| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Sulforaphane | Acute Liver Failure | 1 | PM | 37620223 | 📋 | Sulforaphane, an NRF2 agonist, alleviates ferroptosis in acute liver failure by regulating HDAC6 activity |
| Sulforaphane | Acute Liver Injury | 1 | PM | 30821482 | 📋 | Hepatic protective effects of sulforaphane through the modulation of inflammatory pathways |
| Sulforaphane | Alcoholic Liver Disease | 2 | PM | 33388347 | 📋 | Sulforaphane ameliorates ethanol plus carbon tetrachloride-induced liver fibrosis in mice through the Nrf2-mediated antioxidant response and acetaldehyde metabolization with inhibition of the LPS/TLR4 signaling pathway |
| Sulforaphane | Alcoholic Liver Disease | 1 | PM | 33100876 | 📋 | Protective effects of sulforaphane and aerobic exercise on acute alcoholic hepatic injury in mice |
| Sulforaphane | Hepatic Fibrosis | 2 | PM | 33388347 | 📋 | Sulforaphane ameliorates ethanol plus carbon tetrachloride-induced liver fibrosis in mice through the Nrf2-mediated antioxidant response and acetaldehyde metabolization with inhibition of the LPS/TLR4 signaling pathway |
| Sulforaphane | Hepatic Fibrosis | 1 | PM | 31278688 | 📋 | Sulforaphane inhibits the activation of hepatic stellate cell by miRNA-423-5p targeting suppressor of fused |
| Sulforaphane | Hepatic Ischemia-Reperfusion | 3 | PM | 38203749 | 📋 | Sulforaphane Is Protective against Warm Ischemia/Reperfusion Injury and Partial Hepatectomy in Rats |
| Sulforaphane | Hepatic Ischemia-Reperfusion | 2 | PM | 35222401 | 📋 | Sulforaphane Exerts Beneficial Immunomodulatory Effects on Liver Tissue via a Nrf2 Pathway-Related Mechanism in a Murine Model of Hemorrhagic Shock and Resuscitation |
| Sulforaphane | Hepatic Ischemia-Reperfusion | 1 | PM | 34320386 | 📋 | Sulforaphane alleviates hepatic ischemia-reperfusion injury through promoting the activation of Nrf-2/HO-1 signaling |
| Sulforaphane | Hepatic Steatosis | 2 | PM | 35610278 | 📋 | Sulforaphane suppresses the activity of sterol regulatory element-binding proteins (SREBPs) by promoting SREBP precursor degradation |
| Sulforaphane | Hepatic Steatosis | 1 | PM | 34722615 | 📋 | Role of the Aryl Hydrocarbon Receptor and Gut Microbiota-Derived Metabolites Indole-3-Acetic Acid in Sulforaphane Alleviates Hepatic Steatosis in Mice |
| Sulforaphane | Hepatitis B | 1 | PM | 38215982 | 📋 | Sulforaphane effectively inhibits HBV by altering Treg/Th17 immune balance and the MIF-macrophages polarizing axis in vitro and in vivo |
| Sulforaphane | Hepatitis C | 1 | PM | 27023634 | 📋 | Sulforaphane Suppresses Hepatitis C Virus Replication by Up-Regulating Heme Oxygenase-1 Expression through PI3K/Nrf2 Pathway |
| Sulforaphane | Hepatotoxicity | 4 | PM | 36650404 | 📋 | Sulforaphane, an Nrf-2 Agonist, Modulates Oxidative Stress and Inflammation in a Rat Model of Cuprizone-Induced Cardiotoxicity and Hepatotoxicity |
| Sulforaphane | Hepatotoxicity | 1 | PM | 32388251 | 📋 | Olanzapine-induced Liver Injury in Mice: Aggravation by High-Fat Diet and Protection With Sulforaphane |
| Sulforaphane | Hepatotoxicity | 2 | PM | 26402917 | 📋 | Sulforaphane Protects the Liver against CdSe Quantum Dot-Induced Cytotoxicity |
| Sulforaphane | Hepatotoxicity | 3 | PM | 21575670 | 📋 | Protective effect of sulforaphane pretreatment against cisplatin-induced liver and mitochondrial oxidant damage in rats |
| Sulforaphane | Liver Cancer | 12 | PM | 36899823 | 📋 | Sulforaphane Potentiates Gemcitabine-Mediated Anti-Cancer Effects against Intrahepatic Cholangiocarcinoma by Inhibiting HDAC Activity |
| Sulforaphane | Liver Cancer | 1 | PM | 32856616 | 📋 | Auranofin Enhances Sulforaphane-Mediated Apoptosis in Hepatocellular Carcinoma Hep3B Cells through Inactivation of the PI3K/Akt Signaling Pathway |
| Sulforaphane | Liver Cancer | 2 | PM | 29866995 | 📋 | Induction of Apoptosis and Cytotoxicity by Isothiocyanate Sulforaphene in Human Hepatocarcinoma HepG2 Cells |
