| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Curcumin | Benign Prostatic Hyperplasia | 4 | PM | 37446563 | 📋 | Combination of Lycopene and Curcumin Synergistically Alleviates Testosterone-Propionate-Induced Benign Prostatic Hyperplasia in Sprague Dawley Rats via Modulating Inflammation and Proliferation |
| Curcumin | Benign Prostatic Hyperplasia | 3 | PM | 34532268 | 📋 | Combination therapy with curcumin plus tamsulosin and finasteride in the treatment of men with benign prostatic hyperplasia: a single center, randomized control study |
| Curcumin | Benign Prostatic Hyperplasia | 2 | PM | 34357837 | 📋 | Curcumin attenuates prostatic hyperplasia caused by inflammation via up-regulation of bone morphogenetic protein and activin membrane-bound inhibitor |
| Curcumin | Benign Prostatic Hyperplasia | 1 | PM | 23241931 | 📋 | Meriva®, a Lecithinized Curcumin Delivery System, in the Control of Benign Prostatic Hyperplasia: A Pilot, Product Evaluation Registry Study |
| Curcumin | Chronic Prostatitis | 4 | PM | 34914324 | 📋 | [Lycopene combined with quercetin and curcumin for chronic prostatitis/chronic pelvic pain syndrome in rats: Effect and mechanism] |
| Curcumin | Chronic Prostatitis | 3 | PM | 28679180 | 📋 | A phase II, randomized, single-blinded, placebo-controlled clinical trial on the efficacy of Curcumina and Calendula suppositories for the treatment of patients with chronic prostatitis/chronic pelvic pain syndrome type III |
| Curcumin | Chronic Prostatitis | 2 | PM | 20180411 | 📋 | [Reducing Effect of Curcumin on Expressions of TNF-alpha, IL-6 and IL-8 in Rats With Chronic Nonbacterial Prostatitis] |
| Curcumin | Chronic Prostatitis | 1 | PM | 19181486 | 📋 | Serenoa Repens Associated With Urtica Dioica (ProstaMEV) and Curcumin and Quercitin (FlogMEV) Extracts Are Able to Improve the Efficacy of Prulifloxacin in Bacterial Prostatitis Patients: Results From a Prospective Randomised Study |
| Curcumin | Gonorrhea | 2 | PM | 23642399 | 📋 | The Possible Roles of Vitamin D and Curcumin in Treating Gonorrhea |
| Curcumin | Gonorrhea | 1 | PM | 15927892 | 📋 | The Anti-Inflammatory Compound Curcumin Inhibits Neisseria Gonorrhoeae-Induced NF-kappaB Signaling, Release of Pro-Inflammatory Cytokines/Chemokines and Attenuates Adhesion in Late Infection |
| Curcumin | Infertility | 1 | PM | 35041229 | 📋 | An overview of the therapeutic effects of curcumin in reproductive disorders with a focus on the antiinflammatory and immunomodulatory activities |
| Curcumin | Infertility Male | 12 | PM | 37744019 | 📋 | The effects of coadministration of curcumin and vitamin E on the reproductive system of diabetic male rats; An experimental study |
| Curcumin | Infertility Male | 11 | PM | 36077406 | 📋 | Curcumin Remedies Testicular Function and Spermatogenesis in Male Mice with Low-Carbohydrate-Diet-Induced Metabolic Dysfunction |
| Curcumin | Infertility Male | 10 | PM | 34981481 | 📋 | Protective Effects of Curcumin in the Reproductive System: Anti-toxic, Semen Cryopreservative, and Contraceptive Actions |
| Curcumin | Infertility Male | 9 | PM | 32748946 | 📋 | The ameliorative effect of curcumin on cryptorchid and non-cryptorchid testes in induced unilateral cryptorchidism in albino rat: histological evaluation |
