| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Salidroside | Age-Related Cognitive Decline | 1 | PM | 25520005 | 📋 | Therapeutic Intervention of Learning and Memory Decays by Salidroside Stimulation of Neurogenesis in Aging |
| Salidroside | Alzheimer's Disease | 4 | PM | 36965372 | 📋 | Salidroside alleviates cognitive impairment by inhibiting ferroptosis via activation of the Nrf2/GPX4 axis in SAMP8 mice |
| Salidroside | Alzheimer's Disease | 3 | PM | 36333711 | 📋 | Salidroside reduces neuropathology in Alzheimer's disease models by targeting NRF2/SIRT3 pathway |
| Salidroside | Alzheimer's Disease | 2 | PM | 35787281 | 📋 | Salidroside attenuates neuronal ferroptosis by activating the Nrf2/HO1 signaling pathway in Aβ 1-42-induced Alzheimer's disease mice and glutamate-injured HT22 cells |
| Salidroside | Alzheimer's Disease | 1 | PM | 35126093 | 📋 | Salidroside Ameliorates Alzheimer's Disease by Targeting NLRP3 Inflammasome-Mediated Pyroptosis |
| Salidroside | Alzheimer's Disease | 15 | PM | 33362539 | 📋 | Salidroside Attenuates Cognitive Dysfunction in Senescence-Accelerated Mouse Prone 8 (SAMP8) Mice and Modulates Inflammation of the Gut-Brain Axis |
| Salidroside | Alzheimer's Disease | 14 | PM | 32002777 | 📋 | Neuroprotective Effects of Salidroside in a Mouse Model of Alzheimer's Disease |
| Salidroside | Alzheimer's Disease | 6 | PM | 30720058 | 📋 | Salidroside protects PC-12 cells against amyloid β-induced apoptosis by activation of the ERK1/2 and AKT signaling pathways |
| Salidroside | Alzheimer's Disease | 10 | PM | 28714019 | 📋 | Salidroside protects PC12 cells from Aβ1‑40‑induced cytotoxicity by regulating the nicotinamide phosphoribosyltransferase signaling pathway |
| Salidroside | Alzheimer's Disease | 12 | PM | 27933142 | 📋 | Salidroside reduces tau hyperphosphorylation via up-regulating GSK-3β phosphorylation in a tau transgenic Drosophila model of Alzheimer's disease |
| Salidroside | Alzheimer's Disease | 8 | PM | 27103787 | 📋 | Neuroprotective effects of salidroside through PI3K/Akt pathway activation in Alzheimer's disease models |
| Salidroside | Alzheimer's Disease | 13 | PM | 26909502 | 📋 | Salidroside suppresses inflammation in a D-galactose-induced rat model of Alzheimer's disease via SIRT1/NF-κB pathway |
| Salidroside | Alzheimer's Disease | 11 | PM | 26192909 | 📋 | Salidroside ameliorates cognitive impairment in a d-galactose-induced rat model of Alzheimer's disease |
| Salidroside | Alzheimer's Disease | 5 | PM | 23396166 | 📋 | Salidroside attenuates beta amyloid-induced cognitive deficits via modulating oxidative stress and inflammatory mediators in rat hippocampus |
| Salidroside | Alzheimer's Disease | 7 | PM | 23126197 | 📋 | [Study on effect and mechanism of salidroside on cognitive ability of Abeta1-40 -induced Alzheimer's disease model rats] |
| Salidroside | Alzheimer's Disease | 9 | PM | 22235318 | 📋 | Protective effects of a Rhodiola crenulata extract and salidroside on hippocampal neurogenesis against streptozotocin-induced neural injury in the rat |
| Salidroside | Brain Injury | 1 | PM | 35561751 | 📋 | Salidroside attenuates high altitude hypobaric hypoxia-induced brain injury in mice via inhibiting NF-κB/NLRP3 pathway |
| Salidroside | Chronic Stress | 1 | PM | 34168556 | 📋 | Salidroside Improves Chronic Stress Induced Depressive Symptoms Through Microglial Activation Suppression |
| Salidroside | Chronic Stress | 2 | PM | 30268794 | 📋 | Antidepressant-like effect of salidroside and curcumin on the immunoreactivity of rats subjected to a chronic mild stress model |
