| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Lycopene | Alcoholic Liver Disease | 1 | PM | 30603740 | 📋 | Tomato lycopene prevention of alcoholic fatty liver disease and hepatocellular carcinoma development |
| Lycopene | Cholestasis | 1 | PM | 33034714 | 📋 | Protective impact of lycopene on ethinylestradiol-induced cholestasis in rats |
| Lycopene | Cholestasis | 2 | PM | 26422858 | 📋 | Hepatoprotective and antioxidant effects of lycopene in acute cholestasis |
| Lycopene | Cholestasis of Pregnancy | 1 | PM | 33034714 | 📋 | Protective impact of lycopene on ethinylestradiol-induced cholestasis in rats |
| Lycopene | Hepatic Cirrhosis | 2 | PM | 35120355 | 📋 | Lycopene treatment improves intrahepatic fibrosis and attenuates pathological angiogenesis in biliary cirrhotic rats |
| Lycopene | Hepatic Cirrhosis | 1 | PM | 34799306 | 📋 | Protective role of lycopene on blood haematology parameters in liver cirrhosis: Study in rats |
| Lycopene | Hepatic Fibrosis | 2 | PM | 37654036 | 📋 | Lycopene improves autophagy and attenuates carbon tetrachloride-induced hepatic fibrosis in rats |
| Lycopene | Hepatic Fibrosis | 1 | PM | 30889234 | 📋 | Lycopene inhibits hepatic stellate cell activation and modulates cellular lipid storage and signaling |
| Lycopene | Hepatic Ischemia-Reperfusion | 2 | PM | 33987329 | 📋 | Lycopene alleviates hepatic ischemia reperfusion injury via the Nrf2/HO-1 pathway mediated NLRP3 inflammasome inhibition in Kupffer cells |
| Lycopene | Hepatic Ischemia-Reperfusion | 1 | PM | 32813603 | 📋 | Lycopene Alleviates Hepatic Hypoxia/Reoxygenation Injury Through Nrf2/HO-1 Pathway in AML12 Cell |
| Lycopene | Hepatic Steatosis | 1 | PM | 34796193 | 📋 | Translatomics Probes Into the Role of Lycopene on Improving Hepatic Steatosis Induced by High-Fat Diet |
| Lycopene | Hepatitis | 1 | PM | 24028090 | 📋 | Effect of lycopene on oxidative stress induced during D-galactosamine/lipopolysaccharide-sensitized liver injury in rats |
| Lycopene | Hepatotoxicity | 10 | PM | 37485620 | 📋 | Co-occurrence of Mycotoxin-Induced Hepatotoxicity in Mice Inhibited by Lycopene: Mitochondrial Impairment and Early Hepatic Fibrosis |
| Lycopene | Hepatotoxicity | 9 | PM | 37329850 | 📋 | Lycopene attenuates chlorpyrifos-induced hepatotoxicity in rats via activation of Nrf2/HO-1 axis |
| Lycopene | Hepatotoxicity | 6 | PM | 34869769 | 📋 | Lycopene Ameliorates Liver Inflammation and Redox Status in Mice Exposed to Long-Term Cigarette Smoke |
| Lycopene | Hepatotoxicity | 7 | PM | 33965855 | 📋 | Lycopene prevents DEHP-induced hepatic oxidative stress damage by crosstalk between AHR-Nrf2 pathway |
| Lycopene | Hepatotoxicity | 2 | PM | 31378089 | 📋 | The effect of lycopene on hepatotoxicity of aflatoxin B1 in rats |
| Lycopene | Hepatotoxicity | 3 | PM | 30251044 | 📋 | The molecular and biochemical insight view of lycopene in ameliorating tramadol-induced liver toxicity in a rat model: implication of oxidative stress, apoptosis, and MAPK signaling pathways |
| Lycopene | Hepatotoxicity | 1 | PM | 30147835 | 📋 | Lycopene: Hepatoprotective and Antioxidant Effects toward Bisphenol A-Induced Toxicity in Female Wistar Rats |
| Lycopene | Hepatotoxicity | 5 | PM | 30001773 | 📋 | The hepatoprotective effect of lycopene on Con A-induced liver injury in mice |