| Curcumin | Infertility Male | 1 | PM | 32293755 | 📋 | Effects of Curcumin on Sperm Quality, Lipid Profile, Antioxidant Activity and Histopathological Changes in Streptozotocin-Induced Diabetes in Rats |
| Curcumin | Infertility Male | 2 | PM | 27600729 | 📋 | Curcumin Ameliorates High‑fat Diet‑induced Spermatogenesis Dysfunction |
| Curcumin | Infertility Male | 3 | PM | 27377223 | 📋 | Curcumin Has Protective and Antioxidant Properties on Bull Spermatozoa Subjected to Induced Oxidative Stress |
| Curcumin | Infertility Male | 4 | PM | 25149981 | 📋 | Curcumin Influences Semen Quality Parameters and Reverses the di(2-ethylhexyl)phthalate (DEHP)-induced Testicular Damage in Mice |
| Curcumin | Infertility Male | 5 | PM | 22257170 | 📋 | Ameliorative Effects of Curcumin Against Acute Cadmium Toxicity on Male Reproductive System in Rats |
| Curcumin | Infertility Male | 6 | PM | 21632575 | 📋 | Anti-apoptotic Effects of Curcumin on Cadmium-Induced Apoptosis in Rat Testes |
| Curcumin | Infertility Male | 7 | PM | 20182699 | 📋 | Protective Role of Curcumin on Lindane Induced Reproductive Toxicity in Male Wistar Rats |
| Curcumin | Infertility Male | 8 | PM | 18971866 | 📋 | Curcumin Protects Leydig Cells of Mice From Damage Induced by Chronic Alcohol Administration |
| Curcumin | Prostate Cancer | 72 | PM | 38783940 | 📋 | Application and potential value of curcumin in prostate cancer: a meta-analysis based on animal models |
| Curcumin | Prostate Cancer | 71 | PM | 38374014 | 📋 | Curcumin Enhances the Anti-Cancer Efficacy of CDK4/6 Inhibitors in Prostate Cancer |
| Curcumin | Prostate Cancer | 70 | PM | 38348716 | 📋 | Curcumin inhibits prostate cancer by upregulating miR-483-3p and inhibiting UBE2C |
| Curcumin | Prostate Cancer | 36 | PM | 38229314 | 📋 | New mode of action of curcumin on prostate cancer cells: Modulation of endoplasmic reticulum-associated degradation mechanism and estrogenic signaling |
| Curcumin | Prostate Cancer | 69 | PM | 37776274 | 📋 | Effects of curcumin and ursolic acid in prostate cancer: A systematic review |
| Curcumin | Prostate Cancer | 68 | PM | 37663388 | 📋 | Cytotoxicity of curcumin against CD44± prostate cancer cells: Roles of miR-383 and miR-708 |
| Curcumin | Prostate Cancer | 67 | PM | 37509660 | 📋 | Enhancing the Anticancer and Anti-Inflammatory Properties of Curcumin in Combination with Quercetin, for the Prevention and Treatment of Prostate Cancer |
| Curcumin | Prostate Cancer | 66 | PM | 36572324 | 📋 | Curcuminoids inhibit human and rat placental 3β-hydroxysteroid dehydrogenases: Structure-activity relationship and in silico docking analysis |
| Curcumin | Prostate Cancer | 65 | PM | 36498267 | 📋 | Effects of Curcumin and Lactoferrin to Inhibit the Growth and Migration of Prostatic Cancer Cells |
| Curcumin | Prostate Cancer | 64 | PM | 35868335 | 📋 | Curcumin Upregulates miR-148a to Increase the Chemosensitivity of CD44-Positive Prostate Cancer Stem Cells to Paclitaxel Through Targeting the MSK1/IRS1 axis |
| Curcumin | Prostate Cancer | 63 | PM | 35855104 | 📋 | Review On the Effects Curcumin on Tumors of the Reproductive System: Curcumin and Reproductive Tumors |
| Curcumin | Prostate Cancer | 62 | PM | 35487055 | 📋 | Human prostate cancer cell epithelial-to-mesenchymal transition as a novel target of arsenic trioxide and curcumin therapeutic approach |
