| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Spirulina | Age-Related Cognitive Decline | 1 | PM | 25821309 | 📋 | Combination of Spirulina with glycyrrhizin prevents cognitive dysfunction in aged obese rats |
| Spirulina | Alzheimer's Disease | 3 | PM | 36861852 | 📋 | The effects of spirulina intake on clinical and metabolic parameters in Alzheimer's disease: A randomized, double-blind, controlled trial |
| Spirulina | Alzheimer's Disease | 2 | PM | 29499310 | 📋 | Spirulina maxima extract prevents cell death through BDNF activation against amyloid beta 1-42 (Aβ 1-42) induced neurotoxicity in PC12 cells |
| Spirulina | Alzheimer's Disease | 1 | PM | 29137190 | 📋 | Spirulina maxima Extract Ameliorates Learning and Memory Impairments via Inhibiting GSK-3β Phosphorylation Induced by Intracerebroventricular Injection of Amyloid-β 1-42 in Mice |
| Spirulina | Brain Inflammation | 1 | PM | 27571388 | 📋 | Spirulina diet to lactating mothers protects the antioxidant system and reduces inflammation in post-natal brain after systemic inflammation |
| Spirulina | Chronic Stress | 1 | PM | 32256126 | 📋 | Therapeutic Effects of Spirulina platensis Against Adolescent Stress-Induced Oxidative Stress, Brain-Derived Neurotrophic Factor Alterations and Morphological Remodeling in the Amygdala of Adult Female Rats |
| Spirulina | Dementia | 1 | PM | 30598686 | 📋 | Effect of Fermented Spirulina maxima Extract on Cognitive-Enhancing Activities in Mice with Scopolamine-Induced Dementia |
| Spirulina | Diabetic Neuropathy | 1 | PM | 32982392 | 📋 | Oral Spirulina Platensis Attenuates Hyperglycemia and Exhibits Antinociceptive Effect in Streptozotocin-Induced Diabetic Neuropathy Rat Model |
| Spirulina | Glioblastoma | 1 | PM | 34606108 | 📋 | Chemopreventive effect of spirulina microalgae on an animal model of glioblastoma via down-regulation of PI3K/AKT/mTOR and up-regulation of miR-34a/miR-125B expression |
| Spirulina | HIV/AIDS | 1 | PM | 26195001 | 📋 | Impact of daily supplementation of Spirulina platensis on the immune system of naïve HIV-1 patients in Cameroon: a 12-months single blind, randomized, multicenter trial |
| Spirulina | HIV/AIDS | 2 | PM | 22254118 | 📋 | The effect of Spirulina platensis versus soybean on insulin resistance in HIV-infected patients: a randomized pilot study |
| Spirulina | Neurodegenerative Disease | 2 | PM | 35834631 | 📋 | The Protein-Rich Fraction from Spirulina platensis Exerts Neuroprotection in Hemiparkinsonian Rats by Decreasing Brain Inflammatory-Related Enzymes and Glial Fibrillary Acidic Protein Expressions |
| Spirulina | Neurodegenerative Disease | 1 | PM | 35277035 | 📋 | Beneficial Effects of Spirulina Consumption on Brain Health |
| Spirulina | Neuroinflammation | 3 | PM | 36422287 | 📋 | Spirulina platensis Suppressed iNOS and Proinflammatory Cytokines in Lipopolysaccharide-Induced BV2 Microglia |
| Spirulina | Neuroinflammation | 2 | PM | 34566649 | 📋 | Pre- and Early Post-treatment With Arthrospira platensis (Spirulina) Extract Impedes Lipopolysaccharide-triggered Neuroinflammation in Microglia |
| Spirulina | Neuroinflammation | 1 | PM | 20463965 | 📋 | Spirulina promotes stem cell genesis and protects against LPS induced declines in neural stem cell proliferation |
| Spirulina | Neurological Disorders | 1 | PM | 37602106 | 📋 | Exploring the Neuroprotective Effects of Spirulina platensis: Insights Into Hemorrhagic Volume and Histological Outcomes |
| Spirulina | Neurotoxicity | 2 | PM | 37773524 | 📋 | Antioxidant and anti-inflammatory potential of spirulina and thymoquinone mitigate the methotrexate-induced neurotoxicity |
| Spirulina | Neurotoxicity | 1 | PM | 29720839 | 📋 | Protective Effect of Water Extracted Spirulina maxima on Glutamate-induced Neuronal Cell Death in Mouse Hippocampal HT22 Cell |
| Spirulina | Pain | 2 | PM | 33824110 | 📋 | Effects of Spirulina platensis on pain and inflammation in long Evans rats |
| Spirulina | Pain | 1 | PM | 31126833 | 📋 | Spirulina consumption effectively reduces anti-inflammatory and pain related infectious diseases |
| Spirulina | Parkinson's Disease | 2 | PM | 26306668 | 📋 | Neuroprotective effect of Spirulina fusiform and amantadine in the 6-OHDA induced Parkinsonism in rats |
| Spirulina | Parkinson's Disease | 1 | PM | 25883632 | 📋 | Protective effects of a polysaccharide from Spirulina platensis on dopaminergic neurons in an MPTP-induced Parkinson's disease model in C57BL/6J mice |
| Spirulina | Schizophrenia | 2 | PM | 33794248 | 📋 | Spirulina platensis reduces the schizophrenic-like symptoms in rat model by restoring altered APO-E and RTN-4 protein expression in prefrontal cortex |
| Spirulina | Schizophrenia | 1 | PM | 33612469 | 📋 | Spirulina platensis (Blue-green algae): A miracle from sea combats the oxidative stress and improves behavioral deficits in an animal model of Schizophrenia |
| Spirulina | Spinal Cord Injury | 1 | PM | 32686973 | 📋 | Improved spinal cord gray matter morphology induced by Spirulina platensis following spinal cord injury in rat models |
| Spirulina | Spinal Cord Injury | 2 | PM | 31779507 | 📋 | Neuroprotective potential of Spirulina platensis on lesioned spinal cord corticospinal tract under experimental conditions in rat models |
| Spirulina | Stress | 1 | PM | 36330789 | 📋 | Dietary intake of Spirulina platensis alters HSP70 gene expression profiles in the brain of rats in an experimental model of mixed stress |
| Spirulina | Tinnitus | 2 | PM | 29993223 | 📋 | Effects of Spirulina on GABA Receptor Gene Expression in Salicylate-Induced Tinnitus |
| Spirulina | Tinnitus | 1 | PM | 26277928 | 📋 | Expression of Antioxidant Genes in the Mouse Cochlea and Brain in Salicylate-Induced Tinnitus and Effect of Treatment with Spirulina platensis Water Extract |