| Lycopene | Hepatotoxicity | 8 | PM | 28471231 | 📋 | The effects of lycopene on methotrexate-induced liver injury in rats |
| Lycopene | Hepatotoxicity | 4 | PM | 28031152 | 📋 | Lycopene Pretreatment Improves Hepatotoxicity Induced by Acetaminophen in C57BL/6 Mice |
| Lycopene | Hepatotoxicity | 11 | PM | 23572394 | 📋 | Ameliorative effect of lycopene against 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced rat liver microsomal toxicity: an in vitro study |
| Lycopene | Liver Cancer | 3 | PM | 32982734 | 📋 | Anti-Cancer Effects of Lycopene in Animal Models of Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis |
| Lycopene | Liver Cancer | 11 | PM | 30603740 | 📋 | Tomato lycopene prevention of alcoholic fatty liver disease and hepatocellular carcinoma development |
| Lycopene | Liver Cancer | 14 | PM | 28723216 | 📋 | Lycopene Inhibits Metastasis of Human Liver Adenocarcinoma SK-Hep-1 Cells by Downregulation of NADPH Oxidase 4 Protein Expression |
| Lycopene | Liver Cancer | 8 | PM | 27803767 | 📋 | Lycopene modulates cellular proliferation, glycolysis and hepatic ultrastructure during hepatocellular carcinoma |
| Lycopene | Liver Cancer | 5 | PM | 27116542 | 📋 | Tobacco carcinogen induces both lung cancer and non-alcoholic steatohepatitis and hepatocellular carcinomas in ferrets which can be attenuated by lycopene supplementation |
| Lycopene | Liver Cancer | 7 | PM | 26474105 | 📋 | Lycopene Enriched Tomato Extract Inhibits Hypoxia, Angiogenesis, and Metastatic Markers in early Stage N-Nitrosodiethylamine Induced Hepatocellular Carcinoma |
| Lycopene | Liver Cancer | 13 | PM | 24379011 | 📋 | Non-alcoholic steatohepatitis and hepatocellular carcinoma: implications for lycopene intervention |
| Lycopene | Liver Cancer | 12 | PM | 24144777 | 📋 | Lycopene modulates initiation of N-nitrosodiethylamine induced hepatocarcinogenesis: studies on chromosomal abnormalities, membrane fluidity and antioxidant defense system |
| Lycopene | Liver Cancer | 1 | PM | 23583393 | 📋 | Evaluating the effect of lycopene from Lycopersicum esculentum on apoptosis during NDEA induced hepatocarcinogenesis |
| Lycopene | Liver Cancer | 6 | PM | 18287363 | 📋 | Lycopene inhibits experimental metastasis of human hepatoma SK-Hep-1 cells in athymic nude mice |
| Lycopene | Liver Cancer | 10 | PM | 16514180 | 📋 | Inhibitory effects of lycopene on the adhesion, invasion, and migration of SK-Hep1 human hepatoma cells |
| Lycopene | Liver Cancer | 4 | PM | 16410635 | 📋 | The effect of lycopene on cell growth and oxidative DNA damage of Hep3B human hepatoma cells |
| Lycopene | Liver Cancer | 9 | PM | 16140886 | 📋 | Lycopene inhibits cell migration and invasion and upregulates Nm23-H1 in a highly invasive hepatocarcinoma, SK-Hep-1 cells |
| Lycopene | Liver Cancer | 2 | PM | 14769539 | 📋 | Inhibitory Effects of Lutein and Lycopene on Placental Glutathione S-transferase-positive Preneoplastic Lesions and DNA Strand Breakage Induced in Wistar Rats by the Resistant Hepatocyte Model of Hepatocarcinogenesis |
| Lycopene | Liver Damage | 2 | PM | 36318656 | 📋 | Lycopene Alleviates Chronic Stress-Induced Liver Injury by Inhibiting Oxidative Stress-Mediated Endoplasmic Reticulum Stress Pathway Apoptosis in Rats |
| Lycopene | Liver Damage | 1 | PM | 31933889 | 📋 | Lycopene attenuates LPS-induced liver injury by inactivation of NF-κB/COX-2 signaling |
