| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Berberine | Acute Kidney Injury | 6 | PM | 38705399 | 📋 | Berberine alleviated contrast-induced acute kidney injury by mitophagy-mediated NLRP3 inflammasome inactivation in a mice model |
| Berberine | Acute Kidney Injury | 5 | PM | 37922559 | 📋 | Berberine ameliorates contrast-induced acute kidney injury by regulating HDAC4-FoxO3a axis-induced autophagy: In vivo and in vitro |
| Berberine | Acute Kidney Injury | 4 | PM | 33329722 | 📋 | Integrated Analysis of m6A Methylome in Cisplatin-Induced Acute Kidney Injury and Berberine Alleviation in Mouse |
| Berberine | Acute Kidney Injury | 3 | PM | 32944532 | 📋 | Berberine alleviates cisplatin-induced acute kidney injury by regulating mitophagy via PINK 1/Parkin pathway |
| Berberine | Acute Kidney Injury | 1 | PM | 31603884 | 📋 | Reno-protective Effect of Berberine |
| Berberine | Acute Kidney Injury | 2 | PM | 31334048 | 📋 | Synergistic Effect of Berberine and Pentoxifylline in Attenuation of Acute Kidney Injury |
| Berberine | Chronic Renal Failure | 2 | PM | 37139409 | 📋 | Berberine ameliorates chronic kidney disease through inhibiting the production of gut-derived uremic toxins in the gut microbiota |
| Berberine | Chronic Renal Failure | 1 | PM | 33179098 | 📋 | Berberine alleviates palmitic acid‑induced podocyte apoptosis by reducing reactive oxygen species‑mediated endoplasmic reticulum stress |
| Berberine | Diabetic Nephropathy | 23 | PM | 37977063 | 📋 | Exploring the molecular mechanism of berberine for treating diabetic nephropathy based on network pharmacology |
| Berberine | Diabetic Nephropathy | 17 | PM | 36861878 | 📋 | Treatment of berberine alleviates diabetic nephropathy by reducing iron overload and inhibiting oxidative stress |
| Berberine | Diabetic Nephropathy | 16 | PM | 36195307 | 📋 | Protective Effect of Berberine in Diabetic Nephropathy: A Systematic Review and Meta-Analysis Revealing the Mechanism of Action |
| Berberine | Diabetic Nephropathy | 15 | PM | 35971382 | 📋 | Berberine Reduces Renal Cell Pyroptosis in Golden Hamsters with Diabetic Nephropathy through the Nrf2-NLRP3-Caspase-1-GSDMD Pathway |
| Berberine | Diabetic Nephropathy | 14 | PM | 35618411 | 📋 | Berberine protects diabetic nephropathy by suppressing epithelial-to-mesenchymal transition involving the inactivation of the NLRP3 inflammasome |
| Berberine | Diabetic Nephropathy | 13 | PM | 35069186 | 📋 | Berberine Reduces Lipid Accumulation by Promoting Fatty Acid Oxidation in Renal Tubular Epithelial Cells of the Diabetic Kidney |
| Berberine | Diabetic Nephropathy | 12 | PM | 35001506 | 📋 | Berberine regulates mesangial cell proliferation and cell cycle to attenuate diabetic nephropathy through the PI3K/Akt/AS160/GLUT1 signalling pathway |
| Berberine | Diabetic Nephropathy | 11 | PM | 34773184 | 📋 | Berberine Improves the Protective Effects of Metformin on Diabetic Nephropathy in db/db Mice through Trib1-dependent Inhibiting Inflammation |
| Berberine | Diabetic Nephropathy | 10 | PM | 34526965 | 📋 | Berberine Acts on C/EBPβ/lncRNA Gas5/miR-18a-5p Loop to Decrease the Mitochondrial ROS Generation in HK-2 Cells |
| Berberine | Diabetic Nephropathy | 9 | PM | 32001218 | 📋 | Highly Bioavailable Berberine Formulation Ameliorates Diabetic Nephropathy Through the Inhibition of Glomerular Mesangial Matrix Expansion and the Activation of Autophagy |
| Berberine | Diabetic Nephropathy | 1 | PM | 31360147 | 📋 | Ameliorative Effect of Berberine on Neonatally Induced Type 2 Diabetic Neuropathy via Modulation of BDNF, IGF-1, PPAR-γ, and AMPK Expressions |
| Berberine | Diabetic Nephropathy | 8 | PM | 31337260 | 📋 | Berberine Reduces Neuroglia Activation and Inflammation in Streptozotocin-Induced Diabetic Mice |