| Salidroside | Depression | 1 | PM | 35496273 | 📋 | Salidroside Ameliorates Depression by Suppressing NLRP3-Mediated Pyroptosis via P2X7/NF-κB/NLRP3 Signaling Pathway |
| Salidroside | Depression | 2 | PM | 34168556 | 📋 | Salidroside Improves Chronic Stress Induced Depressive Symptoms Through Microglial Activation Suppression |
| Salidroside | Depression | 7 | PM | 30268794 | 📋 | Antidepressant-like effect of salidroside and curcumin on the immunoreactivity of rats subjected to a chronic mild stress model |
| Salidroside | Depression | 6 | PM | 27214337 | 📋 | Rhodioloside ameliorates depressive behavior via up-regulation of monoaminergic system activity and anti-inflammatory effect in olfactory bulbectomized rats |
| Salidroside | Depression | 5 | PM | 26967223 | 📋 | Salidroside, a Bioactive Compound of Rhodiola Rosea, Ameliorates Memory and Emotional Behavior in Adult Mice |
| Salidroside | Depression | 4 | PM | 26300543 | 📋 | Salidroside attenuates lipopolysaccharide (LPS) induced serum cytokines and depressive-like behavior in mice |
| Salidroside | Depression | 3 | PM | 25101546 | 📋 | Antidepressant-like effects of salidroside on olfactory bulbectomy-induced pro-inflammatory cytokine production and hyperactivity of HPA axis in rats |
| Salidroside | Diabetic Encephalopathy | 3 | PM | 37490132 | 📋 | Neuroprotective effect of salidroside on hippocampal neurons in diabetic mice via PI3K/Akt/GSK-3β signaling pathway |
| Salidroside | Diabetic Encephalopathy | 1 | PM | 36509381 | 📋 | Salidroside alleviates diabetic cognitive dysfunction via B3galt2/F3/Contactin signaling pathway in mice |
| Salidroside | Diabetic Encephalopathy | 2 | PM | 30387819 | 📋 | Salidroside prevents diabetes‑induced cognitive impairment via regulating the Rho pathway |
| Salidroside | Diabetic Neuropathy | 1 | PM | 33639149 | 📋 | Salidroside alleviates diabetic neuropathic pain through regulation of the AMPK-NLRP3 inflammasome axis |
| Salidroside | Diabetic Neuropathy | 2 | PM | 28741143 | 📋 | Salidroside Ameliorates Diabetic Neuropathic Pain in Rats by Inhibiting Neuroinflammation |
| Salidroside | Epilepsy | 1 | PM | 32800786 | 📋 | Salidroside shows anticonvulsant and neuroprotective effects by activating the Nrf2-ARE pathway in a pentylenetetrazol-kindling epileptic model |
| Salidroside | Glioma | 1 | PM | 24255575 | 📋 | Effects of salidroside on glioma formation and growth inhibition together with improvement of tumor microenvironment |
| Salidroside | Huntington's Disease | 1 | PM | 30397021 | 📋 | Identification and Microbial Production of the Raspberry Phenol Salidroside that Is Active against Huntington's Disease |
| Salidroside | Ischemic Stroke | 7 | PM | 38488455 | 📋 | Salidroside directly activates HSC70, revealing a new role for HSC70 in BDNF signalling and neurogenesis after cerebral ischemia |
| Salidroside | Ischemic Stroke | 3 | PM | 36374318 | 📋 | Salidroside attenuates cerebral ischemia/reperfusion injury by regulating TSC2-induced autophagy |
| Salidroside | Ischemic Stroke | 2 | PM | 34988203 | 📋 | Salidroside inhibits NLRP3 inflammasome activation and apoptosis in microglia induced by cerebral ischemia/reperfusion injury by inhibiting the TLR4/NF-κB signaling pathway |
| Salidroside | Ischemic Stroke | 1 | PM | 33389472 | 📋 | Salidroside Inhibits Reactive Astrogliosis and Glial Scar Formation in Late Cerebral Ischemia via the Akt/GSK-3β Pathway |
| Salidroside | Ischemic Stroke | 6 | PM | 32603893 | 📋 | Salidroside as a potential neuroprotective agent for ischemic stroke: a review of sources, pharmacokinetics, mechanism and safety |