| Lycopene | Liver Disease | 2 | PM | 38398886 | 📋 | Protective Role of Lycopene in Subjects with Liver Disease: NUTRIHEP Study |
| Lycopene | Liver Disease | 1 | PM | 36306869 | 📋 | Promising hepatoprotective effects of lycopene in different liver diseases |
| Lycopene | MAFLD | 7 | PM | 37032779 | 📋 | Lycopene prevents non-alcoholic fatty liver disease through regulating hepatic NF-κB/NLRP3 inflammasome pathway and intestinal microbiota in mice fed with high-fat and high-fructose diet |
| Lycopene | MAFLD | 6 | PM | 35743545 | 📋 | Mediterranean Diet: The Beneficial Effects of Lycopene in Non-Alcoholic Fatty Liver Disease |
| Lycopene | MAFLD | 3 | PM | 33548472 | 📋 | Dietary lycopene attenuates cigarette smoke-promoted nonalcoholic steatohepatitis by preventing suppression of antioxidant enzymes in ferrets |
| Lycopene | MAFLD | 2 | PM | 32574665 | 📋 | Combination of Luteolin and Lycopene Effectively Protect Against the "Two-Hit" in NAFLD Through Sirt1/AMPK Signal Pathway |
| Lycopene | MAFLD | 1 | PM | 32290942 | 📋 | [Effects of Lycopene on Metabolism of Glycolipid and Inflammation in Non-Alcoholic Fatty Liver Disease Rats] |
| Lycopene | MAFLD | 5 | PM | 31387231 | 📋 | Lycopene Modulates Pathophysiological Processes of Non-Alcoholic Fatty Liver Disease in Obese Rats |
| Lycopene | MAFLD | 4 | PM | 28028366 | 📋 | Hepatoprotective and antioxidant effects of lycopene on non-alcoholic fatty liver disease in rat |
| Lycopene | MAFLD | 8 | PM | 23972952 | 📋 | Lipid biomarkers and metabolic effects of lycopene from tomato juice on liver of rats with induced hepatic steatosis |
| Lycopene | Non-Alcoholic Steatohepatitis | 7 | PM | 38544357 | 📋 | Lycopene Alleviates Endoplasmic Reticulum Stress in Steatohepatitis through Inhibition of the ASK1-JNK Signaling Pathway |
| Lycopene | Non-Alcoholic Steatohepatitis | 1 | PM | 32962341 | 📋 | Lycopene prevents DEHP-induced liver lipid metabolism disorder by inhibiting HIF-1α-induced PPARα/PPARγ/FXR/LXR system |
| Lycopene | Non-Alcoholic Steatohepatitis | 5 | PM | 31790829 | 📋 | Lycopene prevents the progression of lipotoxicity-induced nonalcoholic steatohepatitis by decreasing oxidative stress in mice |
| Lycopene | Non-Alcoholic Steatohepatitis | 3 | PM | 31290703 | 📋 | Lycopene and Tomato Sauce Improve Hepatic and Cardiac Cell Biomarkers in Rats |
| Lycopene | Non-Alcoholic Steatohepatitis | 4 | PM | 27116542 | 📋 | Tobacco carcinogen induces both lung cancer and non-alcoholic steatohepatitis and hepatocellular carcinomas in ferrets which can be attenuated by lycopene supplementation |
| Lycopene | Non-Alcoholic Steatohepatitis | 6 | PM | 24379011 | 📋 | Non-alcoholic steatohepatitis and hepatocellular carcinoma: implications for lycopene intervention |
| Lycopene | Non-Alcoholic Steatohepatitis | 2 | PM | 19551842 | 📋 | Dietary lycopene and tomato extract supplementations inhibit nonalcoholic steatohepatitis-promoted hepatocarcinogenesis in rats |
| Lycopene | Obstructive Jaundice | 1 | PM | 23154037 | 📋 | Antioxidant and antigenotoxic effects of lycopene in obstructive jaundice |
| Lycopene | Primary Biliary Cholangitis | 1 | PM | 35120355 | 📋 | Lycopene treatment improves intrahepatic fibrosis and attenuates pathological angiogenesis in biliary cirrhotic rats |
