| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Apple | AGE Products | 2 | PM | 20022617 | 📋 | Dihydrochalcones: Implication in resistance to oxidative stress and bioactivities against advanced glycation end-products and vasoconstriction |
| Apple | Diabetes Type 2 | 2 | PM | 31302831 | 📋 | Apple Phenolic Extracts Strongly Inhibit α-Glucosidase Activity |
| Apple | Diabetes Type 2 | 1 | PM | 28186516 | 📋 | Apple and pear consumption and type 2 diabetes mellitus risk: a meta-analysis of prospective cohort studies |
| Apple | Excessive Weight | 1 | PM | 29630462 | 📋 | Weight Loss Associated With Consumption of Apples: A Review |
| Apple | Hypercholesterolemia | 3 | PM | 35449537 | 📋 | Metabolic and Cardiovascular Benefits of Apple and Apple-Derived Products: A Systematic Review and Meta-Analysis of Randomized Controlled Trials |
| Apple | Hypercholesterolemia | 4 | PM | 33917635 | 📋 | Beneficial Metabolic Effect of a Nutraceuticals Combination (Monacolin K, Yeasted Red Rice, Polyphenolic Extract of Annurca Apple and Berberine) on Acquired Hypercholesterolemia: A Prospective Analysis |
| Apple | Hypercholesterolemia | 1 | PM | 31840162 | 📋 | Two apples a day lower serum cholesterol and improve cardiometabolic biomarkers in mildly hypercholesterolemic adults: a randomized, controlled, crossover trial |
| Apple | Hypercholesterolemia | 2 | PM | 31763011 | 📋 | Characterization of juice fermented with Lactobacillus plantarum EM and its cholesterol-lowering effects on rats fed a high-fat and high-cholesterol diet |
| Apple | Hyperglycemia | 4 | PM | 33802755 | 📋 | Cloudy Apple Juice Fermented by Lactobacillus Prevents Obesity via Modulating Gut Microbiota and Protecting Intestinal Tract Health |
| Apple | Hyperglycemia | 2 | PM | 32326848 | 📋 | Inhibitory effects of bioaccessible anthocyanins and procyanidins from apple, red grape, cinnamon on α-amylase, α-glucosidase and lipase |
| Apple | Hyperglycemia | 1 | PM | 31302831 | 📋 | Apple Phenolic Extracts Strongly Inhibit α-Glucosidase Activity |
| Apple | Hyperglycemia | 3 | PM | 20874247 | 📋 | Varietal influences on antihyperglycemia properties of freshly harvested apples using in vitro assay models |
| Apple | Hyperlipidemia | 1 | PM | 33102196 | 📋 | Antihyperlipidemic effects of apple peel extract in high-fat diet-induced hyperlipidemic rats |
| Apple | Hyperlipidemia | 2 | PM | 12952433 | 📋 | Apple and pear peel and pulp and their influence on plasma lipids and antioxidant potentials in rats fed cholesterol-containing diets |
| Apple | Hypertriglyceridemia | 1 | PM | 33917635 | 📋 | Beneficial Metabolic Effect of a Nutraceuticals Combination (Monacolin K, Yeasted Red Rice, Polyphenolic Extract of Annurca Apple and Berberine) on Acquired Hypercholesterolemia: A Prospective Analysis |
| Apple | Metabolic Disorders | 1 | PM | 36290676 | 📋 | Onion and Apple Functional Ingredients Intake Improves Antioxidant and Inflammatory Status and Vascular Injury in Obese Zucker Rats |
| Apple | Metabolic Syndrome | 1 | PM | 36983908 | 📋 | Apple Peel Supplementation Potential in Metabolic Syndrome Prevention |
| Apple | Obesity | 4 | PM | 35205973 | 📋 | Effect of Anti-Obesity and Antioxidant Activity through the Additional Consumption of Peel from 'Fuji' Pre-Washed Apple |
| Apple | Obesity | 8 | PM | 33964852 | 📋 | Daily apple consumption reduces plasma and peripheral blood mononuclear cell-secreted inflammatory biomarkers in adults with overweight and obesity: a 6-week randomized, controlled, parallel-arm trial |
| Apple | Obesity | 7 | PM | 33802755 | 📋 | Cloudy Apple Juice Fermented by Lactobacillus Prevents Obesity via Modulating Gut Microbiota and Protecting Intestinal Tract Health |
| Apple | Obesity | 2 | PM | 31312904 | 📋 | Modified apple polysaccharide regulates microbial dysbiosis to suppress high-fat diet-induced obesity in C57BL/6J mice |
| Apple | Obesity | 3 | PM | 27506289 | 📋 | Non-absorbable apple procyanidins prevent obesity associated with gut microbial and metabolomic changes |
| Apple | Obesity | 1 | PM | 25971247 | 📋 | Consumption of apples is associated with a better diet quality and reduced risk of obesity in children: National Health and Nutrition Examination Survey (NHANES) 2003-2010 |
| Apple | Overweight | 1 | PM | 12620529 | 📋 | Weight loss associated with a daily intake of three apples or three pears among overweight women |
| Apple | Postprandial Hyperglycemia | 5 | PM | 36811563 | 📋 | Chronic consumption of probiotics, oats, and apples has differential effects on postprandial bile acid profile and cardiometabolic disease risk markers compared with an isocaloric control (cornflakes): a randomized trial |
| Apple | Postprandial Hyperglycemia | 1 | PM | 35742001 | 📋 | Effect of Apple Consumption on Postprandial Blood Glucose Levels in Normal Glucose Tolerance People versus Those with Impaired Glucose Tolerance |
| Apple | Postprandial Hyperglycemia | 4 | PM | 34105575 | 📋 | Apple consumption reduces markers of postprandial inflammation following a high fat meal in overweight and obese adults: A randomized, crossover trial |
| Apple | Postprandial Hyperglycemia | 3 | PM | 33075621 | 📋 | Co-ingested vinegar-soaked or preloaded dried apple mitigated acute postprandial glycemia of rice meal in healthy subjects under equicarbohydrate conditions |
| Apple | Postprandial Hyperglycemia | 2 | PM | 32739411 | 📋 | Apple polyphenol-rich drinks dose-dependently decrease early-phase postprandial glucose concentrations following a high-carbohydrate meal: a randomized controlled trial in healthy adults and in vitro studies |
