| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Mangiferin | Alzheimer's Disease | 2 | PM | 31271846 | 📋 | Mangiferin: A Multipotent Natural Product Preventing Neurodegeneration in Alzheimer's and Parkinson's Disease Models |
| Mangiferin | Alzheimer's Disease | 3 | PM | 30013719 | 📋 | Mangiferin and Morin Attenuate Oxidative Stress, Mitochondrial Dysfunction, and Neurocytotoxicity, Induced by Amyloid Beta Oligomers |
| Mangiferin | Alzheimer's Disease | 1 | PM | 27443159 | 📋 | Long-Term Mangiferin Extract Treatment Improves Central Pathology and Cognitive Deficits in APP/PS1 Mice |
| Mangiferin | Brain Inflammation | 1 | PM | 28455230 | 📋 | Mangiferin Attenuates Blast-Induced Traumatic Brain Injury via Inhibiting NLRP3 Inflammasome |
| Mangiferin | Dementia | 1 | PM | 31484797 | 📋 | Mechanism of Anti-Dementia Effects of Mangiferin in a Senescence Accelerated Mouse (SAMP8) Model |
| Mangiferin | Depression | 1 | PM | 28410265 | 📋 | Mangiferin Inhibits Hippocampal NLRP3 Inflammasome and Exerts Antidepressant Effects in a Chronic Mild Stress Mice Model |
| Mangiferin | Diabetic Neuropathy | 1 | PM | 38305392 | 📋 | Neuroprotective Effects of Isolated Mangiferin from Swertia chirayita Leaves Regulating Oxidative Pathway on Streptozotocin-Induced Diabetic Neuropathy in Experimental Rats |
| Mangiferin | Epilepsy | 1 | PM | 37486538 | 📋 | Anticonvulsive Effect of Glucosyl Xanthone Mangiferin on Pentylenetetrazol (PTZ)-Induced Seizure-Provoked Mice |
| Mangiferin | Glioblastoma | 1 | PM | 30272350 | 📋 | Mangiferin Induces Radiosensitization in Glioblastoma Cells by Inhibiting Nonhomologous End Joining |
| Mangiferin | Glioma | 1 | PM | 25901555 | 📋 | Mangiferin regulates proliferation and apoptosis in glioma cells by induction of microRNA-15b and inhibition of MMP-9 expression |
| Mangiferin | HIV/AIDS | 1 | PM | 8957579 | 📋 | Antitumor, Immunomodulatory and anti-HIV Effect of Mangiferin, a Naturally Occurring Glucosylxanthone |
| Mangiferin | Huntington's Disease | 1 | PM | 37521470 | 📋 | Neuroprotective potency of mangiferin against 3-nitropropionic acid induced Huntington's disease-like symptoms in rats: possible antioxidant and anti-inflammatory mechanisms |
| Mangiferin | Hyperalgesia | 1 | PM | 29715452 | 📋 | Local Administration of Mangiferin Prevents Experimental Inflammatory Mechanical Hyperalgesia Through CINC-1/epinephrine/PKA Pathway and TNF-α Inhibition |
| Mangiferin | Neurodegenerative Disease | 4 | PM | 33458836 | 📋 | Neuroprotective mechanisms of mangiferin in neurodegenerative diseases |
| Mangiferin | Neurodegenerative Disease | 3 | PM | 33078731 | 📋 | Mangiferin ameliorates intracerebroventricular-quinolinic acid-induced cognitive deficits, oxidative stress, and neuroinflammation in Wistar rats |
| Mangiferin | Neurodegenerative Disease | 2 | PM | 30633833 | 📋 | Neuroprotection of Mangiferin Against Oxidative Damage via Arousing Nrf2 Signaling Pathway in PC12 Cells |
| Mangiferin | Neurodegenerative Disease | 1 | PM | 30013719 | 📋 | Mangiferin and Morin Attenuate Oxidative Stress, Mitochondrial Dysfunction, and Neurocytotoxicity, Induced by Amyloid Beta Oligomers |
| Mangiferin | Neuroinflammation | 4 | PM | 33641782 | 📋 | Mangiferin inhibited neuroinflammation through regulating microglial polarization and suppressing NF-κB, NLRP3 pathway |
| Mangiferin | Neuroinflammation | 3 | PM | 33078731 | 📋 | Mangiferin ameliorates intracerebroventricular-quinolinic acid-induced cognitive deficits, oxidative stress, and neuroinflammation in Wistar rats |
| Mangiferin | Neuroinflammation | 1 | PM | 31271846 | 📋 | Mangiferin: A Multipotent Natural Product Preventing Neurodegeneration in Alzheimer's and Parkinson's Disease Models |
