| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Curcumin | Age-Related Cognitive Decline | 10 | PM | 37542120 | 📋 | Combination of epigallocatechin 3 gallate and curcumin improves D-galactose and normal-aging associated memory impairment in mice |
| Curcumin | Age-Related Cognitive Decline | 9 | PM | 35767571 | 📋 | Curcumin improves D-galactose and normal-aging associated memory impairment in mice: In vivo and in silico-based studies |
| Curcumin | Age-Related Cognitive Decline | 8 | PM | 35334842 | 📋 | Curcumin-Rich Curry Consumption and Neurocognitive Function from 4.5-Year Follow-Up of Community-Dwelling Older Adults (Singapore Longitudinal Ageing Study) |
| Curcumin | Age-Related Cognitive Decline | 7 | PM | 35334275 | 📋 | Curcumin induces cortico-hippocampal neuronal reshaping and memory improvements in aged mice |
| Curcumin | Age-Related Cognitive Decline | 6 | PM | 34715442 | 📋 | Age-related alterations to working memory and to pyramidal neurons in the prefrontal cortex of rhesus monkeys begin in early middle-age and are partially ameliorated by dietary curcumin |
| Curcumin | Age-Related Cognitive Decline | 5 | PM | 33217959 | 📋 | Curcumin Formulations and Trials: What's New in Neurological Diseases |
| Curcumin | Age-Related Cognitive Decline | 4 | PM | 32512782 | 📋 | Further Evidence of Benefits to Mood and Working Memory From Lipidated Curcumin in Healthy Older People: A 12-Week, Double-Blind, Placebo-Controlled, Partial Replication Study |
| Curcumin | Age-Related Cognitive Decline | 1 | PM | 22359574 | 📋 | Curcumin Enhances Neurogenesis and Cognition in Aged Rats: Implications for Transcriptional Interactions Related to Growth and Synaptic Plasticity |
| Curcumin | Age-Related Cognitive Decline | 2 | PM | 20619287 | 📋 | Neuroprotective Effects of the Polyphenolic Antioxidant Agent, Curcumin, Against Homocysteine-Induced Cognitive Impairment and Oxidative Stress in the Rat |
| Curcumin | Age-Related Cognitive Decline | 3 | PM | 20553189 | 📋 | Curcumin Exerts Neuroprotective Effects Against Homocysteine Intracerebroventricular Injection-Induced Cognitive Impairment and Oxidative Stress in Rat Brain |
| Curcumin | Alzheimer's Disease | 82 | PM | 38791161 | 📋 | Curcumin Improves Neurogenesis in Alzheimer's Disease Mice via the Upregulation of Wnt/β-Catenin and BDNF |
| Curcumin | Alzheimer's Disease | 81 | PM | 38616356 | 📋 | Neuroprotective and anti-inflammatory effects of curcumin in Alzheimer's disease: Targeting neuroinflammation strategies |
| Curcumin | Alzheimer's Disease | 80 | PM | 38265680 | 📋 | Therapeutic potential of curcumin on the cognitive decline in animal models of Alzheimer's disease: a systematic review and meta-analysis |
| Curcumin | Alzheimer's Disease | 79 | PM | 38257133 | 📋 | Curcumin Mitigates the High-Fat High-Sugar Diet-Induced Impairment of Spatial Memory, Hepatic Metabolism, and the Alteration of the Gut Microbiome in Alzheimer's Disease-Induced (3xTg-AD) Mice |
| Curcumin | Alzheimer's Disease | 78 | PM | 37989445 | 📋 | Curcumin alleviates Alzheimer's disease by inhibiting inflammatory response, oxidative stress and activating the AMPK pathway |
| Curcumin | Alzheimer's Disease | 77 | PM | 37566247 | 📋 | Effect of Curcumin on Cognitive Behavior and Pathological Characteristics of the Hippocampus in Mice with Inherent Alzheimer's Disease |
| Curcumin | Alzheimer's Disease | 75 | PM | 37239093 | 📋 | Effect of Curcumin and Coenzyme Q10 Alone and in Combination on Learning and Memory in an Animal Model of Alzheimer's Disease |
| Curcumin | Alzheimer's Disease | 73 | PM | 36856916 | 📋 | Protective effects of curcumin and Ginkgo biloba extract combination on a new model of Alzheimer's disease |
| Curcumin | Alzheimer's Disease | 72 | PM | 36652025 | 📋 | Network pharmacology and bioinformatics approach reveals the therapeutic mechanism of action of curcumin in Alzheimer disease |
| Curcumin | Alzheimer's Disease | 71 | PM | 36105064 | 📋 | Curcumin prevents Alzheimer's disease progression by upregulating JMJD3 |
| Curcumin | Alzheimer's Disease | 70 | PM | 36077082 | 📋 | Combined Treatment with Curcumin and Ferulic Acid Suppressed the Aβ-Induced Neurotoxicity More than Curcumin and Ferulic Acid Alone |
| Curcumin | Alzheimer's Disease | 69 | PM | 36069210 | 📋 | Curcumin improves the ability of donepezil to ameliorate memory impairment in Drosophila melanogaster: involvement of cholinergic and cnc/Nrf2-redox systems |
| Curcumin | Alzheimer's Disease | 68 | PM | 36042609 | 📋 | A network pharmacology approach to identify the mechanisms and molecular targets of curcumin against Alzheimer disease |
| Curcumin | Alzheimer's Disease | 67 | PM | 35963200 | 📋 | Protective and anti-oxidative effects of curcumin and resveratrol on Aβ-oligomer-induced damage in the SH-SY5Y cell line |
| Curcumin | Alzheimer's Disease | 66 | PM | 35662729 | 📋 | Curcumin as a Holistic Treatment for Tau Pathology |
| Curcumin | Alzheimer's Disease | 65 | PM | 35294663 | 📋 | Pharmacological considerations for treating neuroinflammation with curcumin in Alzheimer's disease |
| Curcumin | Alzheimer's Disease | 64 | PM | 35178203 | 📋 | Improvement of cognitive deficit of curcumin on scopolamine-induced Alzheimer's disease models |
| Curcumin | Alzheimer's Disease | 63 | PM | 35176983 | 📋 | A new perspective on the treatment of Alzheimer's disease and sleep deprivation-related conse-quences: Curcumin |
| Curcumin | Alzheimer's Disease | 60 | PM | 35069976 | 📋 | A New Perspective on the Treatment of Alzheimer's Disease and Sleep Deprivation-Related Consequences: Can Curcumin Help? |
| Curcumin | Alzheimer's Disease | 30 | PM | 35035682 | 📋 | Curcumin slows the progression of Alzheimer's disease by modulating mitochondrial stress responses via JMJD3-H3K27me3-BDNF axis |
| Curcumin | Alzheimer's Disease | 29 | PM | 34997713 | 📋 | Curcumin ameliorates lipid metabolic disorder and cognitive dysfunction via the ABCA1 transmembrane transport system in APP/PS1 double transgenic mice |
| Curcumin | Alzheimer's Disease | 62 | PM | 34405526 | 📋 | Curcumin improves memory deficits by inhibiting HMGB1-RAGE/TLR4-NF-κB signalling pathway in APPswe/PS1dE9 transgenic mice hippocampus |
| Curcumin | Alzheimer's Disease | 61 | PM | 34401962 | 📋 | Curcumin Alleviates Aβ 42-Induced Neuronal Metabolic Dysfunction via the Thrb/SIRT3 Axis and Improves Cognition in APP TG Mice |
| Curcumin | Alzheimer's Disease | 59 | PM | 34208692 | 📋 | Action Mechanisms of Curcumin in Alzheimer's Disease and Its Brain Targeted Delivery |
| Curcumin | Alzheimer's Disease | 58 | PM | 34070220 | 📋 | Curcumin Attenuated Neurotoxicity in Sporadic Animal Model of Alzheimer's Disease |
| Curcumin | Alzheimer's Disease | 57 | PM | 33557949 | 📋 | Preservation of dendritic spine morphology and postsynaptic signaling markers after treatment with solid lipid curcumin particles in the 5xFAD mouse model of Alzheimer's amyloidosis |
| Curcumin | Alzheimer's Disease | 56 | PM | 33375513 | 📋 | Curcumin and Its Derivatives as Theranostic Agents in Alzheimer's Disease: The Implication of Nanotechnology |
| Curcumin | Alzheimer's Disease | 55 | PM | 33237490 | 📋 | Effects of Curcumin and Boric Acid Against Neurodegenerative Damage Induced by Amyloid Beta (1-42) |
| Curcumin | Alzheimer's Disease | 54 | PM | 33062432 | 📋 | Explicating anti-amyloidogenic role of curcumin and piperine via amyloid beta (A β) explicit pathway: recovery and reversal paradigm effects |
| Curcumin | Alzheimer's Disease | 53 | PM | 33029254 | 📋 | Retinal Levels of Amyloid Beta Correlate with Cerebral Levels of Amyloid Beta in Young APPswe/PS1dE9 Transgenic Mice before Onset of Alzheimer's Disease |
| Curcumin | Alzheimer's Disease | 52 | PM | 32528227 | 📋 | Therapeutic Potential of Vitamin D and Curcumin in an In Vitro Model of Alzheimer Disease |
| Curcumin | Alzheimer's Disease | 42 | PM | 32448977 | 📋 | Potentiation of anti-Alzheimer Activity of Curcumin by Probiotic Lactobacillus Rhamnosus UBLR-58 Against Scopolamine-Induced Memory Impairment in Mice |
| Curcumin | Alzheimer's Disease | 1 | PM | 32175381 | 📋 | Protective Effects of Curcumin Against Neuroinflammation Induced by Aβ25-35 in Primary Rat Microglia: Modulation of High-Mobility Group Box 1, Toll-Like Receptor 4 and Receptor for Advanced Glycation End Products Expression |
| Curcumin | Alzheimer's Disease | 2 | PM | 32080784 | 📋 | Synergic Effects of Berberine and Curcumin on Improving Cognitive Function in an Alzheimer's Disease Mouse Model |
| Curcumin | Alzheimer's Disease | 16 | PM | 31754658 | 📋 | Curcumin Downregulates GSK3 and Cdk5 in Scopolamine-Induced Alzheimer's Disease Rats Abrogating Aβ 40/42 and Tau Hyperphosphorylation |
| Curcumin | Alzheimer's Disease | 3 | PM | 31507403 | 📋 | Synergistic Effects of Curcumin and Piperine as Potent Acetylcholine and Amyloidogenic Inhibitors With Significant Neuroprotective Activity in SH-SY5Y Cells via Computational Molecular Modeling and in vitro Assay |
| Curcumin | Alzheimer's Disease | 22 | PM | 30951849 | 📋 | Curcumin Restores Innate Immune Alzheimer's Disease Risk Gene Expression to Ameliorate Alzheimer Pathogenesis |
| Curcumin | Alzheimer's Disease | 48 | PM | 29894862 | 📋 | Phytochemicals Inhibit the Immunosuppressive Functions of Myeloid-Derived Suppressor Cells (MDSC): Impact on Cancer and Age-Related Chronic Inflammatory Disorders |
| Curcumin | Alzheimer's Disease | 4 | PM | 29614668 | 📋 | A Study of a Supplement Containing Huperzine A and Curcumin in Dementia Patients and Individuals With Mild Cognitive Impairment |
| Curcumin | Alzheimer's Disease | 10 | PM | 28527659 | 📋 | Curcumin Administration Suppress Acetylcholinesterase Gene Expression in Cadmium Treated Rats |
| Curcumin | Alzheimer's Disease | 50 | PM | 28527218 | 📋 | The Mechanisms of Action of Curcumin in Alzheimer's Disease |
| Curcumin | Alzheimer's Disease | 20 | PM | 27466310 | 📋 | Curcumin Ameliorates Insulin Signalling Pathway in Brain of Alzheimer's Disease Transgenic Mice |
| Curcumin | Alzheimer's Disease | 28 | PM | 27388114 | 📋 | Amelioration of Scopolamine-Induced Amnesia by Phosphatidylserine and Curcumin in the Day-Old Chick |
| Curcumin | Alzheimer's Disease | 13 | PM | 27060945 | 📋 | Antioxidative and Neuroprotective Effects of Curcumin in an Alzheimer's Disease Rat Model Co-Treated With Intracerebroventricular Streptozotocin and Subcutaneous D-Galactose |
| Curcumin | Alzheimer's Disease | 18 | PM | 26923403 | 📋 | Curcumin Improves Tau-Induced Neuronal Dysfunction of Nematodes |
| Curcumin | Alzheimer's Disease | 36 | PM | 26824354 | 📋 | Curcumin Ameliorates the Reduction Effect of PGE2 on Fibrillar β-Amyloid Peptide (1-42)-Induced Microglial Phagocytosis Through the Inhibition of EP2-PKA Signaling in N9 Microglial Cells |
| Curcumin | Alzheimer's Disease | 24 | PM | 26638997 | 📋 | Downstream Modulation of Extrinsic Apoptotic Pathway in Streptozotocin-Induced Alzheimer's Dementia in Rats: Erythropoietin Versus Curcumin |
| Curcumin | Alzheimer's Disease | 47 | PM | 26618861 | 📋 | Neuronal Uptake and Neuroprotective Properties of Curcumin-Loaded Nanoparticles on SK-N-SH Cell Line: Role of Poly(lactide-co-glycolide) Polymeric Matrix Composition |
| Curcumin | Alzheimer's Disease | 32 | PM | 26529184 | 📋 | Curcumin Attenuates Amyloid-β Aggregate Toxicity and Modulates Amyloid-β Aggregation Pathway |
| Curcumin | Alzheimer's Disease | 31 | PM | 26487830 | 📋 | Curcumin and Apigenin - Novel and Promising Therapeutics Against Chronic Neuroinflammation in Alzheimer's Disease |
| Curcumin | Alzheimer's Disease | 7 | PM | 26053510 | 📋 | Protection of Curcumin Against Amyloid-β-Induced Cell Damage and Death Involves the Prevention From NMDA Receptor-Mediated Intracellular Ca2+ Elevation |
| Curcumin | Alzheimer's Disease | 25 | PM | 26035833 | 📋 | Curcumin Treatment Improves Motor Behavior in α-Synuclein Transgenic Mice |
| Curcumin | Alzheimer's Disease | 41 | PM | 25818332 | 📋 | Curcumin Inhibits Aβ-induced Microglial Inflammatory Responses in Vitro: Involvement of ERK1/2 and p38 Signaling Pathways |
| Curcumin | Alzheimer's Disease | 33 | PM | 25776887 | 📋 | Curcumin Binding to Beta Amyloid: A Computational Study |
| Curcumin | Alzheimer's Disease | 76 | PM | 24035895 | 📋 | Curcumin-induced upregulation of the anti-tau cochaperone BAG2 in primary rat cortical neurons |
| Curcumin | Alzheimer's Disease | 74 | PM | 21939756 | 📋 | Natural substances and Alzheimer's disease: from preclinical studies to evidence based medicine |
| Curcumin | Alzheimer's Disease | 45 | PM | 20963814 | 📋 | Curcuminoids Rescue Long-Term Potentiation Impaired by Amyloid Peptide in Rat Hippocampal Slices |
| Curcumin | Alzheimer's Disease | 37 | PM | 20840842 | 📋 | Potential Therapeutic Effects of Curcumin: Relationship to Microtubule-Associated Proteins 2 in Aβ1-42 Insult |
| Curcumin | Alzheimer's Disease | 34 | PM | 20727383 | 📋 | The Inhibitory Effects of Different Curcuminoids on β-Amyloid Protein, β-Amyloid Precursor Protein and β-Site Amyloid Precursor Protein Cleaving Enzyme 1 in swAPP HEK293 Cells |
| Curcumin | Alzheimer's Disease | 38 | PM | 20638958 | 📋 | Potential Protection of Curcumin Against Intracellular Amyloid Beta-Induced Toxicity in Cultured Rat Prefrontal Cortical Neurons |
| Curcumin | Alzheimer's Disease | 14 | PM | 20622013 | 📋 | Curcumin Decreases Amyloid-Beta Peptide Levels by Attenuating the Maturation of Amyloid-Beta Precursor Protein |
| Curcumin | Alzheimer's Disease | 26 | PM | 20538041 | 📋 | Curcuminoids Enhance Memory in an Amyloid-Infused Rat Model of Alzheimer's Disease |
| Curcumin | Alzheimer's Disease | 39 | PM | 20413894 | 📋 | PPARgamma Agonist Curcumin Reduces the Amyloid-Beta-Stimulated Inflammatory Responses in Primary Astrocytes |
| Curcumin | Alzheimer's Disease | 49 | PM | 19966973 | 📋 | The Effect of Curcumin (Turmeric) on Alzheimer's Disease: An Overview |
| Curcumin | Alzheimer's Disease | 51 | PM | 19715544 | 📋 | Optimized Turmeric Extracts Have Potent Anti-Amyloidogenic Effects |
| Curcumin | Alzheimer's Disease | 6 | PM | 19433889 | 📋 | 1alpha,25-dihydroxyvitamin D3 Interacts With Curcuminoids to Stimulate Amyloid-Beta Clearance by Macrophages of Alzheimer's Disease Patients |
| Curcumin | Alzheimer's Disease | 11 | PM | 19329286 | 📋 | Amelioration of Cognitive Deficits and Neurodegeneration by Curcumin in Rat Model of Sporadic Dementia of Alzheimer's Type (SDAT) |
