| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Spirulina | Diabetes Type 2 | 5 | PM | 36598187 | 📋 | A randomized, double-blind placebo-controlled add-on trial to assess the efficacy, safety, and anti-atherogenic effect of spirulina platensis in patients with inadequately controlled type 2 diabetes mellitus |
| Spirulina | Diabetes Type 2 | 4 | PM | 34821103 | 📋 | [The effects of aerobic exercise plus spirulina polysaccharide supplement on learning and memory function of diabetes rats and its mechanism] |
| Spirulina | Diabetes Type 2 | 2 | PM | 34178867 | 📋 | The effect of spirulina on type 2 diabetes: a systematic review and meta-analysis |
| Spirulina | Diabetes Type 2 | 1 | PM | 32517842 | 📋 | Effects of Spirulina platensis on Insulin Secretion, DPP-IV Activity and Both Carbohydrate Digestion and Absorption Indicate Potential as an Adjunctive Therapy for Diabetes |
| Spirulina | Diabetes Type 2 | 3 | PM | 25112514 | 📋 | Selenium-enriched Spirulina protects INS-1E pancreatic beta cells from human islet amyloid polypeptide-induced apoptosis through suppression of ROS-mediated mitochondrial dysfunction and PI3/AKT pathway |
| Spirulina | Excessive Weight | 1 | PM | 32201580 | 📋 | Effects of spirulina on weight loss and blood lipids: a review |
| Spirulina | Glucose Metabolism Disorder | 2 | PM | 36598187 | 📋 | A randomized, double-blind placebo-controlled add-on trial to assess the efficacy, safety, and anti-atherogenic effect of spirulina platensis in patients with inadequately controlled type 2 diabetes mellitus |
| Spirulina | Glucose Metabolism Disorder | 1 | PM | 22254118 | 📋 | The effect of Spirulina platensis versus soybean on insulin resistance in HIV-infected patients: a randomized pilot study |
| Spirulina | Hypercholesterolemia | 5 | PM | 29736642 | 📋 | Therapeutic effect of the alkaloid extract of the cyanobacterium Spirulina platensis on the lipid profile of hypercholesterolemic male rabbits |
| Spirulina | Hypercholesterolemia | 3 | PM | 27478549 | 📋 | The influence of obesity on the effects of spirulina supplementation in the human metabolic response of Korean elderly |
| Spirulina | Hypercholesterolemia | 1 | PM | 26433766 | 📋 | A systematic review and meta-analysis of the impact of Spirulina supplementation on plasma lipid concentrations |
| Spirulina | Hypercholesterolemia | 4 | PM | 25481402 | 📋 | Effects of fish oil and spirulina on oxidative stress and inflammation in hypercholesterolemic hamsters |
| Spirulina | Hypercholesterolemia | 2 | PM | 18714150 | 📋 | A randomized double-blind, placebo-controlled study to establish the effects of spirulina in elderly Koreans |
| Spirulina | Hyperglycemia | 1 | PM | 32982392 | 📋 | Oral Spirulina Platensis Attenuates Hyperglycemia and Exhibits Antinociceptive Effect in Streptozotocin-Induced Diabetic Neuropathy Rat Model |
| Spirulina | Hyperglycemia | 2 | PM | 29091744 | 📋 | Effects of Spirulina platensis on lipid peroxidation, antioxidant defenses, and tissue damage in kidney of alloxan-induced diabetic rats |
| Spirulina | Hyperglycemia | 3 | PM | 27865613 | 📋 | Hyperglycemia, oxidative stress, liver damage and dysfunction in alloxan-induced diabetic rat are prevented by Spirulina supplementation |
| Spirulina | Hyperlipidemia | 4 | PM | 31334136 | 📋 | Dose Effects of Orally Administered Spirulina Suspension on Colonic Microbiota in Healthy Mice |
| Spirulina | Hyperlipidemia | 1 | PM | 31175915 | 📋 | Polyunsaturated fatty acids from microalgae Spirulina platensis modulates lipid metabolism disorders and gut microbiota in high-fat diet rats |
| Spirulina | Hyperlipidemia | 3 | PM | 30551559 | 📋 | Regulatory Efficacy of Spirulina platensis Protease Hydrolyzate on Lipid Metabolism and Gut Microbiota in High-Fat Diet-Fed Rats |
