| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| EGCG | Acute Kidney Injury | 4 | PM | 37847436 | 📋 | Alleviation effects of epigallocatechin-3-gallate against acute kidney injury following severe burns |
| EGCG | Acute Kidney Injury | 3 | PM | 37092712 | 📋 | Epigallocatechin-3-gallate in combination with corticosteroids mitigates heat stress-induced acute kidney injury through modulating heat shock protein 70 and toll-like receptor 4-dependent pathways |
| EGCG | Acute Kidney Injury | 2 | PM | 36028100 | 📋 | Rhabdomyolysis-induced acute kidney injury and concomitant apoptosis induction via ROS-mediated ER stress is efficaciously counteracted by epigallocatechin gallate |
| EGCG | Acute Kidney Injury | 1 | PM | 26675556 | 📋 | Green Tea Polyphenol Prevents Diabetic Rats From Acute Kidney Injury After Cardiopulmonary Bypass |
| EGCG | Acute Liver Injury | 1 | PM | 36548773 | 📋 | Epigallocatechin Gallate and Glutathione Attenuate Aflatoxin B1-Induced Acute Liver Injury in Ducklings via Mitochondria-Mediated Apoptosis and the Nrf2 Signalling Pathway |
| EGCG | Acute Lung Injury | 6 | PM | 38662666 | 📋 | Epigallocatechin gallate regulates the myeloid-specific transcription factor PU.1 in macrophages |
| EGCG | Acute Lung Injury | 5 | PM | 36139034 | 📋 | Preventive Effect of Epigallocatechin Gallate, the Main Component of Green Tea, on Acute Lung Injury Caused by Air Pollutants |
| EGCG | Acute Lung Injury | 4 | PM | 35547130 | 📋 | Epigallocatechin-3-Gallate Ameliorates Acute Lung Damage by Inhibiting Quorum-Sensing-Related Virulence Factors of Pseudomonas aeruginosa |
| EGCG | Acute Lung Injury | 3 | PM | 34040072 | 📋 | EGCG promotes PRKCA expression to alleviate LPS-induced acute lung injury and inflammatory response |
| EGCG | Acute Lung Injury | 2 | PM | 34018522 | 📋 | Epigallocatechin-3-gallate attenuates acute pancreatitis induced lung injury by targeting mitochondrial reactive oxygen species triggered NLRP3 inflammasome activation |
| EGCG | Acute Lung Injury | 1 | PM | 32575718 | 📋 | Epigallocatechin-3-Gallate (EGCG), an Active Compound of Green Tea Attenuates Acute Lung Injury Regulating Macrophage Polarization and Krüpple-Like-Factor 4 (KLF4) Expression |
| EGCG | Brain Injury | 1 | PM | 22692966 | 📋 | Green Tea epigallocatechin-3-gallate (EGCG) Promotes Neural Progenitor Cell Proliferation and Sonic Hedgehog Pathway Activation During Adult Hippocampal Neurogenesis |
| EGCG | Brain Injury | 2 | PM | 20013823 | 📋 | (-)-Epigallocatechin-3-gallate increases cell proliferation and neuroblasts in the subgranular zone of the dentate gyrus in adult mice |
| EGCG | Burn Injury | 2 | PM | 37847436 | 📋 | Alleviation effects of epigallocatechin-3-gallate against acute kidney injury following severe burns |
| EGCG | Burn Injury | 1 | PM | 27574685 | 📋 | The Evidence for Natural Therapeutics as Potential Anti-Scarring Agents in Burn-Related Scarring |
| EGCG | Diabetic Ulcers and Sores | 3 | PM | 38179734 | 📋 | EGCG Restores Keratinocyte Autophagy to Promote Diabetic Wound Healing through the AMPK/ULK1 Pathway |
| EGCG | Diabetic Ulcers and Sores | 2 | PM | 38140774 | 📋 | Epigallocatechin-3-gallate promotes wound healing response in diabetic mice by activating keratinocytes and promoting re-epithelialization |
| EGCG | Diabetic Ulcers and Sores | 1 | PM | 19128267 | 📋 | Enhanced wound healing by an epigallocatechin gallate-incorporated collagen sponge in diabetic mice |
| EGCG | Intestinal Injury | 1 | PM | 34730149 | 📋 | (-)-Epigallocatechin-3-gallate mitigates cyclophosphamide-induced intestinal injury by modulating the tight junctions, inflammation and dysbiosis in mice |