| Curcumin | Alzheimer's Disease | 27 | PM | 19027755 | 📋 | Grape Seed Polyphenols and Curcumin Reduce Genomic Instability Events in a Transgenic Mouse Model for Alzheimer's Disease |
| Curcumin | Alzheimer's Disease | 17 | PM | 18701050 | 📋 | Curcumin Improves Learning and Memory Ability and Its Neuroprotective Mechanism in Mice |
| Curcumin | Alzheimer's Disease | 46 | PM | 18695518 | 📋 | Epigallocatechin-3-gallate and Curcumin Suppress Amyloid Beta-Induced Beta-Site APP Cleaving enzyme-1 Upregulation |
| Curcumin | Alzheimer's Disease | 40 | PM | 18573304 | 📋 | Curcumin Protected PC12 Cells Against Beta-Amyloid-Induced Toxicity Through the Inhibition of Oxidative Damage and Tau Hyperphosphorylation |
| Curcumin | Alzheimer's Disease | 15 | PM | 18417733 | 📋 | Curcumin Structure-Function, Bioavailability, and Efficacy in Models of Neuroinflammation and Alzheimer's Disease |
| Curcumin | Alzheimer's Disease | 35 | PM | 17996023 | 📋 | Curcumin Binds to the Alpha-Helical Intermediate and to the Amyloid Form of Prion Protein - A New Mechanism for the Inhibition of PrP(Sc) Accumulation |
| Curcumin | Alzheimer's Disease | 23 | PM | 17472706 | 📋 | Curcumin Labels Amyloid Pathology in Vivo, Disrupts Existing Plaques, and Partially Restores Distorted Neurites in an Alzheimer Mouse Model |
| Curcumin | Alzheimer's Disease | 5 | PM | 16988474 | 📋 | Curcuminoids Enhance Amyloid-Beta Uptake by Macrophages of Alzheimer's Disease Patients |
| Curcumin | Alzheimer's Disease | 8 | PM | 15590663 | 📋 | Curcumin Inhibits Formation of Amyloid Beta Oligomers and Fibrils, Binds Plaques, and Reduces Amyloid in Vivo |
| Curcumin | Alzheimer's Disease | 19 | PM | 15569263 | 📋 | Curcumin, the Active Constituent of Turmeric, Inhibits Amyloid Peptide-Induced Cytochemokine Gene Expression and CCR5-mediated Chemotaxis of THP-1 Monocytes by Modulating Early Growth response-1 Transcription Factor |
| Curcumin | Alzheimer's Disease | 43 | PM | 15345806 | 📋 | Curcumin Interaction With Copper and Iron Suggests One Possible Mechanism of Action in Alzheimer's Disease Animal Models |
| Curcumin | Alzheimer's Disease | 12 | PM | 14994335 | 📋 | Curcumin Has Potent Anti-Amyloidogenic Effects for Alzheimer's Beta-Amyloid Fibrils in Vitro |
| Curcumin | Alzheimer's Disease | 21 | PM | 11755008 | 📋 | Phenolic Anti-Inflammatory Antioxidant Reversal of Abeta-induced Cognitive Deficits and Neuropathology |
| Curcumin | Alzheimer's Disease | 9 | PM | 11606625 | 📋 | The Curry Spice Curcumin Reduces Oxidative Damage and Amyloid Pathology in an Alzheimer Transgenic Mouse |
| Curcumin | Alzheimer's Disease | 44 | PM | 11297823 | 📋 | Curcuminoids From Curcuma Longa L. (Zingiberaceae) That Protect PC12 Rat Pheochromocytoma and Normal Human Umbilical Vein Endothelial Cells From betaA(1-42) Insult |
| Curcumin | Amyotrophic Lateral Sclerosis | 6 | PM | 33672485 | 📋 | The Impact of Microbiota on the Pathogenesis of Amyotrophic Lateral Sclerosis and the Possible Benefits of Polyphenols. An Overview |
| Curcumin | Amyotrophic Lateral Sclerosis | 2 | PM | 24785678 | 📋 | Curcumin Abolishes Mutant TDP-43 Induced Excitability in a Motoneuron-Like Cellular Model of ALS |
| Curcumin | Amyotrophic Lateral Sclerosis | 3 | PM | 23934646 | 📋 | Neuroprotection by Monocarbonyl Dimethoxycurcumin C: Ameliorating the Toxicity of Mutant TDP-43 via HO-1 |
| Curcumin | Amyotrophic Lateral Sclerosis | 4 | PM | 22986236 | 📋 | Mitochondrial Dysfunction in Human TDP-43 Transfected NSC34 Cell Lines and the Protective Effect of Dimethoxy Curcumin |
| Curcumin | Amyotrophic Lateral Sclerosis | 5 | PM | 22156608 | 📋 | Curcumins Promote Monocytic Gene Expression Related to β-Amyloid and Superoxide Dismutase Clearance |
| Curcumin | Amyotrophic Lateral Sclerosis | 1 | PM | 15934930 | 📋 | Sodium Phenylbutyrate Prolongs Survival and Regulates Expression of Anti-Apoptotic Genes in Transgenic Amyotrophic Lateral Sclerosis Mice |
| Curcumin | Brain Edema | 5 | PM | 34630953 | 📋 | Evaluation of the protective effect of curcumin on encephalopathy caused by intrahepatic and extrahepatic damage in male rats |
| Curcumin | Brain Edema | 4 | PM | 27979493 | 📋 | Curcumin Attenuates Blood-Brain Barrier Disruption After Subarachnoid Hemorrhage in Mice |
| Curcumin | Brain Edema | 2 | PM | 26686249 | 📋 | Curcumin by Down-Regulating NF-kB and Elevating Nrf2, Reduces Brain Edema and Neurological Dysfunction After Cerebral I/R |
| Curcumin | Brain Edema | 1 | PM | 26119880 | 📋 | Curcumin Attenuates Brain Edema in Mice With Intracerebral Hemorrhage Through Inhibition of AQP4 and AQP9 Expression |
| Curcumin | Brain Edema | 3 | PM | 14723822 | 📋 | [Protective Effect and Mechanism of Pretreatment With Curcumin on Infectious Brain Edema in Rats] |
| Curcumin | Brain Inflammation | 13 | PM | 35080289 | 📋 | Curcumin suppress inflammatory response in traumatic brain injury via p38/MAPK signaling pathway |
| Curcumin | Brain Inflammation | 2 | PM | 32502596 | 📋 | Curcumin Alleviates Neuroinflammation, Enhances Hippocampal Neurogenesis, and Improves Spatial Memory After Traumatic Brain Injury |
| Curcumin | Brain Inflammation | 19 | PM | 32225104 | 📋 | The Emerging Role of Curcumin in the Modulation of TLR-4 Signaling Pathway: Focus on Neuroprotective and Anti-Rheumatic Properties |
| Curcumin | Brain Inflammation | 1 | PM | 32175381 | 📋 | Protective Effects of Curcumin Against Neuroinflammation Induced by Aβ25-35 in Primary Rat Microglia: Modulation of High-Mobility Group Box 1, Toll-Like Receptor 4 and Receptor for Advanced Glycation End Products Expression |
| Curcumin | Brain Inflammation | 18 | PM | 27979493 | 📋 | Curcumin Attenuates Blood-Brain Barrier Disruption After Subarachnoid Hemorrhage in Mice |
| Curcumin | Brain Inflammation | 3 | PM | 27853890 | 📋 | Neuroprotective Potential of Curcumin in Combination With Piperine Against 6-hydroxy Dopamine Induced Motor Deficit and Neurochemical Alterations in Rats |
| Curcumin | Brain Inflammation | 5 | PM | 27026486 | 📋 | Curcumin Reduces Brain-Infiltrating T Lymphocytes After Intracerebral Hemorrhage in Mice |
| Curcumin | Brain Inflammation | 4 | PM | 26828892 | 📋 | Neuroprotective Activity of Curcumin in Combination With Piperine Against Quinolinic Acid Induced Neurodegeneration in Rats |
| Curcumin | Brain Inflammation | 9 | PM | 26639783 | 📋 | Curcumin Pretreatment Attenuates Inflammation and Mitochondrial Dysfunction in Experimental Stroke: The Possible Role of Sirt1 Signaling |
| Curcumin | Brain Inflammation | 7 | PM | 26190183 | 📋 | Curcumin Attenuates Inflammatory Response and Cognitive Deficits in Experimental Model of Chronic Epilepsy |
| Curcumin | Brain Inflammation | 16 | PM | 26047311 | 📋 | Microglial HO-1 Induction by Curcumin Provides Antioxidant, Antineuroinflammatory, and Glioprotective Effects |
| Curcumin | Brain Inflammation | 8 | PM | 25869755 | 📋 | Pretreatment With Curcumin Attenuates Anxiety While Strengthens Memory Performance After One Short Stress Experience in Male Rats |
| Curcumin | Brain Inflammation | 11 | PM | 24669820 | 📋 | Curcumin Attenuates Acute Inflammatory Injury by Inhibiting the TLR4/MyD88/NF-κB Signaling Pathway in Experimental Traumatic Brain Injury |
| Curcumin | Brain Inflammation | 10 | PM | 23932920 | 📋 | Curcumin Pretreatment Attenuates Brain Lesion Size and Improves Neurological Function Following Traumatic Brain Injury in the Rat |
| Curcumin | Brain Inflammation | 15 | PM | 20413894 | 📋 | PPARgamma Agonist Curcumin Reduces the Amyloid-Beta-Stimulated Inflammatory Responses in Primary Astrocytes |
| Curcumin | Brain Inflammation | 6 | PM | 18417733 | 📋 | Curcumin Structure-Function, Bioavailability, and Efficacy in Models of Neuroinflammation and Alzheimer's Disease |
| Curcumin | Brain Inflammation | 12 | PM | 17883952 | 📋 | Curcumin Attenuates the Release of Pro-Inflammatory Cytokines in Lipopolysaccharide-Stimulated BV2 Microglia |
| Curcumin | Brain Inflammation | 14 | PM | 15733321 | 📋 | Astrocyte Production of the Chemokine Macrophage Inflammatory protein-2 Is Inhibited by the Spice Principle Curcumin at the Level of Gene Transcription |
| Curcumin | Brain Inflammation | 17 | PM | 14634121 | 📋 | Curcumin Suppresses Janus kinase-STAT Inflammatory Signaling Through Activation of Src Homology 2 Domain-Containing Tyrosine Phosphatase 2 in Brain Microglia |
| Curcumin | Brain Injury | 1 | PM | 33396688 | 📋 | Curcumin Prevents Cerebellar Hypoplasia and Restores the Behavior in Hyperbilirubinemic Gunn Rat by a Pleiotropic Effect on the Molecular Effectors of Brain Damage |
| Curcumin | Brain Injury | 18 | PM | 20963814 | 📋 | Curcuminoids Rescue Long-Term Potentiation Impaired by Amyloid Peptide in Rat Hippocampal Slices |
| Curcumin | Brain Injury | 3 | PM | 20816821 | 📋 | A Pyrazole Curcumin Derivative Restores Membrane Homeostasis Disrupted After Brain Trauma |
| Curcumin | Brain Injury | 12 | PM | 20719539 | 📋 | Effect of Combined Treatment With Curcumin and Candesartan on Ischemic Brain Damage in Mice |
| Curcumin | Brain Injury | 8 | PM | 16770732 | 📋 | Immediate and Delayed Treatments With Curcumin Prevents Forebrain Ischemia-Induced Neuronal Damage and Oxidative Insult in the Rat Hippocampus |
| Curcumin | Brain Injury | 16 | PM | 15569404 | 📋 | Curcumin Protects Mitochondria From Oxidative Damage and Attenuates Apoptosis in Cortical Neurons |
| Curcumin | Brain Tumor | 7 | PM | 35178355 | 📋 | Curcumin in Combination with Other Adjunct Therapies for Brain Tumor Treatment: Existing Knowledge and Blueprint for Future Research |
| Curcumin | Brain Tumor | 6 | PM | 34408780 | 📋 | Curcumin Inhibits HGF-Induced EMT by Regulating c-MET-Dependent PI3K/Akt/mTOR Signaling Pathways in Meningioma |
| Curcumin | Brain Tumor | 1 | PM | 24975030 | 📋 | Artemisinin and Curcumin Inhibit Drosophila Brain Tumor, Prolong Life Span, and Restore Locomotor Activity |
| Curcumin | Brain Tumor | 3 | PM | 23192708 | 📋 | Curcumin Inhibits Telomerase and Induces Telomere Shortening and Apoptosis in Brain Tumour Cells |
| Curcumin | Brain Tumor | 5 | PM | 21903608 | 📋 | Combining Curcumin (Diferuloylmethane) and Heat Shock Protein Inhibition for Neurofibromatosis 2 Treatment: Analysis of Response and Resistance Pathways |
| Curcumin | Brain Tumor | 4 | PM | 19368804 | 📋 | Curcumin Blocks Brain Tumor Formation |
| Curcumin | Brain Tumor | 2 | PM | 16193380 | 📋 | Inhibition of Cellular Proliferation and Induction of Apoptosis by Curcumin in Human Malignant Astrocytoma Cell Lines |
| Curcumin | Carpal Tunnel Syndrome | 1 | PM | 38281082 | 📋 | Efficacy of topical curcumin on mild to moderate carpal tunnel syndrome: A randomized double-blind, placebo-controlled clinical trial |
| Curcumin | Chronic Pain | 1 | PM | 34451874 | 📋 | Mechanistic Insight into the Effects of Curcumin on Neuroinflammation-Driven Chronic Pain |
| Curcumin | Chronic Stress | 8 | PM | 35025528 | 📋 | Curcumin alleviates restraint stress-induced learning and memory deficit and activity via modulation of biochemical, morphology changes, and apoptosis in the prefrontal cortex and hippocampus |
| Curcumin | Chronic Stress | 7 | PM | 34950248 | 📋 | Curcumin Relieves Chronic Unpredictable Mild Stress-Induced Depression-Like Behavior through the PGC-1 α/FNDC5/BDNF Pathway |
| Curcumin | Chronic Stress | 6 | PM | 33161033 | 📋 | Adaptogenic Effects of Curcumin on Depression Induced by Moderate and Unpredictable Chronic Stress in Mice |
| Curcumin | Chronic Stress | 4 | PM | 30666189 | 📋 | Neuroprotective Effects of Curcumin on IL-1β-Induced Neuronal Apoptosis and Depression-Like Behaviors Caused by Chronic Stress in Rats |
| Curcumin | Chronic Stress | 9 | PM | 30268794 | 📋 | Antidepressant-like effect of salidroside and curcumin on the immunoreactivity of rats subjected to a chronic mild stress model |
| Curcumin | Chronic Stress | 1 | PM | 23099054 | 📋 | Piperine Potentiates the Protective Effects of Curcumin Against Chronic Unpredictable Stress-Induced Cognitive Impairment and Oxidative Damage in Mice |
| Curcumin | Chronic Stress | 3 | PM | 20920780 | 📋 | Curcumin Attenuates the Effects of Transport Stress on Serum Cortisol Concentration, Hippocampal NO Production, and BDNF Expression in the Pig |
| Curcumin | Chronic Stress | 5 | PM | 19540859 | 📋 | Curcumin Reverses Impaired Cognition and Neuronal Plasticity Induced by Chronic Stress |
| Curcumin | Chronic Stress | 2 | PM | 17022948 | 📋 | Curcumin Reverses the Effects of Chronic Stress on Behavior, the HPA Axis, BDNF Expression and Phosphorylation of CREB |
| Curcumin | Dementia | 1 | PM | 29614668 | 📋 | A Study of a Supplement Containing Huperzine A and Curcumin in Dementia Patients and Individuals With Mild Cognitive Impairment |
| Curcumin | Dementia | 4 | PM | 20369229 | 📋 | Involvement of PPAR-gamma in Curcumin-Mediated Beneficial Effects in Experimental Dementia |
| Curcumin | Dementia | 5 | PM | 20026275 | 📋 | Effect of Curcumin on Brain Insulin Receptors and Memory Functions in STZ (ICV) Induced Dementia Model of Rat |
| Curcumin | Dementia | 3 | PM | 19925811 | 📋 | Protective Effect of Curcumin Against Intracerebral Streptozotocin Induced Impairment in Memory and Cerebral Blood Flow |
| Curcumin | Dementia | 2 | PM | 16870699 | 📋 | Curry Consumption and Cognitive Function in the Elderly |
| Curcumin | Demyelinating Disease | 2 | PM | 33654147 | 📋 | Curcumin promotes oligodendrocyte differentiation and their protection against TNF-α through the activation of the nuclear receptor PPAR-γ |
| Curcumin | Demyelinating Disease | 1 | PM | 26211978 | 📋 | Polymerized Nano-Curcumin Attenuates Neurological Symptoms in EAE Model of Multiple Sclerosis Through Down Regulation of Inflammatory and Oxidative Processes and Enhancing Neuroprotection and Myelin Repair |
| Curcumin | Depression | 34 | PM | 37506423 | 📋 | The effect of curcumin on reserpine-induced depression-like behaviour in rats |
| Curcumin | Depression | 33 | PM | 37490124 | 📋 | Mechanistic insights into the anti-depressant effect of curcumin based on network pharmacology and experimental validation |
| Curcumin | Depression | 31 | PM | 35786408 | 📋 | Synergistic effects of Lacticaseibacillus rhamnosus GG, glutamine, and curcumin on chronic unpredictable mild stress-induced depression in a mouse model |