| Curcumin | Prostate Cancer | 61 | PM | 34679726 | 📋 | Curcumin and Carnosic Acid Cooperate to Inhibit Proliferation and Alter Mitochondrial Function of Metastatic Prostate Cancer Cells |
| Curcumin | Prostate Cancer | 60 | PM | 34576132 | 📋 | Growth, Proliferation and Metastasis of Prostate Cancer Cells Is Blocked by Low-Dose Curcumin in Combination with Light Irradiation |
| Curcumin | Prostate Cancer | 59 | PM | 34335911 | 📋 | Curcumin inhibits prostate cancer progression by regulating the miR-30a-5p/PCLAF axis |
| Curcumin | Prostate Cancer | 58 | PM | 34095313 | 📋 | Curcumin Targets Both Apoptosis and Necroptosis in Acidity-Tolerant Prostate Carcinoma Cells |
| Curcumin | Prostate Cancer | 57 | PM | 34070833 | 📋 | Dietary Phytochemicals in Zinc Homeostasis: A Strategy for Prostate Cancer Management |
| Curcumin | Prostate Cancer | 56 | PM | 33499881 | 📋 | Targeting androgen receptor signaling with MicroRNAs and Curcumin: a promising therapeutic approach for Prostate Cancer Prevention and intervention |
| Curcumin | Prostate Cancer | 55 | PM | 33182828 | 📋 | Curcumin against Prostate Cancer: Current Evidence |
| Curcumin | Prostate Cancer | 54 | PM | 33010228 | 📋 | Curcumin promotes cancer-associated fibroblasts apoptosis via ROS-mediated endoplasmic reticulum stress |
| Curcumin | Prostate Cancer | 53 | PM | 32657143 | 📋 | Combination of Curcumin and Metformin Inhibits Cell Growth and Induces Apoptosis without Affecting the Cell Cycle in LNCaP Prostate Cancer Cell Line |
| Curcumin | Prostate Cancer | 10 | PM | 29485738 | 📋 | Curcumin Suppressed the Prostate Cancer by Inhibiting JNK Pathways via Epigenetic Regulation |
| Curcumin | Prostate Cancer | 44 | PM | 28628644 | 📋 | Targeting Multiple Pro-Apoptotic Signaling Pathways With Curcumin in Prostate Cancer Cells |
| Curcumin | Prostate Cancer | 18 | PM | 28199187 | 📋 | Combinatorial Effect of Curcumin With Docetaxel Modulates Apoptotic and Cell Survival Molecules in Prostate Cancer |
| Curcumin | Prostate Cancer | 49 | PM | 27132804 | 📋 | Sensitization of Androgen Refractory Prostate Cancer Cells to Anti-Androgens Through Re-Expression of Epigenetically Repressed Androgen Receptor - Synergistic Action of Quercetin and Curcumin |
| Curcumin | Prostate Cancer | 52 | PM | 27018446 | 📋 | Molecular Mechanisms of Curcumin and Its Semisynthetic Analogues in Prostate Cancer Prevention and Treatment |
| Curcumin | Prostate Cancer | 5 | PM | 26771576 | 📋 | The New Combination Docetaxel, Prednisone and Curcumin in Patients With Castration-Resistant Prostate Cancer: A Pilot Phase II Study |
| Curcumin | Prostate Cancer | 51 | PM | 26718024 | 📋 | Theracurmin® Efficiently Inhibits the Growth of Human Prostate and Bladder Cancer Cells via Induction of Apoptotic Cell Death and Cell Cycle Arrest |
| Curcumin | Prostate Cancer | 14 | PM | 26630272 | 📋 | Combination of α-Tomatine and Curcumin Inhibits Growth and Induces Apoptosis in Human Prostate Cancer Cells |
| Curcumin | Prostate Cancer | 15 | PM | 26499200 | 📋 | Curcumin Inhibits Cancer-Associated Fibroblast-Driven Prostate Cancer Invasion Through MAOA/mTOR/HIF-1α Signaling |
| Curcumin | Prostate Cancer | 11 | PM | 26366279 | 📋 | Effect of Curcumin on the Interaction Between Androgen Receptor and Wnt/β-catenin in LNCaP Xenografts |
| Curcumin | Prostate Cancer | 48 | PM | 25594891 | 📋 | Curcumin-based Anti-Prostate Cancer Agents |
