| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Vitamin C | Aging Liver | 1 | PM | 37611505 | 📋 | Effects of swimming exercise combined with silymarin and vitamin C supplementation on hepatic inflammation, oxidative stress, and histopathology in elderly rats with high-fat diet-induced liver damage |
| Vitamin C | Alcoholic Liver Disease | 1 | PM | 34921864 | 📋 | Vitamin C alleviates alcoholic liver injury by suppressing neutrophil infiltration in senescence marker protein 30-knockout mice irrespective of its antioxidant effects |
| Vitamin C | Alcoholic Liver Disease | 2 | PM | 23653339 | 📋 | Ascorbic acid is superior to silymarin in the recovery of ethanol-induced inflammatory reactions in hepatocytes of guinea pigs |
| Vitamin C | Cholestasis | 1 | PM | 17106933 | 📋 | Antioxidants vitamin E and C attenuate hepatic fibrosis in biliary-obstructed rats |
| Vitamin C | Cholestasis | 2 | PM | 7205399 | 📋 | Influence of chronic ascorbic acid deficiency and excessive ascorbic acid intake on bile acid metabolism and bile composition in the guinea pig |
| Vitamin C | Hepatic Encephalopathy | 1 | PM | 36034085 | 📋 | Protective effect of probiotics and ascorbic acid on bile duct ligation-induced chronic hepatic encephalopathy in rats |
| Vitamin C | Hepatic Fibrosis | 3 | PM | 35189786 | 📋 | Association of serum vitamin C with liver fibrosis in adults with nonalcoholic fatty liver disease |
| Vitamin C | Hepatic Fibrosis | 2 | PM | 26057690 | 📋 | Hepatoprotective effect of vitamin C on lithocholic acid-induced cholestatic liver injury in Gulo(-/-) mice |
| Vitamin C | Hepatic Fibrosis | 4 | PM | 24239723 | 📋 | Ascorbic acid suppresses endotoxemia and NF-κB signaling cascade in alcoholic liver fibrosis in guinea pigs: a mechanistic approach |
| Vitamin C | Hepatic Fibrosis | 1 | PM | 17106933 | 📋 | Antioxidants vitamin E and C attenuate hepatic fibrosis in biliary-obstructed rats |
| Vitamin C | Hepatitis | 1 | PM | 23472641 | 📋 | In vivo consequence of vitamin C insufficiency in liver injury: vitamin C ameliorates T-cell-mediated acute liver injury in gulo(-/-) mice |
| Vitamin C | Hepatitis A | 2 | PM | 3266046 | 📋 | [Ascorbic acid level and the indicators of cellular immunity in patients with hepatitis A during pathogenetic therapy] |
| Vitamin C | Hepatitis A | 1 | PM | 2633390 | 📋 | [Humoral and cellular indices of nonspecific resistance in viral hepatitis A and ascorbic acid] |
| Vitamin C | Hepatitis C | 4 | PM | 35668562 | 📋 | Vitamin C supplementation ameliorates liver function profile and antiviral treatment response in Hepatitis C patients |
| Vitamin C | Hepatitis C | 2 | PM | 17441803 | 📋 | High-dose vitamins E and C supplementation prevents ribavirin-induced hemolytic anemia in patients with chronic hepatitis C |
| Vitamin C | Hepatitis C | 3 | PM | 16459223 | 📋 | Vitamin E and C supplementation prevents decrease of eicosapentaenoic acid in mononuclear cells in chronic hepatitis C patients during combination therapy of interferon alpha-2b and ribavirin |
| Vitamin C | Hepatitis C | 1 | PM | 16082287 | 📋 | Treatment of Chronic Hepatitis C Virus Infection via Antioxidants: Results of a Phase I Clinical Trial |
| Vitamin C | Hepatotoxicity | 11 | PM | 37140282 | 📋 | Vitamin C as a potential ameliorating agent against hepatotoxicity among alcoholic abusers |
| Vitamin C | Hepatotoxicity | 10 | PM | 37013745 | 📋 | Elucidation of the role of α-lipoic acid and vitamin C in methotrexate-induced hepatoxicity in mice |
| Vitamin C | Hepatotoxicity | 9 | PM | 35492324 | 📋 | Combination of Vitamin C and Curcumin Safeguards Against Methotrexate-Induced Acute Liver Injury in Mice by Synergistic Antioxidant Effects |