| Berberine | Diabetic Nephropathy | 5 | PM | 31336024 | 📋 | Berberine Ameliorates Renal Impairment and Inhibits Podocyte Dysfunction by Targeting the Phosphatidylinositol 3-kinase-protein Kinase B Pathway in Diabetic Rats |
| Berberine | Diabetic Nephropathy | 2 | PM | 29604956 | 📋 | Berberine Ameliorates Diabetic Nephropathy by Inhibiting TLR4/NF-κB Pathway |
| Berberine | Diabetic Nephropathy | 3 | PM | 29121795 | 📋 | Berberine Ameliorates Diabetic Neuropathy: TRPV1 Modulation by PKC Pathway |
| Berberine | Diabetic Nephropathy | 7 | PM | 28087385 | 📋 | Berberine Exerts Renoprotective Effects by Regulating the AGEs-RAGE Signaling Pathway in Mesangial Cells During Diabetic Nephropathy |
| Berberine | Diabetic Nephropathy | 4 | PM | 27529235 | 📋 | Protective Effects of Berberine on Renal Injury in Streptozotocin (STZ)-Induced Diabetic Mice |
| Berberine | Diabetic Nephropathy | 6 | PM | 27098986 | 📋 | Renoprotective Effect of Berberine via Regulating the PGE2 -EP1-Gαq-Ca(2+) Signalling Pathway in Glomerular Mesangial Cells of Diabetic Rats |
| Berberine | Diabetic Nephropathy | 22 | PM | 25912800 | 📋 | Berberine as a promising anti-diabetic nephropathy drug: An analysis of its effects and mechanisms |
| Berberine | Diabetic Nephropathy | 19 | PM | 23896433 | 📋 | Berberine ameliorates experimental diabetes-induced renal inflammation and fibronectin by inhibiting the activation of RhoA/ROCK signaling |
| Berberine | Diabetic Nephropathy | 18 | PM | 23266672 | 📋 | Berberine ameliorates renal injury by regulating G proteins-AC- cAMP signaling in diabetic rats with nephropathy |
| Berberine | Diabetic Nephropathy | 21 | PM | 22483555 | 📋 | Ameliorative effect of berberine on renal damage in rats with diabetes induced by high-fat diet and streptozotocin |
| Berberine | Diabetic Nephropathy | 20 | PM | 22368864 | 📋 | [Effect of berberine on expression of transforming growth factor-beta1 and type IV collagen proteins in mesangial cells of diabetic rats with nephropathy] |
| Berberine | Glomerulosclerosis | 1 | PM | 31734944 | 📋 | Berberine Protects Against Diabetic Kidney Disease via Promoting PGC-1α-regulated Mitochondrial Energy Homeostasis |
| Berberine | Kidney Cancer | 1 | PM | 37033923 | 📋 | Identification of berberine as a potential therapeutic strategy for kidney clear cell carcinoma and COVID-19 based on analysis of large-scale datasets |
| Berberine | Kidney Cancer | 2 | PM | 24002362 | 📋 | Berberine inhibits Wilms' tumor cell progression through upregulation of Wilms' tumor gene on the X chromosome |
| Berberine | Kidney Damage | 3 | PM | 31746359 | 📋 | Berberine Ameliorates Lipopolysaccharide‑induced Inflammatory Responses in Mouse Inner Medullary Collecting duct‑3 Cells by Downregulation of NF‑κB Pathway |
| Berberine | Kidney Damage | 4 | PM | 26823767 | 📋 | Protective Effects of Berberine on High Fat-Induced Kidney Damage by Increasing Serum Adiponectin and Promoting Insulin Sensitivity |
| Berberine | Kidney Disease | 4 | PM | 36814494 | 📋 | Advances of berberine against metabolic syndrome-associated kidney disease: Regarding effect and mechanism |
| Berberine | Kidney Disease | 3 | PM | 35718235 | 📋 | Protective effects of berberine on various kidney diseases: Emphasis on the promising effects and the underlined molecular mechanisms |
| Berberine | Kidney Disease | 2 | PM | 31734944 | 📋 | Berberine Protects Against Diabetic Kidney Disease via Promoting PGC-1α-regulated Mitochondrial Energy Homeostasis |
| Berberine | Kidney Disease | 1 | PM | 21823461 | 📋 | [Effects and Mechanism of Berberine on the Hypertensive Renal Injury Rats Induced by Enriched High Fat-Salt-Fructose Diet] |
| Berberine | Kidney Fibrosis | 3 | PM | 37811696 | 📋 | Berberine ameliorates renal interstitial inflammation and fibrosis in mice with unilateral ureteral obstruction |
