| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Ganoderic Acid | Alzheimer's Disease | 5 | PM | 37287673 | 📋 | Identification of potential neuroprotective compound from Ganoderma lucidum extract targeting microtubule affinity regulation kinase 4 involved in Alzheimer's disease through molecular dynamics simulation and MMGBSA |
| Ganoderic Acid | Alzheimer's Disease | 1 | PM | 34798773 | 📋 | Ganoderic Acid A To Alleviate Neuroinflammation of Alzheimer's Disease in Mice by Regulating the Imbalance of the Th17/Tregs Axis |
| Ganoderic Acid | Alzheimer's Disease | 2 | PM | 34074054 | 📋 | Ganoderic Acid A Promotes Amyloid-β Clearance (In Vitro) and Ameliorates Cognitive Deficiency in Alzheimer's Disease (Mouse Model) through Autophagy Induced by Activating Axl |
| Ganoderic Acid | Alzheimer's Disease | 4 | PM | 33963744 | 📋 | PADI4 mediates autophagy and participates in the role of ganoderic acid A monomers in delaying the senescence of Alzheimer's cells through the Akt/mTOR pathway |
| Ganoderic Acid | Alzheimer's Disease | 3 | PM | 30971923 | 📋 | Alcohol Extracts From Ganoderma lucidum Delay the Progress of Alzheimer's Disease by Regulating DNA Methylation in Rodents |
| Ganoderic Acid | Brain Tumor | 1 | PM | 25864108 | 📋 | A novel component from citrus, ginger, and mushroom family exhibits antitumor activity on human meningioma cells through suppressing the Wnt/β-catenin signaling pathway |
| Ganoderic Acid | Depression | 2 | PM | 38723681 | 📋 | Ganoderic acid A ameliorates depressive-like behaviors in CSDS mice: Insights from proteomic profiling and molecular mechanisms |
| Ganoderic Acid | Depression | 1 | PM | 33857491 | 📋 | Ganoderic acid A exerted antidepressant-like action through FXR modulated NLRP3 inflammasome and synaptic activity |
| Ganoderic Acid | Epilepsy | 2 | PM | 36093409 | 📋 | Investigation into Antiepileptic Effect of Ganoderic Acid A and Its Mechanism in Seizure Rats Induced by Pentylenetetrazole |
| Ganoderic Acid | Epilepsy | 1 | PM | 29442010 | 📋 | Ganoderic acid A potentiates the antioxidant effect and protection of mitochondrial membranes and reduces the apoptosis rate in primary hippocampal neurons in magnesium free medium |
| Ganoderic Acid | HIV/AIDS | 1 | PM | 22347784 | 📋 | Interaction of ganoderic acid on HIV related target: molecular docking studies |
| Ganoderic Acid | HIV/AIDS | 2 | PM | 9810695 | 📋 | Triterpenes from the spores of Ganoderma lucidum and their inhibitory activity against HIV-1 protease |
| Ganoderic Acid | Multiple Sclerosis | 1 | PM | 33482151 | 📋 | Activation of FXR by ganoderic acid A promotes remyelination in multiple sclerosis via anti-inflammation and regeneration mechanism |
| Ganoderic Acid | Neuroinflammation | 1 | PM | 34798773 | 📋 | Ganoderic Acid A To Alleviate Neuroinflammation of Alzheimer's Disease in Mice by Regulating the Imbalance of the Th17/Tregs Axis |
| Ganoderic Acid | Neuroinflammation | 4 | PM | 34421302 | 📋 | Ganoderic Acid A-Mediated Modulation of Microglial Polarization is Involved in Depressive-Like Behaviors and Neuroinflammation in a Rat Model of Post-Stroke Depression |
| Ganoderic Acid | Neuroinflammation | 2 | PM | 33821438 | 📋 | Ganoderic Acid A Attenuates LPS-Induced Neuroinflammation in BV2 Microglia by Activating Farnesoid X Receptor |
| Ganoderic Acid | Neuroinflammation | 3 | PM | 31892211 | 📋 | Deacetyl Ganoderic Acid F Inhibits LPS-Induced Neural Inflammation via NF-κB Pathway Both In Vitro and In Vivo |
| Ganoderic Acid | Neurological Disorders | 1 | PM | 38421693 | 📋 | Ganoderic Acid A: A Potential Natural Neuroprotective Agent for Neurological Disorders: A Review |
| Ganoderic Acid | Parkinson's Disease | 1 | PM | 38763373 | 📋 | Ganoderic acid A mitigates dopaminergic neuron ferroptosis via inhibiting NCOA4-mediated ferritinophagy in Parkinson's disease mice |