| Salidroside | Ischemic Stroke | 5 | PM | 32518214 | 📋 | Fibroblast growth factor 2 contributes to the effect of salidroside on dendritic and synaptic plasticity after cerebral ischemia/reperfusion injury |
| Salidroside | Ischemic Stroke | 4 | PM | 26889188 | 📋 | Neuroprotective effects of salidroside on focal cerebral ischemia/reperfusion injury involve the nuclear erythroid 2-related factor 2 pathway |
| Salidroside | Neurodegenerative Disease | 3 | PM | 30848530 | 📋 | Neuroprotective effect of salidroside against central nervous system inflammation-induced cognitive deficits: A pivotal role of sirtuin 1-dependent Nrf-2/HO-1/NF-κB pathway |
| Salidroside | Neurodegenerative Disease | 2 | PM | 28946765 | 📋 | Endoplasmic Reticulum Stress and NF-[Formula: see text]B Pathway in Salidroside Mediated Neuroprotection: Potential of Salidroside in Neurodegenerative Diseases |
| Salidroside | Neurodegenerative Disease | 1 | PM | 20615444 | 📋 | Neuroprotective effects of salidroside against beta-amyloid-induced oxidative stress in SH-SY5Y human neuroblastoma cells |
| Salidroside | Neuroinflammation | 2 | PM | 36948107 | 📋 | Salidroside attenuates lipopolysaccharide-induced neuroinflammation and cognitive impairment in septic encephalopathy mice |
| Salidroside | Neuroinflammation | 1 | PM | 35834964 | 📋 | Salidroside ameliorates orthopedic surgery-induced cognitive dysfunction by activating adenosine 5'-monophosphate-activated protein kinase signaling in mice |
| Salidroside | Neuroinflammation | 9 | PM | 31230155 | 📋 | Salidroside Reduces Inflammation and Brain Injury After Permanent Middle Cerebral Artery Occlusion in Rats by Regulating PI3K/PKB/Nrf2/NFκB Signaling Rather than Complement C3 Activity |
| Salidroside | Neuroinflammation | 8 | PM | 30848530 | 📋 | Neuroprotective effect of salidroside against central nervous system inflammation-induced cognitive deficits: A pivotal role of sirtuin 1-dependent Nrf-2/HO-1/NF-κB pathway |
| Salidroside | Neuroinflammation | 7 | PM | 29148269 | 📋 | Salidroside attenuates neuroinflammation and improves functional recovery after spinal cord injury through microglia polarization regulation |
| Salidroside | Neuroinflammation | 6 | PM | 28741143 | 📋 | Salidroside Ameliorates Diabetic Neuropathic Pain in Rats by Inhibiting Neuroinflammation |
| Salidroside | Neuroinflammation | 4 | PM | 28446004 | 📋 | Conditioned Medium Derived from Salidroside-Pretreated Mesenchymal Stem Cell Culture Ameliorates Mouse Lipopolysaccharide-Induced Cerebral Neuroinflammation- Histological and Immunohistochemical Study |
| Salidroside | Neuroinflammation | 5 | PM | 26909502 | 📋 | Salidroside suppresses inflammation in a D-galactose-induced rat model of Alzheimer's disease via SIRT1/NF-κB pathway |
| Salidroside | Neuroinflammation | 3 | PM | 26300543 | 📋 | Salidroside attenuates lipopolysaccharide (LPS) induced serum cytokines and depressive-like behavior in mice |
| Salidroside | Neurological Disorders | 2 | PM | 36228376 | 📋 | Pharmacological effects of salidroside on central nervous system diseases |
| Salidroside | Neurological Disorders | 1 | PM | 35834964 | 📋 | Salidroside ameliorates orthopedic surgery-induced cognitive dysfunction by activating adenosine 5'-monophosphate-activated protein kinase signaling in mice |
| Salidroside | Neuronal Damage | 4 | PM | 33240590 | 📋 | Effects of rhodioloside on the neurological functions of rats with total cerebral ischemia/reperfusion and cone neuron injury in the hippocampal CA1 region |
| Salidroside | Neuronal Damage | 6 | PM | 32774670 | 📋 | Salidroside Ameliorates Mitochondria-Dependent Neuronal Apoptosis after Spinal Cord Ischemia-Reperfusion Injury Partially through Inhibiting Oxidative Stress and Promoting Mitophagy |
