PM | 35379141 | 📋 | Therapeutic Potential and Clinical Evidence of Hesperidin as Neuroprotective Agent |
| Hesperidin | Neurodegenerative Disease | 5 | PM | 34987244 | 📋 | Therapeutic potential of hesperidin in Parkinson's disease with dementia: inhibition of alpha synuclein and amyloid beta in Drosophila melanogaster |
| Hesperidin | Neurodegenerative Disease | 3 | PM | 26878879 | 📋 | Hesperidin ameliorates cognitive dysfunction, oxidative stress and apoptosis against aluminium chloride induced rat model of Alzheimer's disease |
| Hesperidin | Parkinson's Disease | 7 | PM | 38423185 | 📋 | Antioxidant responses driven by Hesperetin and Hesperidin counteract Parkinson's disease-like phenotypes in Drosophila melanogaster |
| Hesperidin | Parkinson's Disease | 6 | PM | 35167856 | 📋 | Improvement of non-motor and motor behavioral alterations associated with Parkinson-like disease in Drosophila melanogaster: comparative effects of treatments with hesperidin and L-dopa |
| Hesperidin | Parkinson's Disease | 4 | PM | 33075420 | 📋 | Hesperidin downregulates kinases lrrk2 and gsk3β in a 6-OHDA induced Parkinson's disease model |
| Hesperidin | Parkinson's Disease | 5 | PM | 33057922 | 📋 | Hesperidin protects against behavioral alterations and loss of dopaminergic neurons in 6-OHDA-lesioned mice: the role of mitochondrial dysfunction and apoptosis |
| Hesperidin | Parkinson's Disease | 3 | PM | 32918805 | 📋 | 6-OHDA mediated neurotoxicity in SH-SY5Y cellular model of Parkinson disease suppressed by pretreatment with hesperidin through activating L-type calcium channels |
| Hesperidin | Parkinson's Disease | 1 | PM | 32458386 | 📋 | Hesperidin Ameliorates Anxiety-Depressive-Like Behavior in 6-OHDA Model of Parkinson's Disease by Regulating Striatal Cytokine and Neurotrophic Factors Levels and Dopaminergic Innervation Loss in the Striatum of Mice |
| Hesperidin | Parkinson's Disease | 2 | PM | 29191452 | 📋 | Hesperidin attenuates iron-induced oxidative damage and dopamine depletion in Drosophila melanogaster model of Parkinson's disease |