| Curcumin | Depression | 30 | PM | 35642797 | 📋 | Curcumin mitigates lipopolysaccharide-induced anxiety/depression-like behaviors, blood-brain barrier dysfunction and brain edema by decreasing cerebral oxidative stress in male rats |
| Curcumin | Depression | 29 | PM | 35129813 | 📋 | Potential Role of Curcumin for the Treatment of Major Depressive Disorder |
| Curcumin | Depression | 20 | PM | 34950248 | 📋 | Curcumin Relieves Chronic Unpredictable Mild Stress-Induced Depression-Like Behavior through the PGC-1 α/FNDC5/BDNF Pathway |
| Curcumin | Depression | 17 | PM | 34636389 | 📋 | Prophylactic treatment of curcumin in a rat model of depression by attenuating hippocampal synaptic loss |
| Curcumin | Depression | 28 | PM | 34409523 | 📋 | Therapeutic Potential of Curcumin in Reversing the Depression and Associated Pseudodementia via Modulating Stress Hormone, Hippocampal Neurotransmitters, and BDNF Levels in Rats |
| Curcumin | Depression | 27 | PM | 34331697 | 📋 | Effects of Curcumin on Depression and Anxiety: A Narrative Review of the Recent Clinical Data |
| Curcumin | Depression | 26 | PM | 33673739 | 📋 | A systematic review of the antidepressant effects of curcumin: Beyond monoamines theory |
| Curcumin | Depression | 25 | PM | 33589676 | 📋 | Creation of a gene expression portrait of depression and its application for identifying potential treatments |
| Curcumin | Depression | 24 | PM | 33329109 | 📋 | Curcumin in Depression: Potential Mechanisms of Action and Current Evidence-A Narrative Review |
| Curcumin | Depression | 23 | PM | 33161033 | 📋 | Adaptogenic Effects of Curcumin on Depression Induced by Moderate and Unpredictable Chronic Stress in Mice |
| Curcumin | Depression | 22 | PM | 33098686 | 📋 | Neuromodulatory effect of curcumin on catecholamine systems and inflammatory cytokines in ovariectomized female rats |
| Curcumin | Depression | 21 | PM | 33014280 | 📋 | Curcumin Attenuates Chronic Unpredictable Mild Stress-Induced Depressive-Like Behaviors via Restoring Changes in Oxidative Stress and the Activation of Nrf2 Signaling Pathway in Rats |
| Curcumin | Depression | 19 | PM | 31680089 | 📋 | Curcumin Lessens Unpredictable Chronic Mild Stress-Induced Depression and Memory Deficits by Modulating Oxidative Stress and Cholinergic Activity |
| Curcumin | Depression | 16 | PM | 30666189 | 📋 | Neuroprotective Effects of Curcumin on IL-1β-Induced Neuronal Apoptosis and Depression-Like Behaviors Caused by Chronic Stress in Rats |
| Curcumin | Depression | 14 | PM | 30551030 | 📋 | Curcumin Relieves Depressive-Like Behaviors via Inhibition of the NLRP3 Inflammasome and Kynurenine Pathway in Rats Suffering From Chronic Unpredictable Mild Stress |
| Curcumin | Depression | 32 | PM | 30268794 | 📋 | Antidepressant-like effect of salidroside and curcumin on the immunoreactivity of rats subjected to a chronic mild stress model |
| Curcumin | Depression | 3 | PM | 29327213 | 📋 | Add-on Treatment With Curcumin Has Antidepressive Effects in Thai Patients With Major Depression: Results of a Randomized Double-Blind Placebo-Controlled Study |
| Curcumin | Depression | 9 | PM | 28167853 | 📋 | Curcumin Alters Neural Plasticity and Viability of Intact Hippocampal Circuits and Attenuates Behavioral Despair and COX-2 Expression in Chronically Stressed Rats |
| Curcumin | Depression | 2 | PM | 26610378 | 📋 | The Role of Curcumin Administration in Patients With Major Depressive Disorder: Mini Meta-Analysis of Clinical Trials |
| Curcumin | Depression | 4 | PM | 26066335 | 📋 | Chronic Supplementation of Curcumin Enhances the Efficacy of Antidepressants in Major Depressive Disorder: A Randomized, Double-Blind, Placebo-Controlled Pilot Study |
| Curcumin | Depression | 6 | PM | 25523883 | 📋 | Curcumin and Major Depression: A Randomised, Double-Blind, Placebo-Controlled Trial Investigating the Potential of Peripheral Biomarkers to Predict Treatment Response and Antidepressant Mechanisms of Change |
| Curcumin | Depression | 8 | PM | 25091591 | 📋 | Investigation of the Efficacy of Adjunctive Therapy With Bioavailability-Boosted Curcuminoids in Major Depressive Disorder |
| Curcumin | Depression | 7 | PM | 25046624 | 📋 | Curcumin for the Treatment of Major Depression: A Randomised, Double-Blind, Placebo Controlled Study |
| Curcumin | Depression | 10 | PM | 24297305 | 📋 | Chronic Curcumin Treatment Normalizes Depression-Like Behaviors in Mice With Mononeuropathy: Involvement of Supraspinal Serotonergic System and GABAA Receptor |
| Curcumin | Depression | 5 | PM | 23832433 | 📋 | Efficacy and Safety of Curcumin in Major Depressive Disorder: A Randomized Controlled Trial |
| Curcumin | Depression | 12 | PM | 21928724 | 📋 | Evaluation of Antidepressant Like Activity of Curcumin and Its Combination With Fluoxetine and Imipramine: An Acute and Chronic Study |
| Curcumin | Depression | 18 | PM | 19882093 | 📋 | Potentials of Curcumin as an Antidepressant |
| Curcumin | Depression | 1 | PM | 19000708 | 📋 | Anti-depressant Like Effect of Curcumin and Its Combination With Piperine in Unpredictable Chronic Stress-Induced Behavioral, Biochemical and Neurochemical Changes |
| Curcumin | Depression | 13 | PM | 18766332 | 📋 | Antidepressant Activity of Curcumin: Involvement of Serotonin and Dopamine System |
| Curcumin | Depression | 11 | PM | 16171853 | 📋 | Antidepressant Effects of Curcumin in the Forced Swim Test and Olfactory Bulbectomy Models of Depression in Rats |
| Curcumin | Depression | 15 | PM | 15987635 | 📋 | The Effects of Curcumin on Depressive-Like Behaviors in Mice |
| Curcumin | Diabetic Encephalopathy | 10 | PM | 36221434 | 📋 | Curcumin protects PC12 cells from a high glucose-induced inflammatory response by regulating the miR-218-5p/TLR4 axis |
| Curcumin | Diabetic Encephalopathy | 9 | PM | 33602334 | 📋 | Curcumin and its analog alleviate diabetes-induced damages by regulating inflammation and oxidative stress in brain of diabetic rats |
| Curcumin | Diabetic Encephalopathy | 1 | PM | 32375323 | 📋 | Exercise and Curcumin in Combination Improves Cognitive Function and Attenuates ER Stress in Diabetic Rats |
| Curcumin | Diabetic Encephalopathy | 8 | PM | 26274972 | 📋 | Diet-Induced Cognitive Deficits: The Role of Fat and Sugar, Potential Mechanisms and Nutritional Interventions |
| Curcumin | Diabetic Encephalopathy | 5 | PM | 20637830 | 📋 | Role of Curcumin in the Prevention of Cholinergic Mediated Cortical Dysfunctions in Streptozotocin-Induced Diabetic Rats |
| Curcumin | Diabetic Encephalopathy | 4 | PM | 20513244 | 📋 | Curcumin Modulates Dopaminergic Receptor, CREB and Phospholipase C Gene Expression in the Cerebral Cortex and Cerebellum of Streptozotocin Induced Diabetic Rats |
| Curcumin | Diabetic Encephalopathy | 7 | PM | 19804785 | 📋 | Neuroprotective Role of Curcumin in the Cerebellum of Streptozotocin-Induced Diabetic Rats |
| Curcumin | Diabetic Encephalopathy | 2 | PM | 19234767 | 📋 | Curcumin Ameliorates Impaired insulin/IGF Signalling and Memory Deficit in a Streptozotocin-Treated Rat Model |
| Curcumin | Diabetic Encephalopathy | 6 | PM | 19031318 | 📋 | Curcuminoids Modulates Oxidative Damage and Mitochondrial Dysfunction in Diabetic Rat Brain |
| Curcumin | Diabetic Encephalopathy | 3 | PM | 17822693 | 📋 | Curcumin Attenuates Diabetic Encephalopathy in Rats: Behavioral and Biochemical Evidences |
| Curcumin | Diabetic Neuropathy | 13 | PM | 37255806 | 📋 | Evaluation of curcumin effect on Il6, Sirt1, TNFα and NFkB expression of liver tissues in diabetic mice with STZ |
| Curcumin | Diabetic Neuropathy | 12 | PM | 36968023 | 📋 | Suppression of neuronal apoptosis and glial activation with modulation of Nrf2/HO-1 and NF-kB signaling by curcumin in streptozotocin-induced diabetic spinal cord central neuropathy |
| Curcumin | Diabetic Neuropathy | 11 | PM | 35868051 | 📋 | Curcumin protect Schwann cells from inflammation response and apoptosis induced by high glucose through the NF-κB pathway |
| Curcumin | Diabetic Neuropathy | 10 | PM | 35538560 | 📋 | Curcumin ameliorates the experimental diabetic peripheral neuropathy through promotion of NGF expression in rats |
| Curcumin | Diabetic Neuropathy | 9 | PM | 33581265 | 📋 | How Curcumin Affects Hyperglycemia-Induced Optic Nerve Damage: A Short Review |
| Curcumin | Diabetic Neuropathy | 8 | PM | 33532012 | 📋 | Effects of Curcumin Treatment in a Diabetic Neuropathic Pain Model of Rats: Involvement of c-Jun N-Terminal Kinase Located in the Astrocytes and Neurons of the Dorsal Root Ganglion |
| Curcumin | Diabetic Neuropathy | 7 | PM | 27215022 | 📋 | Effects of Curcumin on Sodium Currents of Dorsal Root Ganglion Neurons in Type 2 Diabetic Neuropathic Pain Rats |
| Curcumin | Diabetic Neuropathy | 4 | PM | 26398443 | 📋 | Effects of Curcumin and Captopril on the Functions of Kidney and Nerve in Streptozotocin-Induced Diabetic Rats: Role of Angiotensin Converting Enzyme 1 |
| Curcumin | Diabetic Neuropathy | 5 | PM | 26282904 | 📋 | Effects of Curcumin on TTX-R Sodium Currents of Dorsal Root Ganglion Neurons in Type 2 Diabetic Rats With Diabetic Neuropathic Pain |
| Curcumin | Diabetic Neuropathy | 3 | PM | 24315931 | 📋 | Effect of Curcumin on Diabetic Peripheral Neuropathic Pain: Possible Involvement of Opioid System |
| Curcumin | Diabetic Neuropathy | 1 | PM | 23471081 | 📋 | Curcumin Attenuates Diabetic Neuropathic Pain by Downregulating TNF-α in a Rat Model |
| Curcumin | Diabetic Neuropathy | 6 | PM | 17199240 | 📋 | Effect of Insulin and Its Combination With Resveratrol or Curcumin in Attenuation of Diabetic Neuropathic Pain: Participation of Nitric Oxide and TNF-alpha |
| Curcumin | Diabetic Neuropathy | 2 | PM | 16584726 | 📋 | Curcumin Attenuates Thermal Hyperalgesia in a Diabetic Mouse Model of Neuropathic Pain |
| Curcumin | Down Syndrome | 1 | PM | 32729926 | 📋 | Prenatal, but not Postnatal, Curcumin Administration Rescues Neuromorphological and Cognitive Alterations in Ts65Dn Down Syndrome Mice |
| Curcumin | Encephalitis | 2 | PM | 24780919 | 📋 | Antioxidants: Potential Antiviral Agents for Japanese Encephalitis Virus Infection |
| Curcumin | Encephalitis | 3 | PM | 19434500 | 📋 | Curcumin Protects Neuronal Cells From Japanese Encephalitis Virus-Mediated Cell Death and Also Inhibits Infective Viral Particle Formation by Dysregulation of Ubiquitin-Proteasome System |
| Curcumin | Encephalitis | 1 | PM | 19000058 | 📋 | Oxidative Stress and Hippocampus in a Low-Grade Hepatic Encephalopathy Model: Protective Effects of Curcumin |
| Curcumin | Encephalomyelitis | 1 | PM | 12055272 | 📋 | Curcumin Inhibits Experimental Allergic Encephalomyelitis by Blocking IL-12 Signaling Through Janus kinase-STAT Pathway in T Lymphocytes |
| Curcumin | Epilepsy | 19 | PM | 38826549 | 📋 | Identification of Curcumin Targets in the Brain of Epileptic Mice Using DARTS |
| Curcumin | Epilepsy | 18 | PM | 37765031 | 📋 | Ameliorative Effect of Ethanolic Extract of Moringa oleifera Leaves in Combination with Curcumin against PTZ-Induced Kindled Epilepsy in Rats: In Vivo and In Silico |
| Curcumin | Epilepsy | 17 | PM | 36130709 | 📋 | PET Imaging and Neurohistochemistry Reveal that Curcumin Attenuates Brain Hypometabolism and Hippocampal Damage induced by Status Epilepticus in Rats |
| Curcumin | Epilepsy | 16 | PM | 34331701 | 📋 | Curcumin: A Review of Its Effects on Epilepsy |
| Curcumin | Epilepsy | 15 | PM | 32803504 | 📋 | Ameliorative effect of curcumin on altered expression of CACNA1A and GABRD in the pathogenesis of FeCl 3-induced epilepsy |
| Curcumin | Epilepsy | 13 | PM | 30747999 | 📋 | Curcumin Reduces Development of Seizurelike Events in the Hippocampal-Entorhinal Cortex Slice Culture Model for Epileptogenesis |
| Curcumin | Epilepsy | 12 | PM | 28177687 | 📋 | Curcumin Protects Neuronal Cells Against Status-Epilepticus-Induced Hippocampal Damage Through Induction of Autophagy and Inhibition of Necroptosis |
| Curcumin | Epilepsy | 11 | PM | 26415768 | 📋 | Protection Against Cognitive Impairment and Modification of Epileptogenesis With Curcumin in a Post-Status Epilepticus Model of Temporal Lobe Epilepsy |
| Curcumin | Epilepsy | 10 | PM | 26406082 | 📋 | The Involvement of Neuronal Nitric Oxide Synthase in the Anti-Epileptic Action of Curcumin on Pentylenetetrazol-Kindled Rats |
| Curcumin | Epilepsy | 4 | PM | 26190183 | 📋 | Curcumin Attenuates Inflammatory Response and Cognitive Deficits in Experimental Model of Chronic Epilepsy |
| Curcumin | Epilepsy | 8 | PM | 25117510 | 📋 | Curcumin Supplementation Improves Mitochondrial and Behavioral Deficits in Experimental Model of Chronic Epilepsy |
| Curcumin | Epilepsy | 1 | PM | 24004105 | 📋 | Antiepileptogenic Effect of Curcumin on Kainate-Induced Model of Temporal Lobe Epilepsy |
| Curcumin | Epilepsy | 9 | PM | 22044441 | 📋 | Liposomal Formulation of Curcumin Attenuates Seizures in Different Experimental Models of Epilepsy in Mice |
| Curcumin | Epilepsy | 7 | PM | 20840851 | 📋 | Protective Effect of Curcumin Against Seizures and Cognitive Impairment in a Pentylenetetrazole-Kindled Epileptic Rat Model |
| Curcumin | Epilepsy | 6 | PM | 20508869 | 📋 | Antioxidant Potential of Curcumin Against Oxidative Insult Induced by Pentylenetetrazol in Epileptic Rats |
| Curcumin | Epilepsy | 3 | PM | 19810575 | 📋 | Protective Effect of Curcumin Against Kainic Acid Induced Seizures and Oxidative Stress in Rats |
| Curcumin | Epilepsy | 5 | PM | 19100339 | 📋 | Curcumin Protects Against Electrobehavioral Progression of Seizures in the Iron-Induced Experimental Model of Epileptogenesis |
| Curcumin | Epilepsy | 2 | PM | 18661468 | 📋 | Curcumin Has Anticonvulsant Activity on Increasing Current Electroshock Seizures in Mice |
| Curcumin | Epilepsy | 14 | PM | 16266725 | 📋 | Prevention of Kainic Acid-Induced Changes in Nitric Oxide Level and Neuronal Cell Damage in the Rat Hippocampus by Manganese Complexes of Curcumin and Diacetylcurcumin |
| Curcumin | Febrile Seizure | 1 | PM | 32585605 | 📋 | Protective Effects of Maternal Administration of Curcumin and Hesperidin in the Rat Offspring Following Repeated Febrile Seizure: Role of Inflammation and TLR4 |
| Curcumin | Glioblastoma | 17 | PM | 36714540 | 📋 | Combined treatments with AZD5363, AZD8542, curcumin or resveratrol induce death of human glioblastoma cells by suppressing the PI3K/AKT and SHH signaling pathways |