| Vitamin C | Hepatotoxicity | 4 | PM | 35024202 | 📋 | Integrative omics analysis reveals the protective role of vitamin C on perfluorooctanoic acid-induced hepatoxicity |
| Vitamin C | Hepatotoxicity | 2 | PM | 31798354 | 📋 | Vitamin C and Turmeric Attenuate Bax and Bcl-2 Proteins' Expressions and DNA Damage in Lead Acetate-Induced Liver Injury |
| Vitamin C | Hepatotoxicity | 6 | PM | 31199767 | 📋 | Role of antioxidant supplementation in oxidant/antioxidant status and hepatotoxic effects due to aflatoxin B1 in wheat miller workers |
| Vitamin C | Hepatotoxicity | 5 | PM | 31117289 | 📋 | Hepatoprotective Actions of Ascorbic Acid, Alpha Lipoic Acid and Silymarin or Their Combination Against Acetaminophen-Induced Hepatotoxicity in Rats |
| Vitamin C | Hepatotoxicity | 3 | PM | 30714529 | 📋 | In Vitro Protective Effect of Ascorbic Acid Against Antibiotic-Induced Hepatotoxicity |
| Vitamin C | Hepatotoxicity | 8 | PM | 30272083 | 📋 | Dual action of vitamin C in iron supplement therapeutics for iron deficiency anemia: prevention of liver damage induced by iron overload |
| Vitamin C | Hepatotoxicity | 7 | PM | 30087544 | 📋 | Effects of vitamin C and E on toxic action of alcohol on partial hepatectomy-induced liver regeneration in rats |
| Vitamin C | Hepatotoxicity | 1 | PM | 26810168 | 📋 | Vitamin C ameliorates high dose Dexmedetomidine induced liver injury |
| Vitamin C | Liver Cancer | 19 | PM | 38822322 | 📋 | Metabolomics reveals ascorbic acid inhibits ferroptosis in hepatocytes and boosts the effectiveness of anti-PD1 immunotherapy in hepatocellular carcinoma |
| Vitamin C | Liver Cancer | 18 | PM | 36809998 | 📋 | Biochemical and pathophysiological improvements in rats with thioacetamide induced-hepatocellular carcinoma using aspirin plus vitamin C |
| Vitamin C | Liver Cancer | 16 | PM | 34504430 | 📋 | Ascorbic Acid Inhibits Liver Cancer Growth and Metastasis in vitro and in vivo, Independent of Stemness Gene Regulation |
| Vitamin C | Liver Cancer | 15 | PM | 33349056 | 📋 | A Study on the Effect of Vitamins A and C to Modulate the Expression of NKG2D Ligands in Hepatic and Colon Cancer Cells |
| Vitamin C | Liver Cancer | 17 | PM | 32805337 | 📋 | Ascorbic acid prevents N-nitrosodiethylamine-induced hepatic injury and hepatocarcinogenesis in Akr1a-knockout mice |
| Vitamin C | Liver Cancer | 5 | PM | 31754384 | 📋 | Hepatomas are exquisitely sensitive to pharmacologic ascorbate (P-AscH -) |
| Vitamin C | Liver Cancer | 9 | PM | 31281544 | 📋 | Ascorbic acid induced HepG2 cells' apoptosis via intracellular reductive stress |
| Vitamin C | Liver Cancer | 14 | PM | 29872720 | 📋 | Vitamin C preferentially kills cancer stem cells in hepatocellular carcinoma via SVCT-2 |
| Vitamin C | Liver Cancer | 4 | PM | 29669302 | 📋 | Cytotoxic and partial hepatoprotective activity of sodium ascorbate against hepatocellular carcinoma through inhibition of sulfatase-2 in vivo and in vitro |
| Vitamin C | Liver Cancer | 2 | PM | 28894987 | 📋 | The induction of apoptosis and autophagy in human hepatoma SMMC-7721 cells by combined treatment with vitamin C and polysaccharides extracted from Grifola frondosa |
| Vitamin C | Liver Cancer | 11 | PM | 28192139 | 📋 | Vitamin C down-regulate apo(a) expression via Tet2-dependent DNA demethylation in HepG2 cells |
| Vitamin C | Liver Cancer | 10 | PM | 27151580 | 📋 | Synergistic Apoptotic Effect of D-Fraction From Grifola frondosa and Vitamin C on Hepatocellular Carcinoma SMMC-7721 Cells |
| Vitamin C | Liver Cancer | 13 | PM | 27134688 | 📋 | Vitamin C enhances epigenetic modifications induced by 5-azacytidine and cell cycle arrest in the hepatocellular carcinoma cell lines HLE and Huh7 |