| Curcumin | Prostate Cancer | 1 | PM | 25243063 | 📋 | Increased Chemopreventive Effect by Combining Arctigenin, Green Tea Polyphenol and Curcumin in Prostate and Breast Cancer Cells |
| Curcumin | Prostate Cancer | 12 | PM | 23042094 | 📋 | Curcumin Inhibits Prostate Cancer Metastasis in Vivo by Targeting the Inflammatory Cytokines CXCL1 and -2 |
| Curcumin | Prostate Cancer | 43 | PM | 21938566 | 📋 | Epigenetic CpG Demethylation of the Promoter and Reactivation of the Expression of Neurog1 by Curcumin in Prostate LNCaP Cells |
| Curcumin | Prostate Cancer | 30 | PM | 21240460 | 📋 | Anti-proliferative Potential of Curcumin in Androgen-Dependent Prostate Cancer Cells Occurs Through Modulation of the Wingless Signaling Pathway |
| Curcumin | Prostate Cancer | 50 | PM | 21134073 | 📋 | Testosterone Augments Polyphenol-Induced DNA Damage Response in Prostate Cancer Cell Line, LNCaP |
| Curcumin | Prostate Cancer | 26 | PM | 20680030 | 📋 | Curcumin Interrupts the Interaction Between the Androgen Receptor and Wnt/β-catenin Signaling Pathway in LNCaP Prostate Cancer Cells |
| Curcumin | Prostate Cancer | 4 | PM | 20503397 | 📋 | Combined Inhibitory Effects of Soy Isoflavones and Curcumin on the Production of Prostate-Specific Antigen |
| Curcumin | Prostate Cancer | 35 | PM | 20358476 | 📋 | Curcumin-induced Apoptosis in PC3 Prostate Carcinoma Cells Is Caspase-Independent and Involves Cellular Ceramide Accumulation and Damage to Mitochondria |
| Curcumin | Prostate Cancer | 45 | PM | 20099188 | 📋 | Possible Benefits of Curcumin Regimen in Combination With Taxane Chemotherapy for Hormone-Refractory Prostate Cancer Treatment |
| Curcumin | Prostate Cancer | 29 | PM | 19806380 | 📋 | Chemopreventive Potential of Curcumin in Prostate Cancer |
| Curcumin | Prostate Cancer | 9 | PM | 19772879 | 📋 | Multifunctional Role of VIP in Prostate Cancer Progression in a Xenograft Model: Suppression by Curcumin and COX-2 Inhibitor NS-398 |
| Curcumin | Prostate Cancer | 16 | PM | 19538771 | 📋 | An Evaluation of the Anti-Neoplastic Activity of Curcumin in Prostate Cancer Cell Lines |
| Curcumin | Prostate Cancer | 17 | PM | 19360344 | 📋 | Curcumin Blocks CCL2-induced Adhesion, Motility and Invasion, in Part, Through Down-Regulation of CCL2 Expression and Proteolytic Activity |
| Curcumin | Prostate Cancer | 2 | PM | 19326431 | 📋 | Liposome Encapsulation of Curcumin and Resveratrol in Combination Reduces Prostate Cancer Incidence in PTEN Knockout Mice |
| Curcumin | Prostate Cancer | 37 | PM | 19086645 | 📋 | [Curcumin Inhibits Growth, Induces G1 Arrest and Apoptosis on Human Prostatic Stromal Cells by Regulating Bcl-2/Bax] |
| Curcumin | Prostate Cancer | 42 | PM | 18719366 | 📋 | Androgen Responsive and Refractory Prostate Cancer Cells Exhibit Distinct Curcumin Regulated Transcriptome |
| Curcumin | Prostate Cancer | 40 | PM | 18676361 | 📋 | Curcumin Blocks the Activation of Androgen and interlukin-6 on Prostate-Specific Antigen Expression in Human Prostatic Carcinoma Cells |
| Curcumin | Prostate Cancer | 7 | PM | 18437538 | 📋 | Murine Prostate Cancer Inhibition by Dietary Phytochemicals--Curcumin and Phenyethylisothiocyanate |
| Curcumin | Prostate Cancer | 19 | PM | 18390174 | 📋 | [Curcumin Inhibits the Expression of Vascular Endothelial Growth Factor and Androgen-Independent Prostate Cancer Cell Line PC-3 in Vitro] |