| Sulforaphane | Liver Cancer | 11 | PM | 29747418 | 📋 | Chemopreventive Activities of Sulforaphane and Its Metabolites in Human Hepatoma HepG2 Cells |
| Sulforaphane | Liver Cancer | 5 | PM | 29675806 | 📋 | Comparative Study of Predominant Phytochemical Compounds and Proapoptotic Potential of Broccoli Sprouts and Florets |
| Sulforaphane | Liver Cancer | 3 | PM | 28978924 | 📋 | Sulforaphane exerts anti-angiogenesis effects against hepatocellular carcinoma through inhibition of STAT3/HIF-1α/VEGF signalling |
| Sulforaphane | Liver Cancer | 7 | PM | 21640852 | 📋 | Sulforaphane induces apoptosis in human hepatic cancer cells through inhibition of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase4, mediated by hypoxia inducible factor-1-dependent pathway |
| Sulforaphane | Liver Cancer | 4 | PM | 21278056 | 📋 | Sulforaphane-mediated reduction of aflatoxin B₁-N⁷-guanine in rat liver DNA: impacts of strain and sex |
| Sulforaphane | Liver Cancer | 10 | PM | 20818711 | 📋 | Sulforaphane induces glutathione S-transferase isozymes which detoxify aflatoxin B(1)-8,9-epoxide in AML 12 cells |
| Sulforaphane | Liver Cancer | 6 | PM | 20451318 | 📋 | Sulforaphane decreases viability and telomerase activity in hepatocellular carcinoma Hep3B cells through the reactive oxygen species-dependent pathway |
| Sulforaphane | Liver Cancer | 8 | PM | 17549366 | 📋 | Induction of apoptosis by isothiocyanate sulforaphane in human cervical carcinoma HeLa and hepatocarcinoma HepG2 cells through activation of caspase-3 |
| Sulforaphane | Liver Cancer | 9 | PM | 16452234 | 📋 | Sulforaphane sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-resistant hepatoma cells to TRAIL-induced apoptosis through reactive oxygen species-mediated up-regulation of DR5 |
| Sulforaphane | Liver Damage | 2 | PM | 38721140 | 📋 | Sulforaphane protects against LPS-induced liver injury in mice by antagonizing oxidative stress and apoptosis through AMPK activation |
| Sulforaphane | Liver Damage | 1 | PM | 37513640 | 📋 | Sulforaphane Inhibits Exhaustive Exercise-Induced Liver Injury and Transcriptome-Based Mechanism Analysis |
| Sulforaphane | Liver Damage | 5 | PM | 34174694 | 📋 | Sulforaphane Ameliorates the Liver Injury of Traumatic Hemorrhagic Shock Rats |
| Sulforaphane | Liver Damage | 3 | PM | 20572303 | 📋 | Sulforaphane protects liver injury induced by intestinal ischemia reperfusion through Nrf2-ARE pathway |
| Sulforaphane | Liver Disease | 2 | PM | 37705537 | 📋 | Therapeutic potential of sulforaphane in liver diseases: a review |
| Sulforaphane | Liver Disease | 1 | PM | 20442190 | 📋 | Sulforaphane- and phenethyl isothiocyanate-induced inhibition of aflatoxin B1-mediated genotoxicity in human hepatocytes: role of GSTM1 genotype and CYP3A4 gene expression |
| Sulforaphane | MAFLD | 5 | PM | 36771448 | 📋 | Sulforaphane Ameliorates Nonalcoholic Fatty Liver Disease Induced by High-Fat and High-Fructose Diet via LPS/TLR4 in the Gut-Liver Axis |
| Sulforaphane | MAFLD | 4 | PM | 36448414 | 📋 | The protective effects of sulforaphane on high-fat diet-induced metabolic associated fatty liver disease in mice via mediating the FXR/LXRα pathway |
| Sulforaphane | MAFLD | 3 | PM | 35779187 | 📋 | Modulation of endoplasmic reticulum stress via sulforaphane-mediated AMPK upregulation against nonalcoholic fatty liver disease in rats |
| Sulforaphane | MAFLD | 2 | PM | 35010950 | 📋 | Sulforaphane Attenuates Nonalcoholic Fatty Liver Disease by Inhibiting Hepatic Steatosis and Apoptosis |
| Sulforaphane | MAFLD | 1 | PM | 34654875 | 📋 | Sulforaphane ameliorates non-alcoholic fatty liver disease in mice by promoting FGF21/FGFR1 signaling pathway |
| Sulforaphane | Non-Alcoholic Steatohepatitis | 1 | PM | 26604653 | 📋 | Sulforaphane-rich broccoli sprout extract improves hepatic abnormalities in male subjects |
