| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Arctigenin | Alzheimer's Disease | 3 | PM | 38104254 | 📋 | Arctigenin attenuated spatial memory impairment in pR5 mice by regulating mitochondrial energy metabolism |
| Arctigenin | Alzheimer's Disease | 2 | PM | 27224270 | 📋 | Arctigenin Attenuates Learning and Memory Deficits through PI3k/Akt/GSK-3β Pathway Reducing Tau Hyperphosphorylation in Aβ-Induced AD Mice |
| Arctigenin | Alzheimer's Disease | 1 | PM | 23926267 | 📋 | Arctigenin effectively ameliorates memory impairment in Alzheimer's disease model mice targeting both β-amyloid production and clearance |
| Arctigenin | Chronic Stress | 1 | PM | 32964428 | 📋 | Arctigenin protects against depression by inhibiting microglial activation and neuroinflammation via HMGB1/TLR4/NF-κB and TNF-α/TNFR1/NF-κB pathways |
| Arctigenin | Depression | 2 | PM | 32964428 | 📋 | Arctigenin protects against depression by inhibiting microglial activation and neuroinflammation via HMGB1/TLR4/NF-κB and TNF-α/TNFR1/NF-κB pathways |
| Arctigenin | Depression | 1 | PM | 30597190 | 📋 | Repeated arctigenin treatment produces antidepressant- and anxiolytic-like effects in mice |
| Arctigenin | Diabetic Neuropathy | 1 | PM | 37170684 | 📋 | Arctigenin improves neuropathy via ameliorating apoptosis and modulating autophagy in streptozotocin-induced diabetic mice |
| Arctigenin | Encephalitis | 1 | PM | 24780919 | 📋 | Antioxidants: Potential Antiviral Agents for Japanese Encephalitis Virus Infection |
| Arctigenin | Glioblastoma | 1 | PM | 33015162 | 📋 | Arctigenin Inhibits Glioblastoma Proliferation through the AKT/mTOR Pathway and Induces Autophagy |
| Arctigenin | Ischemic Stroke | 1 | PM | 28888980 | 📋 | Arctigenin attenuates ischemic stroke via SIRT1-dependent inhibition of NLRP3 inflammasome |
| Arctigenin | Multiple Sclerosis | 2 | PM | 34349758 | 📋 | Arctigenin Exerts Neuroprotective Effect by Ameliorating Cortical Activities in Experimental Autoimmune Encephalomyelitis In Vivo |
| Arctigenin | Multiple Sclerosis | 1 | PM | 26440666 | 📋 | Arctigenin Suppress Th17 Cells and Ameliorates Experimental Autoimmune Encephalomyelitis Through AMPK and PPAR-γ/ROR-γt Signaling |
| Arctigenin | Neuroinflammation | 1 | PM | 35731324 | 📋 | Preventive effects of arctigenin from Arctium lappa L against LPS-induced neuroinflammation and cognitive impairments in mice |
| Arctigenin | Neuroinflammation | 4 | PM | 35541453 | 📋 | Neuroprotective effect of arctigenin against neuroinflammation and oxidative stress induced by rotenone |
| Arctigenin | Neuroinflammation | 3 | PM | 32964428 | 📋 | Arctigenin protects against depression by inhibiting microglial activation and neuroinflammation via HMGB1/TLR4/NF-κB and TNF-α/TNFR1/NF-κB pathways |
| Arctigenin | Neuroinflammation | 2 | PM | 22972486 | 📋 | Arctigenin protects focal cerebral ischemia-reperfusion rats through inhibiting neuroinflammation |
| Arctigenin | Neurological Disorders | 1 | PM | 37236381 | 📋 | Effect of arctigenin on neurological diseases: A review |
| Arctigenin | Neuronal Damage | 1 | PM | 27389368 | 📋 | Arctigenin Confers Neuroprotection Against Mechanical Trauma Injury in Human Neuroblastoma SH-SY5Y Cells by Regulating miRNA-16 and miRNA-199a Expression to Alleviate Inflammation |
| Arctigenin | Neurotoxicity | 1 | PM | 28260103 | 📋 | Protective effect of arctigenin on ethanol-induced neurotoxicity in PC12 cells |
| Arctigenin | Neurotoxicity | 3 | PM | 24414307 | 📋 | Protective effect of arctigenin against MPP+ and MPTP-induced neurotoxicity |
| Arctigenin | Neurotoxicity | 2 | PM | 24025424 | 📋 | Neuroprotective effect of arctigenin via upregulation of P-CREB in mouse primary neurons and human SH-SY5Y neuroblastoma cells |
| Arctigenin | Parkinson's Disease | 1 | PM | 35541453 | 📋 | Neuroprotective effect of arctigenin against neuroinflammation and oxidative stress induced by rotenone |
| Arctigenin | Rheumatoid Arthritis | 2 | PM | 25609147 | 📋 | The effects of arctigenin on human rheumatoid arthritis fibroblast-like synoviocytes |
| Arctigenin | Rheumatoid Arthritis | 1 | PM | 22387094 | 📋 | Arctigenin suppresses receptor activator of nuclear factor κB ligand (RANKL)-mediated osteoclast differentiation in bone marrow-derived macrophages |
| Arctigenin | Stress | 1 | PM | 30597190 | 📋 | Repeated arctigenin treatment produces antidepressant- and anxiolytic-like effects in mice |
| Arctigenin | Subarachnoid Hemorrhage | 1 | PM | 26539501 | 📋 | Arctigenin, a Potent Ingredient of Arctium lappa L., Induces Endothelial Nitric Oxide Synthase and Attenuates Subarachnoid Hemorrhage-Induced Vasospasm through PI3K/Akt Pathway in a Rat Model |
