| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Roselle | Diabetes Type 2 | 1 | PM | 26632284 | 📋 | Medicinal Plants Traditionally Used for Treatment of Obesity and Diabetes Mellitus - Screening for Pancreatic Lipase and α-Amylase Inhibition |
| Roselle | Excessive Weight | 1 | PM | 31935957 | 📋 | A Randomized, Double-Blind, Placebo Controlled Trial to Determine the Effectiveness a Polyphenolic Extract ( Hibiscus sabdariffa and Lippia citriodora) in the Reduction of Body Fat Mass in Healthy Subjects |
| Roselle | Hypercholesterolemia | 2 | PM | 34927694 | 📋 | A systematic review and meta-analysis of the effects of Hibiscus sabdariffa on blood pressure and cardiometabolic markers |
| Roselle | Hypercholesterolemia | 1 | PM | 28049927 | 📋 | Hypolipidemic and Hypocholesterolemic Effect of Roselle (Hibiscus Sabdariffa L.) Seeds Oil in Experimental Male Rats |
| Roselle | Hyperglycemia | 1 | PM | 25965053 | 📋 | Hibiscus Sabdariffa Calyx Palliates Insulin Resistance, Hyperglycemia, Dyslipidemia and Oxidative Rout in Fructose-Induced Metabolic Syndrome Rats |
| Roselle | Hyperlipidemia | 4 | PM | 34281481 | 📋 | Delphinidin-3-sambubioside from Hibiscus sabdariffa. L attenuates hyperlipidemia in high fat diet-induced obese rats and oleic acid-induced steatosis in HepG2 cells |
| Roselle | Hyperlipidemia | 5 | PM | 32156406 | 📋 | The antidiabetic and antilipidemic effects of Hibiscus sabdariffa: A systematic review and meta-analysis of randomized clinical trials |
| Roselle | Hyperlipidemia | 1 | PM | 28049927 | 📋 | Hypolipidemic and Hypocholesterolemic Effect of Roselle (Hibiscus Sabdariffa L.) Seeds Oil in Experimental Male Rats |
| Roselle | Hyperlipidemia | 2 | PM | 20369795 | 📋 | Hypolipidemic Effect of Ethanolic Extract From the Leaves of Hibiscus Sabdariffa L. In Hyperlipidemic Rats |
| Roselle | Hyperlipidemia | 3 | PM | 18034661 | 📋 | Hypolipidemic and Antioxidant Effects of Ethanolic Extract From Dried Calyx of Hibiscus Sabdariffa in Alloxan-Induced Diabetic Rats |
| Roselle | Hypertriglyceridemia | 1 | PM | 26982618 | 📋 | Evaluation of the Effects of Roselle (Hibiscus Sabdariffa L.) on Oxidative Stress and Serum Levels of Lipids, Insulin and hs-CRP in Adult Patients With Metabolic Syndrome: A Double-Blind Placebo-Controlled Clinical Trial |
| Roselle | Insulin Resistance | 5 | PM | 36554419 | 📋 | Serum Phospholipids Are Potential Therapeutic Targets of Aqueous Extracts of Roselle ( Hibiscus sabdariffa) against Obesity and Insulin Resistance |
| Roselle | Insulin Resistance | 4 | PM | 35487948 | 📋 | Hibiscus sabdariffa extract improves hepatic steatosis, partially through IRS-1/Akt and Nrf2 signaling pathways in rats fed a high fat diet |
| Roselle | Insulin Resistance | 3 | PM | 33721756 | 📋 | Hibiscus sabdariffa L. calyx extract prevents the adipogenesis of 3T3-L1 adipocytes, and obesity-related insulin resistance in high-fat diet-induced obese rats |
| Roselle | Insulin Resistance | 1 | PM | 25965053 | 📋 | Hibiscus Sabdariffa Calyx Palliates Insulin Resistance, Hyperglycemia, Dyslipidemia and Oxidative Rout in Fructose-Induced Metabolic Syndrome Rats |
| Roselle | Insulin Resistance | 2 | PM | 25226384 | 📋 | Hibiscus Sabdariffa Polyphenols Alleviate Insulin Resistance and Renal Epithelial to Mesenchymal Transition: A Novel Action Mechanism Mediated by Type 4 Dipeptidyl Peptidase |
| Roselle | Iron Overload | 1 | PM | 35159249 | 📋 | A Distinct Hibiscus sabdariffa Extract Prevents Iron Neurotoxicity, a Driver of Multiple Sclerosis Pathology |
| Roselle | Metabolic Syndrome | 8 | PM | 37762512 | 📋 | Effect of Hibiscus sabdariffa L. on the Metabolism of Arachidonic Acid in the Isolated Kidney of a Rat Model of Metabolic Syndrome |
| Roselle | Metabolic Syndrome | 7 | PM | 37297513 | 📋 | Effect of the Combination of Hibiscus sabdariffa in Combination with Other Plant Extracts in the Prevention of Metabolic Syndrome: A Systematic Review and Meta-Analysis |