| Curcumin | Glioblastoma | 32 | PM | 35446963 | 📋 | Interaction of curcumin with glioblastoma cells via high and low linear energy transfer radiation therapy inducing radiosensitization effects |
| Curcumin | Glioblastoma | 31 | PM | 34234410 | 📋 | Study on the Inhibitory Effect of Curcumin on GBM and Its Potential Mechanism |
| Curcumin | Glioblastoma | 30 | PM | 33813391 | 📋 | Demethoxycurcumin Suppresses Proliferation, Migration, and Invasion of Human Brain Glioblastoma Multiforme GBM 8401 Cells via PI3K/Akt Pathway |
| Curcumin | Glioblastoma | 29 | PM | 33809462 | 📋 | Anticancer Mechanism of Curcumin on Human Glioblastoma |
| Curcumin | Glioblastoma | 28 | PM | 33322413 | 📋 | Antitumor Activity of Curcumin in Glioblastoma |
| Curcumin | Glioblastoma | 27 | PM | 33092261 | 📋 | The Multi-Faceted Effect of Curcumin in Glioblastoma from Rescuing Cell Clearance to Autophagy-Independent Effects |
| Curcumin | Glioblastoma | 26 | PM | 32575632 | 📋 | Validation of Enhancing Effects of Curcumin on Radiotherapy With F98/ FGT Glioblastoma-Bearing Rat Model |
| Curcumin | Glioblastoma | 16 | PM | 32445778 | 📋 | Curcumin Suppress Glioblastoma Cell Proliferation by p-AKT/mTOR Pathway and Increased the PTEN Expression |
| Curcumin | Glioblastoma | 1 | PM | 32172947 | 📋 | Curcumin-induced Cell Death Depends on the Level of Autophagic Flux in A172 and U87MG Human Glioblastoma Cells |
| Curcumin | Glioblastoma | 2 | PM | 31841506 | 📋 | Combination Treatment of Berberine and Solid Lipid Curcumin Particles Increased Cell Death and Inhibited PI3K/Akt/mTOR Pathway of Human Cultured Glioblastoma Cells More Effectively Than Did Individual Treatments |
| Curcumin | Glioblastoma | 23 | PM | 29969678 | 📋 | Evaluation of Targeted Curcumin (CUR) Loaded PLGA Nanoparticles for in Vitro Photodynamic Therapy on Human Glioblastoma Cell Line |
| Curcumin | Glioblastoma | 14 | PM | 29723631 | 📋 | Paraptosis in Human Glioblastoma Cell Line Induced by Curcumin |
| Curcumin | Glioblastoma | 9 | PM | 28260885 | 📋 | The Functional Curcumin Liposomes Induce Apoptosis in C6 Glioblastoma Cells and C6 Glioblastoma Stem Cells in Vitro and in Animals |
| Curcumin | Glioblastoma | 18 | PM | 28160777 | 📋 | Curcumin Decreases Malignant Characteristics of Glioblastoma Stem Cells via Induction of Reactive Oxygen Species |
| Curcumin | Glioblastoma | 5 | PM | 27543754 | 📋 | Curcumin Changes the Polarity of Tumor-Associated Microglia and Eliminates Glioblastoma |
| Curcumin | Glioblastoma | 4 | PM | 27340742 | 📋 | Intratumoral Concentrations and Effects of Orally Administered Micellar Curcuminoids in Glioblastoma Patients |
| Curcumin | Glioblastoma | 25 | PM | 26763536 | 📋 | Pharmacological Inhibition of Lipid Droplet Formation Enhances the Effectiveness of Curcumin in Glioblastoma |
| Curcumin | Glioblastoma | 24 | PM | 26748069 | 📋 | Prospective of Curcumin, a Pleiotropic Signalling Molecule From Curcuma Longa in the Treatment of Glioblastoma |
| Curcumin | Glioblastoma | 21 | PM | 26637846 | 📋 | Curcumin for the Treatment of Glioblastoma |
| Curcumin | Glioblastoma | 12 | PM | 26364505 | 📋 | Modulatory Effects of Curcumin and Tyrphostins (AG494 and AG1478) on Growth Regulation and Viability of LN229 Human Brain Cancer Cells |
| Curcumin | Glioblastoma | 11 | PM | 26239619 | 📋 | Induction of microRNA-146a Is Involved in Curcumin-Mediated Enhancement of Temozolomide Cytotoxicity Against Human Glioblastoma |
| Curcumin | Glioblastoma | 6 | PM | 25050915 | 📋 | Curcumin Sensitizes Glioblastoma to Temozolomide by Simultaneously Generating ROS and Disrupting AKT/mTOR Signaling |
| Curcumin | Glioblastoma | 22 | PM | 23621850 | 📋 | Epigenetic Reactivation of RANK in Glioblastoma Cells by Curcumin: Involvement of STAT3 Inhibition |
| Curcumin | Glioblastoma | 10 | PM | 22842701 | 📋 | Induction of Apoptosis and Reduction of MMP Gene Expression in the U373 Cell Line by Polyphenolics in Aronia Melanocarpa and by Curcumin |
| Curcumin | Glioblastoma | 8 | PM | 21775121 | 📋 | The Curry Spice Curcumin Selectively Inhibits Cancer Cells Growth in Vitro and in Preclinical Model of Glioblastoma |
| Curcumin | Glioblastoma | 20 | PM | 20822178 | 📋 | Curcuminoids Suppress the Growth and Induce Apoptosis Through caspase-3-dependent Pathways in Glioblastoma Multiforme (GBM) 8401 Cells |
| Curcumin | Glioblastoma | 13 | PM | 20596601 | 📋 | The Anti-Cancer Efficacy of Curcumin Scrutinized Through Core Signaling Pathways in Glioblastoma |
| Curcumin | Glioblastoma | 7 | PM | 20087857 | 📋 | Curcumin Inhibits Tumor Growth and Angiogenesis in Glioblastoma Xenografts |
| Curcumin | Glioblastoma | 19 | PM | 17596214 | 📋 | Curcumin Suppresses Growth and Chemoresistance of Human Glioblastoma Cells via AP-1 and NFkappaB Transcription Factors |
| Curcumin | Glioblastoma | 15 | PM | 17562168 | 📋 | Curcumin Suppressed Anti-Apoptotic Signals and Activated Cysteine Proteases for Apoptosis in Human Malignant Glioblastoma U87MG Cells |
| Curcumin | Glioblastoma | 3 | PM | 16949208 | 📋 | Curcumin Activated Both Receptor-Mediated and Mitochondria-Mediated Proteolytic Pathways for Apoptosis in Human Glioblastoma T98G Cells |
| Curcumin | Glioma | 25 | PM | 38397870 | 📋 | Action of Curcumin on Glioblastoma Growth: A Systematic Review with Meta-Analysis of Animal Model Studies |
| Curcumin | Glioma | 24 | PM | 36238646 | 📋 | Curcumin Enhanced Ionizing Radiation-Induced Immunogenic Cell Death in Glioma Cells through Endoplasmic Reticulum Stress Signaling Pathways |
| Curcumin | Glioma | 23 | PM | 35790698 | 📋 | Review on the Therapeutic Potential of Curcumin and its Derivatives on Glioma Biology |
| Curcumin | Glioma | 17 | PM | 34829791 | 📋 | Curcumin and Radiotherapy Exert Synergistic Anti-Glioma Effect In Vitro |
| Curcumin | Glioma | 22 | PM | 34169637 | 📋 | Curcumin inhibits adverse psychological stress-induced proliferation and invasion of glioma cells via down-regulating the ERK/MAPK pathway |
| Curcumin | Glioma | 21 | PM | 33574907 | 📋 | HSP60 participates in the anti-glioma effects of curcumin |
| Curcumin | Glioma | 20 | PM | 33231085 | 📋 | Curcumin combined with low-intensity ultrasound suppresses the growth of glioma cells via inhibition of the AKT pathway |
| Curcumin | Glioma | 14 | PM | 31511210 | 📋 | [Curcumin Suppresses Invasiveness and Migration of Human Glioma Cells in Vitro by Inhibiting HDGF/β-catenin Complex] |
| Curcumin | Glioma | 4 | PM | 29588587 | 📋 | Targeted Therapy of Intracranial Glioma Model Mice With Curcumin Nanoliposomes |
| Curcumin | Glioma | 8 | PM | 28627598 | 📋 | Curcumin Exerts Its Tumor Suppressive Function via Inhibition of NEDD4 Oncoprotein in Glioma Cancer Cells |
| Curcumin | Glioma | 16 | PM | 27680947 | 📋 | The Circadian Clock Modulates Anti-Cancer Properties of Curcumin |
| Curcumin | Glioma | 18 | PM | 27373979 | 📋 | Cathepsin L Knockdown Enhances Curcumin-Mediated Inhibition of Growth, Migration, and Invasion of Glioma Cells |
| Curcumin | Glioma | 1 | PM | 27354801 | 📋 | Biodegradable Micelles Enhance the Antiglioma Activity of Curcumin in Vitro and in Vivo |
| Curcumin | Glioma | 19 | PM | 26046466 | 📋 | Curcumin Suppresses Cell Growth and Invasion and Induces Apoptosis by Down-Regulation of Skp2 Pathway in Glioma Cells |
| Curcumin | Glioma | 9 | PM | 22192169 | 📋 | Curcumin Promotes Differentiation of Glioma-Initiating Cells by Inducing Autophagy |
| Curcumin | Glioma | 3 | PM | 21138870 | 📋 | Dietary Curcumin Attenuates Glioma Growth in a Syngeneic Mouse Model by Inhibition of the JAK1,2/STAT3 Signaling Pathway |
| Curcumin | Glioma | 7 | PM | 20840775 | 📋 | The Nontoxic Natural Compound Curcumin Exerts Anti-Proliferative, Anti-Migratory, and Anti-Invasive Properties Against Malignant Gliomas |
| Curcumin | Glioma | 5 | PM | 20089354 | 📋 | Curcumin Inhibits the Side Population (SP) Phenotype of the Rat C6 Glioma Cell Line: Towards Targeting of Cancer Stem Cells With Phytochemicals |
| Curcumin | Glioma | 15 | PM | 19422808 | 📋 | Demethoxycurcumin Induces Bcl-2 Mediated G2/M Arrest and Apoptosis in Human Glioma U87 Cells |
| Curcumin | Glioma | 10 | PM | 17594054 | 📋 | Curcumin Induces G2/M Cell Cycle Arrest in a p53-dependent Manner and Upregulates ING4 Expression in Human Glioma |
| Curcumin | Glioma | 2 | PM | 17395690 | 📋 | Evidence That Curcumin Suppresses the Growth of Malignant Gliomas in Vitro and in Vivo Through Induction of Autophagy: Role of Akt and Extracellular Signal-Regulated Kinase Signaling Pathways |
| Curcumin | Glioma | 11 | PM | 16777101 | 📋 | Silencing of the Human Microsomal glucose-6-phosphate Translocase Induces Glioma Cell Death: Potential New Anticancer Target for Curcumin |
| Curcumin | Glioma | 6 | PM | 16646663 | 📋 | Curcumin-induced Histone Hypoacetylation Enhances caspase-3-dependent Glioma Cell Death and Neurogenesis of Neural Progenitor Cells |
| Curcumin | Glioma | 13 | PM | 16198311 | 📋 | Curcumin Is a Potent Broad Spectrum Inhibitor of Matrix Metalloproteinase Gene Expression in Human Astroglioma Cells |
| Curcumin | Glioma | 12 | PM | 16102725 | 📋 | Curcumin Suppresses Phorbol Ester-Induced Matrix metalloproteinase-9 Expression by Inhibiting the PKC to MAPK Signaling Pathways in Human Astroglioma Cells |
| Curcumin | Hepatic Encephalopathy | 2 | PM | 34630953 | 📋 | Evaluation of the protective effect of curcumin on encephalopathy caused by intrahepatic and extrahepatic damage in male rats |
| Curcumin | Hepatic Encephalopathy | 1 | PM | 32761362 | 📋 | Curcumin prevents cognitive deficits in the bile duct ligated rats |
| Curcumin | HIV/AIDS | 18 | PM | 37314412 | 📋 | Curcuma Longa Induces the Transcription Factor FOXP3 to Downregulate Human Chemokine CCR5 Expression and Inhibit HIV-1 Infection |
| Curcumin | HIV/AIDS | 17 | PM | 26404185 | 📋 | Curcumin and Its Analogues: A Potential Natural Compound Against HIV Infection and AIDS |
| Curcumin | HIV/AIDS | 6 | PM | 26294283 | 📋 | Curcumin Increases HSP70 Expression in Primary Rat Cortical Neuronal Apoptosis Induced by gp120 V3 Loop Peptide |
| Curcumin | HIV/AIDS | 5 | PM | 26199609 | 📋 | Curcumin Improves Synaptic Plasticity Impairment Induced by HIV-1gp120 V3 Loop |
| Curcumin | HIV/AIDS | 3 | PM | 25856395 | 📋 | The Anti-Inflammatory Activity of Curcumin Protects the Genital Mucosal Epithelial Barrier From Disruption and Blocks Replication of HIV-1 and HSV-2 |
| Curcumin | HIV/AIDS | 7 | PM | 23936448 | 📋 | Curcumin Protects Microglia and Primary Rat Cortical Neurons Against HIV-1 gp120-mediated Inflammation and Apoptosis |
| Curcumin | HIV/AIDS | 4 | PM | 19345695 | 📋 | Curcumin Improves Spatial Memory Impairment Induced by Human Immunodeficiency Virus Type 1 Glycoprotein 120 V3 Loop Peptide in Rats |
| Curcumin | HIV/AIDS | 2 | PM | 19051018 | 📋 | Treatment of HIV-associated Diarrhea With Curcumin |
| Curcumin | HIV/AIDS | 9 | PM | 18175040 | 📋 | Two Immunomodulators, Curcumin and Sulfasalazine, Enhance IDV Antiretroviral Activity in HIV-1 Persistently Infected Cells |
| Curcumin | HIV/AIDS | 14 | PM | 15950462 | 📋 | Active Site Binding Modes of Curcumin in HIV-1 Protease and Integrase |
| Curcumin | HIV/AIDS | 15 | PM | 15383533 | 📋 | Curcumin, a Novel p300/CREB-binding Protein-Specific Inhibitor of Acetyltransferase, Represses the Acetylation of Histone/Nonhistone Proteins and Histone Acetyltransferase-Dependent Chromatin Transcription |
| Curcumin | HIV/AIDS | 12 | PM | 14674708 | 📋 | Curcumin Inhibits Ultraviolet Light Induced Human Immunodeficiency Virus Gene Expression |
| Curcumin | HIV/AIDS | 13 | PM | 14561543 | 📋 | Curcumin: A Potential Vaginal Contraceptive |
| Curcumin | HIV/AIDS | 10 | PM | 9561563 | 📋 | Curcumin and Curcumin Derivatives Inhibit Tat-mediated Transactivation of Type 1 Human Immunodeficiency Virus Long Terminal Repeat |
| Curcumin | HIV/AIDS | 16 | PM | 8691490 | 📋 | Curcumin--a Natural Herb With anti-HIV Activity |
| Curcumin | HIV/AIDS | 8 | PM | 8446597 | 📋 | Three Inhibitors of Type 1 Human Immunodeficiency Virus Long Terminal Repeat-Directed Gene Expression and Virus Replication |
| Curcumin | HIV/AIDS | 1 | PM | 8087563 | 📋 | Inhibition of the HIV-1 and HIV-2 Proteases by Curcumin and Curcumin Boron Complexes |
| Curcumin | HIV/AIDS | 11 | PM | 7748198 | 📋 | Inhibition of Human Immunodeficiency Virus type-1 Integrase by Curcumin |
| Curcumin | Huntington's Disease | 5 | PM | 37781812 | 📋 | Amendment of Altered Immune Response by Curcumin in Drosophila Model of Huntington's Disease |
| Curcumin | Huntington's Disease | 4 | PM | 34743577 | 📋 | Management of altered metabolic activity in Drosophila model of Huntington's disease by curcumin |
| Curcumin | Huntington's Disease | 3 | PM | 33334207 | 📋 | Melatonin and curcumin reestablish disturbed circadian gene expressions and restore locomotion ability and eclosion behavior in Drosophila model of Huntington's disease |
| Curcumin | Huntington's Disease | 2 | PM | 26728250 | 📋 | Curcumin Modulates Cell Death and Is Protective in Huntington's Disease Model |
| Curcumin | Huntington's Disease | 1 | PM | 26160706 | 📋 | Piperine Enhances the Protective Effect of Curcumin Against 3-NP Induced Neurotoxicity: Possible Neurotransmitters Modulation Mechanism |
| Curcumin | Hydrocephalus | 1 | PM | 35421860 | 📋 | Curcumin Attenuates Hydrocephalus via Activation of E2F Transcription Factor 4 |
| Curcumin | Hyperalgesia | 4 | PM | 26744842 | 📋 | PLGA-Curcumin Attenuates Opioid-Induced Hyperalgesia and Inhibits Spinal CaMKIIα |
| Curcumin | Hyperalgesia | 3 | PM | 25479948 | 📋 | Curcumin Attenuates CFA Induced Thermal Hyperalgesia by Modulation of Antioxidant Enzymes and Down Regulation of TNF-α, IL-1β and IL-6 |
| Curcumin | Hyperalgesia | 2 | PM | 20040737 | 📋 | Curcumin Produces an Antihyperalgesic Effect via Antagonism of TRPV1 |
| Curcumin | Hyperalgesia | 1 | PM | 16584726 | 📋 | Curcumin Attenuates Thermal Hyperalgesia in a Diabetic Mouse Model of Neuropathic Pain |
| Curcumin | Intracerebral Hemorrhage | 5 | PM | 35571134 | 📋 | Curcumin Restrains Oxidative Stress of After Intracerebral Hemorrhage in Rat by Activating the Nrf2/HO-1 Pathway |
| Curcumin | Intracerebral Hemorrhage | 4 | PM | 35381181 | 📋 | Curcumin attenuates intracerebral hemorrhage-induced neuronal apoptosis and neuroinflammation by suppressing the JAK1/STAT1 pathway |
| Curcumin | Intracerebral Hemorrhage | 3 | PM | 27026486 | 📋 | Curcumin Reduces Brain-Infiltrating T Lymphocytes After Intracerebral Hemorrhage in Mice |
