| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Ginsenosides | Acute Kidney Injury | 7 | PM | 36580761 | 📋 | Therapeutic propensity of ginsenosides Rg1 and Rg3 in rhabdomyolysis-induced acute kidney injury and renohepatic crosstalk in rats |
| Ginsenosides | Acute Kidney Injury | 4 | PM | 34461812 | 📋 | Protective Effect of 20(R)-Ginsenoside Rg3 Against Cisplatin-Induced Renal Toxicity via PI3K/AKT and NF-[Formula: see text]B Signaling Pathways Based on the Premise of Ensuring Anticancer Effect |
| Ginsenosides | Acute Kidney Injury | 3 | PM | 32932915 | 📋 | Minor Ginsenoside Rg2 and Rh1 Attenuates LPS-Induced Acute Liver and Kidney Damages via Downregulating Activation of TLR4-STAT1 and Inflammatory Cytokine Production in Macrophages |
| Ginsenosides | Acute Kidney Injury | 5 | PM | 31985021 | 📋 | Ginsenoside Protects Against AKI via Activation of HIF‑1α and VEGF‑A in the kidney‑brain Axis |
| Ginsenosides | Acute Kidney Injury | 2 | PM | 31527568 | 📋 | Ginsenoside Rg3 Reduces Epithelial-Mesenchymal Transition Induced by Transforming Growth Factor-β1 by Inactivation of AKT in HMrSV5 Peritoneal Mesothelial Cells |
| Ginsenosides | Acute Kidney Injury | 9 | PM | 24324637 | 📋 | Protective effect of ginsenoside Rb1 against intestinal ischemia-reperfusion induced acute renal injury in mice |
| Ginsenosides | Acute Kidney Injury | 1 | PM | 10803758 | 📋 | The Role of ginsenoside-Rd in Cisplatin-Induced Acute Renal Failure |
| Ginsenosides | Chronic Renal Failure | 3 | PM | 32659400 | 📋 | Ginsenoside Rb1 ameliorates autophagy via the AMPK/mTOR pathway in renal tubular epithelial cells in vitro and in vivo |
| Ginsenosides | Chronic Renal Failure | 1 | PM | 27853891 | 📋 | Impact of Extended Ginsenoside Rb1 on Early Chronic Kidney Disease: A Randomized, Placebo-Controlled Study |
| Ginsenosides | Diabetic Nephropathy | 16 | PM | 38850526 | 📋 | Ginsenoside Rg3 induces mesangial cells proliferation and attenuates apoptosis by miR-216a-5p/MAPK pathway in diabetic kidney disease |
| Ginsenosides | Diabetic Nephropathy | 15 | PM | 36866725 | 📋 | Ginsenoside Rg3 has effects comparable to those of ginsenoside re on diabetic kidney disease prevention in db/db mice by regulating inflammation, fibrosis and PPAR? |
| Ginsenosides | Diabetic Nephropathy | 14 | PM | 36375645 | 📋 | Ginsenoside Rg1 attenuates glomerular fibrosis by inhibiting CD36/TRPC6/NFAT2 signaling in type 2 diabetes mellitus mice |
| Ginsenosides | Diabetic Nephropathy | 13 | PM | 36361652 | 📋 | Ginsenoside Compound K Ameliorates Development of Diabetic Kidney Disease through Inhibiting TLR4 Activation Induced by Microbially Produced Imidazole Propionate |
| Ginsenosides | Diabetic Nephropathy | 12 | PM | 36341813 | 📋 | Beneficial effects of ginsenosides on diabetic nephropathy: A systematical review and meta-analysis of preclinical evidence |
| Ginsenosides | Diabetic Nephropathy | 11 | PM | 35071483 | 📋 | Ginsenoside Rg1 attenuates the inflammation and oxidative stress induced by diabetic nephropathy through regulating the PI3K/AKT/FOXO3 pathway |
