| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| NMN | Diabetes Type 2 | 2 | PM | 38473844 | 📋 | Nicotinamide Mononucleotide (NMN) Works in Type 2 Diabetes through Unexpected Effects in Adipose Tissue, Not by Mitochondrial Biogenesis |
| NMN | Diabetes Type 2 | 1 | PM | 21982712 | 📋 | Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice |
| NMN | Glucose Metabolism Disorder | 2 | PM | 35218657 | 📋 | Intestinal epithelial NAD + biosynthesis regulates GLP-1 production and postprandial glucose metabolism in mice |
| NMN | Glucose Metabolism Disorder | 1 | PM | 35123833 | 📋 | Nicotinamide mononucleotide promotes pancreatic islet function through the SIRT1 pathway in mice after severe burns |
| NMN | Glucose Metabolism Disorder | 3 | PM | 28435063 | 📋 | Regulation of Nampt expression by transcriptional coactivator NCOA6 in pancreatic β-cells |
| NMN | Hypercholesterolemia | 1 | PM | 36740954 | 📋 | Nicotinamide Adenine Dinucleotide Augmentation in Overweight or Obese Middle-Aged and Older Adults: A Physiologic Study |
| NMN | Hypertriglyceridemia | 1 | PM | 36225528 | 📋 | Nicotinamide Mononucleotide Is Safely Metabolized and Significantly Reduces Blood Triglyceride Levels in Healthy Individuals |
| NMN | Insulin Resistance | 5 | PM | 38703507 | 📋 | Alleviation of hepatic insulin resistance and steatosis with NMN via improving endoplasmic reticulum-Mitochondria miscommunication in the liver of HFD mice |
| NMN | Insulin Resistance | 3 | PM | 34948019 | 📋 | Nicotinamide Mononucleotide Prevents Free Fatty Acid-Induced Reduction in Glucose Tolerance by Decreasing Insulin Clearance |
| NMN | Insulin Resistance | 1 | PM | 33888596 | 📋 | Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women |
| NMN | Insulin Resistance | 2 | PM | 32087266 | 📋 | Resveratrol protects against ethanol-induced impairment of insulin secretion in INS-1 cells through SIRT1-UCP2 axis |
| NMN | Insulin Resistance | 4 | PM | 27498863 | 📋 | NAMPT-Mediated NAD(+) Biosynthesis in Adipocytes Regulates Adipose Tissue Function and Multi-organ Insulin Sensitivity in Mice |
| NMN | Lactic Acidosis | 1 | PM | 30816177 | 📋 | Targeting NAD + Metabolism as Interventions for Mitochondrial Disease |
| NMN | Metabolic Disorders | 7 | PM | 38473844 | 📋 | Nicotinamide Mononucleotide (NMN) Works in Type 2 Diabetes through Unexpected Effects in Adipose Tissue, Not by Mitochondrial Biogenesis |
| NMN | Metabolic Disorders | 4 | PM | 36785893 | 📋 | Nicotinamide mononucleotide alters body composition and ameliorates metabolic disorders induced by a high-fat diet |
| NMN | Metabolic Disorders | 3 | PM | 35218657 | 📋 | Intestinal epithelial NAD + biosynthesis regulates GLP-1 production and postprandial glucose metabolism in mice |
| NMN | Metabolic Disorders | 2 | PM | 35173682 | 📋 | NAD+-Increasing Strategies to Improve Cardiometabolic Health? |
| NMN | Metabolic Disorders | 1 | PM | 32218167 | 📋 | Administration of Nicotinamide Mononucleotide (NMN) Reduces Metabolic Impairment in Male Mouse Offspring From Obese Mothers |
| NMN | Metabolic Disorders | 6 | PM | 29118320 | 📋 | Nicotinamide mononucleotide (NMN) supplementation ameliorates the impact of maternal obesity in mice: comparison with exercise |
| NMN | Metabolic Disorders | 5 | PM | 27498863 | 📋 | NAMPT-Mediated NAD(+) Biosynthesis in Adipocytes Regulates Adipose Tissue Function and Multi-organ Insulin Sensitivity in Mice |
| NMN | Mitochondrial Dysfunction | 4 | PM | 36499074 | 📋 | Nicotinamide Mononucleotide Supplementation Improves Mitochondrial Dysfunction and Rescues Cellular Senescence by NAD+/Sirt3 Pathway in Mesenchymal Stem Cells |
| NMN | Mitochondrial Dysfunction | 8 | PM | 35051613 | 📋 | NAD supplementation improves mitochondrial performance of cardiolipin mutants |
| NMN | Mitochondrial Dysfunction | 7 | PM | 34865026 | 📋 | Mitochondria metabolomics reveals a role of β-nicotinamide mononucleotide metabolism in mitochondrial DNA replication |
| NMN | Mitochondrial Dysfunction | 3 | PM | 32056076 | 📋 | Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects |
| NMN | Mitochondrial Dysfunction | 2 | PM | 31678348 | 📋 | Nicotinamide Mononucleotide and Melatonin Alleviate Aging-induced Cognitive Impairment via Modulation of Mitochondrial Function and Apoptosis in the Prefrontal Cortex and Hippocampus |
| NMN | Mitochondrial Dysfunction | 1 | PM | 30801823 | 📋 | Nicotinamide mononucleotide alters mitochondrial dynamics by SIRT3-dependent mechanism in male mice |
| NMN | Mitochondrial Dysfunction | 6 | PM | 28882480 | 📋 | Short-term administration of Nicotinamide Mononucleotide preserves cardiac mitochondrial homeostasis and prevents heart failure |
| NMN | Mitochondrial Dysfunction | 5 | PM | 25884176 | 📋 | Effect of nicotinamide mononucleotide on brain mitochondrial respiratory deficits in an Alzheimer's disease-relevant murine model |
| NMN | Mitochondrial Myopathy | 1 | PM | 30816177 | 📋 | Targeting NAD + Metabolism as Interventions for Mitochondrial Disease |
| NMN | Obesity | 4 | PM | 37144119 | 📋 | Nicotinamide mononucleotide induces lipolysis by regulating ATGL expression via the SIRT1-AMPK axis in adipocytes |
| NMN | Obesity | 3 | PM | 36785893 | 📋 | Nicotinamide mononucleotide alters body composition and ameliorates metabolic disorders induced by a high-fat diet |
| NMN | Obesity | 2 | PM | 31226694 | 📋 | Impacts of obesity, maternal obesity and nicotinamide mononucleotide supplementation on sperm quality in mice |
| NMN | Obesity | 1 | PM | 30895251 | 📋 | Multigenerational obesity-induced perturbations in oocyte-secreted factor signalling can be ameliorated by exercise and nicotinamide mononucleotide |
| NMN | Postprandial Hyperglycemia | 1 | PM | 35218657 | 📋 | Intestinal epithelial NAD + biosynthesis regulates GLP-1 production and postprandial glucose metabolism in mice |
