| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Asiatic Acid | Alzheimer's Disease | 1 | PM | 32721993 | 📋 | Combining In Silico and In Vitro Studies to Evaluate the Acetylcholinesterase Inhibitory Profile of Different Accessions and the Biomarker Triterpenes of Centella asiatica |
| Asiatic Acid | Alzheimer's Disease | 2 | PM | 30671870 | 📋 | Asiatic Acid Attenuated Aluminum Chloride-Induced Tau Pathology, Oxidative Stress and Apoptosis Via AKT/GSK-3β Signaling Pathway in Wistar Rats |
| Asiatic Acid | Alzheimer's Disease | 4 | PM | 30017668 | 📋 | Asiatic acid protects differentiated PC12 cells from Aβ25-35-induced apoptosis and tau hyperphosphorylation via regulating PI3K/Akt/GSK-3β signaling |
| Asiatic Acid | Alzheimer's Disease | 6 | PM | 28930619 | 📋 | Asiatic acid nullified aluminium toxicity in in vitro model of Alzheimer's disease |
| Asiatic Acid | Alzheimer's Disease | 5 | PM | 28930532 | 📋 | Neuroprotective role of Asiatic acid in aluminium chloride induced rat model of Alzheimer's disease |
| Asiatic Acid | Alzheimer's Disease | 3 | PM | 20553006 | 📋 | Withanolide A and asiatic acid modulate multiple targets associated with amyloid-beta precursor protein processing and amyloid-beta protein clearance |
| Asiatic Acid | Epilepsy | 1 | PM | 33802221 | 📋 | Asiatic Acid Prevents Cognitive Deficits by Inhibiting Calpain Activation and Preserving Synaptic and Mitochondrial Function in Rats with Kainic Acid-Induced Seizure |
| Asiatic Acid | Glioblastoma | 1 | PM | 28205096 | 📋 | Pharmacological effects of asiatic acid in glioblastoma cells under hypoxia |
| Asiatic Acid | Glioblastoma | 2 | PM | 25252179 | 📋 | Asiatic acid induces endoplasmic reticulum stress and apoptotic death in glioblastoma multiforme cells both in vitro and in vivo |
| Asiatic Acid | Glioma | 1 | PM | 21826202 | 📋 | Asiatic acid inhibits pro-angiogenic effects of VEGF and human gliomas in endothelial cell culture models |
| Asiatic Acid | Neonatal Encephalopathy | 1 | PM | 38027402 | 📋 | Asiatic acid increased locomotor and head width by inducing brain-derived neurotrophic factor in intrauterine hypoxia-exposed zebrafish |
| Asiatic Acid | Neurodegenerative Disease | 1 | PM | 32949562 | 📋 | Blood-Brain Barrier Permeability of Asiaticoside, Madecassoside and Asiatic Acid in Porcine Brain Endothelial Cell Model |
| Asiatic Acid | Neuroinflammation | 3 | PM | 30971058 | 📋 | Asiatic Acid Protects Dopaminergic Neurons from Neuroinflammation by Suppressing Mitochondrial Ros Production |
| Asiatic Acid | Neuroinflammation | 2 | PM | 29354820 | 📋 | Asiatic acid suppresses neuroinflammation in BV2 microglia via modulation of the Sirt1/NF-κB signaling pathway |
| Asiatic Acid | Neuroinflammation | 1 | PM | 29228978 | 📋 | Asiatic acid attenuates methamphetamine-induced neuroinflammation and neurotoxicity through blocking of NF-kB/STAT3/ERK and mitochondria-mediated apoptosis pathway |
| Asiatic Acid | Neurological Disorders | 1 | PM | 37180926 | 📋 | Neuroprotective mechanisms of Asiatic acid |
| Asiatic Acid | Neuronal Damage | 1 | PM | 22296759 | 📋 | Asiatic acid protects primary neurons against C2-ceramide-induced apoptosis |
