| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Shogaol | Depression | 1 | PM | 35036685 | 📋 | 6-Shogaol Attenuates Traumatic Brain Injury-Induced Anxiety/Depression-like Behavior via Inhibition of Oxidative Stress-Influenced Expressions of Inflammatory Mediators TNF-α, IL-1β, and BDNF: Insight into the Mechanism |
| Shogaol | Diabetic Neuropathy | 1 | PM | 31743763 | 📋 | Ginger extract and its compound, 6-shogaol, attenuates painful diabetic neuropathy in mice via reducing TRPV1 and NMDAR2B expressions in the spinal cord |
| Shogaol | Intracerebral Hemorrhage | 1 | PM | 30365933 | 📋 | Shogaol but not gingerol has a neuroprotective effect on hemorrhagic brain injury: Contribution of the α, β-unsaturated carbonyl to heme oxygenase-1 expression |
| Shogaol | Neuroinflammation | 2 | PM | 36873986 | 📋 | Natural product-based bioactive agents in combination attenuate neuroinflammation in a tri-culture model |
| Shogaol | Neuroinflammation | 1 | PM | 36173059 | 📋 | Neuroprotective effects of Shogaol in metals (Al, As and Pb) and high fat diet induced neuroinflammation and behavior in mice |
| Shogaol | Neuroinflammation | 3 | PM | 22465818 | 📋 | 6-Shogaol, a ginger product, modulates neuroinflammation: a new approach to neuroprotection |
| Shogaol | Neuropathic Pain | 2 | PM | 38813490 | 📋 | [6]-Shogaol and [6]-Gingerol active ingredients may improve neuropathic pain by suppressing cytokine levels in an experimental model |
| Shogaol | Neuropathic Pain | 1 | PM | 35745645 | 📋 | [6]-Shogaol Attenuates Oxaliplatin-Induced Allodynia through Serotonergic Receptors and GABA in the Spinal Cord in Mice |
| Shogaol | Pain | 1 | PM | 36079679 | 📋 | The Effect of Ginger and Its Sub-Components on Pain |
| Shogaol | Parkinson's Disease | 1 | PM | 37337830 | 📋 | 6-Shogaol, an Active Ingredient of Ginger, Improves Intestinal and Brain Abnormalities in Proteus Mirabilis-Induced Parkinson's Disease Mouse Model |
| Shogaol | Rheumatoid Arthritis | 2 | PM | 36610124 | 📋 | 6-Shogaol inhibits the proliferation, apoptosis, and migration of rheumatoid arthritis fibroblast-like synoviocytes via the PI3K/AKT/NF-κB pathway |
| Shogaol | Rheumatoid Arthritis | 1 | PM | 35283302 | 📋 | 8-Shogaol Inhibits Rheumatoid Arthritis through Targeting TAK1 |
| Shogaol | Traumatic Brain Injury | 1 | PM | 35036685 | 📋 | 6-Shogaol Attenuates Traumatic Brain Injury-Induced Anxiety/Depression-like Behavior via Inhibition of Oxidative Stress-Influenced Expressions of Inflammatory Mediators TNF-α, IL-1β, and BDNF: Insight into the Mechanism |