| Curcumin | Intracerebral Hemorrhage | 1 | PM | 26119880 | 📋 | Curcumin Attenuates Brain Edema in Mice With Intracerebral Hemorrhage Through Inhibition of AQP4 and AQP9 Expression |
| Curcumin | Intracerebral Hemorrhage | 2 | PM | 12578124 | 📋 | Differential Regulation of Cytokines and Transcription Factors in Liver by Curcumin Following Hemorrhage/Resuscitation |
| Curcumin | Ischemic Stroke | 7 | PM | 38082237 | 📋 | The effects of curcumin-piperine supplementation on inflammatory, oxidative stress and metabolic indices in patients with ischemic stroke in the rehabilitation phase: a randomized controlled trial |
| Curcumin | Ischemic Stroke | 6 | PM | 37915409 | 📋 | Pharmacological intervention of curcumin via the NLRP3 inflammasome in ischemic stroke |
| Curcumin | Ischemic Stroke | 5 | PM | 36598916 | 📋 | Curcumin's mechanism of action against ischemic stroke: A network pharmacology and molecular dynamics study |
| Curcumin | Ischemic Stroke | 4 | PM | 35559238 | 📋 | Mechanisms Underlying Curcumin-Induced Neuroprotection in Cerebral Ischemia |
| Curcumin | Ischemic Stroke | 3 | PM | 34630845 | 📋 | Curcumin Ameliorates White Matter Injury after Ischemic Stroke by Inhibiting Microglia/Macrophage Pyroptosis through NF- κ B Suppression and NLRP3 Inflammasome Inhibition |
| Curcumin | Ischemic Stroke | 2 | PM | 34055082 | 📋 | Curcumin ameliorates ischemic stroke injury in rats by protecting the integrity of the blood-brain barrier |
| Curcumin | Ischemic Stroke | 1 | PM | 25878600 | 📋 | Curcumin Pretreatment and Post-Treatment Both Improve the Antioxidative Ability of Neurons With Oxygen-Glucose Deprivation |
| Curcumin | Lewy Body Dementia | 1 | PM | 29614668 | 📋 | A Study of a Supplement Containing Huperzine A and Curcumin in Dementia Patients and Individuals With Mild Cognitive Impairment |
| Curcumin | Medulloblastoma | 1 | PM | 20332461 | 📋 | Curcumin (Diferuloylmethane) Induces Apoptosis and Blocks Migration of Human Medulloblastoma Cells |
| Curcumin | Medulloblastoma | 2 | PM | 20025076 | 📋 | Curcumin Inhibits the Sonic Hedgehog Signaling Pathway and Triggers Apoptosis in Medulloblastoma Cells |
| Curcumin | Meningitis | 1 | PM | 22053741 | 📋 | Curcumin Alleviates Eosinophilic Meningitis Through Reduction of Eosinophil Count Following Albendazole Treatment Against Angiostrongylus Cantonensis in Mice |
| Curcumin | Meningitis | 2 | PM | 17381860 | 📋 | Efficacy of Curcumin Therapy Against Angiostrongylus Cantonensis-Induced Eosinophilic Meningitis |
| Curcumin | Migraine | 6 | PM | 37216708 | 📋 | The impact of curcumin on migraine: A comprehensive review |
| Curcumin | Migraine | 5 | PM | 35070194 | 📋 | Effects of Curcumin Supplementation on Clinical Features and Inflammation, in Migraine Patients: A Double-Blind Controlled, Placebo Randomized Clinical Trial |
| Curcumin | Migraine | 4 | PM | 32727335 | 📋 | Anti-Neuroinflammatory Properties of n-3 Fatty Acids and Nano-Curcumin on Migraine Patients, from Cellular to Clinical Insight: A Randomized, Double Blind, and Placebo-Controlled Trial |
| Curcumin | Migraine | 2 | PM | 31287810 | 📋 | Liposomal Curcumin Enhances the Effect of Naproxen in a Rat Model of Migraine |
| Curcumin | Migraine | 3 | PM | 31241007 | 📋 | The Synergistic Effects of Nano-Curcumin and Coenzyme Q10 Supplementation in Migraine Prophylaxis: A Randomized, Placebo-Controlled, Double-Blind Trial |
| Curcumin | Migraine | 1 | PM | 28478481 | 📋 | The Synergistic Effects of ω-3 Fatty Acids and Nano-Curcumin Supplementation on Tumor Necrosis Factor (TNF)-α Gene Expression and Serum Level in Migraine Patients |
| Curcumin | Multiple Sclerosis | 16 | PM | 38566376 | 📋 | Immunoregulatory Effects of the Active Form of Vitamin D (Calcitriol), Individually and in Combination with Curcumin, on Peripheral Blood Mononuclear Cells (PBMCs) of Multiple Sclerosis (MS) Patients |
| Curcumin | Multiple Sclerosis | 15 | PM | 38477954 | 📋 | Curcumin and Its Semisynthetic Derivative F-Curcumin Ameliorate the Expression of Cytokines in Autoimmune Encephalomyelitis Mouse Models of Multiple Sclerosis |
| Curcumin | Multiple Sclerosis | 14 | PM | 38112964 | 📋 | Neuroprotective effect of curcumin against experimental autoimmune encephalomyelitis-induced cognitive and physical impairments in mice: an insight into the role of the AMPK/SIRT1 pathway |
| Curcumin | Multiple Sclerosis | 13 | PM | 37660318 | 📋 | Curcumin's spice-infused therapeutic promise: disease severity alleviation in a mouse model of multiple sclerosis via modulation of immune responses |
| Curcumin | Multiple Sclerosis | 12 | PM | 35955792 | 📋 | Dual Mechanism of Action of Curcumin in Experimental Models of Multiple Sclerosis |
| Curcumin | Multiple Sclerosis | 11 | PM | 35908626 | 📋 | Curcumin Regulates Anti-Inflammatory Responses by AXL/JAK2/STAT3 Signaling Pathway in experimental autoimmune encephalomyelitis |
| Curcumin | Multiple Sclerosis | 10 | PM | 34331683 | 📋 | Targeting Nuclear Factor-Kappa B Signaling Pathway by Curcumin: Implications for the Treatment of Multiple Sclerosis |
| Curcumin | Multiple Sclerosis | 9 | PM | 33953873 | 📋 | Molecular effects of curcumin on the experimental autoimmune encephalomyelitis |
| Curcumin | Multiple Sclerosis | 5 | PM | 32229332 | 📋 | Targeted Immunomodulation of Inflammatory Monocytes Across the Blood-Brain Barrier by Curcumin-Loaded Nanoparticles Delays the Progression of Experimental Autoimmune Encephalomyelitis |
| Curcumin | Multiple Sclerosis | 6 | PM | 30536381 | 📋 | Curcumin as a Therapeutic Candidate for Multiple Sclerosis: Molecular Mechanisms and Targets |
| Curcumin | Multiple Sclerosis | 7 | PM | 29079885 | 📋 | Therapeutic Potential of Curcumin for Multiple Sclerosis |
| Curcumin | Multiple Sclerosis | 4 | PM | 26211978 | 📋 | Polymerized Nano-Curcumin Attenuates Neurological Symptoms in EAE Model of Multiple Sclerosis Through Down Regulation of Inflammatory and Oxidative Processes and Enhancing Neuroprotection and Myelin Repair |
| Curcumin | Multiple Sclerosis | 8 | PM | 24998635 | 📋 | Study of Curcumin Immunomodulatory Effects on Reactive Astrocyte Cell Function |
| Curcumin | Multiple Sclerosis | 1 | PM | 20828641 | 📋 | Curcumin Has Bright Prospects for the Treatment of Multiple Sclerosis |
| Curcumin | Multiple Sclerosis | 3 | PM | 19539560 | 📋 | Amelioration of Experimental Autoimmune Encephalomyelitis by Curcumin Treatment Through Inhibition of IL-17 Production |
| Curcumin | Multiple Sclerosis | 2 | PM | 12055272 | 📋 | Curcumin Inhibits Experimental Allergic Encephalomyelitis by Blocking IL-12 Signaling Through Janus kinase-STAT Pathway in T Lymphocytes |
| Curcumin | Neuroblastoma | 12 | PM | 38071672 | 📋 | Synergistic anti-proliferative and apoptotic effect of NVP-BEZ235 and curcumin on human SH-SY5Y neuroblastoma cells |
| Curcumin | Neuroblastoma | 11 | PM | 33105719 | 📋 | Curcumin's Beneficial Effects on Neuroblastoma: Mechanisms, Challenges, and Potential Solutions |
| Curcumin | Neuroblastoma | 10 | PM | 33075785 | 📋 | Antitumoral Effects of Curcumin (Curcuma longa L.) and Thymoquinone (Nigella sativa L.) on Neuroblastoma Cell Lines |
| Curcumin | Neuroblastoma | 9 | PM | 32623920 | 📋 | GSK-3β Inhibition by Curcumin Mitigates Amyloidogenesis via TFEB Activation and Anti-Oxidative Activity in Human Neuroblastoma Cells |
| Curcumin | Neuroblastoma | 1 | PM | 25179440 | 📋 | Curcumin Induces Apoptosis in Human Neuroblastoma Cells via Inhibition of AKT and Foxo3a Nuclear Translocation |
| Curcumin | Neuroblastoma | 6 | PM | 21236599 | 📋 | Curcumin Regulates Low-Linear Energy Transfer γ-Radiation-Induced NFκB-dependent Telomerase Activity in Human Neuroblastoma Cells |
| Curcumin | Neuroblastoma | 2 | PM | 20525240 | 📋 | Enhanced Anti-Tumor Activity of a New Curcumin-Related Compound Against Melanoma and Neuroblastoma Cells |
| Curcumin | Neuroblastoma | 5 | PM | 18383847 | 📋 | Curcumin Induces Apoptosis in Human Neuroblastoma Cells via Inhibition of NFkappaB |
| Curcumin | Neuroblastoma | 8 | PM | 18305409 | 📋 | Curcumin Inhibits NFkappaB Mediated Radioprotection and Modulate Apoptosis Related Genes in Human Neuroblastoma Cells |
| Curcumin | Neuroblastoma | 7 | PM | 17435663 | 📋 | In Vitro Assessment of Curcumin Against Murine Neuroblastoma Cells |
| Curcumin | Neuroblastoma | 3 | PM | 15161054 | 📋 | Curcumin and Resveratrol Induce Apoptosis and Nuclear Translocation and Activation of p53 in Human Neuroblastoma |
| Curcumin | Neuroblastoma | 4 | PM | 12692251 | 📋 | Inhibition of Protease-Resistant Prion Protein Accumulation in Vitro by Curcumin |
| Curcumin | Neurodegenerative Disease | 43 | PM | 37132107 | 📋 | The effects of curcumin on astrocytes in common neurodegenerative conditions |
| Curcumin | Neurodegenerative Disease | 42 | PM | 36947339 | 📋 | Low-dose curcumin enhances hippocampal neurogenesis and memory retention in young mice |
| Curcumin | Neurodegenerative Disease | 41 | PM | 36456663 | 📋 | Bioenhancing effects of piperine and curcumin on triterpenoid pharmacokinetics and neurodegenerative metabolomes from Centella asiatica extract in beagle dogs |
| Curcumin | Neurodegenerative Disease | 40 | PM | 35790042 | 📋 | Ameliorating potential of curcumin and its analogue in central nervous system disorders and related conditions: A review of molecular pathways |
| Curcumin | Neurodegenerative Disease | 39 | PM | 35327278 | 📋 | Curcumin Suppresses Lead-Induced Inflammation and Memory Loss in Mouse Model and In Silico Molecular Docking |
| Curcumin | Neurodegenerative Disease | 38 | PM | 35057429 | 📋 | Post-Ischemic Brain Neurodegeneration in the Form of Alzheimer's Disease Proteinopathy: Possible Therapeutic Role of Curcumin |
| Curcumin | Neurodegenerative Disease | 37 | PM | 35011468 | 📋 | New Promising Therapeutic Avenues of Curcumin in Brain Diseases |
| Curcumin | Neurodegenerative Disease | 36 | PM | 34867295 | 📋 | The Interplay of the Unfolded Protein Response in Neurodegenerative Diseases: A Therapeutic Role of Curcumin |
| Curcumin | Neurodegenerative Disease | 35 | PM | 34720999 | 📋 | Curcumin Reduced H 2 O 2- and G2385R-LRRK2-Induced Neurodegeneration |
| Curcumin | Neurodegenerative Disease | 34 | PM | 34496365 | 📋 | The Functional Roles of Curcumin on Astrocytes in Neurodegenerative Diseases |
| Curcumin | Neurodegenerative Disease | 33 | PM | 33893674 | 📋 | Curcumin: A small molecule with big functionality against amyloid aggregation in neurodegenerative diseases and type 2 diabetes |
| Curcumin | Neurodegenerative Disease | 32 | PM | 33575335 | 📋 | Neuroprotective Effect of Turmeric Extract in Combination with Its Essential Oil and Enhanced Brain Bioavailability in an Animal Model |
| Curcumin | Neurodegenerative Disease | 31 | PM | 33466849 | 📋 | Beneficial Effects of Epigallocatechin-3- O-Gallate, Chlorogenic Acid, Resveratrol, and Curcumin on Neurodegenerative Diseases |
| Curcumin | Neurodegenerative Disease | 30 | PM | 33176649 | 📋 | Curcumin Prevents Neuroinflammation by Inducing Microglia to Transform into the M2-phenotype via CaMKKβ-dependent Activation of the AMP-Activated Protein Kinase Signal Pathway |
| Curcumin | Neurodegenerative Disease | 29 | PM | 32942739 | 📋 | Curcumin Inhibits the Primary Nucleation of Amyloid-Beta Peptide: A Molecular Dynamics Study |
| Curcumin | Neurodegenerative Disease | 28 | PM | 32832482 | 📋 | Novel Insight to Neuroprotective Potential of Curcumin: A Mechanistic Review of Possible Involvement of Mitochondrial Biogenesis and PI3/Akt/ GSK3 or PI3/Akt/CREB/BDNF Signaling Pathways |
| Curcumin | Neurodegenerative Disease | 27 | PM | 32610099 | 📋 | Compounds That Extend Longevity Are Protective in Neurodegenerative Diseases and Provide a Novel Treatment Strategy for These Devastating Disorders |
| Curcumin | Neurodegenerative Disease | 8 | PM | 29287782 | 📋 | Naringenin-induced Enhanced Antioxidant Defence System Meliorates Cholinergic Neurotransmission and Consolidates Memory in Male Rats |
| Curcumin | Neurodegenerative Disease | 19 | PM | 27423629 | 📋 | Curcumin Alleviates Oxidative Stress and Mitochondrial Dysfunction in Astrocytes |
| Curcumin | Neurodegenerative Disease | 18 | PM | 26824354 | 📋 | Curcumin Ameliorates the Reduction Effect of PGE2 on Fibrillar β-Amyloid Peptide (1-42)-Induced Microglial Phagocytosis Through the Inhibition of EP2-PKA Signaling in N9 Microglial Cells |
| Curcumin | Neurodegenerative Disease | 22 | PM | 26608462 | 📋 | Curcumin Inhibits Apoptosis by Regulating Intracellular Calcium Release, Reactive Oxygen Species and Mitochondrial Depolarization Levels in SH-SY5Y Neuronal Cells |
| Curcumin | Neurodegenerative Disease | 26 | PM | 26457241 | 📋 | "Curcumin, the King of Spices": Epigenetic Regulatory Mechanisms in the Prevention of Cancer, Neurological, and Inflammatory Diseases |
| Curcumin | Neurodegenerative Disease | 7 | PM | 26254982 | 📋 | Curcumin Micelles Improve Mitochondrial Function in Neuronal PC12 Cells and Brains of NMRI Mice - Impact on Bioavailability |
| Curcumin | Neurodegenerative Disease | 16 | PM | 26216111 | 📋 | Neurogenesis and Neuroprotection in Postischemic Brain Neurodegeneration With Alzheimer Phenotype: Is There a Role for Curcumin? |
| Curcumin | Neurodegenerative Disease | 24 | PM | 26064904 | 📋 | Implication of Caspase-3 as a Common Therapeutic Target for Multineurodegenerative Disorders and Its Inhibition Using Nonpeptidyl Natural Compounds |
| Curcumin | Neurodegenerative Disease | 1 | PM | 26053510 | 📋 | Protection of Curcumin Against Amyloid-β-Induced Cell Damage and Death Involves the Prevention From NMDA Receptor-Mediated Intracellular Ca2+ Elevation |
| Curcumin | Neurodegenerative Disease | 9 | PM | 25199698 | 📋 | Mitigation of Acrylamide-Induced Behavioral Deficits, Oxidative Impairments and Neurotoxicity by Oral Supplements of Geraniol (A Monoterpene) in a Rat Model |
| Curcumin | Neurodegenerative Disease | 12 | PM | 25033705 | 📋 | Curcumin Increased the Differentiation Rate of Neurons in Neural Stem Cells via Wnt Signaling in Vitro Study |
| Curcumin | Neurodegenerative Disease | 25 | PM | 24788895 | 📋 | Epigenetic Impact of Curcumin on Stroke Prevention |
| Curcumin | Neurodegenerative Disease | 11 | PM | 23816368 | 📋 | The Curry Spice Curcumin Attenuates Beta-Amyloid-Induced Toxicity Through Beta-Catenin and PI3K Signaling in Rat Organotypic Hippocampal Slice Culture |