| Asiatic Acid | Neurotoxicity | 1 | PM | 35554794 | 📋 | Asiatic acid attenuates aluminium chloride-induced behavioral changes, neuronal loss and astrocyte activation in rats |
| Asiatic Acid | Neurotoxicity | 2 | PM | 29228978 | 📋 | Asiatic acid attenuates methamphetamine-induced neuroinflammation and neurotoxicity through blocking of NF-kB/STAT3/ERK and mitochondria-mediated apoptosis pathway |
| Asiatic Acid | Neurotoxicity | 3 | PM | 28700628 | 📋 | Asiatic acid protects against cognitive deficits and reductions in cell proliferation and survival in the rat hippocampus caused by 5-fluorouracil chemotherapy |
| Asiatic Acid | Neurotoxicity | 4 | PM | 27213437 | 📋 | Asiatic Acid Prevents the Deleterious Effects of Valproic Acid on Cognition and Hippocampal Cell Proliferation and Survival |
| Asiatic Acid | Parkinson's Disease | 4 | PM | 30971058 | 📋 | Asiatic Acid Protects Dopaminergic Neurons from Neuroinflammation by Suppressing Mitochondrial Ros Production |
| Asiatic Acid | Parkinson's Disease | 1 | PM | 28181071 | 📋 | Neurotrophic Effect of Asiatic acid, a Triterpene of Centella asiatica Against Chronic 1-Methyl 4-Phenyl 1, 2, 3, 6-Tetrahydropyridine Hydrochloride/Probenecid Mouse Model of Parkinson's disease: The Role of MAPK, PI3K-Akt-GSK3β and mTOR Signalling Pathways |
| Asiatic Acid | Parkinson's Disease | 3 | PM | 26999333 | 📋 | Asiatic acid attenuated apoptotic and inflammatory stress in the striatum of MPTP-treated mice |
| Asiatic Acid | Parkinson's Disease | 2 | PM | 26856988 | 📋 | Neuroprotective effect of asiatic acid on rotenone-induced mitochondrial dysfunction and oxidative stress-mediated apoptosis in differentiated SH-SYS5Y cells |
| Asiatic Acid | Rheumatoid Arthritis | 1 | PM | 38477392 | 📋 | Asiatic acid inhibits rheumatoid arthritis fibroblast-like synoviocyte growth through the Nrf2/HO-1/NF-κB signaling pathway |
| Asiatic Acid | Seizures | 1 | PM | 33802221 | 📋 | Asiatic Acid Prevents Cognitive Deficits by Inhibiting Calpain Activation and Preserving Synaptic and Mitochondrial Function in Rats with Kainic Acid-Induced Seizure |
| Asiatic Acid | Seizures | 2 | PM | 29156327 | 📋 | Asiatic acid and maslinic acid attenuated kainic acid-induced seizure through decreasing hippocampal inflammatory and oxidative stress |
| Asiatic Acid | Spinal Cord Injury | 1 | PM | 27605220 | 📋 | Protective Effects of Asiatic Acid Against Spinal Cord Injury-Induced Acute Lung Injury in Rats |
| Asiatic Acid | Spinal Cord Injury | 2 | PM | 27593768 | 📋 | Effect of Asiatic Acid on the Treatment of Spinal Cord Injury: An Experimental Study in Rats |
| Asiatic Acid | Spinal Cord Injury | 3 | PM | 27153777 | 📋 | Neuroprotective effect of asiatic acid against spinal cord injury in rats |
| Asiatic Acid | Stroke | 2 | PM | 25087961 | 📋 | Neuroprotective effect of asiatic acid in rat model of focal embolic stroke |
| Asiatic Acid | Stroke | 1 | PM | 22511009 | 📋 | Asiatic acid attenuates infarct volume, mitochondrial dysfunction, and matrix metalloproteinase-9 induction after focal cerebral ischemia |
