| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Astaxanthin | AGE Products | 1 | PM | 21779563 | 📋 | Protective Actions of Microalgae Against Endogenous and Exogenous Advanced Glycation Endproducts (AGEs) in Human Retinal Pigment Epithelial Cells |
| Astaxanthin | Diabetes Type 2 | 3 | PM | 37534224 | 📋 | Astaxanthin improves fatty acid dysregulation in diabetes by controlling the AMPK-SIRT1 pathway |
| Astaxanthin | Diabetes Type 2 | 8 | PM | 33445213 | 📋 | The antioxidant and anti-inflammatory effects of astaxanthin supplementation on the expression of miR-146a and miR-126 in patients with type 2 diabetes mellitus: A randomized, double-blind, placebo-controlled clinical trial |
| Astaxanthin | Diabetes Type 2 | 2 | PM | 33268598 | 📋 | Anti-diabetic effects of astaxanthin on an STZ-induced diabetic model in rats |
| Astaxanthin | Diabetes Type 2 | 1 | PM | 29384321 | 📋 | Astaxanthin Improves Glucose Metabolism and Reduces Blood Pressure in Patients With Type 2 Diabetes Mellitus |
| Astaxanthin | Diabetes Type 2 | 5 | PM | 12688512 | 📋 | Astaxanthin Protects Beta-Cells Against Glucose Toxicity in Diabetic Db/Db Mice |
| Astaxanthin | Glucose Metabolism Disorder | 2 | PM | 34959932 | 📋 | The Beneficial Effects of Astaxanthin on Glucose Metabolism and Modified Low-Density Lipoprotein in Healthy Volunteers and Subjects with Prediabetes |
| Astaxanthin | Glucose Metabolism Disorder | 1 | PM | 31811643 | 📋 | Astaxanthin Encapsulated in Biodegradable Calcium Alginate Microspheres for the Treatment of Hepatocellular Carcinoma In Vitro |
| Astaxanthin | Hypercholesterolemia | 6 | PM | 37051124 | 📋 | Effects of Astaxanthin supplementation on selected metabolic parameters, anthropometric indices, Sirtuin1 and TNF-α levels in patients with coronary artery disease: A randomized, double-blind, placebo-controlled clinical trial |
| Astaxanthin | Hypercholesterolemia | 5 | PM | 36999233 | 📋 | Astaxanthin, a Natural Antioxidant, Lowers Cholesterol and Markers of Cardiovascular Risk in Individuals with Prediabetes and Dyslipidemia |
| Astaxanthin | Hypercholesterolemia | 2 | PM | 30723735 | 📋 | Effects of a New Combination of Medical Food on Endothelial Function and Lipid Profile in Dyslipidemic Subjects: A Pilot Randomized Trial |
| Astaxanthin | Hypercholesterolemia | 7 | PM | 27998714 | 📋 | A nutraceutical approach (Armolipid Plus) to reduce total and LDL cholesterol in individuals with mild to moderate dyslipidemia: Review of the clinical evidence |
| Astaxanthin | Hypercholesterolemia | 4 | PM | 25870124 | 📋 | Effects of a new combination of nutraceuticals with Morus alba on lipid profile, insulin sensitivity and endotelial function in dyslipidemic subjects. A cross-over, randomized, double-blind trial |
| Astaxanthin | Hypercholesterolemia | 3 | PM | 25084280 | 📋 | Effects of poly-bioactive compounds on lipid profile and body weight in a moderately hypercholesterolemic population with low cardiovascular disease risk: a multicenter randomized trial |
| Astaxanthin | Hypercholesterolemia | 8 | PM | 22113535 | 📋 | Long-term effects of nutraceuticals (berberine, red yeast rice, policosanol) in elderly hypercholesterolemic patients |
| Astaxanthin | Hypercholesterolemia | 1 | PM | 21964877 | 📋 | Positive Effects of Astaxanthin on Lipid Profiles and Oxidative Stress in Overweight Subjects |
| Astaxanthin | Hyperlipidemia | 2 | PM | 34375188 | 📋 | Astaxanthin Attenuates Adiponectin, Calprotectin, miRNA222 and miRNA378 in Obesity induced by High-Fat Diet in Rats |
| Astaxanthin | Hyperlipidemia | 1 | PM | 32379559 | 📋 | Antiplatelet Activity of Astaxanthin in Control- And High Cholesterol-Fed Rats Mediated by Down-Regulation of P2Y 12, Inhibition of NF-κB, and Increasing Intracellular Levels of cAMP |
| Astaxanthin | Hyperlipidemia | 4 | PM | 28539740 | 📋 | Evaluation of Antioxidant, Hypolipidemic, and Antiatherogenic Property of Lycopene and Astaxanthin in Atherosclerosis-induced Rats |
