Substance | Condition | Seq | Src | PMID | Dtl | Title |
Crocetin | Alzheimer's Disease | 4 | PM | 38764638 | 📋 | ADME/PK Insights of Crocetin: A Molecule Having an Unusual Chemical Structure with Druglike Features |
Crocetin | Alzheimer's Disease | 1 | PM | 33404280 | 📋 | Crocetin promotes clearance of amyloid-β by inducing autophagy via the STK11/LKB1-mediated AMPK pathway |
Crocetin | Alzheimer's Disease | 2 | PM | 30450117 | 📋 | Crocetin attenuates inflammation and amyloid-β accumulation in APPsw transgenic mice |
Crocetin | Alzheimer's Disease | 3 | PM | 27865556 | 📋 | Trans-crocetin improves amyloid-β degradation in monocytes from Alzheimer's Disease patients |
Crocetin | Chronic Pain | 1 | PM | 33133459 | 📋 | Central H 2 histaminergic and alpha-2 adrenergic receptors involvement in crocetin-induced antinociception in orofacial formalin pain in rats |
Crocetin | Chronic Stress | 1 | PM | 29766828 | 📋 | Protective Effects of Crocetin on Depression-like Behavior Induced by Immobilization in Rat |
Crocetin | Dementia | 1 | PM | 29147836 | 📋 | Effects of Saffron and Its Constituents, crocin-1, crocin-2, and Crocetin on α-synuclein Fibrils |
Crocetin | Depression | 4 | PM | 37935859 | 📋 | Involvement of PI3K/AKT Pathway in the Rapid Antidepressant Effects of Crocetin in Mice with Depression-Like Phenotypes |
Crocetin | Depression | 3 | PM | 37506574 | 📋 | Saffron carotenoids reversed the UCMS-induced depression and anxiety in rats: Behavioral and biochemical parameters, and hippocampal BDNF/ERK/CREB and NR2B signaling markers |
Crocetin | Depression | 1 | PM | 33242618 | 📋 | Crocetin ameliorates chronic restraint stress-induced depression-like behaviors in mice by regulating MEK/ERK pathways and gut microbiota |
Crocetin | Depression | 2 | PM | 29766828 | 📋 | Protective Effects of Crocetin on Depression-like Behavior Induced by Immobilization in Rat |
Crocetin | Glioblastoma | 1 | PM | 31936544 | 📋 | Crocetin Extracted from Saffron Shows Antitumor Effects in Models of Human Glioblastoma |
Crocetin | Ischemic Stroke | 3 | PM | 37001492 | 📋 | Crocetin Regulates Functions of Neural Stem Cells to Generate New Neurons for Cerebral Ischemia Recovery |
Crocetin | Ischemic Stroke | 2 | PM | 36681688 | 📋 | Crocetin antagonizes parthanatos in ischemic stroke via inhibiting NOX2 and preserving mitochondrial hexokinase-I |
Crocetin | Ischemic Stroke | 1 | PM | 35991882 | 📋 | Crocins for Ischemic Stroke: A Review of Current Evidence |
Crocetin | Neurodegenerative Disease | 1 | PM | 29147836 | 📋 | Effects of Saffron and Its Constituents, crocin-1, crocin-2, and Crocetin on α-synuclein Fibrils |
Crocetin | Neuroinflammation | 1 | PM | 29217355 | 📋 | Crocetin attenuates spared nerve injury-induced neuropathic pain in mice |
Crocetin | Neuropathic Pain | 1 | PM | 29217355 | 📋 | Crocetin attenuates spared nerve injury-induced neuropathic pain in mice |
Crocetin | Orofacial Pain | 1 | PM | 33133459 | 📋 | Central H 2 histaminergic and alpha-2 adrenergic receptors involvement in crocetin-induced antinociception in orofacial formalin pain in rats |
Crocetin | Parkinson's Disease | 2 | PM | 34224829 | 📋 | Saffron ameliorated motor symptoms, short life span and retinal degeneration in Parkinson's disease fly models |
Crocetin | Parkinson's Disease | 1 | PM | 33101635 | 📋 | Crocetin Alleviates Inflammation in MPTP-Induced Parkinson's Disease Models through Improving Mitochondrial Functions |
Crocetin | Spinal Cord Injury | 2 | PM | 29217355 | 📋 | Crocetin attenuates spared nerve injury-induced neuropathic pain in mice |
Crocetin | Spinal Cord Injury | 1 | PM | 28770439 | 📋 | Crocetin Potentiates Neurite Growth in Hippocampal Neurons and Facilitates Functional Recovery in Rats with Spinal Cord Injury |
Crocetin | Traumatic Brain Injury | 1 | PM | 38433503 | 📋 | Crocetin protects mouse brain from apoptosis in traumatic brain injury model through activation of autophagy |