| Curcumin | Neurodegenerative Disease | 23 | PM | 22145830 | 📋 | Curcuminoids Promote Neurite Outgrowth in PC12 Cells Through MAPK/ERK- And PKC-dependent Pathways |
| Curcumin | Neurodegenerative Disease | 14 | PM | 20861489 | 📋 | Curcumin Protects Against NMDA-induced Toxicity: A Possible Role for NR2A Subunit |
| Curcumin | Neurodegenerative Disease | 4 | PM | 20553189 | 📋 | Curcumin Exerts Neuroprotective Effects Against Homocysteine Intracerebroventricular Injection-Induced Cognitive Impairment and Oxidative Stress in Rat Brain |
| Curcumin | Neurodegenerative Disease | 5 | PM | 19925811 | 📋 | Protective Effect of Curcumin Against Intracerebral Streptozotocin Induced Impairment in Memory and Cerebral Blood Flow |
| Curcumin | Neurodegenerative Disease | 15 | PM | 19879308 | 📋 | Curcumin Produces Neuroprotective Effects via Activating Brain-Derived Neurotrophic factor/TrkB-dependent MAPK and PI-3K Cascades in Rodent Cortical Neurons |
| Curcumin | Neurodegenerative Disease | 10 | PM | 18724833 | 📋 | Neuroprotective and Antiinflammatory Properties of a Novel Demethylated Curcuminoid |
| Curcumin | Neurodegenerative Disease | 13 | PM | 18583042 | 📋 | Exposure to Metal Ions Regulates mRNA Levels of APP and BACE1 in PC12 Cells: Blockage by Curcumin |
| Curcumin | Neurodegenerative Disease | 2 | PM | 18408903 | 📋 | Inhibition of Monoamine oxidase-B by the Polyphenolic Compound, Curcumin and Its Metabolite Tetrahydrocurcumin, in a Model of Parkinson's Disease Induced by MPTP Neurodegeneration in Mice |
| Curcumin | Neurodegenerative Disease | 20 | PM | 18368483 | 📋 | Curcumin Protects Dopaminergic Neuron Against LPS Induced Neurotoxicity in Primary Rat Neuron/Glia Culture |
| Curcumin | Neurodegenerative Disease | 3 | PM | 17300872 | 📋 | Curcumin Attenuates the Kainic Acid-Induced Hippocampal Cell Death in the Mice |
| Curcumin | Neurodegenerative Disease | 21 | PM | 17184173 | 📋 | Mitochondrial Complex I Inhibition in Parkinson's Disease: How Can Curcumin Protect Mitochondria? |
| Curcumin | Neurodegenerative Disease | 6 | PM | 16802111 | 📋 | Neuroprotective and Anti-Ageing Effects of Curcumin in Aged Rat Brain Regions |
| Curcumin | Neurodegenerative Disease | 17 | PM | 15073579 | 📋 | Curcumin Inhibits Dose-Dependently and Time-Dependently Neuroglial Cell Proliferation and Growth |
| Curcumin | Neurofibromatosis | 1 | PM | 28754004 | 📋 | Synergistic Interplay Between Curcumin and Polyphenol-Rich Foods in the Mediterranean Diet: Therapeutic Prospects for Neurofibromatosis 1 Patients |
| Curcumin | Neurofibromatosis | 2 | PM | 21903608 | 📋 | Combining Curcumin (Diferuloylmethane) and Heat Shock Protein Inhibition for Neurofibromatosis 2 Treatment: Analysis of Response and Resistance Pathways |
| Curcumin | Neuroinflammation | 27 | PM | 38428651 | 📋 | Curcumin abrogates cobalt-induced neuroinflammation by suppressing proinflammatory cytokines release, inhibiting microgliosis and modulation of ERK/MAPK signaling pathway |
| Curcumin | Neuroinflammation | 26 | PM | 38228998 | 📋 | Administration with curcumin alleviates spinal cord ischemia-reperfusion injury by regulating anti-oxidative stress and microglia activation-mediated neuroinflammation via Nrf2/NF-κB axis |
| Curcumin | Neuroinflammation | 25 | PM | 37664456 | 📋 | Curcumin, inflammation, and neurological disorders: How are they linked? |
| Curcumin | Neuroinflammation | 24 | PM | 37626603 | 📋 | Curcumae radix Reduces Endoplasmic Reticulum Stress in Mice with Chronic Neuroinflammation |
| Curcumin | Neuroinflammation | 23 | PM | 37562565 | 📋 | Curcumin modulates astrocyte function under basal and inflammatory conditions |
| Curcumin | Neuroinflammation | 22 | PM | 35781221 | 📋 | Curcumin-Attenuated TREM-1/DAP12/NLRP3/Caspase-1/IL1B, TLR4/NF-κB Pathways, and Tau Hyperphosphorylation Induced by 1,2-Diacetyl Benzene: An in Vitro and in Silico Study |
| Curcumin | Neuroinflammation | 21 | PM | 35381181 | 📋 | Curcumin attenuates intracerebral hemorrhage-induced neuronal apoptosis and neuroinflammation by suppressing the JAK1/STAT1 pathway |
| Curcumin | Neuroinflammation | 20 | PM | 35294663 | 📋 | Pharmacological considerations for treating neuroinflammation with curcumin in Alzheimer's disease |
| Curcumin | Neuroinflammation | 19 | PM | 35056657 | 📋 | Inflammaging and Brain: Curcumin and Its Beneficial Potential as Regulator of Microglia Activation |
| Curcumin | Neuroinflammation | 18 | PM | 34988899 | 📋 | The Effects of Modified Curcumin Preparations on Glial Morphology in Aging and Neuroinflammation |
| Curcumin | Neuroinflammation | 17 | PM | 34636389 | 📋 | Prophylactic treatment of curcumin in a rat model of depression by attenuating hippocampal synaptic loss |
| Curcumin | Neuroinflammation | 16 | PM | 34577062 | 📋 | Curcumin and Nano-Curcumin Mitigate Copper Neurotoxicity by Modulating Oxidative Stress, Inflammation, and Akt/GSK-3β Signaling |
| Curcumin | Neuroinflammation | 15 | PM | 33849031 | 📋 | Curcumin Reduces Neuroinflammation and Improves the Impairments of Anesthetics on Learning and Memory by Regulating the Expression of miR-181a-5p |
| Curcumin | Neuroinflammation | 14 | PM | 33748578 | 📋 | Curcumin Reduces Cognitive Deficits by Inhibiting Neuroinflammation through the Endoplasmic Reticulum Stress Pathway in Apolipoprotein E4 Transgenic Mice |
| Curcumin | Neuroinflammation | 13 | PM | 33489032 | 📋 | Curcumin inhibits APOE4-induced injury by activating peroxisome proliferator-activated receptor-γ (PPARγ) in SH-SY5Y cells |
| Curcumin | Neuroinflammation | 11 | PM | 33176649 | 📋 | Curcumin Prevents Neuroinflammation by Inducing Microglia to Transform into the M2-phenotype via CaMKKβ-dependent Activation of the AMP-Activated Protein Kinase Signal Pathway |
| Curcumin | Neuroinflammation | 10 | PM | 33098686 | 📋 | Neuromodulatory effect of curcumin on catecholamine systems and inflammatory cytokines in ovariectomized female rats |
| Curcumin | Neuroinflammation | 9 | PM | 32585605 | 📋 | Protective Effects of Maternal Administration of Curcumin and Hesperidin in the Rat Offspring Following Repeated Febrile Seizure: Role of Inflammation and TLR4 |
| Curcumin | Neuroinflammation | 7 | PM | 30666189 | 📋 | Neuroprotective Effects of Curcumin on IL-1β-Induced Neuronal Apoptosis and Depression-Like Behaviors Caused by Chronic Stress in Rats |
| Curcumin | Neuroinflammation | 6 | PM | 30488803 | 📋 | Molecular Mechanisms of Curcumin in Neuroinflammatory Disorders: A Mini Review of Current Evidences |
| Curcumin | Neuroinflammation | 5 | PM | 29115589 | 📋 | Anti-neuroinflammatory Effect of Curcumin on Pam3CSK4-stimulated Microglial Cells |
| Curcumin | Neuroinflammation | 8 | PM | 29079885 | 📋 | Therapeutic Potential of Curcumin for Multiple Sclerosis |
| Curcumin | Neuroinflammation | 1 | PM | 28222524 | 📋 | A Combination of Resveratrol and Curcumin Is Effective Against Aluminum Chloride-Induced Neuroinflammation in Rats |
| Curcumin | Neuroinflammation | 12 | PM | 26970969 | 📋 | Piperine Augments the Protective Effect of Curcumin Against Lipopolysaccharide-Induced Neurobehavioral and Neurochemical Deficits in Mice |
| Curcumin | Neuroinflammation | 3 | PM | 26387034 | 📋 | CISD2 Serves a Novel Role as a Suppressor of Nitric Oxide Signalling and Curcumin Increases CISD2 Expression in Spinal Cord Injuries |
| Curcumin | Neuroinflammation | 4 | PM | 25988362 | 📋 | Intrathecal Curcumin Attenuates Pain Hypersensitivity and Decreases Spinal Neuroinflammation in Rat Model of Monoarthritis |
| Curcumin | Neuroinflammation | 2 | PM | 22156608 | 📋 | Curcumins Promote Monocytic Gene Expression Related to β-Amyloid and Superoxide Dismutase Clearance |
| Curcumin | Neurological Disorders | 5 | PM | 37664456 | 📋 | Curcumin, inflammation, and neurological disorders: How are they linked? |
| Curcumin | Neurological Disorders | 4 | PM | 35482938 | 📋 | Therapeutic role of curcumin in adult neurogenesis for management of psychiatric and neurological disorders: a scientometric study to an in-depth review |
| Curcumin | Neurological Disorders | 3 | PM | 34528307 | 📋 | The clinical use of curcumin on neurological disorders: An updated systematic review of clinical trials |
| Curcumin | Neurological Disorders | 2 | PM | 33946356 | 📋 | Curcuma Longa, the "Golden Spice" to Counteract Neuroinflammaging and Cognitive Decline-What Have We Learned and What Needs to Be Done |
| Curcumin | Neurological Disorders | 1 | PM | 33211286 | 📋 | Curcumin Attenuates Hypoxia-Induced Oxidative Neurotoxicity, Apoptosis, Calcium, and Zinc Ion Influxes in a Neuronal Cell Line: Involvement of TRPM2 Channel |
| Curcumin | Neuronal Damage | 5 | PM | 34589382 | 📋 | Curcumin Alleviates Oxygen-Glucose-Deprivation/Reperfusion-Induced Oxidative Damage by Regulating miR-1287-5p/LONP2 Axis in SH-SY5Y Cells |
| Curcumin | Neuronal Damage | 3 | PM | 33538682 | 📋 | Curcumin Efficacy in a Serum/glucose Deprivation-induced Neuronal PC12 Injury Model |
| Curcumin | Neuronal Damage | 2 | PM | 32650839 | 📋 | Curcumin Prevents Neuronal Loss and Structural Changes in the Superior Cervical (Sympathetic) Ganglion Induced by Chronic Sleep Deprivation, in the Rat Model |
| Curcumin | Neuronal Damage | 1 | PM | 18583042 | 📋 | Exposure to Metal Ions Regulates mRNA Levels of APP and BACE1 in PC12 Cells: Blockage by Curcumin |
| Curcumin | Neuropathic Pain | 9 | PM | 37892476 | 📋 | Turmeric Bioactive Compounds Alleviate Spinal Nerve Ligation-Induced Neuropathic Pain by Suppressing Glial Activation and Improving Mitochondrial Function in Spinal Cord and Amygdala |
| Curcumin | Neuropathic Pain | 8 | PM | 36931068 | 📋 | Curcumin promotes microglial M2 polarization and suppresses chronic constriction: Injury-induced neuropathic pain in a rat model of peripheral neuropathy |
| Curcumin | Neuropathic Pain | 4 | PM | 36567422 | 📋 | Involvement of TRPM7 Channel on the Induction of Diabetic Neuropathic Pain in Mice: Protective Role of Selenium and Curcumin |
| Curcumin | Neuropathic Pain | 2 | PM | 35763932 | 📋 | Computational approach to decode the mechanism of curcuminoids against neuropathic pain |
| Curcumin | Neuropathic Pain | 7 | PM | 33925121 | 📋 | Effects of Curcumin and Its Different Formulations in Preclinical and Clinical Studies of Peripheral Neuropathic and Postoperative Pain: A Comprehensive Review |
| Curcumin | Neuropathic Pain | 6 | PM | 33907454 | 📋 | Curcumin Alleviates Chronic Pain and Improves Cognitive Impairment via Enhancing Hippocampal Neurogenesis in Sciatic Nerve Constriction Rats |
| Curcumin | Neuropathic Pain | 5 | PM | 27381056 | 📋 | Curcumin Ameliorates Neuropathic Pain by Down-Regulating Spinal IL-1β via Suppressing Astroglial NALP1 Inflammasome and JAK2-STAT3 Signalling |
| Curcumin | Neuropathic Pain | 1 | PM | 24297305 | 📋 | Chronic Curcumin Treatment Normalizes Depression-Like Behaviors in Mice With Mononeuropathy: Involvement of Supraspinal Serotonergic System and GABAA Receptor |
| Curcumin | Neuropathic Pain | 3 | PM | 21945716 | 📋 | Curcumin Exerts Antinociceptive Effects in a Mouse Model of Neuropathic Pain: Descending Monoamine System and Opioid Receptors Are Differentially Involved |
| Curcumin | Neurotoxicity | 15 | PM | 38480956 | 📋 | Curcumin relieves oxaliplatin-induced neuropathic pain via reducing inflammation and activating antioxidant response |
| Curcumin | Neurotoxicity | 14 | PM | 38417317 | 📋 | Mechanism of KAT2A regulation of H3K36ac in manganese-induced oxidative damage to mitochondria in the nervous system and intervention by curcumin |
| Curcumin | Neurotoxicity | 12 | PM | 37716069 | 📋 | Curcumin protects against fenvalerate-induced neurotoxicity in zebrafish (Danio rerio) larvae through inhibition of oxidative stress |
| Curcumin | Neurotoxicity | 11 | PM | 37423901 | 📋 | Neurodevelopmental toxicity of bisphenol AF in zebrafish larvae and the protective effects of curcumin |
| Curcumin | Neurotoxicity | 10 | PM | 36949340 | 📋 | Curcumin protects against doxorubicin induced oxidative stress by regulating the Keap1-Nrf2-ARE and autophagy signaling pathways |
| Curcumin | Neurotoxicity | 9 | PM | 35701115 | 📋 | [Curcumin alleviates the manganese-induced neurotoxicity by promoting autophagy in rat models of manganism] |
| Curcumin | Neurotoxicity | 8 | PM | 35367881 | 📋 | Curcumin protects against manganese-induced neurotoxicity in rat by regulating oxidative stress-related gene expression via H3K27 acetylation |
| Curcumin | Neurotoxicity | 3 | PM | 34942627 | 📋 | L-Ascorbic Acid and Curcumin prevents Brain Damage-induced via Lead Acetate in Rats: Possible Mechanisms |
| Curcumin | Neurotoxicity | 7 | PM | 33819551 | 📋 | Curcumin attenuates spatial memory impairment by anti-oxidative, anti-apoptosis, and anti-inflammatory mechanism against methamphetamine neurotoxicity in male Wistar rats: histological and biochemical changes |
| Curcumin | Neurotoxicity | 13 | PM | 25791922 | 📋 | Curcumin attenuates glutamate neurotoxicity in the hippocampus by suppression of ER stress-associated TXNIP/NLRP3 inflammasome activation in a manner dependent on AMPK |
| Curcumin | Neurotoxicity | 4 | PM | 21656326 | 📋 | Curcumin Attenuates Aluminum-Induced Oxidative Stress and Mitochondrial Dysfunction in Rat Brain |
| Curcumin | Neurotoxicity | 1 | PM | 20869986 | 📋 | Curcumin Attenuates Peroxynitrite-Induced Neurotoxicity in Spiral Ganglion Neurons |
| Curcumin | Neurotoxicity | 5 | PM | 20054649 | 📋 | Modulation of Carbohydrate Metabolism During N-methyl N-nitrosourea Induced Neurotoxicity in Mice: Role of Curcumin |
| Curcumin | Neurotoxicity | 2 | PM | 17300872 | 📋 | Curcumin Attenuates the Kainic Acid-Induced Hippocampal Cell Death in the Mice |
| Curcumin | Neurotoxicity | 6 | PM | 10548748 | 📋 | Neuroprotective Role of Curcumin From Curcuma Longa on Ethanol-Induced Brain Damage |
| Curcumin | Optic Neuropathy | 1 | PM | 33581265 | 📋 | How Curcumin Affects Hyperglycemia-Induced Optic Nerve Damage: A Short Review |
| Curcumin | Orofacial Pain | 4 | PM | 37632838 | 📋 | Curcumin alleviates orofacial allodynia and improves cognitive impairment via regulating hippocampal synaptic plasticity in a mouse model of trigeminal neuralgia |
| Curcumin | Orofacial Pain | 3 | PM | 36096139 | 📋 | The Efficacy of Curcumin Patch as an Adjuvant Therapeutic Agent in Managing Acute Orofacial Pain on the Post-Cleft Lip and Cleft Palate Surgery Patients: A Pragmatic Trial |