| Curcumin | Prostate Cancer | 46 | PM | 17289836 | 📋 | Curcumin [1,7-bis(4-hydroxy-3-methoxyphenyl)-1-6-heptadine-3,5-dione; C21H20O6] Sensitizes Human Prostate Cancer Cells to Tumor Necrosis Factor-Related Apoptosis-Inducing ligand/Apo2L-induced Apoptosis by Suppressing Nuclear factor-kappaB via Inhibition of the Prosurvival Akt Signaling Pathway |
| Curcumin | Prostate Cancer | 3 | PM | 17151092 | 📋 | Chemopreventive Anti-Inflammatory Activities of Curcumin and Other Phytochemicals Mediated by MAP Kinase phosphatase-5 in Prostate Cells |
| Curcumin | Prostate Cancer | 32 | PM | 17147887 | 📋 | [Curcumin-induced the Expression of Inhibitor kappaBalpha Protein in Human Prostate Cancer Cells] |
| Curcumin | Prostate Cancer | 41 | PM | 16787365 | 📋 | Curcumin Is an Inhibitor of p300 Histone Acetylatransferase |
| Curcumin | Prostate Cancer | 33 | PM | 16519151 | 📋 | [Curcumin-induced Apoptosis in Androgen-Dependent Prostate Cancer Cell Line LNCaP in Vitro] |
| Curcumin | Prostate Cancer | 20 | PM | 16471035 | 📋 | Chemosensitization of Hormone-Refractory Prostate Cancer Cells by Curcumin to TRAIL-induced Apoptosis |
| Curcumin | Prostate Cancer | 6 | PM | 16423986 | 📋 | Combined Inhibitory Effects of Curcumin and Phenethyl Isothiocyanate on the Growth of Human PC-3 Prostate Xenografts in Immunodeficient Mice |
| Curcumin | Prostate Cancer | 39 | PM | 16342680 | 📋 | [Inhibition of the Expression of Prostate Specific Antigen by Curcumin] |
| Curcumin | Prostate Cancer | 13 | PM | 16299382 | 📋 | Inhibition of EGFR Signaling in Human Prostate Cancer PC-3 Cells by Combination Treatment With Beta-Phenylethyl Isothiocyanate and Curcumin |
| Curcumin | Prostate Cancer | 47 | PM | 15252141 | 📋 | Curcumin Sensitizes Prostate Cancer Cells to Tumor Necrosis Factor-Related Apoptosis-Inducing ligand/Apo2L by Inhibiting Nuclear factor-kappaB Through Suppression of IkappaBalpha Phosphorylation |
| Curcumin | Prostate Cancer | 28 | PM | 15236356 | 📋 | Curcumin Inhibits Cell Motility and Alters Microfilament Organization and Function in Prostate Cancer Cells |
| Curcumin | Prostate Cancer | 25 | PM | 15129424 | 📋 | Therapeutic Potential of Curcumin in Prostate cancer--V: Interference With the Osteomimetic Properties of Hormone Refractory C4-2B Prostate Cancer Cells |
| Curcumin | Prostate Cancer | 21 | PM | 14985701 | 📋 | Curcumin Confers Radiosensitizing Effect in Prostate Cancer Cell Line PC-3 |
| Curcumin | Prostate Cancer | 38 | PM | 12682902 | 📋 | Inhibition of Cell Survival Signal Protein Kinase B/Akt by Curcumin in Human Prostate Cancer Cells |
| Curcumin | Prostate Cancer | 24 | PM | 12533677 | 📋 | Curcumin (Diferuloyl-Methane) Enhances Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Induced Apoptosis in LNCaP Prostate Cancer Cells |
| Curcumin | Prostate Cancer | 34 | PM | 12497104 | 📋 | Therapeutic Potential of Curcumin in Human Prostate cancer-I. Curcumin Induces Apoptosis in Both Androgen-Dependent and Androgen-Independent Prostate Cancer Cells |
| Curcumin | Prostate Cancer | 27 | PM | 12239622 | 📋 | Curcumin Down-Regulates AR Gene Expression and Activation in Prostate Cancer Cell Lines |
| Curcumin | Prostate Cancer | 23 | PM | 11967955 | 📋 | Curcumin Enhances Cytotoxicity of Chemotherapeutic Agents in Prostate Cancer Cells by Inducing p21(WAF1/CIP1) and C/EBPbeta Expressions and Suppressing NF-kappaB Activation |
