| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| St. Johns Wort | Age-Related Cognitive Decline | 1 | PM | 20361314 | 📋 | Activation of CREB by St. John's Wort May Diminish Deletorious Effects of Aging on Spatial Memory |
| St. Johns Wort | Alzheimer's Disease | 3 | PM | 38279301 | 📋 | Apolar Extracts of St. John's Wort Alleviate the Effects of β-Amyloid Toxicity in Early Alzheimer's Disease |
| St. Johns Wort | Alzheimer's Disease | 2 | PM | 34567498 | 📋 | Unprecedented polycyclic polyprenylated acylphloroglucinols with anti-Alzheimer's activity from St. John's wort |
| St. Johns Wort | Alzheimer's Disease | 1 | PM | 28514831 | 📋 | Hypericum Perforatum Extract Attenuates Behavioral, Biochemical, and Neurochemical Abnormalities in Aluminum Chloride-Induced Alzheimer's Disease Rats |
| St. Johns Wort | Brain Inflammation | 1 | PM | 26119304 | 📋 | Hypericum Perforatum Hydroalcoholic Extract Mitigates Motor Dysfunction and Is Neuroprotective in Intrastriatal 6-Hydroxydopamine Rat Model of Parkinson's Disease |
| St. Johns Wort | Depression | 14 | PM | 38684848 | 📋 | St. John's wort extract Ze 117 alters the membrane fluidity of C6 glioma cells by influencing cellular cholesterol metabolism |
| St. Johns Wort | Depression | 13 | PM | 37663381 | 📋 | The antidepressant effect of combined extracts of Hypericum perforatum and Echium amoenum supplementation in patients with depression symptoms: A randomized clinical trial |
| St. Johns Wort | Depression | 12 | PM | 37029349 | 📋 | Impact of St. John's wort extract Ze 117 on stress induced changes in the lipidome of PBMC |
| St. Johns Wort | Depression | 11 | PM | 36299970 | 📋 | Advantages and Disadvantages of Using St. John's Wort as a Treatment for Depression |
| St. Johns Wort | Depression | 10 | PM | 35294606 | 📋 | St. John's wort (Hypericum perforatum) and depression: what happens to the neurotransmitter systems? |
| St. Johns Wort | Depression | 9 | PM | 33628177 | 📋 | In Vitro Effects of St. John's Wort Extract Against Inflammatory and Oxidative Stress and in the Phagocytic and Migratory Activity of Mouse SIM-A9 Microglia |
| St. Johns Wort | Depression | 3 | PM | 30484733 | 📋 | Subchronic Treatment With St John's Wort Produces a Positive Shift in Emotional Processing in Healthy Volunteers |
| St. Johns Wort | Depression | 7 | PM | 30461013 | 📋 | Hypericum Perforatum in the Treatment of Psychiatric and Neurodegenerative Disorders: Current Evidence and Potential Mechanisms of Action |
| St. Johns Wort | Depression | 2 | PM | 29991209 | 📋 | Role in Depression of a Multi-Fractionated Versus a Conventional Hypericum Perforatum Extract |
| St. Johns Wort | Depression | 4 | PM | 29499586 | 📋 | Hyperforin and Miquelianin From St. John's Wort Attenuate Gene Expression in Neuronal Cells After Dexamethasone-Induced Stress |
| St. Johns Wort | Depression | 1 | PM | 28064110 | 📋 | Clinical Use of Hypericum Perforatum (St John's Wort) in Depression: A Meta-Analysis |
| St. Johns Wort | Depression | 5 | PM | 19028540 | 📋 | Efficacy and Tolerability of Hypericum Perforatum in Major Depressive Disorder in Comparison With Selective Serotonin Reuptake Inhibitors: A Meta-Analysis |
| St. Johns Wort | Depression | 8 | PM | 14659982 | 📋 | Sub-chronic treatment with an extract of Hypericum perforatum (St John's wort) significantly reduces cortisol and corticosterone in the rat brain |
| St. Johns Wort | Depression | 6 | PM | 11819157 | 📋 | St. John's Wort (Hypericum Perforatum)--Is It Safe During Breastfeeding? |
| St. Johns Wort | Diabetic Neuropathy | 1 | PM | 24125916 | 📋 | St. John's Wort Seed and Feverfew Flower Extracts Relieve Painful Diabetic Neuropathy in a Rat Model of Diabetes |
| St. Johns Wort | Glioblastoma | 2 | PM | 32485087 | 📋 | Hyperforin induces apoptosis through extrinsic/intrinsic pathways and inhibits EGFR/ERK/NF-κB-mediated anti-apoptotic potential in glioblastoma |
| St. Johns Wort | HIV/AIDS | 1 | PM | 19594941 | 📋 | Identification of Light-Independent Inhibition of Human Immunodeficiency virus-1 Infection Through Bioguided Fractionation of Hypericum Perforatum |
| St. Johns Wort | HIV/AIDS | 2 | PM | 18378326 | 📋 | Creation of a Bi-Directional Protein Transduction System for Suppression of HIV-1 Expression by p27SJ |
| St. Johns Wort | HIV/AIDS | 3 | PM | 16251997 | 📋 | p27(SJ), a Novel Protein in St John's Wort, That Suppresses Expression of HIV-1 Genome |
| St. Johns Wort | HIV/AIDS | 4 | PM | 12665247 | 📋 | Mood-enhancing Antidepressant St. John's Wort Inhibits the Activation of Human Immunodeficiency Virus Gene Expression by Ultraviolet Light |
| St. Johns Wort | Multiple Sclerosis | 2 | PM | 26634391 | 📋 | St. John's Wort and Its Component Hyperforin Alleviate Experimental Autoimmune Encephalomyelitis Through Expansion of Regulatory T-cells |
| St. Johns Wort | Multiple Sclerosis | 1 | PM | 18570265 | 📋 | An Iranian Herbal-Marine Medicine, MS14, Ameliorates Experimental Allergic Encephalomyelitis |
| St. Johns Wort | Orofacial Pain | 1 | PM | 28137525 | 📋 | Hypericum Perforatum (St. John's Wort) as a Possible Therapeutic Alternative for the Management of Trigeminal Neuralgia (TN) - A Case Report |
| St. Johns Wort | Pain | 2 | PM | 28216196 | 📋 | Hypericum Perforatum (St John's Wort) Beyond Depression: A Therapeutic Perspective for Pain Conditions |
| St. Johns Wort | Pain | 1 | PM | 16414593 | 📋 | Antinociceptive Activity of Methanolic Extracts of St. John's Wort (Hypericum Perforatum) Preparation |
| St. Johns Wort | Parkinson's Disease | 1 | PM | 26119304 | 📋 | Hypericum Perforatum Hydroalcoholic Extract Mitigates Motor Dysfunction and Is Neuroprotective in Intrastriatal 6-Hydroxydopamine Rat Model of Parkinson's Disease |
| St. Johns Wort | Sciatic Nerve Injury | 1 | PM | 28508406 | 📋 | Hypericum Perforatum L. Supplementation Protects Sciatic Nerve Injury-Induced Apoptotic, Inflammatory and Oxidative Damage to Muscle, Blood and Brain in Rats |
| St. Johns Wort | Stroke | 1 | PM | 27328426 | 📋 | Hyperforin Promotes Post-Stroke Functional Recovery Through Interleukin (IL)-17A-mediated Angiogenesis |
| St. Johns Wort | Trigeminal Neuralgia | 1 | PM | 28137525 | 📋 | Hypericum Perforatum (St. John's Wort) as a Possible Therapeutic Alternative for the Management of Trigeminal Neuralgia (TN) - A Case Report |