| Salidroside | Neuronal Damage | 5 | PM | 31223467 | 📋 | Salidroside Protects Dopaminergic Neurons by Preserving Complex I Activity via DJ-1/Nrf2-Mediated Antioxidant Pathway |
| Salidroside | Neuronal Damage | 3 | PM | 29234413 | 📋 | Salidroside Protects against MPP+-Induced Neuronal Injury through DJ-1-Nrf2 Antioxidant Pathway |
| Salidroside | Neuronal Damage | 1 | PM | 27357827 | 📋 | Salidroside protects cortical neurons against glutamate-induced cytotoxicity by inhibiting autophagy |
| Salidroside | Neuronal Damage | 2 | PM | 26563497 | 📋 | Suppressing Receptor-Interacting Protein 140: a New Sight for Salidroside to Treat Cerebral Ischemia |
| Salidroside | Neuropathic Pain | 1 | PM | 34626306 | 📋 | Salidroside Alleviates Chronic Constriction Injury-Induced Neuropathic Pain and Inhibits of TXNIP/NLRP3 Pathway |
| Salidroside | Neurotoxicity | 7 | PM | 28465020 | 📋 | Salidroside attenuates colistin-induced neurotoxicity in RSC96 Schwann cells through PI3K/Akt pathway |
| Salidroside | Neurotoxicity | 4 | PM | 27103787 | 📋 | Neuroprotective effects of salidroside through PI3K/Akt pathway activation in Alzheimer's disease models |
| Salidroside | Neurotoxicity | 6 | PM | 26762342 | 📋 | Salidroside Protects Against 6-Hydroxydopamine-Induced Cytotoxicity by Attenuating ER Stress |
| Salidroside | Neurotoxicity | 3 | PM | 22095090 | 📋 | Neuroprotective effects of Salidroside and its analogue tyrosol galactoside against focal cerebral ischemia in vivo and H2O2-induced neurotoxicity in vitro |
| Salidroside | Neurotoxicity | 2 | PM | 22086763 | 📋 | Rhodiola rosea extract protects human cortical neurons against glutamate and hydrogen peroxide-induced cell death through reduction in the accumulation of intracellular calcium |
| Salidroside | Neurotoxicity | 5 | PM | 21499890 | 📋 | Neuroprotection against cobalt chloride-induced cell apoptosis of primary cultured cortical neurons by salidroside |
| Salidroside | Neurotoxicity | 1 | PM | 19787459 | 📋 | Involvement of ERK1/2 pathway in neuroprotection by salidroside against hydrogen peroxide-induced apoptotic cell death |
| Salidroside | Parkinson's Disease | 14 | PM | 38424396 | 📋 | Salidroside Mediated the Nrf2/GPX4 Pathway to Attenuates Ferroptosis in Parkinson's Disease |
| Salidroside | Parkinson's Disease | 1 | PM | 36130710 | 📋 | The therapeutic potential of salidroside for Parkinson's disease |
| Salidroside | Parkinson's Disease | 9 | PM | 32432571 | 📋 | Salidroside ameliorates Parkinson's disease by inhibiting NLRP3-dependent pyroptosis |
| Salidroside | Parkinson's Disease | 13 | PM | 31583052 | 📋 | Salidroside Protects Dopaminergic Neurons by Enhancing PINK1/Parkin-Mediated Mitophagy |
| Salidroside | Parkinson's Disease | 12 | PM | 31520529 | 📋 | Salidroside protects dopaminergic neurons by regulating the mitochondrial MEF2D-ND6 pathway in the MPTP/MPP+ -induced model of Parkinson's disease |
| Salidroside | Parkinson's Disease | 11 | PM | 31223467 | 📋 | Salidroside Protects Dopaminergic Neurons by Preserving Complex I Activity via DJ-1/Nrf2-Mediated Antioxidant Pathway |
| Salidroside | Parkinson's Disease | 10 | PM | 31180515 | 📋 | Salidroside protects SH‑SY5Y from pathogenic α‑synuclein by promoting cell autophagy via mediation of mTOR/p70S6K signaling |
| Salidroside | Parkinson's Disease | 3 | PM | 30548933 | 📋 | Salidroside protected against MPP+ -induced Parkinson's disease in PC12 cells by inhibiting inflammation, oxidative stress and cell apoptosis |
| Salidroside | Parkinson's Disease | 8 | PM | 29234413 | 📋 | Salidroside Protects against MPP+-Induced Neuronal Injury through DJ-1-Nrf2 Antioxidant Pathway |
