| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| N-Acetyl Cysteine | AGE Products | 1 | PM | 27315604 | 📋 | Advanced Glycation End Products Inhibit Testosterone Secretion by Rat Leydig Cells by Inducing Oxidative Stress and Endoplasmic Reticulum Stress |
| N-Acetyl Cysteine | Diabetes Type 2 | 4 | PM | 38397782 | 📋 | The Role of Glutathione and Its Precursors in Type 2 Diabetes |
| N-Acetyl Cysteine | Diabetes Type 2 | 3 | PM | 36093092 | 📋 | N-acetyl-L-cysteine treatment reduces beta-cell oxidative stress and pancreatic stellate cell activity in a high fat diet-induced diabetic mouse model |
| N-Acetyl Cysteine | Diabetes Type 2 | 2 | PM | 35052658 | 📋 | GlyNAC (Glycine and N-Acetylcysteine) Supplementation Improves Impaired Mitochondrial Fuel Oxidation and Lowers Insulin Resistance in Patients with Type 2 Diabetes: Results of a Pilot Study |
| N-Acetyl Cysteine | Diabetes Type 2 | 1 | PM | 18268065 | 📋 | Long-term N-acetylcysteine and L-arginine Administration Reduces Endothelial Activation and Systolic Blood Pressure in Hypertensive Patients With Type 2 Diabetes |
| N-Acetyl Cysteine | Insulin Resistance | 5 | PM | 37794966 | 📋 | Effects of N-acetylcysteine on aging cell and obesity complications in obese adults: a randomized, double-blind clinical trial |
| N-Acetyl Cysteine | Insulin Resistance | 4 | PM | 35052658 | 📋 | GlyNAC (Glycine and N-Acetylcysteine) Supplementation Improves Impaired Mitochondrial Fuel Oxidation and Lowers Insulin Resistance in Patients with Type 2 Diabetes: Results of a Pilot Study |
| N-Acetyl Cysteine | Insulin Resistance | 3 | PM | 34684414 | 📋 | Antioxidants Supplementation Reduces Ceramide Synthesis Improving the Cardiac Insulin Transduction Pathway in a Rodent Model of Obesity |
| N-Acetyl Cysteine | Insulin Resistance | 2 | PM | 34505526 | 📋 | High cysteine diet reduces insulin resistance in SHR-CRP Rats |
| N-Acetyl Cysteine | Insulin Resistance | 1 | PM | 33783984 | 📋 | Glycine and N-acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, genotoxicity, muscle strength, and cognition: Results of a pilot clinical trial |
| N-Acetyl Cysteine | Iron Overload | 3 | PM | 38396357 | 📋 | Acetylated oligopeptide and N-acetylcysteine protect against iron overload-induced dentate gyrus hippocampal degeneration through upregulation of Nestin and Nrf2/HO-1 and downregulation of MMP-9/TIMP-1 and GFAP |
| N-Acetyl Cysteine | Iron Overload | 2 | PM | 36947366 | 📋 | Acetylated Oligopeptide and N-acetyl cysteine Protected Against Oxidative Stress, Inflammation, Testicular-Blood Barrier Damage, and Testicular Cell Death in Iron-Overload Rat Model |
| N-Acetyl Cysteine | Iron Overload | 1 | PM | 33147909 | 📋 | Randomized controlled trial of effect of N-acetylcysteine as an antioxidant on iron overload in children with thalassemia major |
| N-Acetyl Cysteine | Metabolic Disorders | 1 | PM | 32444367 | 📋 | Antioxidant Effects of N-Acetylcysteine Prevent Programmed Metabolic Disease in Mice |
| N-Acetyl Cysteine | Metabolic Syndrome | 2 | PM | 33507837 | 📋 | N-acetyl cysteine can blunt metabolic and cardiovascular effects via down-regulation of cardiotrophin-1 in rat model of fructose-induced metabolic syndrome |
| N-Acetyl Cysteine | Metabolic Syndrome | 1 | PM | 32552298 | 📋 | Effect of N-Acetylcysteine on Metabolic Profile in Metabolic Syndrome Patients |
| N-Acetyl Cysteine | Mitochondrial Dysfunction | 2 | PM | 37419232 | 📋 | N-acetylcysteine modulates rotenone-induced mitochondrial Complex I dysfunction in THP-1 cells |
| N-Acetyl Cysteine | Mitochondrial Dysfunction | 4 | PM | 35403558 | 📋 | N-acetylcysteine ameliorates monocrotophos exposure-induced mitochondrial dysfunctions in rat liver |
| N-Acetyl Cysteine | Mitochondrial Dysfunction | 3 | PM | 35052658 | 📋 | GlyNAC (Glycine and N-Acetylcysteine) Supplementation Improves Impaired Mitochondrial Fuel Oxidation and Lowers Insulin Resistance in Patients with Type 2 Diabetes: Results of a Pilot Study |
| N-Acetyl Cysteine | Mitochondrial Dysfunction | 1 | PM | 33640978 | 📋 | Combinatorial glucose, nicotinic acid, and N-acetylcysteine therapy has synergistic effect in preclinical C. elegans and zebrafish models of mitochondrial complex I disease |
| N-Acetyl Cysteine | Obesity | 6 | PM | 37794966 | 📋 | Effects of N-acetylcysteine on aging cell and obesity complications in obese adults: a randomized, double-blind clinical trial |
| N-Acetyl Cysteine | Obesity | 5 | PM | 33191885 | 📋 | Legacy Effect of Antioxidant N-acetylcysteine in Cellular Senescence of Diet-induced Obesity Mice |
| N-Acetyl Cysteine | Obesity | 4 | PM | 32676884 | 📋 | A combination of an antioxidant with a prebiotic exerts greater efficacy than either as a monotherapy on cognitive improvement in castrated-obese male rats |
| N-Acetyl Cysteine | Obesity | 3 | PM | 32378169 | 📋 | Correlation Between Oxidative Stress and NF-κB Signaling Pathway in the Obesity-Asthma Mice |
| N-Acetyl Cysteine | Obesity | 1 | PM | 32215468 | 📋 | Reduction of Oxidative Stress Improves Insulin Signaling in Cardiac Tissue of Obese Mice |
| N-Acetyl Cysteine | Obesity | 2 | PM | 31838118 | 📋 | Redox Status, Inflammation, Necroptosis and Inflammasome as Indispensable Contributors to High Fat Diet (HFD)-induced Neurodegeneration; Effect of N-acetylcysteine (NAC) |
