| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Peony | Alzheimer's Disease | 1 | PM | 34494312 | 📋 | Peony seed oil ameliorates neuroinflammation-mediated cognitive deficits by suppressing microglial activation through inhibition of NF-κB pathway in presenilin 1/2 conditional double knockout mice |
| Peony | Alzheimer's Disease | 2 | PM | 31827565 | 📋 | A Network Pharmacology Approach to Reveal the Underlying Mechanisms of Paeonia lactiflora Pall. On the Treatment of Alzheimer's Disease |
| Peony | Depression | 2 | PM | 37295570 | 📋 | Paeonia lactiflora Pall. Polysaccharide alleviates depression in CUMS mice by inhibiting the NLRP3/ASC/Caspase-1 signaling pathway and affecting the composition of their intestinal flora |
| Peony | Depression | 1 | PM | 36188568 | 📋 | Essential oil from the roots of Paeonia lactiflora pall. has protective effect against corticosterone-induced depression in mice via modulation of PI3K/Akt signaling pathway |
| Peony | Depression | 4 | PM | 33308610 | 📋 | Antidepressant-like effects of albiflorin involved the NO signaling pathway in rats model of chronic restraint stress |
| Peony | Epilepsy | 2 | PM | 34511273 | 📋 | Anticonvulsant effects of Paeonia daurica subsp. macrophylla root extracts in pentylenetetrazol-induced seizure models in mice |
| Peony | Epilepsy | 1 | PM | 34388412 | 📋 | Efficacy and tolerability of hydroalcoholic extract of Paeonia officinalis in children with intractable epilepsy: An open-label pilot study |
| Peony | Ischemic Stroke | 1 | PM | 35938509 | 📋 | Combination of paeoniflorin and calycosin-7-glucoside alleviates ischaemic stroke injury via the PI3K/AKT signalling pathway |
| Peony | Migraine | 1 | PM | 31377466 | 📋 | Effect of Paeonia lactiflora, a traditional Chinese herb, on migraines based on clinical application and animal behavior analyses |
| Peony | Neurodegenerative Disease | 1 | PM | 37474737 | 📋 | Enhanced neuronal activity by suffruticosol A extracted from Paeonia lactiflora via partly BDNF signaling in scopolamine-induced memory-impaired mice |
| Peony | Neuroinflammation | 2 | PM | 37838295 | 📋 | Total Glucosides of White Paeony Capsule ameliorates Parkinson's disease-like behavior in MPTP-induced mice model by regulating LRRK2/alpha-synuclein signaling |
| Peony | Neuroinflammation | 1 | PM | 34494312 | 📋 | Peony seed oil ameliorates neuroinflammation-mediated cognitive deficits by suppressing microglial activation through inhibition of NF-κB pathway in presenilin 1/2 conditional double knockout mice |
| Peony | Neuropathic Pain | 2 | PM | 30622591 | 📋 | Bogijetong Decoction and Its Selected Formulation Are Involved in Alleviating Neuropathic Pain in a Rat Model of Chronic Constrictive Injury |
| Peony | Neuropathic Pain | 1 | PM | 23336442 | 📋 | Synergistic interaction between total glucosides and total flavonoids on chronic constriction injury induced neuropathic pain in rats |
| Peony | Parkinson's Disease | 2 | PM | 37838295 | 📋 | Total Glucosides of White Paeony Capsule ameliorates Parkinson's disease-like behavior in MPTP-induced mice model by regulating LRRK2/alpha-synuclein signaling |
| Peony | Parkinson's Disease | 1 | PM | 33381034 | 📋 | The Underlying Mechanism of Paeonia lactiflora Pall. in Parkinson's Disease Based on a Network Pharmacology Approach |
| Peony | Rheumatoid Arthritis | 3 | PM | 36296605 | 📋 | High-Throughput Metabolomics Integrated Network Pharmacology Reveals the Underlying Mechanism of Paeoniae Radix Alba Treating Rheumatoid Arthritis |
| Peony | Rheumatoid Arthritis | 2 | PM | 33897428 | 📋 | Combined Cornus Officinalis and Paeonia Lactiflora Pall Therapy Alleviates Rheumatoid Arthritis by Regulating Synovial Apoptosis via AMPK-Mediated Mitochondrial Fission |
| Peony | Rheumatoid Arthritis | 1 | PM | 33771151 | 📋 | Clinical safety of total glucosides of paeony adjuvant therapy for rheumatoid arthritis treatment: a systematic review and meta-analysis |
| Peony | Rheumatoid Arthritis | 6 | PM | 32186105 | 📋 | Total glucosides of paeony improve complete freund's adjuvant-induced rheumatoid arthritis in rats by inhibiting toll-like receptor 2-mediated tumor necrosis factor receptor-associated factor 6/ nuclear factor-kappa B pathway activation |
| Peony | Rheumatoid Arthritis | 5 | PM | 32172753 | 📋 | The effects of total glucosides of paeony (TGP) and paeoniflorin (Pae) on inflammatory-immune responses in rheumatoid arthritis (RA) |
| Peony | Rheumatoid Arthritis | 4 | PM | 29453823 | 📋 | Paeoniflorin ameliorates collagen-induced arthritis via suppressing nuclear factor-κB signalling pathway in osteoclast differentiation |
| Peony | Seizures | 1 | PM | 34388412 | 📋 | Efficacy and tolerability of hydroalcoholic extract of Paeonia officinalis in children with intractable epilepsy: An open-label pilot study |