| Roselle | Metabolic Syndrome | 6 | PM | 33916540 | 📋 | Modulation of Renal Function in a Metabolic Syndrome Rat Model by Antioxidants in Hibiscus sabdariffa L |
| Roselle | Metabolic Syndrome | 2 | PM | 33005201 | 📋 | Action Mechanism of Rosella ( Hibiscus sabdariffa L.) Used to Treat Metabolic Syndrome in Elderly Women |
| Roselle | Metabolic Syndrome | 3 | PM | 31882094 | 📋 | The Prebiotic Properties of Hibiscus Sabdariffa Extract Contribute to the Beneficial Effects in Diet-Induced Obesity in Mice |
| Roselle | Metabolic Syndrome | 4 | PM | 31833112 | 📋 | Effect of Hibiscus Sabdariffa (Roselle) Supplementation in Regulating Blood Lipids Among Patients With Metabolic Syndrome and Related Disorders: A Systematic Review and Meta-Analysis |
| Roselle | Metabolic Syndrome | 1 | PM | 26982618 | 📋 | Evaluation of the Effects of Roselle (Hibiscus Sabdariffa L.) on Oxidative Stress and Serum Levels of Lipids, Insulin and hs-CRP in Adult Patients With Metabolic Syndrome: A Double-Blind Placebo-Controlled Clinical Trial |
| Roselle | Metabolic Syndrome | 5 | PM | 25965053 | 📋 | Hibiscus Sabdariffa Calyx Palliates Insulin Resistance, Hyperglycemia, Dyslipidemia and Oxidative Rout in Fructose-Induced Metabolic Syndrome Rats |
| Roselle | Obesity | 11 | PM | 37714233 | 📋 | Chemical profile of Roselle extract and its inhibitory activities on three digestive enzymes in vitro and in vivo |
| Roselle | Obesity | 10 | PM | 37608673 | 📋 | Hibiscus sabdariffa Linn. Extract Increases the mRNA Expression of the Arcuate Nucleus Leptin Receptor and is Predicted in silico as an Anti-obesity Agent |
| Roselle | Obesity | 9 | PM | 36554419 | 📋 | Serum Phospholipids Are Potential Therapeutic Targets of Aqueous Extracts of Roselle ( Hibiscus sabdariffa) against Obesity and Insulin Resistance |
| Roselle | Obesity | 1 | PM | 35166751 | 📋 | Phytochemistry profile of rosella and jambolan extracts and the therapeutic effects on obesity |
| Roselle | Obesity | 8 | PM | 34687158 | 📋 | Potential of Hibiscus sabdariffa Linn. in managing FGF21 resistance in diet-induced-obesity rats via miR-34a regulation |
| Roselle | Obesity | 7 | PM | 34591168 | 📋 | Effectiveness of a polyphenolic extract (Lippia citriodora and Hibiscus sabdariffa) on appetite regulation in overweight and obese grade I population: an 8-week randomized, double-blind, cross-over, placebo-controlled trial |
| Roselle | Obesity | 6 | PM | 33721756 | 📋 | Hibiscus sabdariffa L. calyx extract prevents the adipogenesis of 3T3-L1 adipocytes, and obesity-related insulin resistance in high-fat diet-induced obese rats |
| Roselle | Obesity | 2 | PM | 30626104 | 📋 | Beneficial Effects of Natural Bioactive Compounds From Hibiscus sabdariffa L. On Obesity |
| Roselle | Obesity | 3 | PM | 30200432 | 📋 | Metabolaid ® Combination of Lemon Verbena and Hibiscus Flower Extract Prevents High-Fat Diet-Induced Obesity Through AMP-Activated Protein Kinase Activation |
| Roselle | Obesity | 4 | PM | 28825642 | 📋 | Multi-Targeted Molecular Effects of Hibiscus Sabdariffa Polyphenols: An Opportunity for a Global Approach to Obesity |
| Roselle | Obesity | 5 | PM | 24549255 | 📋 | Hibiscus Sabdariffa Extract Inhibits Obesity and Fat Accumulation, and Improves Liver Steatosis in Humans |
| Roselle | Overweight | 1 | PM | 34591168 | 📋 | Effectiveness of a polyphenolic extract (Lippia citriodora and Hibiscus sabdariffa) on appetite regulation in overweight and obese grade I population: an 8-week randomized, double-blind, cross-over, placebo-controlled trial |
| Roselle | Overweight | 2 | PM | 29862395 | 📋 | Hibiscus and lemon verbena polyphenols modulate appetite-related biomarkers in overweight subjects: a randomized controlled trial |