| Astaxanthin | Hyperlipidemia | 3 | PM | 26611120 | 📋 | Usefulness of Nutraceuticals (Armolipid Plus) Versus Ezetimibe and Combination in Statin-Intolerant Patients With Dyslipidemia With Coronary Heart Disease |
| Astaxanthin | Insulin Resistance | 10 | PM | 34959932 | 📋 | The Beneficial Effects of Astaxanthin on Glucose Metabolism and Modified Low-Density Lipoprotein in Healthy Volunteers and Subjects with Prediabetes |
| Astaxanthin | Insulin Resistance | 9 | PM | 34375188 | 📋 | Astaxanthin Attenuates Adiponectin, Calprotectin, miRNA222 and miRNA378 in Obesity induced by High-Fat Diet in Rats |
| Astaxanthin | Insulin Resistance | 8 | PM | 32998286 | 📋 | Astaxanthin Inhibits p70 S6 Kinase 1 Activity to Sensitize Insulin Signaling |
| Astaxanthin | Insulin Resistance | 7 | PM | 32501299 | 📋 | Effects of Astaxanthin on Inflammation and Insulin Resistance in a Mouse Model of Gestational Diabetes Mellitus |
| Astaxanthin | Insulin Resistance | 1 | PM | 32245087 | 📋 | Astaxanthin n-Octanoic Acid Diester Ameliorates Insulin Resistance and Modulates Gut Microbiota in High-Fat and High-Sucrose Diet-Fed Mice |
| Astaxanthin | Insulin Resistance | 5 | PM | 32003547 | 📋 | Astaxanthin Stimulates Mitochondrial Biogenesis in Insulin Resistant Muscle via Activation of AMPK Pathway |
| Astaxanthin | Insulin Resistance | 2 | PM | 26603489 | 📋 | Astaxanthin Prevents and Reverses Diet-Induced Insulin Resistance and Steatohepatitis in Mice: A Comparison With Vitamin E |
| Astaxanthin | Insulin Resistance | 11 | PM | 23715867 | 📋 | Impact of divergent effects of astaxanthin on insulin signaling in L6 cells |
| Astaxanthin | Insulin Resistance | 4 | PM | 23181282 | 📋 | Astaxanthin Prevents Loss of Insulin Signaling and Improves Glucose Metabolism in Liver of Insulin Resistant Mice |
| Astaxanthin | Insulin Resistance | 3 | PM | 22089895 | 📋 | An Intervention Study in Obese Mice With Astaxanthin, a Marine Carotenoid--Effects on Insulin Signaling and Pro-Inflammatory Cytokines |
| Astaxanthin | Insulin Resistance | 6 | PM | 21326955 | 📋 | High Dose Astaxanthin Lowers Blood Pressure and Increases Insulin Sensitivity in Rats: Are These Effects Interdependent? |
| Astaxanthin | Iron Overload | 1 | PM | 11594777 | 📋 | Astaxanthin and Peridinin Inhibit Oxidative Damage in Fe(2+)-loaded Liposomes: Scavenging Oxyradicals or Changing Membrane Permeability? |
| Astaxanthin | Metabolic Disorders | 6 | PM | 38004197 | 📋 | Astaxanthin Supplementation Augments the Benefits of CrossFit Workouts on Semaphorin 3C and Other Adipokines in Males with Obesity |
| Astaxanthin | Metabolic Disorders | 5 | PM | 37114194 | 📋 | Astaxanthin Reduces Heart Rate and Carbohydrate Oxidation Rates During Exercise in Overweight Individuals |
| Astaxanthin | Metabolic Disorders | 4 | PM | 36678157 | 📋 | Astaxanthin Supplemented with High-Intensity Functional Training Decreases Adipokines Levels and Cardiovascular Risk Factors in Men with Obesity |
| Astaxanthin | Metabolic Disorders | 3 | PM | 36354983 | 📋 | Astaxanthin Exerts Immunomodulatory Effect by Regulating SDH-HIF-1α Axis and Reprogramming Mitochondrial Metabolism in LPS-Stimulated RAW264.7 Cells |
| Astaxanthin | Metabolic Disorders | 2 | PM | 35055102 | 📋 | Astaxanthin Exerts Anabolic Effects via Pleiotropic Modulation of the Excitable Tissue |
| Astaxanthin | Metabolic Disorders | 1 | PM | 35035906 | 📋 | Mechanistic role of astaxanthin derived from shrimp against certain metabolic disorders |
| Astaxanthin | Metabolic Syndrome | 2 | PM | 35631193 | 📋 | Astaxanthin Influence on Health Outcomes of Adults at Risk of Metabolic Syndrome: A Systematic Review and Meta-Analysis |
| Astaxanthin | Metabolic Syndrome | 1 | PM | 17074368 | 📋 | Astaxanthin Ameliorates Features of Metabolic Syndrome in SHR/NDmcr-cp |
| Astaxanthin | Mitochondrial Dysfunction | 11 | PM | 38393028 | 📋 | Astaxanthin Inhibits H2O2-Induced Excessive Mitophagy and Apoptosis in SH-SY5Y Cells by Regulation of Akt/mTOR Activation |
| Astaxanthin | Mitochondrial Dysfunction | 10 | PM | 35010981 | 📋 | Astaxanthin as a Novel Mitochondrial Regulator: A New Aspect of Carotenoids, beyond Antioxidants |