| Curcumin | Orofacial Pain | 2 | PM | 35682028 | 📋 | Effectiveness of Curcumin in Reducing Self-Rated Pain-Levels in the Orofacial Region: A Systematic Review of Randomized-Controlled Trials |
| Curcumin | Orofacial Pain | 1 | PM | 19051211 | 📋 | Evaluation of Antihyperalgesic Effect of Curcumin on Formalin-Induced Orofacial Pain in Rat |
| Curcumin | Pain | 16 | PM | 36274168 | 📋 | Combination of curcumin and piperine synergistically improves pain-like behaviors in mouse models of pain with no potential CNS side effects |
| Curcumin | Pain | 15 | PM | 35690654 | 📋 | Curcumin and metformin synergistically modulate peripheral and central immune mechanisms of pain |
| Curcumin | Pain | 3 | PM | 35032552 | 📋 | Curcumin induces peripheral antinociception by opioidergic and cannabinoidergic mechanism: Pharmacological evidence |
| Curcumin | Pain | 14 | PM | 34539332 | 📋 | Curcumin Exerts Antinociceptive Effects in Cancer-Induced Bone Pain via an Endogenous Opioid Mechanism |
| Curcumin | Pain | 13 | PM | 34312922 | 📋 | A review of therapeutic potentials of turmeric (Curcuma longa) and its active constituent, curcumin, on inflammatory disorders, pain, and their related patents |
| Curcumin | Pain | 12 | PM | 33925121 | 📋 | Effects of Curcumin and Its Different Formulations in Preclinical and Clinical Studies of Peripheral Neuropathic and Postoperative Pain: A Comprehensive Review |
| Curcumin | Pain | 10 | PM | 32981501 | 📋 | Curcumin and its Multi-target Function Against Pain and Inflammation: An Update of Pre-clinical Data |
| Curcumin | Pain | 9 | PM | 32664057 | 📋 | Efficacy of high-dissolution turmeric-sesame formulation for pain relief in adult subjects with acute musculoskeletal pain compared to acetaminophen: A randomized controlled study |
| Curcumin | Pain | 5 | PM | 32387235 | 📋 | Anti-inflammatory and Antinociceptive Effects of Curcuma Kwangsiensis and Its Bioactive Terpenoids in Vivo and in Vitro |
| Curcumin | Pain | 7 | PM | 30466988 | 📋 | Curcumin Downregulates Expression of Opioid-Related Nociceptin Receptor Gene (OPRL1) in Isolated Neuroglia Cells |
| Curcumin | Pain | 8 | PM | 30195871 | 📋 | Role of Curcumin in the Management of Pathological Pain |
| Curcumin | Pain | 1 | PM | 25352926 | 📋 | A New Curcuma Extract (Flexofytol®) in Osteoarthritis: Results From a Belgian Real-Life Experience |
| Curcumin | Pain | 2 | PM | 23091682 | 📋 | Evidence for the Participation of ATP-sensitive Potassium Channels in the Antinociceptive Effect of Curcumin |
| Curcumin | Pain | 6 | PM | 19070135 | 📋 | Interaction Between Curcumin and Opioid System in the Formalin Test of Rats |
| Curcumin | Pain | 4 | PM | 18817212 | 📋 | The Effect of Curcumin (Active Substance of Turmeric) on the Acetic Acid-Induced Visceral Nociception in Rats |
| Curcumin | Parkinson's Disease | 41 | PM | 37484231 | 📋 | The dosage of curcumin to alleviate movement symptoms in a 6-hydroxydopamine-induced Parkinson's disease rat model |
| Curcumin | Parkinson's Disease | 40 | PM | 37388445 | 📋 | Curcumin alleviates 1-methyl- 4-phenyl- 1,2,3,6-tetrahydropyridine- induced Parkinson's disease in mice via modulating gut microbiota and short-chain fatty acids |
| Curcumin | Parkinson's Disease | 39 | PM | 37247135 | 📋 | Membrane-stabilizing and protective effects of curcumin in a rotenone-induced rat model of Parkinson disease |
| Curcumin | Parkinson's Disease | 38 | PM | 37234646 | 📋 | Curcumin protects against rotenone-induced Parkinson's disease in mice by inhibiting microglial NLRP3 inflammasome activation and alleviating mitochondrial dysfunction |
| Curcumin | Parkinson's Disease | 37 | PM | 36989171 | 📋 | Curcumin Modulates p62-Keap1-Nrf2-Mediated Autophagy in Rotenone-Induced Parkinson's Disease Mouse Models |
| Curcumin | Parkinson's Disease | 36 | PM | 36742141 | 📋 | Curcumin modulation of L-dopa and rasagiline-induced neuroprotection in rotenone model of Parkinson's disease |
| Curcumin | Parkinson's Disease | 35 | PM | 36678536 | 📋 | Exploring the Neuroprotective Mechanism of Curcumin Inhibition of Intestinal Inflammation against Parkinson's Disease Based on the Gut-Brain Axis |
| Curcumin | Parkinson's Disease | 34 | PM | 36467550 | 📋 | Curcumin Regulates Gut Microbiota and Exerts a Neuroprotective Effect in the MPTP Model of Parkinson's Disease |
| Curcumin | Parkinson's Disease | 33 | PM | 36165412 | 📋 | 6-Hydroxydopamine-Induced Neurotoxicity in Rat Model of Parkinson's Disease: Is Reversed via Anti-Oxidative Activities of Curcumin and Aerobic Exercise Therapy |
| Curcumin | Parkinson's Disease | 32 | PM | 36034698 | 📋 | Curcumin-driven reprogramming of the gut microbiota and metabolome ameliorates motor deficits and neuroinflammation in a mouse model of Parkinson's disease |
| Curcumin | Parkinson's Disease | 31 | PM | 35719816 | 📋 | An Overview of Parkinson's Disease: Curcumin as a Possible Alternative Treatment |
| Curcumin | Parkinson's Disease | 30 | PM | 35556131 | 📋 | The Effect of Curcumin on Idiopathic Parkinson Disease: A Clinical and Skin Biopsy Study |
| Curcumin | Parkinson's Disease | 29 | PM | 35526734 | 📋 | Curcumin can improve Parkinson's disease via activating BDNF/PI3k/Akt signaling pathways |
| Curcumin | Parkinson's Disease | 28 | PM | 35239141 | 📋 | Protective effect of curcumin against rotenone-induced substantia nigra pars compacta neuronal dysfunction |
| Curcumin | Parkinson's Disease | 27 | PM | 35122926 | 📋 | Neuroprotective effects of curcumin via autophagy induction in 6-hydroxydopamine Parkinson's models |
| Curcumin | Parkinson's Disease | 26 | PM | 35068069 | 📋 | Neuroprotective effects of curcumin on the cerebellum in a rotenone-induced Parkinson's Disease Model |
| Curcumin | Parkinson's Disease | 25 | PM | 34817361 | 📋 | Curcumin for parkinson´s disease: potential therapeutic effects, molecular mechanisms, and nanoformulations to enhance its efficacy |
| Curcumin | Parkinson's Disease | 24 | PM | 34681908 | 📋 | Neuroprotective Activities of Curcumin in Parkinson's Disease: A Review of the Literature |
| Curcumin | Parkinson's Disease | 23 | PM | 34189277 | 📋 | Curcumin pre-treatment may protect against mitochondrial damage in LRRK2-mutant Parkinson's disease and healthy control fibroblasts |
| Curcumin | Parkinson's Disease | 22 | PM | 34043864 | 📋 | Movement of Prion-Like α-Synuclein along the Gut-Brain Axis in Parkinson's Disease: A Potential Target of Curcumin Treatment |
| Curcumin | Parkinson's Disease | 11 | PM | 34042043 | 📋 | Parkinsonism-like disease induced by rotenone in rats: Treatment role of curcumin, dopamine agonist and adenosine A2A receptor antagonist |
| Curcumin | Parkinson's Disease | 21 | PM | 33023066 | 📋 | Neuroprotective Effect of Curcumin on the Nigrostriatal Pathway in a 6-Hydroxydopmine-Induced Rat Model of Parkinson's Disease is Mediated by α7-Nicotinic Receptors |
| Curcumin | Parkinson's Disease | 19 | PM | 28818104 | 📋 | Neuroprotective Properties of Curcumin in Toxin-Base Animal Models of Parkinson's Disease: A Systematic Experiment Literatures Review |
| Curcumin | Parkinson's Disease | 1 | PM | 27853890 | 📋 | Neuroprotective Potential of Curcumin in Combination With Piperine Against 6-hydroxy Dopamine Induced Motor Deficit and Neurochemical Alterations in Rats |
| Curcumin | Parkinson's Disease | 9 | PM | 26648392 | 📋 | Curcumin Ameliorates Dopaminergic Neuronal Oxidative Damage via Activation of the Akt/Nrf2 Pathway |
| Curcumin | Parkinson's Disease | 6 | PM | 26538809 | 📋 | Dietary Curcumin Supplementation Attenuates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) Neurotoxicity in C57BL Mice |
| Curcumin | Parkinson's Disease | 20 | PM | 26328004 | 📋 | Plant-derived Neuroprotective Agents in Parkinson's Disease |
| Curcumin | Parkinson's Disease | 8 | PM | 26035833 | 📋 | Curcumin Treatment Improves Motor Behavior in α-Synuclein Transgenic Mice |
| Curcumin | Parkinson's Disease | 5 | PM | 23210631 | 📋 | Curcumin Inhibition of JNKs Prevents Dopaminergic Neuronal Loss in a Mouse Model of Parkinson's Disease Through Suppressing Mitochondria Dysfunction |
| Curcumin | Parkinson's Disease | 10 | PM | 22211691 | 📋 | Curcumin: A Potential Neuroprotective Agent in Parkinson's Disease |
| Curcumin | Parkinson's Disease | 15 | PM | 21237271 | 📋 | Curcumin Protects Against A53T Alpha-Synuclein-Induced Toxicity in a PC12 Inducible Cell Model for Parkinsonism |
| Curcumin | Parkinson's Disease | 16 | PM | 21167259 | 📋 | Curcumin I Protects the Dopaminergic Cell Line SH-SY5Y From 6-hydroxydopamine-induced Neurotoxicity Through Attenuation of p53-mediated Apoptosis |
| Curcumin | Parkinson's Disease | 4 | PM | 20951685 | 📋 | Neuroprotective Effects of Curcumin on 6-hydroxydopamine-induced Parkinsonism in Rats: Behavioral, Neurochemical and Immunohistochemical Studies |
| Curcumin | Parkinson's Disease | 18 | PM | 20433710 | 📋 | Curcumin Reduces Alpha-Synuclein Induced Cytotoxicity in Parkinson's Disease Cell Model |
| Curcumin | Parkinson's Disease | 12 | PM | 20230279 | 📋 | Curcumin Prevents Dopaminergic Neuronal Death Through Inhibition of the c-Jun N-terminal Kinase Pathway |
| Curcumin | Parkinson's Disease | 13 | PM | 19464433 | 📋 | Curcumin Attenuates 6-hydroxydopamine-induced Cytotoxicity by Anti-Oxidation and Nuclear Factor-Kappa B Modulation in MES23.5 Cells |
| Curcumin | Parkinson's Disease | 2 | PM | 18408903 | 📋 | Inhibition of Monoamine oxidase-B by the Polyphenolic Compound, Curcumin and Its Metabolite Tetrahydrocurcumin, in a Model of Parkinson's Disease Induced by MPTP Neurodegeneration in Mice |
| Curcumin | Parkinson's Disease | 7 | PM | 18166164 | 📋 | Curcumin Treatment Alleviates the Effects of Glutathione Depletion in Vitro and in Vivo: Therapeutic Implications for Parkinson's Disease Explained via in Silico Studies |
| Curcumin | Parkinson's Disease | 17 | PM | 17184173 | 📋 | Mitochondrial Complex I Inhibition in Parkinson's Disease: How Can Curcumin Protect Mitochondria? |
| Curcumin | Parkinson's Disease | 14 | PM | 16547587 | 📋 | Curcumin Protects PC12 Cells Against 1-methyl-4-phenylpyridinium Ion-Induced Apoptosis by bcl-2-mitochondria-ROS-iNOS Pathway |
| Curcumin | Parkinson's Disease | 3 | PM | 16298737 | 📋 | Neuroprotective Properties of the Natural Phenolic Antioxidants Curcumin and Naringenin but Not Quercetin and Fisetin in a 6-OHDA Model of Parkinson's Disease |
| Curcumin | Peripheral Nerve Injury | 3 | PM | 36965643 | 📋 | The effects of curcumin and blueberry on axonal regeneration after peripheral nerve injury |
| Curcumin | Peripheral Nerve Injury | 2 | PM | 27651779 | 📋 | Curcumin Upregulates S100 Expression and Improves Regeneration of the Sciatic Nerve Following Its Complete Amputation in Mice |
| Curcumin | Peripheral Nerve Injury | 1 | PM | 26552010 | 📋 | Curcumin Promotes Nerve Regeneration and Functional Recovery After Sciatic Nerve Crush Injury in Diabetic Rats |
| Curcumin | Peripheral Neuropathy | 10 | PM | 33925121 | 📋 | Effects of Curcumin and Its Different Formulations in Preclinical and Clinical Studies of Peripheral Neuropathic and Postoperative Pain: A Comprehensive Review |
| Curcumin | Peripheral Neuropathy | 6 | PM | 33023197 | 📋 | Key Developments in the Potential of Curcumin for the Treatment of Peripheral Neuropathies |
| Curcumin | Peripheral Neuropathy | 7 | PM | 27215022 | 📋 | Effects of Curcumin on Sodium Currents of Dorsal Root Ganglion Neurons in Type 2 Diabetic Neuropathic Pain Rats |
| Curcumin | Peripheral Neuropathy | 8 | PM | 26282904 | 📋 | Effects of Curcumin on TTX-R Sodium Currents of Dorsal Root Ganglion Neurons in Type 2 Diabetic Rats With Diabetic Neuropathic Pain |
| Curcumin | Peripheral Neuropathy | 2 | PM | 26113793 | 📋 | Curcumin Ameliorates Functional and Structural Abnormalities in Cisplatin-induced Neuropathy |
| Curcumin | Peripheral Neuropathy | 9 | PM | 24315931 | 📋 | Effect of Curcumin on Diabetic Peripheral Neuropathic Pain: Possible Involvement of Opioid System |
| Curcumin | Peripheral Neuropathy | 1 | PM | 23250879 | 📋 | Curcumin Derivatives Promote Schwann Cell Differentiation and Improve Neuropathy in R98C CMT1B Mice |
| Curcumin | Peripheral Neuropathy | 3 | PM | 22281447 | 📋 | Therapeutic Role of Curcumin in Prevention of Biochemical and Behavioral Aberration Induced by Alcoholic Neuropathy in Laboratory Animals |
| Curcumin | Peripheral Neuropathy | 5 | PM | 17701891 | 📋 | Oral Curcumin Mitigates the Clinical and Neuropathologic Phenotype of the Trembler-J Mouse: A Potential Therapy for Inherited Neuropathy |
| Curcumin | Peripheral Neuropathy | 4 | PM | 16252242 | 📋 | Curcumin Treatment Abrogates Endoplasmic Reticulum Retention and Aggregation-Induced Apoptosis Associated With Neuropathy-Causing Myelin Protein Zero-Truncating Mutants |
| Curcumin | Pituitary Tumor | 5 | PM | 38764151 | 📋 | Curcumin affects autophagy of prolactinoma cells by upregulating miR-206 to exert antitumor effects |
| Curcumin | Pituitary Tumor | 4 | PM | 20405005 | 📋 | Growth Suppression of Mouse Pituitary Corticotroph Tumor AtT20 Cells by Curcumin: A Model for Treating Cushing's Disease |
| Curcumin | Pituitary Tumor | 2 | PM | 20160430 | 📋 | Curcumin Inhibits the Growth, Induces Apoptosis and Modulates the Function of Pituitary Folliculostellate Cells |
| Curcumin | Pituitary Tumor | 1 | PM | 19726538 | 📋 | Curcumin Acts as Anti-Tumorigenic and Hormone-Suppressive Agent in Murine and Human Pituitary Tumour Cells in Vitro and in Vivo |
| Curcumin | Pituitary Tumor | 3 | PM | 18450960 | 📋 | Curcumin (Diferuloylmethane) Inhibits Cell Proliferation, Induces Apoptosis, and Decreases Hormone Levels and Secretion in Pituitary Tumor Cells |
| Curcumin | Prion Diseases | 1 | PM | 18198391 | 📋 | Evaluation of Drugs for Treatment of Prion Infections of the Central Nervous System |
| Curcumin | Prion Diseases | 3 | PM | 17996023 | 📋 | Curcumin Binds to the Alpha-Helical Intermediate and to the Amyloid Form of Prion Protein - A New Mechanism for the Inhibition of PrP(Sc) Accumulation |
| Curcumin | Prion Diseases | 2 | PM | 12692251 | 📋 | Inhibition of Protease-Resistant Prion Protein Accumulation in Vitro by Curcumin |
| Curcumin | Pruritus | 1 | PM | 36997814 | 📋 | Curcumin inhibits the pruritus in mice through mast cell MrgprB2 receptor |