| Ginsenosides | Diabetic Nephropathy | 10 | PM | 34811512 | 📋 | Ginsenoside Rb1 alleviates diabetic kidney podocyte injury by inhibiting aldose reductase activity |
| Ginsenosides | Diabetic Nephropathy | 9 | PM | 34308864 | 📋 | [Ginsenoside Rh2 inhibits renal fibrosis and renal cell apoptosis in rats with diabetic nephropathy by downregulating discoid domain receptor 1] |
| Ginsenosides | Diabetic Nephropathy | 8 | PM | 34049473 | 📋 | Ginsenoside Rh1 Improves Type 2 Diabetic Nephropathy through AMPK/PI3K/Akt-Mediated Inflammation and Apoptosis Signaling Pathway |
| Ginsenosides | Diabetic Nephropathy | 7 | PM | 33445772 | 📋 | Pectin-Lyase-Modified Ginseng Extract and Ginsenoside Rd Inhibits High Glucose-Induced ROS Production in Mesangial Cells and Prevents Renal Dysfunction in db/db Mice |
| Ginsenosides | Diabetic Nephropathy | 6 | PM | 33133213 | 📋 | Ginsenoside Rg1 Alleviates Podocyte Injury Induced by Hyperlipidemia via Targeting the mTOR/NF- κ B/NLRP3 Axis |
| Ginsenosides | Diabetic Nephropathy | 5 | PM | 33091499 | 📋 | Alleviative effects of 20(R)-Rg3 on HFD/STZ-induced diabetic nephropathy via MAPK/NF-κB signaling pathways in C57BL/6 mice |
| Ginsenosides | Diabetic Nephropathy | 3 | PM | 32156650 | 📋 | Protective Effect of Ginsenoside Rg5 Against Kidney Injury via Inhibition of NLRP3 Inflammasome Activation and the MAPK Signaling Pathway in High-Fat diet/streptozotocin-induced Diabetic Mice |
| Ginsenosides | Diabetic Nephropathy | 1 | PM | 30425453 | 📋 | Combination of Ginsenoside Rg1 and Astragaloside IV Reduces Oxidative Stress and Inhibits TGF-β1/Smads Signaling Cascade on Renal Fibrosis in Rats With Diabetic Nephropathy |
| Ginsenosides | Diabetic Nephropathy | 2 | PM | 30107367 | 📋 | Protective Effect of Ginsenoside Metabolite Compound K Against Diabetic Nephropathy by Inhibiting NLRP3 Inflammasome Activation and NF-κB/p38 Signaling Pathway in High-Fat diet/streptozotocin-induced Diabetic Mice |
| Ginsenosides | Diabetic Nephropathy | 4 | PM | 27279428 | 📋 | Genomic Expression Profiling and Bioinformatics Analysis on Diabetic Nephrology With Ginsenoside Rg3 |
| Ginsenosides | Kidney Cancer | 1 | PM | 38583003 | 📋 | Ginsenoside Rh4 Facilitates the Sensitivity of Renal Cell Carcinoma to Ferroptosis via the NRF2 Pathway |
| Ginsenosides | Kidney Damage | 3 | PM | 38373586 | 📋 | Ginsenoside Rb1 alleviates 3-MCPD-induced renal cell pyroptosis by activating mitophagy |
| Ginsenosides | Kidney Damage | 2 | PM | 37252277 | 📋 | Ginsenoside Rb3 ameliorates podocyte injury under hyperlipidemic conditions via PPARδ- or SIRT6-mediated suppression of inflammation and oxidative stress |
| Ginsenosides | Kidney Damage | 1 | PM | 35421784 | 📋 | Ginsenoside Rg1 attenuates LPS-induced chronic renal injury by inhibiting NOX4-NLRP3 signaling in mice |
| Ginsenosides | Kidney Disease | 1 | PM | 36814491 | 📋 | Renal function protection and the mechanism of ginsenosides: Current progress and future perspectives |
| Ginsenosides | Kidney Fibrosis | 7 | PM | 38683298 | 📋 | Integrative informatics analysis identifies that ginsenoside Re improves renal fibrosis through regulation of autophagy |
