| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Astragalus Root | Acute Liver Injury | 2 | PM | 36509104 | 📋 | The Anti-inflammatory Effects of Isoflavonoids from Radix Astragali in Hepatoprotective Potential against LPS/D-gal-induced Acute Liver Injury |
| Astragalus Root | Acute Liver Injury | 1 | PM | 35860733 | 📋 | Network Pharmacology-Based Prediction and Pharmacological Validation of Effects of Astragali Radix on Acetaminophen-Induced Liver Injury |
| Astragalus Root | Alcoholic Liver Disease | 2 | PM | 37207880 | 📋 | Astragalus polysaccharide alleviates alcoholic-induced hepatic fibrosis by inhibiting polymerase I and transcript release factor and the TLR4/JNK/NF-κB/MyD88 pathway |
| Astragalus Root | Alcoholic Liver Disease | 1 | PM | 36246879 | 📋 | Seabuckthorn polysaccharide combined with astragalus polysaccharide ameliorate alcoholic fatty liver by regulating intestinal flora |
| Astragalus Root | Biliary Tract Cancer | 1 | PM | 32246704 | 📋 | Anticancer Effect of Radix Astragali on Cholangiocarcinoma In Vitro and Its Mechanism via Network Pharmacology |
| Astragalus Root | Cholestasis | 1 | PM | 28081630 | 📋 | Huang Qi Decoction Prevents BDL-Induced Liver Fibrosis Through Inhibition of Notch Signaling Activation |
| Astragalus Root | Hepatic Fibrosis | 6 | PM | 37400008 | 📋 | Astragalus saponins protect against extrahepatic and intrahepatic cholestatic liver fibrosis models by activation of farnesoid X receptor |
| Astragalus Root | Hepatic Fibrosis | 5 | PM | 35265144 | 📋 | Exploring the Mechanism of Astragalus propinquus Schischkin and Panax Notoginseng (A&P) Compounds in the Treatment of Renal Fibrosis and Chronic Kidney Disease Based on Integrated Network Analysis |
| Astragalus Root | Hepatic Fibrosis | 3 | PM | 33790974 | 📋 | Astragali Radix Contributes to the Inhibition of Liver Fibrosis via High-Mobility Group Box 1-Mediated Inflammatory Signaling Pathway |
| Astragalus Root | Hepatic Fibrosis | 2 | PM | 33551818 | 📋 | Integrating Network Pharmacology and Experimental Validation to Investigate the Effects and Mechanism of Astragalus Flavonoids Against Hepatic Fibrosis |
| Astragalus Root | Hepatic Fibrosis | 4 | PM | 33040784 | 📋 | Effects of Salvia miltiorrhiza and Radix astragali on the TGF-β/Smad/Wnt pathway and the pathological process of liver fibrosis in rats |
| Astragalus Root | Hepatic Fibrosis | 8 | PM | 31467589 | 📋 | Metabolomics combined with network pharmacology exploration reveals the modulatory properties of Astragali Radix extract in the treatment of liver fibrosis |
| Astragalus Root | Hepatic Fibrosis | 11 | PM | 28081630 | 📋 | Huang Qi Decoction Prevents BDL-Induced Liver Fibrosis Through Inhibition of Notch Signaling Activation |
| Astragalus Root | Hepatic Fibrosis | 1 | PM | 27282665 | 📋 | Synergistic anti-liver fibrosis actions of total astragalus saponins and glycyrrhizic acid via TGF-β1/Smads signaling pathway modulation |
| Astragalus Root | Hepatic Fibrosis | 7 | PM | 22927877 | 📋 | The chinese herbal decoction danggui buxue tang inhibits angiogenesis in a rat model of liver fibrosis |
| Astragalus Root | Hepatic Fibrosis | 10 | PM | 22471627 | 📋 | Ingredients of Huangqi decoction slow biliary fibrosis progression by inhibiting the activation of the transforming growth factor-beta signaling pathway |
| Astragalus Root | Hepatic Fibrosis | 9 | PM | 22109673 | 📋 | A standardized extract from Paeonia lactiflora and Astragalus membranaceus attenuates liver fibrosis induced by porcine serum in rats |
| Astragalus Root | Hepatic Steatosis | 1 | PM | 33381046 | 📋 | Astragalus Flavone Ameliorates Atherosclerosis and Hepatic Steatosis Via Inhibiting Lipid-Disorder and Inflammation in apoE -/- Mice |
| Astragalus Root | Hepatic Steatosis | 2 | PM | 32114355 | 📋 | Huang-Qi San improves glucose and lipid metabolism and exerts protective effects against hepatic steatosis in high fat diet-fed rats |