| Spirulina | Hyperlipidemia | 2 | PM | 2117648 | 📋 | Effects of Spirulina platensis on plasma lipoprotein lipase activity in fructose-induced hyperlipidemic rats |
| Spirulina | Hypertriglyceridemia | 1 | PM | 26433766 | 📋 | A systematic review and meta-analysis of the impact of Spirulina supplementation on plasma lipid concentrations |
| Spirulina | Hypertriglyceridemia | 2 | PM | 23754631 | 📋 | The hypolipidaemic effects of Spirulina (Arthrospira platensis) supplementation in a Cretan population: a prospective study |
| Spirulina | Insulin Resistance | 4 | PM | 34616107 | 📋 | Spirulina platensis and its ingredient biopterin glucoside improved insulin sensitivity in non-alcoholic steatohepatitis model |
| Spirulina | Insulin Resistance | 1 | PM | 28617537 | 📋 | Spirulina maxima improves insulin sensitivity, lipid profile, and total antioxidant status in obese patients with well-treated hypertension: a randomized double-blind placebo-controlled study |
| Spirulina | Insulin Resistance | 3 | PM | 27069726 | 📋 | Spirulina versicolor improves insulin sensitivity and attenuates hyperglycemia-mediated oxidative stress in fructose-fed rats |
| Spirulina | Insulin Resistance | 2 | PM | 22254118 | 📋 | The effect of Spirulina platensis versus soybean on insulin resistance in HIV-infected patients: a randomized pilot study |
| Spirulina | Metabolic Disorders | 3 | PM | 38251049 | 📋 | The Effects of Spirulina Supplementation on Cardiometabolic Risk Factors: A Narrative Review |
| Spirulina | Metabolic Disorders | 2 | PM | 34399508 | 📋 | Spirulina platensis polysaccharides attenuate lipid and carbohydrate metabolism disorder in high-sucrose and high-fat diet-fed rats in association with intestinal microbiota |
| Spirulina | Metabolic Disorders | 1 | PM | 33572056 | 📋 | Edible Microalgae and Their Bioactive Compounds in the Prevention and Treatment of Metabolic Alterations |
| Spirulina | Metabolic Syndrome | 5 | PM | 33348926 | 📋 | Are There Any Beneficial Effects of Spirulina Supplementation for Metabolic Syndrome Components in Postmenopausal Women? |
| Spirulina | Metabolic Syndrome | 1 | PM | 31359513 | 📋 | The effects of spirulina on glycemic control and serum lipoproteins in patients with metabolic syndrome and related disorders: A systematic review and meta-analysis of randomized controlled trials |
| Spirulina | Metabolic Syndrome | 4 | PM | 30670232 | 📋 | The effects of Spirulina supplementation on metabolic syndrome components, its liver manifestation and related inflammatory markers: A systematic review |
| Spirulina | Metabolic Syndrome | 3 | PM | 29958046 | 📋 | Putative Effect of Spirulina Extract on Enzyme Activities Participating in Lipid and Carbohydrate Digestion Processes |
| Spirulina | Metabolic Syndrome | 2 | PM | 22444524 | 📋 | Spirulina improves non-alcoholic steatohepatitis, visceral fat macrophage aggregation, and serum leptin in a mouse model of metabolic syndrome |
| Spirulina | Mitochondrial Dysfunction | 2 | PM | 37416477 | 📋 | Restoration of mitochondrial function by Spirulina polysaccharide via upregulated SOD2 in aging fibroblasts |
| Spirulina | Mitochondrial Dysfunction | 1 | PM | 25112514 | 📋 | Selenium-enriched Spirulina protects INS-1E pancreatic beta cells from human islet amyloid polypeptide-induced apoptosis through suppression of ROS-mediated mitochondrial dysfunction and PI3/AKT pathway |
| Spirulina | Obesity | 17 | PM | 38694088 | 📋 | Amino acid HPLC-FLD analysis of spirulina and its protective mechanism against the combination of obesity and colitis in wistar rats |
| Spirulina | Obesity | 16 | PM | 38068748 | 📋 | Spirulina Supplementation with High-Intensity Interval Training Decreases Adipokines Levels and Cardiovascular Risk Factors in Men with Obesity |