| Ginsenosides | Kidney Fibrosis | 6 | PM | 37017270 | 📋 | Ginsenoside Rg1 treatment alleviates renal fibrosis by inhibiting the NOX4-MAPK pathway in T2DM mice |
| Ginsenosides | Kidney Fibrosis | 5 | PM | 35873571 | 📋 | Ginsenoside Rb1 Ameliorated Bavachin-Induced Renal Fibrosis via Suppressing Bip/eIF2α/CHOP Signaling-Mediated EMT |
| Ginsenosides | Kidney Fibrosis | 4 | PM | 35421784 | 📋 | Ginsenoside Rg1 attenuates LPS-induced chronic renal injury by inhibiting NOX4-NLRP3 signaling in mice |
| Ginsenosides | Kidney Fibrosis | 3 | PM | 34308864 | 📋 | [Ginsenoside Rh2 inhibits renal fibrosis and renal cell apoptosis in rats with diabetic nephropathy by downregulating discoid domain receptor 1] |
| Ginsenosides | Kidney Fibrosis | 2 | PM | 32659400 | 📋 | Ginsenoside Rb1 ameliorates autophagy via the AMPK/mTOR pathway in renal tubular epithelial cells in vitro and in vivo |
| Ginsenosides | Kidney Fibrosis | 1 | PM | 29607931 | 📋 | Ginsenoside-Rg1 Protects Against Renal Fibrosis by Regulating the Klotho/TGF-β1/Smad Signaling Pathway in Rats With Obstructive Nephropathy |
| Ginsenosides | Nephrotoxicity | 1 | PM | 35873571 | 📋 | Ginsenoside Rb1 Ameliorated Bavachin-Induced Renal Fibrosis via Suppressing Bip/eIF2α/CHOP Signaling-Mediated EMT |
| Ginsenosides | Nephrotoxicity | 2 | PM | 29348725 | 📋 | Protective effect of ginsenoside Rb1 against tacrolimus-induced apoptosis in renal proximal tubular LLC-PK1 cells |
| Ginsenosides | Proteinuria | 1 | PM | 33445772 | 📋 | Pectin-Lyase-Modified Ginseng Extract and Ginsenoside Rd Inhibits High Glucose-Induced ROS Production in Mesangial Cells and Prevents Renal Dysfunction in db/db Mice |
| Ginsenosides | Renal Cell Carcinoma | 3 | PM | 36396667 | 📋 | Ginsenoside Rh2 sensitizes the anti-cancer effects of sunitinib by inducing cell cycle arrest in renal cell carcinoma |
| Ginsenosides | Renal Cell Carcinoma | 2 | PM | 36264186 | 📋 | Ginsenoside Rg3 inhibits renal cell carcinoma cell migration, invasion, colony formation, and tube formation and enhances apoptosis through promoting the DNA demethylation and histone acetylation |
| Ginsenosides | Renal Cell Carcinoma | 1 | PM | 33649829 | 📋 | Ginsenoside compound K exerts antitumour effects in renal cell carcinoma via regulation of ROS and lncRNA THOR |
| Ginsenosides | Renal Ischemia-Reperfusion | 1 | PM | 32198879 | 📋 | Notoginsenoside R1 Suppresses Inflammatory Signaling and Rescues Renal Ischemia-Reperfusion Injury in Experimental Rats |
| Ginsenosides | Septic Acute Kidney Injury | 3 | PM | 38563049 | 📋 | Nephroprotective effect of Ginsenoside Rg1 in lipopolysaccharide-induced sepsis in mice through the SIRT1/NF-κB signaling |
| Ginsenosides | Septic Acute Kidney Injury | 1 | PM | 37287288 | 📋 | Ginsenoside Rg1 Suppresses Ferroptosis of Renal Tubular Epithelial Cells in Sepsis-induced Acute Kidney Injury via the FSP1-CoQ10-NAD(P)H Pathway |
| Ginsenosides | Septic Acute Kidney Injury | 2 | PM | 35774015 | 📋 | Ginsenoside Rg1 ameliorates sepsis-induced acute kidney injury by inhibiting ferroptosis in renal tubular epithelial cells |
