| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Icariin | Alzheimer's Disease | 16 | PM | 38412923 | 📋 | Icariin, astragaloside a and puerarin mixture attenuates cognitive impairment in APP/PS1 mice via inhibition of ferroptosis-lipid peroxidation |
| Icariin | Alzheimer's Disease | 15 | PM | 38400523 | 📋 | Icariin ameliorates glycolytic dysfunction in Alzheimer's disease models by activating the Wnt/β-catenin signaling pathway |
| Icariin | Alzheimer's Disease | 14 | PM | 38276291 | 📋 | Study on the Pharmacological Mechanism of Icariin for the Treatment of Alzheimer's Disease Based on Network Pharmacology and Molecular Docking Techniques |
| Icariin | Alzheimer's Disease | 13 | PM | 37889523 | 📋 | Icariin improves cognitive impairment by inhibiting ferroptosis of nerve cells |
| Icariin | Alzheimer's Disease | 12 | PM | 37579923 | 📋 | Icariin improves learning and memory function in Aβ1-42-induced AD mice through regulation of the BDNF-TrκB signaling pathway |
| Icariin | Alzheimer's Disease | 11 | PM | 37229892 | 📋 | Molecular mechanisms and therapeutic potential of icariin in the treatment of Alzheimer's disease |
| Icariin | Alzheimer's Disease | 10 | PM | 37095548 | 📋 | Anti-Alzheimers molecular mechanism of icariin: insights from gut microbiota, metabolomics, and network pharmacology |
| Icariin | Alzheimer's Disease | 9 | PM | 36532735 | 📋 | HIF-1 signalling pathway was identified as a potential new pathway for Icariin's treatment against Alzheimer's disease based on preclinical evidence and bioinformatics |
| Icariin | Alzheimer's Disease | 7 | PM | 35802286 | 📋 | Icariin: A Potential Neuroprotective Agent in Alzheimer's Disease and Parkinson's Disease |
| Icariin | Alzheimer's Disease | 8 | PM | 35799540 | 📋 | Icariin ameliorates memory deficits through regulating brain insulin signaling and glucose transporters in 3×Tg-AD mice |
| Icariin | Alzheimer's Disease | 6 | PM | 35037164 | 📋 | Icariin Ameliorates Alzheimer's Disease Pathology by Alleviating Myelin Injury in 3 × Tg-AD Mice |
| Icariin | Alzheimer's Disease | 3 | PM | 34407393 | 📋 | Icariin ameliorate Alzheimer's disease by influencing SIRT1 and inhibiting Aβ cascade pathogenesis |
| Icariin | Alzheimer's Disease | 5 | PM | 33502043 | 📋 | Icaritin and icariin reduce p-Tau levels in a cell model of Alzheimer's disease by downregulating glycogen synthase kinase 3β |
| Icariin | Alzheimer's Disease | 1 | PM | 33061388 | 📋 | Effects of Co-Administration of Icariin and Panax notoginseng Saponins on Intestinal Microbiota and Hippocampal Protein Expression in a Mouse Model of Alzheimer's Disease |
| Icariin | Alzheimer's Disease | 4 | PM | 32727295 | 📋 | Icariin sustains the proliferation and differentiation of Aβ 25-35-treated hippocampal neural stem cells via the BDNF-TrkB-ERK/Akt signaling pathway |
| Icariin | Alzheimer's Disease | 2 | PM | 31612304 | 📋 | Icariin Ameliorates Amyloid Pathologies by Maintaining Homeostasis of Autophagic Systems in Aβ 1-42-Injected Rats |
| Icariin | Anxiety | 1 | PM | 38552430 | 📋 | Icariin mitigates anxiety-like behaviors induced by hemorrhagic shock and resuscitation via inhibiting of astrocytic activation |
| Icariin | Autism Spectrum Disorder | 1 | PM | 36889463 | 📋 | Icariin alleviates autistic-like behavior, hippocampal inflammation and vGlut1 expression in adult BTBR mice |
| Icariin | Cognitive Disorders | 2 | PM | 36342068 | 📋 | Effect of icariin in a rat model of colchicine-induced cognitive deficit: role of β - amyloid proteolytic enzymes |
| Icariin | Cognitive Disorders | 1 | PM | 32427716 | 📋 | Icariin improves cognitive deficits by reducing the deposition of β-amyloid peptide and inhibition of neurons apoptosis in SAMP8 mice |
| Icariin | Depression | 3 | PM | 38422651 | 📋 | Effect of icariin on depressive behaviour in rat pups. Evidences for its mechanism of action by integrating network pharmacology, metabolomics and gut microbiota composition |
| Icariin | Depression | 2 | PM | 37715385 | 📋 | Icariin prevents depression-like behaviors in chronic unpredictable mild stress-induced rats through Bax/cytoplasm C/caspase-3 axis to alleviate neuronal apoptosis |
| Icariin | Depression | 1 | PM | 31618892 | 📋 | PI3K-AKT Signaling Activation and Icariin: The Potential Effects on the Perimenopausal Depression-Like Rat Model |
| Icariin | Schizophrenia | 3 | PM | 38604555 | 📋 | Function and mechanism exploring of icariin in schizophrenia through network pharmacology |
| Icariin | Schizophrenia | 2 | PM | 37959720 | 📋 | Effects of Icariin and Its Metabolites on GPCR Regulation and MK-801-Induced Schizophrenia-Like Behaviors in Mice |
| Icariin | Schizophrenia | 1 | PM | 36261079 | 📋 | Effects of icariin on alleviating schizophrenia-like symptoms by regulating the miR-144-3p/ATP1B2/mTOR signalling pathway |