| Astaxanthin | Mitochondrial Dysfunction | 9 | PM | 34801514 | 📋 | Protective effects of dietary curcumin and astaxanthin against heat-induced ROS production and skeletal muscle injury in male and female C57BL/6J mice |
| Astaxanthin | Mitochondrial Dysfunction | 8 | PM | 34265290 | 📋 | Astaxanthin prevents mitochondrial impairment in the dopaminergic SH-SY5Y cell line exposed to glutamate-mediated excitotoxicity: Role for the Nrf2/HO-1/CO-BR axis |
| Astaxanthin | Mitochondrial Dysfunction | 7 | PM | 33775716 | 📋 | The signaling pathway PI3K/Akt/Nrf2/HO-1 plays a role in the mitochondrial protection promoted by astaxanthin in the SH-SY5Y cells exposed to hydrogen peroxide |
| Astaxanthin | Mitochondrial Dysfunction | 6 | PM | 33092172 | 📋 | Isoproterenol-Induced Permeability Transition Pore-Related Dysfunction of Heart Mitochondria Is Attenuated by Astaxanthin |
| Astaxanthin | Mitochondrial Dysfunction | 5 | PM | 32446270 | 📋 | Astaxanthin Attenuates Hepatic Damages and Mitochondrial Dysfunction in Nonalcoholic Fatty Liver Disease by Up-Regulating the FGF21/PGC-1α Pathway |
| Astaxanthin | Mitochondrial Dysfunction | 2 | PM | 30231525 | 📋 | Astaxanthin Inhibits Mitochondrial Dysfunction and Interleukin-8 Expression in Helicobacter pylori-Infected Gastric Epithelial Cells |
| Astaxanthin | Mitochondrial Dysfunction | 4 | PM | 30134611 | 📋 | Inhibitory Effect of Astaxanthin on Oxidative Stress-Induced Mitochondrial Dysfunction-A Mini-Review |
| Astaxanthin | Mitochondrial Dysfunction | 1 | PM | 23100599 | 📋 | Astaxanthin Modulates Age-Associated Mitochondrial Dysfunction in Healthy Dogs |
| Astaxanthin | Mitochondrial Dysfunction | 3 | PM | 19423317 | 📋 | Astaxanthin Protects Mitochondrial Redox State and Functional Integrity Against Oxidative Stress |
| Astaxanthin | Obesity | 11 | PM | 37490309 | 📋 | Astaxanthin reduces fat storage in a fat-6/ fat-7 dependent manner determined using high fat Caenorhabditis elegans |
| Astaxanthin | Obesity | 10 | PM | 36352906 | 📋 | A protein- and fiber-rich diet with astaxanthin alleviates high-fat diet-induced obesity in beagles |
| Astaxanthin | Obesity | 9 | PM | 34664590 | 📋 | Astaxanthin from Haematococcus pluvialis alleviates obesity by modulating lipid metabolism and gut microbiota in mice fed a high-fat diet |
| Astaxanthin | Obesity | 8 | PM | 34552567 | 📋 | Microbial Composition and Co-occurrence Patterns in the Gut Microbial Community of Normal and Obese Mice in Response to Astaxanthin |
| Astaxanthin | Obesity | 7 | PM | 34375188 | 📋 | Astaxanthin Attenuates Adiponectin, Calprotectin, miRNA222 and miRNA378 in Obesity induced by High-Fat Diet in Rats |
| Astaxanthin | Obesity | 6 | PM | 33974978 | 📋 | Effects of astaxanthin in animal models of obesity-associated diseases: a systematic review and meta-analysis |
| Astaxanthin | Obesity | 5 | PM | 32784687 | 📋 | Effect of Astaxanthin on the Inhibition of Lipid Accumulation in 3T3-L1 Adipocytes via Modulation of Lipogenesis and Fatty Acid Transport Pathways |
| Astaxanthin | Obesity | 4 | PM | 30859086 | 📋 | Effects of Astaxanthin Supplementation in Healthy and Obese Dogs |
| Astaxanthin | Obesity | 3 | PM | 26147624 | 📋 | Preventive Effects of Astaxanthin on Diethylnitrosamine-Induced Liver Tumorigenesis in C57/BL/KsJ-db/db Obese Mice |
| Astaxanthin | Obesity | 1 | PM | 21964877 | 📋 | Positive Effects of Astaxanthin on Lipid Profiles and Oxidative Stress in Overweight Subjects |
| Astaxanthin | Obesity | 2 | PM | 21480416 | 📋 | Effects of Astaxanthin on Oxidative Stress in Overweight and Obese Adults |
| Astaxanthin | Overweight | 2 | PM | 36352906 | 📋 | A protein- and fiber-rich diet with astaxanthin alleviates high-fat diet-induced obesity in beagles |
| Astaxanthin | Overweight | 1 | PM | 21964877 | 📋 | Positive Effects of Astaxanthin on Lipid Profiles and Oxidative Stress in Overweight Subjects |
| Astaxanthin | Prediabetes | 1 | PM | 34959932 | 📋 | The Beneficial Effects of Astaxanthin on Glucose Metabolism and Modified Low-Density Lipoprotein in Healthy Volunteers and Subjects with Prediabetes |