| Mangiferin | Neuroinflammation | 2 | PM | 28928429 | 📋 | Nrf2/HO-1 Mediates the Neuroprotective Effect of Mangiferin on Early Brain Injury After Subarachnoid Hemorrhage by Attenuating Mitochondria-Related Apoptosis and Neuroinflammation |
| Mangiferin | Neurological Disorders | 1 | PM | 33346032 | 📋 | Therapeutic Potential of Mangiferin in the Treatment of Various Neuropsychiatric and Neurodegenerative Disorders |
| Mangiferin | Neuropathic Pain | 2 | PM | 28940250 | 📋 | Synergistic Interaction of a Gabapentin- Mangiferin Combination in Formalin-Induced Secondary Mechanical Allodynia and Hyperalgesia in Rats Is Mediated by Activation of NO-Cyclic GMP-ATP-Sensitive K + Channel Pathway |
| Mangiferin | Neuropathic Pain | 1 | PM | 27984097 | 📋 | Anti-allodynic Effect of Mangiferin in Neuropathic Rats: Involvement of Nitric Oxide-Cyclic GMP-ATP Sensitive K + Channels Pathway and Serotoninergic System |
| Mangiferin | Neuropathic Pain | 3 | PM | 21150823 | 📋 | A Mangifera Indica L. Extract Could Be Used to Treat Neuropathic Pain and Implication of Mangiferin |
| Mangiferin | Neurotoxicity | 1 | PM | 37455591 | 📋 | C-Glucosyl Xanthone derivative Mangiferin downregulates the JNK3 mediated caspase activation in Almal induced neurotoxicity in differentiated SHSY-5Y neuroblastoma cells |
| Mangiferin | Parkinson's Disease | 6 | PM | 38142926 | 📋 | Mangiferin alleviates 6-OHDA-induced Parkinson's disease by inhibiting AKR1C3 to activate Wnt signaling pathway |
| Mangiferin | Parkinson's Disease | 5 | PM | 37036451 | 📋 | Neuroprotective Effect of Mangiferin against Parkinson's Disease through G-Protein-Coupled Receptor-Interacting Protein 1 (GIT1)-Mediated Antioxidant Defense |
| Mangiferin | Parkinson's Disease | 4 | PM | 35853641 | 📋 | Effects of mangiferin and its combination with nNOS inhibitor 7-nitro-indazole (7-NI) in 6-hydroxydopamine (6-OHDA) lesioned Parkinson's disease rats |
| Mangiferin | Parkinson's Disease | 3 | PM | 35752080 | 📋 | Mangiferin, a natural glucoxilxanthone, inhibits mitochondrial dynamin-related protein 1 and relieves aberrant mitophagic proteins in mice model of Parkinson's disease |
| Mangiferin | Parkinson's Disease | 2 | PM | 35341236 | 📋 | Pharmacological, Biochemical and Immunological Studies on Protective Effect of Mangiferin in 6-Hydroxydopamine (6-OHDA)-Induced Parkinson's Disease in Rats |
| Mangiferin | Parkinson's Disease | 1 | PM | 31271846 | 📋 | Mangiferin: A Multipotent Natural Product Preventing Neurodegeneration in Alzheimer's and Parkinson's Disease Models |
| Mangiferin | Postpartum Depression | 1 | PM | 35721155 | 📋 | Mangiferin Alleviates Postpartum Depression-Like Behaviors by Inhibiting MAPK Signaling in Microglia |
| Mangiferin | Rheumatoid Arthritis | 3 | PM | 38037139 | 📋 | Extensive preclinical evaluation of combined mangiferin and glycyrrhizic acid for restricting synovial neovascularization in rheumatoid arthritis |
| Mangiferin | Rheumatoid Arthritis | 2 | PM | 35799788 | 📋 | A Novel Drug Combination of Mangiferin and Cinnamic Acid Alleviates Rheumatoid Arthritis by Inhibiting TLR4/NFκB/NLRP3 Activation-Induced Pyroptosis |
| Mangiferin | Rheumatoid Arthritis | 1 | PM | 35749826 | 📋 | A promising drug combination of mangiferin and glycyrrhizic acid ameliorates disease severity of rheumatoid arthritis by reversing the disturbance of thermogenesis and energy metabolism |
| Mangiferin | Subarachnoid Hemorrhage | 1 | PM | 28928429 | 📋 | Nrf2/HO-1 Mediates the Neuroprotective Effect of Mangiferin on Early Brain Injury After Subarachnoid Hemorrhage by Attenuating Mitochondria-Related Apoptosis and Neuroinflammation |
| Mangiferin | Traumatic Brain Injury | 1 | PM | 28455230 | 📋 | Mangiferin Attenuates Blast-Induced Traumatic Brain Injury via Inhibiting NLRP3 Inflammasome |