| Astragalus Root | Hepatotoxicity | 5 | PM | 38211994 | 📋 | [Protective effect and mechanism of Astragalus membranaceus and Angelica sinensis compatibility against triptolide-induced hepatotoxicity by regulating Keap1/Nrf2/PGC-1α] |
| Astragalus Root | Hepatotoxicity | 3 | PM | 35561503 | 📋 | Investigating the inter-individual variability of Astragali Radix against cisplatin-induced liver injury via 16S rRNA gene sequencing and LC/MS-based metabolomics |
| Astragalus Root | Hepatotoxicity | 1 | PM | 33834601 | 📋 | Protective Mechanism of Astragalus Polysaccharides against Cantharidin-induced Liver Injury Determined In Vivo by Liquid Chromatography/Mass Spectrometry Metabolomics |
| Astragalus Root | Hepatotoxicity | 2 | PM | 27564381 | 📋 | Hepatoprotective Activity of an Herbal Composition, MAP, a Standardized Blend Comprising Myristica fragrans, Astragalus membranaceus, and Poria cocos |
| Astragalus Root | Hepatotoxicity | 4 | PM | 25415237 | 📋 | Polysaccharides from Angelica and Astragalus exert hepatoprotective effects against carbon-tetrachloride-induced intoxication in mice |
| Astragalus Root | Liver Cancer | 2 | PM | 37100264 | 📋 | A traditional prescription comprising Astragali Radix and Schisandra chinensis Fructus induces apoptosis and protective autophagy in hepatocellular carcinoma cells |
| Astragalus Root | Liver Cancer | 1 | PM | 34663301 | 📋 | Revealing the potential mechanism of Astragalus membranaceus improving prognosis of hepatocellular carcinoma by combining transcriptomics and network pharmacology |
| Astragalus Root | Liver Cancer | 8 | PM | 27279598 | 📋 | Astragalus polysaccharide induces the apoptosis of human hepatocellular carcinoma cells by decreasing the expression of Notch1 |
| Astragalus Root | Liver Cancer | 7 | PM | 24247078 | 📋 | Compound Astragalus and Salvia miltiorrhiza extract suppresses hepatocellular carcinoma progression by inhibiting fibrosis and PAI-1 mRNA transcription |
| Astragalus Root | Liver Cancer | 6 | PM | 24060282 | 📋 | Antitumor and immunomodulatory activity of Astragalus membranaceus polysaccharides in H22 tumor-bearing mice |
| Astragalus Root | Liver Cancer | 5 | PM | 24002667 | 📋 | A standardized extract from Paeonia lactiflora and Astragalus membranaceus induces apoptosis and inhibits the proliferation, migration and invasion of human hepatoma cell lines |
| Astragalus Root | Liver Cancer | 4 | PM | 22784390 | 📋 | Effects of Astragalus polysaccharides on P-glycoprotein efflux pump function and protein expression in H22 hepatoma cells in vitro |
| Astragalus Root | Liver Cancer | 3 | PM | 22490576 | 📋 | Inhibiting effect of Astragalus polysaccharides on the functions of CD4+CD25 highTreg cells in the tumor microenvironment of human hepatocellular carcinoma |
| Astragalus Root | Liver Damage | 1 | PM | 36431990 | 📋 | Angelica sinensis Polysaccharide and Astragalus membranaceus Polysaccharide Accelerate Liver Regeneration by Enhanced Glycolysis via Activation of JAK2/STAT3/HK2 Pathway |
| Astragalus Root | Liver Disease | 1 | PM | 37918281 | 📋 | Radix Astragali decoction improves liver regeneration by upregulating hepatic expression of aquaporin-9 |
| Astragalus Root | MAFLD | 4 | PM | 37967775 | 📋 | Astragalus polysaccharide attenuates nonalcoholic fatty liver disease through THDCA in high-fat diet-fed mice |
| Astragalus Root | MAFLD | 2 | PM | 35726797 | 📋 | Astragalus mongholicus polysaccharides ameliorate hepatic lipid accumulation and inflammation as well as modulate gut microbiota in NAFLD rats |
| Astragalus Root | MAFLD | 3 | PM | 35308224 | 📋 | Pharmacological Effects and Molecular Protective Mechanisms of Astragalus Polysaccharides on Nonalcoholic Fatty Liver Disease |
| Astragalus Root | MAFLD | 1 | PM | 32256659 | 📋 | Protective Effect of a Mixture of Astragalus membranaceus and Lithospermum erythrorhizon Extract against Hepatic Steatosis in High Fat Diet-Induced Nonalcoholic Fatty Liver Disease Mice |