| Salidroside | Parkinson's Disease | 5 | PM | 28851138 | 📋 | SIRT1 mediates salidroside-elicited protective effects against MPP+ -induced apoptosis and oxidative stress in SH-SY5Y cells: involvement in suppressing MAPK pathways |
| Salidroside | Parkinson's Disease | 7 | PM | 27738547 | 📋 | Neuroprotective Effects of Salidroside in the MPTP Mouse Model of Parkinson's Disease: Involvement of the PI3K/Akt/GSK3 β Pathway |
| Salidroside | Parkinson's Disease | 6 | PM | 26762342 | 📋 | Salidroside Protects Against 6-Hydroxydopamine-Induced Cytotoxicity by Attenuating ER Stress |
| Salidroside | Parkinson's Disease | 4 | PM | 24913834 | 📋 | Protective effects of salidroside in the MPTP/MPP(+)-induced model of Parkinson's disease through ROS-NO-related mitochondrion pathway |
| Salidroside | Parkinson's Disease | 2 | PM | 22664423 | 📋 | Salidroside protects PC12 cells from MPP⁺-induced apoptosis via activation of the PI3K/Akt pathway |
| Salidroside | Peripheral Nerve Injury | 1 | PM | 28054637 | 📋 | Salidroside promotes peripheral nerve regeneration based on tissue engineering strategy using Schwann cells and PLGA: in vitro and in vivo |
| Salidroside | Rheumatoid Arthritis | 2 | PM | 37851166 | 📋 | Salidroside suppresses cell growth and inflammatory response of fibroblast-like synoviocytes via inhibition of phosphoinositol-3 kinase/threonine kinase signaling in rheumatoid arthritis |
| Salidroside | Rheumatoid Arthritis | 1 | PM | 26690894 | 📋 | Salidroside ameliorates arthritis-induced brain cognition deficits by regulating Rho/ROCK/NF-κB pathway |
| Salidroside | Sciatic Nerve Injury | 2 | PM | 32053008 | 📋 | Salidroside promotes sciatic nerve regeneration following combined application epimysium conduit and Schwann cells in rats |
| Salidroside | Sciatic Nerve Injury | 1 | PM | 23358450 | 📋 | Salidroside promotes peripheral nerve regeneration following crush injury to the sciatic nerve in rats |
| Salidroside | Seizures | 1 | PM | 26940236 | 📋 | Salidroside protects against kainic acid-induced status epilepticus via suppressing oxidative stress |
| Salidroside | Spinal Cord Injury | 4 | PM | 38724500 | 📋 | Salidroside promotes the repair of spinal cord injury by inhibiting astrocyte polarization, promoting neural stem cell proliferation and neuronal differentiation |
| Salidroside | Spinal Cord Injury | 3 | PM | 31638093 | 📋 | Protective effect of rhodioloside and bone marrow mesenchymal stem cells infected with HIF-1-expressing adenovirus on acute spinal cord injury |
| Salidroside | Spinal Cord Injury | 2 | PM | 30656690 | 📋 | Salidroside promotes rat spinal cord injury recovery by inhibiting inflammatory cytokine expression and NF-κB and MAPK signaling pathways |
| Salidroside | Spinal Cord Injury | 1 | PM | 29148269 | 📋 | Salidroside attenuates neuroinflammation and improves functional recovery after spinal cord injury through microglia polarization regulation |
| Salidroside | Stress | 1 | PM | 22347152 | 📋 | Adaptogens stimulate neuropeptide y and hsp72 expression and release in neuroglia cells |
| Salidroside | Tourette Syndrome | 1 | PM | 26955685 | 📋 | [Effects of Salidroside on Tic Behavior of Tourette Syndrome Model Rats] |
| Salidroside | Traumatic Brain Injury | 1 | PM | 23029230 | 📋 | Salidroside improves behavioral and histological outcomes and reduces apoptosis via PI3K/Akt signaling after experimental traumatic brain injury |
| Salidroside | Vascular Dementia | 1 | PM | 32488778 | 📋 | Therapeutic Effects of Salidroside on Cognitive Ability in Rats with Experimental Vascular Dementia |
