| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Nicotinamide | Alzheimer's Disease | 2 | PM | 32903806 | 📋 | Nicotinamide, a Poly [ADP-Ribose] Polymerase 1 (PARP-1) Inhibitor, as an Adjunctive Therapy for the Treatment of Alzheimer's Disease |
| Nicotinamide | Alzheimer's Disease | 1 | PM | 18987186 | 📋 | Nicotinamide Restores Cognition in Alzheimer's Disease Transgenic Mice via a Mechanism Involving Sirtuin Inhibition and Selective Reduction of Thr231-phosphotau |
| Nicotinamide | Demyelinating Disease | 1 | PM | 37663127 | 📋 | Nicotinamide enhances myelin production after demyelination through reduction of astrogliosis and microgliosis |
| Nicotinamide | Depression | 2 | PM | 33228716 | 📋 | Nicotinamide, a vitamin B3 ameliorates depressive behaviors independent of SIRT1 activity in mice |
| Nicotinamide | Depression | 1 | PM | 155389 | 📋 | Tryptophan-nicotinamide, Imipramine and Their Combination in Depression. A Controlled Study |
| Nicotinamide | Diabetic Neuropathy | 1 | PM | 35680173 | 📋 | Efficacy and safety of the combined metabolic medication, containing inosine, nicotinamide, riboflavin and succinic acid, for the treatment of diabetic neuropathy: a multicenter randomized, double-blind, placebo-controlled parallel group clinical trial (CYLINDER) |
| Nicotinamide | Neurodegenerative Disease | 1 | PM | 33397266 | 📋 | Nicotinamide as a Foundation for Treating Neurodegenerative Disease and Metabolic Disorders |
| Nicotinamide | Neuroinflammation | 3 | PM | 37513501 | 📋 | Nicotinamide Prevents Diabetic Brain Inflammation via NAD+-Dependent Deacetylation Mechanisms |
| Nicotinamide | Neuroinflammation | 2 | PM | 36428497 | 📋 | Neuroprotective Effects of Nicotinamide against MPTP-Induced Parkinson's Disease in Mice: Impact on Oxidative Stress, Neuroinflammation, Nrf2/HO-1 and TLR4 Signaling Pathways |
| Nicotinamide | Neuroinflammation | 1 | PM | 33920212 | 📋 | Nicotinamide Ameliorates Amyloid Beta-Induced Oxidative Stress-Mediated Neuroinflammation and Neurodegeneration in Adult Mouse Brain |
| Nicotinamide | Neuronal Damage | 2 | PM | 35612786 | 📋 | Bisphenol-A Mediated Impaired DRP1-GFER Axis and Cognition Restored by PGC-1α Upregulation Through Nicotinamide in the Rat Brain Hippocampus |
| Nicotinamide | Neuronal Damage | 1 | PM | 33920212 | 📋 | Nicotinamide Ameliorates Amyloid Beta-Induced Oxidative Stress-Mediated Neuroinflammation and Neurodegeneration in Adult Mouse Brain |
| Nicotinamide | Parkinson's Disease | 1 | PM | 36428497 | 📋 | Neuroprotective Effects of Nicotinamide against MPTP-Induced Parkinson's Disease in Mice: Impact on Oxidative Stress, Neuroinflammation, Nrf2/HO-1 and TLR4 Signaling Pathways |
| Nicotinamide | Schizophrenia | 2 | PM | 37210391 | 📋 | Nicotinamide ameliorates mitochondria-related neuronal apoptosis and cognitive impairment via the NAD+/SIRT3 pathway |
| Nicotinamide | Schizophrenia | 1 | PM | 37169164 | 📋 | SIRTUINS MODULATORS COUNTERACT MITOCHONDRIAL DYSFUNCTION IN CELLULAR MODELS OF HYPOXIA: RELEVANCE TO SCHIZOPHRENIA |
| Nicotinamide | Stroke | 1 | PM | 38734304 | 📋 | Acute combined cerebrolysin and nicotinamide administration promote cognitive recovery through neuronal changes in the hippocampus of rats with permanent middle cerebral artery occlusion |