| Curcumin | Psychiatric Disorders | 3 | PM | 38672750 | 📋 | Curcumin as a Multifunctional Spice Ingredient against Mental Disorders in Humans: Current Clinical Studies and Bioavailability Concerns |
| Curcumin | Psychiatric Disorders | 2 | PM | 35482938 | 📋 | Therapeutic role of curcumin in adult neurogenesis for management of psychiatric and neurological disorders: a scientometric study to an in-depth review |
| Curcumin | Psychiatric Disorders | 1 | PM | 35204235 | 📋 | An Update on the Exploratory Use of Curcumin in Neuropsychiatric Disorders |
| Curcumin | Rheumatoid Arthritis | 22 | PM | 38699839 | 📋 | The efficacy of curcumin supplementation on serum total antioxidant capacity, malondialdehyde, and disease activity in women with rheumatoid arthritis: A randomized, double-blind, placebo-controlled clinical trial |
| Curcumin | Rheumatoid Arthritis | 21 | PM | 38625384 | 📋 | Patient-reported outcomes of curcumin supplementation in rheumatoid arthritis and psoriatic arthritis: a cross-sectional survey |
| Curcumin | Rheumatoid Arthritis | 20 | PM | 38487171 | 📋 | Immunomodulatory effects of curcumin on macrophage polarization in rheumatoid arthritis |
| Curcumin | Rheumatoid Arthritis | 19 | PM | 37325651 | 📋 | Effect of curcumin on rheumatoid arthritis: a systematic review and meta-analysis |
| Curcumin | Rheumatoid Arthritis | 18 | PM | 37031388 | 📋 | The Combined Effect of Curcumin and Crocin on the Reduction of Inflammatory Responses in Arthritic Rats |
| Curcumin | Rheumatoid Arthritis | 17 | PM | 36474395 | 📋 | Therapeutic Potential of Curcumin with and without Strengthening Exercises in Improving Rheumatoid Arthritis |
| Curcumin | Rheumatoid Arthritis | 16 | PM | 35609329 | 📋 | Curcumin alleviates rheumatoid arthritis progression through the phosphatidylinositol 3-kinase/protein kinase B pathway: an in vitro and in vivo study |
| Curcumin | Rheumatoid Arthritis | 15 | PM | 35473503 | 📋 | Curcumin relieved the rheumatoid arthritis progression via modulating the linc00052/miR-126-5p/PIAS2 axis |
| Curcumin | Rheumatoid Arthritis | 14 | PM | 35450396 | 📋 | The Impact of Curcumin on the Inflammatory Profile of SW982 Cells in a Rheumatoid Arthritis Model |
| Curcumin | Rheumatoid Arthritis | 13 | PM | 35178811 | 📋 | Effects of curcumin supplementation on metabolic parameters, inflammatory factors and obesity values in women with rheumatoid arthritis: A randomized, double-blind, placebo-controlled clinical trial |
| Curcumin | Rheumatoid Arthritis | 12 | PM | 34478838 | 📋 | Effects of curcumin supplementation on inflammatory biomarkers in patients with Rheumatoid Arthritis and Ulcerative colitis: A systematic review and meta-analysis |
| Curcumin | Rheumatoid Arthritis | 11 | PM | 34331695 | 📋 | The Clinical Use of Curcumin for the Treatment of Rheumatoid Arthritis: A Systematic Review of Clinical Trials |
| Curcumin | Rheumatoid Arthritis | 10 | PM | 33914984 | 📋 | Curcumin and rheumatoid arthritis: A systematic review of literature |
| Curcumin | Rheumatoid Arthritis | 9 | PM | 33404796 | 📋 | Immunomodulatory Effects of Curcumin in Rheumatoid Arthritis: Evidence from Molecular Mechanisms to Clinical Outcomes |
| Curcumin | Rheumatoid Arthritis | 8 | PM | 33377585 | 📋 | Curcumin ameliorates IL-1β-induced apoptosis by activating autophagy and inhibiting the NF-κB signaling pathway in rat primary articular chondrocytes |
| Curcumin | Rheumatoid Arthritis | 3 | PM | 25424293 | 📋 | Oral Administration of Curcumin (Curcuma Longa) Can Attenuate the Neutrophil Inflammatory Response in Zymosan-Induced Arthritis in Rats |
| Curcumin | Rheumatoid Arthritis | 7 | PM | 21345249 | 📋 | Molecular Targets of Natural Health Products in Arthritis |
| Curcumin | Rheumatoid Arthritis | 6 | PM | 20594343 | 📋 | Curcumin Mediated Suppression of Nuclear factor-κB Promotes Chondrogenic Differentiation of Mesenchymal Stem Cells in a High-Density Co-Culture Microenvironment |
| Curcumin | Rheumatoid Arthritis | 1 | PM | 19763044 | 📋 | Oral Administration of Curcumin Suppresses Production of Matrix Metalloproteinase (MMP)-1 and MMP-3 to Ameliorate Collagen-Induced Arthritis: Inhibition of the PKCdelta/JNK/c-Jun Pathway |
| Curcumin | Rheumatoid Arthritis | 5 | PM | 19371737 | 📋 | Decreased Activity of Neutrophils in the Presence of Diferuloylmethane (Curcumin) Involves Protein Kinase C Inhibition |
| Curcumin | Rheumatoid Arthritis | 2 | PM | 17671742 | 📋 | Curcumin Induces Apoptosis and Inhibits Prostaglandin E(2) Production in Synovial Fibroblasts of Patients With Rheumatoid Arthritis |
| Curcumin | Rheumatoid Arthritis | 4 | PM | 16807698 | 📋 | The Antioxidants Curcumin and Quercetin Inhibit Inflammatory Processes Associated With Arthritis |
| Curcumin | Schizophrenia | 1 | PM | 35655971 | 📋 | Role of Curcumin in the Management of Schizophrenia: A Narrative Review |
| Curcumin | Sciatic Nerve Injury | 2 | PM | 35870565 | 📋 | Proteomics reveals the key molecules involved in curcumin-induced protection against sciatic nerve injury in rats |
| Curcumin | Sciatic Nerve Injury | 1 | PM | 34902518 | 📋 | Curcumin enhances the proliferation and myelinization of Schwann cells through Runx2 to repair sciatic nerve injury |
| Curcumin | Sciatica | 3 | PM | 33201400 | 📋 | Protective Effects of Curcumin Against Paclitaxel-Induced Spinal Cord and Sciatic Nerve Injuries in Rats |
| Curcumin | Sciatica | 1 | PM | 31611748 | 📋 | Comparison of Melatonin and Curcumin Effect at the Light and Dark Periods on Regeneration of Sciatic Nerve Crush Injury in Rats |
| Curcumin | Sciatica | 2 | PM | 24317243 | 📋 | An Experimental Comparison of the Effects of Propolis, Curcumin, and Methylprednisolone on Crush Injuries of the Sciatic Nerve |
| Curcumin | Spinal Cord Injury | 16 | PM | 37076656 | 📋 | Curcumin can improve spinal cord injury by inhibiting DNA methylation |
| Curcumin | Spinal Cord Injury | 15 | PM | 36641925 | 📋 | Multiple mechanisms of curcumin targeting spinal cord injury |
| Curcumin | Spinal Cord Injury | 14 | PM | 35793928 | 📋 | Curcumin as a Promising Neuroprotective Agent for the Treatment of Spinal Cord Injury: A Review of the Literature |
| Curcumin | Spinal Cord Injury | 13 | PM | 35507337 | 📋 | The potential of curcumin for treating spinal cord injury: a meta-analysis study |
| Curcumin | Spinal Cord Injury | 1 | PM | 33980059 | 📋 | Curcumin Can Activate the Nrf2/HO-1 Signaling Pathway and Scavenge Free Radicals in Spinal Cord Injury Treatment |
| Curcumin | Spinal Cord Injury | 12 | PM | 33247374 | 📋 | Curcumin Improves Human Umbilical Cord-Derived Mesenchymal Stem Cell Survival via ERK1/2 Signaling and Promotes Motor Outcomes After Spinal Cord Injury |
| Curcumin | Spinal Cord Injury | 11 | PM | 33201400 | 📋 | Protective Effects of Curcumin Against Paclitaxel-Induced Spinal Cord and Sciatic Nerve Injuries in Rats |
| Curcumin | Spinal Cord Injury | 10 | PM | 32891672 | 📋 | Neuroprotective effects of Riluzole and Curcumin in human astrocytes and spinal cord white matter hypoxia |
| Curcumin | Spinal Cord Injury | 9 | PM | 27889433 | 📋 | The Protective Effect of Curcumin in Olfactory Ensheathing Cells Exposed to Hypoxia |
| Curcumin | Spinal Cord Injury | 8 | PM | 27298735 | 📋 | The Potential of Curcumin in Treatment of Spinal Cord Injury |
| Curcumin | Spinal Cord Injury | 4 | PM | 26729105 | 📋 | The Anti-Inflammatory Compound Curcumin Enhances Locomotor and Sensory Recovery After Spinal Cord Injury in Rats by Immunomodulation |
| Curcumin | Spinal Cord Injury | 2 | PM | 26387034 | 📋 | CISD2 Serves a Novel Role as a Suppressor of Nitric Oxide Signalling and Curcumin Increases CISD2 Expression in Spinal Cord Injuries |
| Curcumin | Spinal Cord Injury | 3 | PM | 25661742 | 📋 | Curcumin Improves Neural Function After Spinal Cord Injury by the Joint Inhibition of the Intracellular and Extracellular Components of Glial Scar |
| Curcumin | Spinal Cord Injury | 7 | PM | 22324804 | 📋 | Recovery From Spinal Cord Injury Using Naturally Occurring Antiinflammatory Compound Curcumin: Laboratory Investigation |
| Curcumin | Spinal Cord Injury | 6 | PM | 20535508 | 📋 | Curcumin Improves Early Functional Results After Experimental Spinal Cord Injury |
| Curcumin | Spinal Cord Injury | 5 | PM | 20018302 | 📋 | Curcumin Provides Neuroprotection After Spinal Cord Injury |
| Curcumin | Stress | 12 | PM | 33460863 | 📋 | Continuous exposure to amorphous formula of curcumin from the developmental stage facilitates anti-anxiety-like behavior and fear-extinction learning in rats |
| Curcumin | Stress | 2 | PM | 30542090 | 📋 | A Diet Enriched With Curcumin Promotes Resilience to Chronic Social Defeat Stress |
| Curcumin | Stress | 6 | PM | 25869755 | 📋 | Pretreatment With Curcumin Attenuates Anxiety While Strengthens Memory Performance After One Short Stress Experience in Male Rats |
| Curcumin | Stress | 10 | PM | 23876788 | 📋 | Antidepressant-like Effects of Curcumin in Chronic Mild Stress of Rats: Involvement of Its Anti-Inflammatory Action |
| Curcumin | Stress | 4 | PM | 20633542 | 📋 | GABAergic and Nitriergic Modulation by Curcumin for Its Antianxiety-Like Activity in Mice |
| Curcumin | Stress | 5 | PM | 19302828 | 📋 | Antidepressant-like Effects of Curcumin on Serotonergic Receptor-Coupled AC-cAMP Pathway in Chronic Unpredictable Mild Stress of Rats |
| Curcumin | Stroke | 8 | PM | 35914679 | 📋 | The action of curcumin against damage resulting from cerebral stroke: a systematic review |
| Curcumin | Stroke | 2 | PM | 29490624 | 📋 | Curcumin Prevents Strokes in Stroke-Prone Spontaneously Hypertensive Rats by Improving Vascular Endothelial Function |
| Curcumin | Stroke | 1 | PM | 26119880 | 📋 | Curcumin Attenuates Brain Edema in Mice With Intracerebral Hemorrhage Through Inhibition of AQP4 and AQP9 Expression |
| Curcumin | Stroke | 6 | PM | 25878600 | 📋 | Curcumin Pretreatment and Post-Treatment Both Improve the Antioxidative Ability of Neurons With Oxygen-Glucose Deprivation |
| Curcumin | Stroke | 7 | PM | 24788895 | 📋 | Epigenetic Impact of Curcumin on Stroke Prevention |
| Curcumin | Stroke | 5 | PM | 21158690 | 📋 | Neuroprotective and Neurotrophic Curcuminoids to Treat Stroke: A Translational Perspective |
| Curcumin | Stroke | 4 | PM | 19774461 | 📋 | Curcumin Improves Outcomes and Attenuates Focal Cerebral Ischemic Injury via Antiapoptotic Mechanisms in Rats |
| Curcumin | Stroke | 3 | PM | 18611416 | 📋 | Dose Dependence and Therapeutic Window for the Neuroprotective Effects of Curcumin in Thromboembolic Model of Rat |
| Curcumin | Subarachnoid Hemorrhage | 1 | PM | 27979493 | 📋 | Curcumin Attenuates Blood-Brain Barrier Disruption After Subarachnoid Hemorrhage in Mice |
| Curcumin | Subarachnoid Hemorrhage | 3 | PM | 26551062 | 📋 | Evidence for the Protective Effects of Curcumin Against Oxyhemoglobin-Induced Injury in Rat Cortical Neurons |
| Curcumin | Subarachnoid Hemorrhage | 2 | PM | 18752423 | 📋 | Curcumin Attenuates Vascular Inflammation and Cerebral Vasospasm After Subarachnoid Hemorrhage in Mice |
| Curcumin | Traumatic Brain Injury | 17 | PM | 38798711 | 📋 | Curcumin in the treatment of inflammation and oxidative stress responses in traumatic brain injury: a systematic review and meta-analysis |
| Curcumin | Traumatic Brain Injury | 16 | PM | 38562043 | 📋 | Curcumin Lowers the Accelerated Speed of Epileptogenesis by Traumatic Brain Injury |
| Curcumin | Traumatic Brain Injury | 15 | PM | 38032526 | 📋 | Curcumin alleviates traumatic brain injury induced by gas explosion through modulating gut microbiota and suppressing the LPS/TLR4/MyD88/NF-κB pathway |
| Curcumin | Traumatic Brain Injury | 14 | PM | 37478644 | 📋 | Curcumin ameliorates traumatic brain injury via C1ql3-mediated microglia M2 polarization |
| Curcumin | Traumatic Brain Injury | 13 | PM | 36872351 | 📋 | Curcumin Alleviates Oxidative stress, Neuroinflammation, and Promotes Behavioral Recovery after Traumatic Brain Injury |
| Curcumin | Traumatic Brain Injury | 12 | PM | 36055110 | 📋 | Protective effects of curcumin against traumatic brain injury |
| Curcumin | Traumatic Brain Injury | 11 | PM | 35080289 | 📋 | Curcumin suppress inflammatory response in traumatic brain injury via p38/MAPK signaling pathway |
| Curcumin | Traumatic Brain Injury | 10 | PM | 34080237 | 📋 | Effects of curcuminoids on inflammatory and oxidative stress biomarkers and clinical outcomes in critically ill patients: A randomized double-blind placebo-controlled trial |
| Curcumin | Traumatic Brain Injury | 9 | PM | 33548799 | 📋 | In Situ implantable, post-trauma microenvironment-responsive, ROS Depletion Hydrogels for the treatment of Traumatic brain injury |
| Curcumin | Traumatic Brain Injury | 8 | PM | 32502596 | 📋 | Curcumin Alleviates Neuroinflammation, Enhances Hippocampal Neurogenesis, and Improves Spatial Memory After Traumatic Brain Injury |
| Curcumin | Traumatic Brain Injury | 6 | PM | 24669820 | 📋 | Curcumin Attenuates Acute Inflammatory Injury by Inhibiting the TLR4/MyD88/NF-κB Signaling Pathway in Experimental Traumatic Brain Injury |
| Curcumin | Traumatic Brain Injury | 4 | PM | 23932920 | 📋 | Curcumin Pretreatment Attenuates Brain Lesion Size and Improves Neurological Function Following Traumatic Brain Injury in the Rat |
| Curcumin | Traumatic Brain Injury | 2 | PM | 20132469 | 📋 | Curcumin Attenuates Cerebral Edema Following Traumatic Brain Injury in Mice: A Possible Role for aquaporin-4? |
| Curcumin | Traumatic Brain Injury | 1 | PM | 20129497 | 📋 | Antioxidant Therapies for Traumatic Brain Injury |
| Curcumin | Traumatic Brain Injury | 3 | PM | 19393301 | 📋 | Dietary Curcumin Supplementation Counteracts Reduction in Levels of Molecules Involved in Energy Homeostasis After Brain Trauma |
| Curcumin | Traumatic Brain Injury | 5 | PM | 16364299 | 📋 | Dietary Curcumin Counteracts the Outcome of Traumatic Brain Injury on Oxidative Stress, Synaptic Plasticity, and Cognition |
| Curcumin | Traumatic Brain Injury | 7 | PM | 16266725 | 📋 | Prevention of Kainic Acid-Induced Changes in Nitric Oxide Level and Neuronal Cell Damage in the Rat Hippocampus by Manganese Complexes of Curcumin and Diacetylcurcumin |
| Curcumin | Trigeminal Neuralgia | 2 | PM | 37632838 | 📋 | Curcumin alleviates orofacial allodynia and improves cognitive impairment via regulating hippocampal synaptic plasticity in a mouse model of trigeminal neuralgia |
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