| Curcumin | Prostate Cancer | 22 | PM | 11753638 | 📋 | Curcumin Downregulates Cell Survival Mechanisms in Human Prostate Cancer Cell Lines |
| Curcumin | Prostate Cancer | 8 | PM | 11398177 | 📋 | Therapeutic Potential of Curcumin in Human Prostate Cancer. III. Curcumin Inhibits Proliferation, Induces Apoptosis, and Inhibits Angiogenesis of LNCaP Prostate Cancer Cells in Vivo |
| Curcumin | Prostate Cancer | 31 | PM | 10851300 | 📋 | Therapeutic Potential of Curcumin in Human Prostate Cancer. II. Curcumin Inhibits Tyrosine Kinase Activity of Epidermal Growth Factor Receptor and Depletes the Protein |
| Curcumin | Prostate Disorders | 2 | PM | 34838672 | 📋 | Protective effect of the association of curcumin with piperine on prostatic lesions: New perspectives on BPA-induced carcinogenesis |
| Curcumin | Prostate Disorders | 1 | PM | 34331700 | 📋 | Curcumin for the Treatment of Prostate Diseases: A Systematic Review of Controlled Clinical Trials |
| Curcumin | Reproductive Toxicity Male | 8 | PM | 38841432 | 📋 | Curcumin protects against cadmium-induced germ cell death in the testis of rats |
| Curcumin | Reproductive Toxicity Male | 7 | PM | 38095090 | 📋 | Curcumin attenuates diphenyl phosphate-induced apoptosis in GC-2spd(ts) cells through activated autophagy via the Nrf2/P53 pathway |
| Curcumin | Reproductive Toxicity Male | 6 | PM | 37966654 | 📋 | Curcumin strengthens a spontaneous self-protective mechanism-SP1/PRDX6 pathway, against di-n-butyl phthalate-induced testicular ferroptosis damage |
| Curcumin | Reproductive Toxicity Male | 5 | PM | 35437774 | 📋 | Curcumin improves the protective effects of quercetin against atrazine-induced testicular injury in adult Wistar rats |
| Curcumin | Reproductive Toxicity Male | 3 | PM | 34352168 | 📋 | Protective effects of curcumin against methotrexate-induced testicular damage in rats by suppression of the p38-MAPK and nuclear factor-kappa B pathways |
| Curcumin | Reproductive Toxicity Male | 2 | PM | 33919028 | 📋 | A Flavonoid-Rich Extract from Bergamot Juice, Alone or in Association with Curcumin and Resveratrol, Shows Protective Effects in a Murine Model of Cadmium-Induced Testicular Injury |
| Curcumin | Reproductive Toxicity Male | 1 | PM | 33289171 | 📋 | Comparison of the protective effects of curcumin and caffeic acid phenethyl ester against doxorubicin-induced testicular toxicity |
| Curcumin | Reproductive Toxicity Male | 4 | PM | 32569592 | 📋 | Cyclosporine a Induces Testicular Injury via Mitochondrial Apoptotic Pathway by Regulation of mir-34a and sirt-1 in Male Rats: The Rescue Effect of Curcumin |
| Curcumin | Testicular Cancer | 1 | PM | 32875900 | 📋 | Heterogeneous Differentiation of Highly Proliferative Embryonal Carcinoma PCC4 Cells Induced by Curcumin: An In Vitro Study |
| Curcumin | Testicular Torsion | 2 | PM | 33648042 | 📋 | Protective effects of curcumin on chromatin quality, sperm parameters, and apoptosis following testicular torsion-detorsion in mice |
| Curcumin | Testicular Torsion | 1 | PM | 18222428 | 📋 | Curcumin Attenuates Ischemia-Reperfusion Injury in Rat Testis |
| Curcumin | Varicocele | 1 | PM | 34755901 | 📋 | Effect of curcumin, and nano-curcumin on sperm function in varicocele rat model |
