| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Guggulsterone | Alzheimer's Disease | 1 | PM | 35714682 | 📋 | Z-Guggulsterone attenuates cognitive defects and decreases neuroinflammation in APPswe/PS1dE9 mice through inhibiting the TLR4 signaling pathway |
| Guggulsterone | Amyotrophic Lateral Sclerosis | 1 | PM | 38170440 | 📋 | Guggulsterone Selectively Modulates STAT-3, mTOR, and PPAR-Gamma Signaling in a Methylmercury-Exposed Experimental Neurotoxicity: Evidence from CSF, Blood Plasma, and Brain Samples |
| Guggulsterone | Depression | 1 | PM | 28339691 | 📋 | Z-Guggulsterone Produces Antidepressant-Like Effects in Mice through Activation of the BDNF Signaling Pathway |
| Guggulsterone | Glioblastoma | 2 | PM | 36436590 | 📋 | Guggulsterone inhibits migration and invasion through proteasomal and lysosomal degradation in human glioblastoma cells |
| Guggulsterone | Glioblastoma | 1 | PM | 36280019 | 📋 | Guggulsterone from Commiphora mukul potentiates anti-glioblastoma efficacy of temozolomide in vitro and in vivo via down-regulating EGFR/PI3K/Akt signaling and NF-κB activation |
| Guggulsterone | Ischemic Stroke | 2 | PM | 37230158 | 📋 | Novel synergistic mechanism of 11-keto-β-boswellic acid and Z-Guggulsterone on ischemic stroke revealed by single-cell transcriptomics |
| Guggulsterone | Ischemic Stroke | 1 | PM | 30168601 | 📋 | Z-Guggulsterone attenuates astrocytes-mediated neuroinflammation after ischemia by inhibiting toll-like receptor 4 pathway |
| Guggulsterone | Multiple Sclerosis | 1 | PM | 33635478 | 📋 | Guggulsterone ameliorates ethidium bromide-induced experimental model of multiple sclerosis via restoration of behavioral, molecular, neurochemical and morphological alterations in rat brain |
| Guggulsterone | Neuroinflammation | 3 | PM | 35714682 | 📋 | Z-Guggulsterone attenuates cognitive defects and decreases neuroinflammation in APPswe/PS1dE9 mice through inhibiting the TLR4 signaling pathway |
| Guggulsterone | Neuroinflammation | 2 | PM | 30168601 | 📋 | Z-Guggulsterone attenuates astrocytes-mediated neuroinflammation after ischemia by inhibiting toll-like receptor 4 pathway |
| Guggulsterone | Neuroinflammation | 1 | PM | 26879835 | 📋 | Z-guggulsterone negatively controls microglia-mediated neuroinflammation via blocking IκB-α-NF-κB signals |
| Guggulsterone | Neuropathic Pain | 1 | PM | 35546904 | 📋 | Z-Guggulsterone Relieves Neuropathic Pain by Inhibiting the Expression of Astrocytes and Proinflammatory Cytokines in the Spinal Dorsal Horn |
