| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Knotweed | Diabetic Nephropathy | 2 | PM | 26299942 | 📋 | Extract of Rhizoma Polygonum cuspidatum reduces early renal podocyte injury in streptozotocin‑induced diabetic rats and its active compound emodin inhibits methylglyoxal‑mediated glycation of proteins |
| Knotweed | Diabetic Nephropathy | 1 | PM | 25495844 | 📋 | Root of Polygonum cuspidatum extract reduces progression of diabetes-induced mesangial cell dysfunction via inhibition of platelet-derived growth factor-BB (PDGF-BB) and interaction with its receptor in streptozotocin-induced diabetic rats |
| Knotweed | Proteinuria | 1 | PM | 26299942 | 📋 | Extract of Rhizoma Polygonum cuspidatum reduces early renal podocyte injury in streptozotocin‑induced diabetic rats and its active compound emodin inhibits methylglyoxal‑mediated glycation of proteins |
| Knotweed | Septic Acute Kidney Injury | 1 | PM | 37657770 | 📋 | Polygonum cuspidatum Sieb. et Zucc. Extracts improve sepsis-associated acute kidney injury by inhibiting NF-κB-mediated inflammation and pyroptosis |