| Spirulina | Obesity | 15 | PM | 37893541 | 📋 | Chromatographic Analyses of Spirulina (Arthrospira platensis) and Mechanism of Its Protective Effects against Experimental Obesity and Hepatic Steatosis in Rats |
| Spirulina | Obesity | 13 | PM | 35037261 | 📋 | High-intensity interval training along with spirulina algae consumption and caloric restriction ameliorated the Nrf1/Tfam/Mgmt and ATP5A1 pathway in the heart tissue of obese rats |
| Spirulina | Obesity | 14 | PM | 34367461 | 📋 | Spirulina platensis Consumption Prevents Obesity and Improves the Deleterious Effects on Intestinal Reactivity in Rats Fed a Hypercaloric Diet |
| Spirulina | Obesity | 1 | PM | 32685091 | 📋 | Potential Therapeutic Role of Dietary Supplementation with Spirulina platensis on the Erectile Function of Obese Rats Fed a Hypercaloric Diet |
| Spirulina | Obesity | 12 | PM | 32207345 | 📋 | Spirulina reduces diet-induced obesity through downregulation of lipogenic genes expression in Psammomys obesus |
| Spirulina | Obesity | 4 | PM | 31780031 | 📋 | Effects of Spirulina supplementation on obesity: A systematic review and meta-analysis of randomized clinical trials |
| Spirulina | Obesity | 8 | PM | 31220177 | 📋 | Anti-obesity effects of Spirulina platensis protein hydrolysate by modulating brain-liver axis in high-fat diet fed mice |
| Spirulina | Obesity | 6 | PM | 31067674 | 📋 | Hypolipidemic Effect of Arthrospira ( Spirulina) maxima Supplementation and a Systematic Physical Exercise Program in Overweight and Obese Men: A Double-Blind, Randomized, and Crossover Controlled Trial |
| Spirulina | Obesity | 11 | PM | 30551559 | 📋 | Regulatory Efficacy of Spirulina platensis Protease Hydrolyzate on Lipid Metabolism and Gut Microbiota in High-Fat Diet-Fed Rats |
| Spirulina | Obesity | 7 | PM | 30275428 | 📋 | Effect of Arthrospira (Spirulina) maxima Supplementation and a Systematic Physical Exercise Program on the Body Composition and Cardiorespiratory Fitness of Overweight or Obese Subjects: A Double-Blind, Randomized, and Crossover Controlled Trial |
| Spirulina | Obesity | 5 | PM | 30219433 | 📋 | Spirulina platensis effectively ameliorates anthropometric measurements and obesity-related metabolic disorders in obese or overweight healthy individuals: A randomized controlled trial |
| Spirulina | Obesity | 10 | PM | 30178808 | 📋 | Anti-obesity effects of Spirulina maxima in high fat diet induced obese rats via the activation of AMPK pathway and SIRT1 |
| Spirulina | Obesity | 9 | PM | 29865208 | 📋 | Spirulina maxima Extract Reduces Obesity through Suppression of Adipogenesis and Activation of Browning in 3T3-L1 Cells and High-Fat Diet-Induced Obese Mice |
| Spirulina | Obesity | 3 | PM | 28617537 | 📋 | Spirulina maxima improves insulin sensitivity, lipid profile, and total antioxidant status in obese patients with well-treated hypertension: a randomized double-blind placebo-controlled study |
| Spirulina | Obesity | 2 | PM | 25821309 | 📋 | Combination of Spirulina with glycyrrhizin prevents cognitive dysfunction in aged obese rats |
| Spirulina | Overweight | 1 | PM | 32967062 | 📋 | Spirulina supplementation and anthropometric indices: A systematic review and meta-analysis of controlled clinical trials |
| Spirulina | Overweight | 2 | PM | 30275428 | 📋 | Effect of Arthrospira (Spirulina) maxima Supplementation and a Systematic Physical Exercise Program on the Body Composition and Cardiorespiratory Fitness of Overweight or Obese Subjects: A Double-Blind, Randomized, and Crossover Controlled Trial |
| Spirulina | Postprandial Hyperglycemia | 1 | PM | 36557218 | 📋 | Short-Term Effects of Spirulina Consumption on Glycemic Responses and Blood Pressure in Healthy Young Adults: Results from Two Randomized Clinical Trials |