| Vitamin C | Liver Cancer | 3 | PM | 27036367 | 📋 | Synergistic effects of ascorbate and sorafenib in hepatocellular carcinoma: New insights into ascorbate cytotoxicity |
| Vitamin C | Liver Cancer | 12 | PM | 24969544 | 📋 | Vitamin C enhances anticancer activity in methotrexate‑treated Hep3B hepatocellular carcinoma cells |
| Vitamin C | Liver Cancer | 8 | PM | 21116852 | 📋 | Effects of ascorbic acid and β-carotene on HepG2 human hepatocellular carcinoma cell line |
| Vitamin C | Liver Cancer | 6 | PM | 20693968 | 📋 | In vivo and In vitro effect of a nutrient mixture on human hepatocarcinoma cell line SK-HEP-1 |
| Vitamin C | Liver Cancer | 7 | PM | 15004519 | 📋 | Ascorbate potentiates the cytotoxicity of menadione leading to an oxidative stress that kills cancer cells by a non-apoptotic caspase-3 independent form of cell death |
| Vitamin C | Liver Cancer | 1 | PM | 9834927 | 📋 | Vitamin C and Aloe Vera Supplementation Protects From Chemical Hepatocarcinogenesis in the Rat |
| Vitamin C | Liver Damage | 2 | PM | 35496049 | 📋 | Combination Treatment of Omega-3 Fatty Acids and Vitamin C Exhibited Promising Therapeutic Effect against Oxidative Impairment of the Liver in Methotrexate-Intoxicated Mice |
| Vitamin C | Liver Damage | 1 | PM | 35392606 | 📋 | Ascorbic Acid Ameriolates Liver Damage by Myeloperoxidase Oxidative Products in a Hamster Model of Amoebic Liver Abscess |
| Vitamin C | Liver Damage | 9 | PM | 30530052 | 📋 | Therapeutic targets of vitamin C on liver injury and associated biological mechanisms: A study of network pharmacology |
| Vitamin C | Liver Disease | 1 | PM | 23472641 | 📋 | In vivo consequence of vitamin C insufficiency in liver injury: vitamin C ameliorates T-cell-mediated acute liver injury in gulo(-/-) mice |
| Vitamin C | MAFLD | 8 | PM | 38635545 | 📋 | Potassium affects the association between dietary intake of vitamin C and NAFLD among adults in the United States |
| Vitamin C | MAFLD | 7 | PM | 37089915 | 📋 | Vitamin C and vitamin D3 alleviate metabolic-associated fatty liver disease by regulating the gut microbiota and bile acid metabolism via the gut-liver axis |
| Vitamin C | MAFLD | 6 | PM | 33152949 | 📋 | Prophylactic and therapeutic effects of different doses of vitamin C on high-fat-diet-induced non-alcoholic fatty liver disease in mice |
| Vitamin C | MAFLD | 5 | PM | 33080906 | 📋 | Silymarin in Combination with Vitamin C, Vitamin E, Coenzyme Q10 and Selenomethionine to Improve Liver Enzymes and Blood Lipid Profile in NAFLD Patients |
| Vitamin C | MAFLD | 4 | PM | 31322211 | 📋 | Ascorbic acid attenuates cell stress by activating the fibroblast growth factor 21/fibroblast growth factor receptor 2/adiponectin pathway in HepG2 cells |
| Vitamin C | MAFLD | 1 | PM | 31281067 | 📋 | Dietary vitamin E and C intake is inversely associated with the severity of nonalcoholic fatty liver disease |
| Vitamin C | MAFLD | 3 | PM | 30283077 | 📋 | Ascorbic acid inhibits visceral obesity and nonalcoholic fatty liver disease by activating peroxisome proliferator-activated receptor α in high-fat-diet-fed C57BL/6J mice |
| Vitamin C | MAFLD | 2 | PM | 26824361 | 📋 | Association between Dietary Vitamin C Intake and Non-Alcoholic Fatty Liver Disease: A Cross-Sectional Study among Middle-Aged and Older Adults |
| Vitamin C | Non-Alcoholic Steatohepatitis | 2 | PM | 35683997 | 📋 | Mega-Dose Vitamin C Ameliorates Nonalcoholic Fatty Liver Disease in a Mouse Fast-Food Diet Model |
| Vitamin C | Non-Alcoholic Steatohepatitis | 1 | PM | 31782040 | 📋 | Vitamin C inhibits lipid deposition through GSK-3β/mTOR signaling in the liver of zebrafish |