| Berberine | Kidney Fibrosis | 2 | PM | 34371291 | 📋 | The protective impact of berberine against doxorubicin-induced nephrotoxicity in rats |
| Berberine | Kidney Fibrosis | 1 | PM | 27529235 | 📋 | Protective Effects of Berberine on Renal Injury in Streptozotocin (STZ)-Induced Diabetic Mice |
| Berberine | Nephrotoxicity | 12 | PM | 38327393 | 📋 | Berberine alleviates chlorpyrifos-induced nephrotoxicity in rats via modulation of Nrf2/HO-1 axis |
| Berberine | Nephrotoxicity | 11 | PM | 37909687 | 📋 | Berberine alleviates contrast-induced nephropathy by activating Akt/Foxo3a/Nrf2 signalling pathway |
| Berberine | Nephrotoxicity | 8 | PM | 36221996 | 📋 | The protection afforded by Berberine against chemotherapy-mediated nephropathy in rats involves regulation of the antioxidant axis |
| Berberine | Nephrotoxicity | 7 | PM | 36208663 | 📋 | Insights into the role of P2X7R/DUSP6/ERK1/2 and SIRT2/MDM2 signaling in the nephroprotective effect of berberine against cisplatin-induced renal fibrosis in rats |
| Berberine | Nephrotoxicity | 6 | PM | 35427583 | 📋 | Berberis integerrima hydro-alcoholic root extract ant its constituent berberine protect against cisplatin-induced nephro- and hepato-toxicity |
| Berberine | Nephrotoxicity | 1 | PM | 34994821 | 📋 | Protective effects of berberine as a natural antioxidant and anti-inflammatory agent against nephrotoxicity induced by cyclophosphamide in mice |
| Berberine | Nephrotoxicity | 2 | PM | 34371291 | 📋 | The protective impact of berberine against doxorubicin-induced nephrotoxicity in rats |
| Berberine | Nephrotoxicity | 3 | PM | 34349501 | 📋 | Effect of Berberine on Hyperuricemia and Kidney Injury: A Network Pharmacology Analysis and Experimental Validation in a Mouse Model |
| Berberine | Nephrotoxicity | 4 | PM | 33959014 | 📋 | Anti-Hyperuricemic and Nephroprotective Effects of Dihydroberberine in Potassium Oxonate- and Hypoxanthine-Induced Hyperuricemic Mice |
| Berberine | Nephrotoxicity | 5 | PM | 32410067 | 📋 | Pretreatment With Berberine Protects Against Cisplatin-Induced Renal Injury in Male Wistar Rats |
| Berberine | Nephrotoxicity | 10 | PM | 29204934 | 📋 | Preventive use of berberine in inhibition of lead-induced renal injury in rats |
| Berberine | Nephrotoxicity | 9 | PM | 24025684 | 📋 | Berberine exerts nephroprotective effect against cisplatin-induced kidney damage through inhibition of oxidative/nitrosative stress, inflammation, autophagy and apoptosis |
| Berberine | Polycystic Kidney Disease | 1 | PM | 24184483 | 📋 | Berberine slows cell growth in autosomal dominant polycystic kidney disease cells |
| Berberine | Renal Cell Carcinoma | 2 | PM | 37217616 | 📋 | Berberine inhibits the progression of renal cell carcinoma cells by regulating reactive oxygen species generation and inducing DNA damage |
| Berberine | Renal Cell Carcinoma | 1 | PM | 31874443 | 📋 | Berberine Associated Photodynamic Therapy Promotes Autophagy and Apoptosis via ROS Generation in Renal Carcinoma Cells |
| Berberine | Renal Ischemia-Reperfusion | 4 | PM | 38291383 | 📋 | Berberine alleviates ischemia reperfusion injury induced AKI by regulation of intestinal microbiota and reducing intestinal inflammation |
| Berberine | Renal Ischemia-Reperfusion | 1 | PM | 30186432 | 📋 | Therapeutic Effect of Berberine on Renal Ischemia-Reperfusion Injury in Rats and Its Effect on Bax and Bcl-2 |
| Berberine | Renal Ischemia-Reperfusion | 2 | PM | 29680964 | 📋 | Berberine Protects Renal Tubular Cells Against Hypoxia/Reoxygenation Injury via the Sirt1/p53 Pathway |
| Berberine | Renal Ischemia-Reperfusion | 3 | PM | 29260413 | 📋 | Berberine protects HK-2 cells from hypoxia/reoxygenation induced apoptosis via inhibiting SPHK1 expression |
| Berberine | Uremia | 1 | PM | 27506986 | 📋 | Berberine Reduces Uremia-Associated Intestinal Mucosal Barrier Damage |
