| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Catalpol | Alzheimer's Disease | 4 | PM | 37336148 | 📋 | Catalpol rescues cognitive deficits by attenuating amyloid β plaques and neuroinflammation |
| Catalpol | Alzheimer's Disease | 3 | PM | 36595161 | 📋 | Catalpol Mitigates Alzheimer's Disease Progression by Promoting the Expression of Neural Stem Cell Exosomes Released miR-138-5p |
| Catalpol | Alzheimer's Disease | 2 | PM | 35815283 | 📋 | Effects of Catalpol on Alzheimer's Disease and Its Mechanisms |
| Catalpol | Alzheimer's Disease | 1 | PM | 34216649 | 📋 | Therapeutic potential of catalpol and geniposide in Alzheimer's and Parkinson's diseases: A snapshot of their underlying mechanisms |
| Catalpol | Chronic Pain | 1 | PM | 36353492 | 📋 | Catalpol ameliorates CFA-induced inflammatory pain by targeting spinal cord and peripheral inflammation |
| Catalpol | Demyelinating Disease | 1 | PM | 36482934 | 📋 | Catalpol Regulates Oligodendrocyte Regeneration and Remyelination by Activating the GEF-Cdc42/Rac1 Signaling Pathway in EAE Mice |
| Catalpol | Depression | 6 | PM | 37551177 | 📋 | Catalpol Alleviates Depression by Inhibiting NLRP3 Inflammasome via TLR4/MAPK/NF-Kb Pathway |
| Catalpol | Depression | 5 | PM | 35668334 | 📋 | Catalpol Exerts Antidepressant-Like Effects by Enhancing Anti-oxidation and Neurotrophy and Inhibiting Neuroinflammation via Activation of HO-1 |
| Catalpol | Depression | 4 | PM | 34500039 | 📋 | Antidepressant effect of catalpol on corticosterone-induced depressive-like behavior involves the inhibition of HPA axis hyperactivity, central inflammation and oxidative damage probably via dual regulation of NF-κB and Nrf2 |
| Catalpol | Depression | 1 | PM | 34358633 | 📋 | Catalpol weakens depressive-like behavior in mice with streptozotocin-induced hyperglycemia via PI3K/AKT/Nrf2/HO-1 signaling pathway |
| Catalpol | Depression | 2 | PM | 34332921 | 📋 | Antidepressant mechanism of catalpol: Involvement of the PI3K/Akt/Nrf2/HO-1 signaling pathway |
| Catalpol | Depression | 3 | PM | 34103482 | 📋 | Catalpol ameliorates depressive-like behaviors in CUMS mice via oxidative stress-mediated NLRP3 inflammasome and neuroinflammation |
| Catalpol | Ischemic Stroke | 3 | PM | 38522312 | 📋 | Catalpol attenuates ischemic stroke by promoting neurogenesis and angiogenesis via the SDF-1α/CXCR4 pathway |
| Catalpol | Ischemic Stroke | 2 | PM | 37439957 | 📋 | Catalpol Alleviates Ischemic Stroke Through Promoting Angiogenesis and Facilitating Proliferation and Differentiation of Neural Stem Cells via the VEGF-A/KDR Pathway |
| Catalpol | Ischemic Stroke | 1 | PM | 34795412 | 📋 | Catalpol improves impaired neurovascular unit in ischemic stroke rats via enhancing VEGF-PI3K/AKT and VEGF-MEK1/2/ERK1/2 signaling |
| Catalpol | Multiple Sclerosis | 1 | PM | 33708131 | 📋 | Effect and Mechanism of Catalpol on Remyelination via Regulation of the NOTCH1 Signaling Pathway |
| Catalpol | Neonatal Encephalopathy | 1 | PM | 38341076 | 📋 | Catalpol alleviates hypoxia ischemia-induced brain damage by inhibiting ferroptosis through the PI3K/NRF2/system Xc-/GPX4 axis in neonatal rats |
| Catalpol | Neuroinflammation | 6 | PM | 37926114 | 📋 | Catalpol rescues LPS-induced cognitive impairment via inhibition of NF-Κb-regulated neuroinflammation and up-regulation of TrkB-mediated BDNF secretion in mice |
| Catalpol | Neuroinflammation | 5 | PM | 37551177 | 📋 | Catalpol Alleviates Depression by Inhibiting NLRP3 Inflammasome via TLR4/MAPK/NF-Kb Pathway |
| Catalpol | Neuroinflammation | 4 | PM | 37336148 | 📋 | Catalpol rescues cognitive deficits by attenuating amyloid β plaques and neuroinflammation |
| Catalpol | Neuroinflammation | 3 | PM | 36315368 | 📋 | Catalpol Ameliorates Oxidative Stress and Neuroinflammation after Traumatic Brain Injury in Rats |
| Catalpol | Neuroinflammation | 2 | PM | 35668334 | 📋 | Catalpol Exerts Antidepressant-Like Effects by Enhancing Anti-oxidation and Neurotrophy and Inhibiting Neuroinflammation via Activation of HO-1 |
| Catalpol | Neuroinflammation | 1 | PM | 34103482 | 📋 | Catalpol ameliorates depressive-like behaviors in CUMS mice via oxidative stress-mediated NLRP3 inflammasome and neuroinflammation |
| Catalpol | Neurotoxicity | 1 | PM | 35545014 | 📋 | Catalpol Alleviates Isoflurane-Induced Hippocampal Learning and Memory Dysfunction and Neuropathological Changes in Aged Mice |
| Catalpol | Parkinson's Disease | 1 | PM | 34216649 | 📋 | Therapeutic potential of catalpol and geniposide in Alzheimer's and Parkinson's diseases: A snapshot of their underlying mechanisms |
| Catalpol | Rheumatoid Arthritis | 1 | PM | 34913284 | 📋 | Catalpol Inhibits Tregs-to-Th17 Cell Transdifferentiation by Up-Regulating Let-7g-5p to Reduce STAT3 Protein Levels |
| Catalpol | Spinal Cord Injury | 2 | PM | 35873542 | 📋 | Catalpol as a Component of Rehmannia glutinosa Protects Spinal Cord Injury by Inhibiting Endoplasmic Reticulum Stress-Mediated Neuronal Apoptosis |
| Catalpol | Spinal Cord Injury | 1 | PM | 33628189 | 📋 | Catalpol Protects Against Spinal Cord Injury in Mice Through Regulating MicroRNA-142-Mediated HMGB1/TLR4/NF-κB Signaling Pathway |
| Catalpol | Stroke | 1 | PM | 33505489 | 📋 | Network Pharmacology-Based Prediction of Catalpol and Mechanisms against Stroke |
| Catalpol | Traumatic Brain Injury | 1 | PM | 36315368 | 📋 | Catalpol Ameliorates Oxidative Stress and Neuroinflammation after Traumatic Brain Injury in Rats |