| EGCG | Ischemia-Reperfusion Injuries | 1 | PM | 31816476 | 📋 | Protective Effect of Epigallocatechin Gallate in Ischemia-Reperfusion Injury of Rat Skeletal Muscle |
| EGCG | Jellyfish Sting | 2 | PM | 37104221 | 📋 | Protective Effects of Epigallocatechin-3-gallate (EGCG) against the Jellyfish Nemopilema nomurai Envenoming |
| EGCG | Jellyfish Sting | 1 | PM | 33122740 | 📋 | Protective effect of epigallocatechin-3-gallate (EGCG) on toxic metalloproteinases-mediated skin damage induced by Scyphozoan jellyfish envenomation |
| EGCG | Light-Induced Retinal Damage | 1 | PM | 35039875 | 📋 | Epigallocatechin gallate enhances human lens epithelial cell survival after UVB irradiation via the mitochondrial signaling pathway |
| EGCG | Light-Induced Retinal Damage | 2 | PM | 23916613 | 📋 | Epigallocatechin-gallate (EGCG) regulates autophagy in human retinal pigment epithelial cells: a potential role for reducing UVB light-induced retinal damage |
| EGCG | Liver Damage | 2 | PM | 36113316 | 📋 | Epigallocatechin-3-gallate ameliorates liver injury secondary to Pseudomonas aeruginosa pneumonia |
| EGCG | Liver Damage | 1 | PM | 32570121 | 📋 | Epigallocatechin-3-gallate Protects Immunity and Liver Drug-Metabolism Function in Mice Loaded With Restraint Stress |
| EGCG | Lung Injury | 2 | PM | 31003767 | 📋 | Effects of epigallocatechin-3-gallate on the HMGB1/RAGE Pathway in PM 2.5-exposed Asthmatic Rats |
| EGCG | Lung Injury | 3 | PM | 28198717 | 📋 | Mitochondrial DNA-Induced Inflammatory Responses and Lung Injury in Thermal Injury Rat Model: Protective Effect of Epigallocatechin Gallate |
| EGCG | Lung Injury | 1 | PM | 27020813 | 📋 | Epigallocatechin Gallate Attenuates Cardiopulmonary Bypass-Associated Lung Injury |
| EGCG | Myocardial Injury | 2 | PM | 37875765 | 📋 | Protective effects of epigallocatechin-3-gallate counteracting the chronic hypobaric hypoxia-induced myocardial injury in plain-grown rats at high altitude |
| EGCG | Myocardial Injury | 3 | PM | 31582423 | 📋 | Epicatechin-3-Gallate Signaling and Protection Against Cardiac Ischemia/Reperfusion Injury |
| EGCG | Myocardial Injury | 1 | PM | 24251870 | 📋 | Epigallocatechin-3-gallate-mediated cardioprotection by Akt/GSK-3β/caveolin signalling in H9c2 rat cardiomyoblasts |
| EGCG | Neuronal Damage | 7 | PM | 38427657 | 📋 | Epigallocatechin gallate improves neuronal damage in animal model of ischemic stroke and glutamate-exposed neurons via modulation of hippocalcin expression |
| EGCG | Neuronal Damage | 5 | PM | 37107343 | 📋 | EGCG Attenuates CA1 Neuronal Death by Regulating GPx1, NF-κB S536 Phosphorylation and Mitochondrial Dynamics in the Rat Hippocampus following Status Epilepticus |
| EGCG | Neuronal Damage | 3 | PM | 36598312 | 📋 | Epigallocatechin-3-gallate and resveratrol attenuate hydrogen peroxide induced damage in neuronal cells |
| EGCG | Neuronal Damage | 4 | PM | 35000557 | 📋 | Neuroprotective effects of catechins in an experimental Parkinson's disease model and SK-N-AS cells: evaluation of cell viability, anti-inflammatory and anti-apoptotic effects |
| EGCG | Neuronal Damage | 2 | PM | 34214383 | 📋 | Green tea and its active compound epigallocathechin-3-gallate (EGCG) inhibit neuronal apoptosis in a middle cerebral artery occlusion (MCAO) model |
| EGCG | Neuronal Damage | 1 | PM | 34214296 | 📋 | The effect of Camellia sinensis (green tea) with its active compound EGCG on neuronal cell necroptosis in Rattus norvegicus middle cerebral artery occlusion (MCAO) model |
| EGCG | Neuronal Damage | 6 | PM | 24421757 | 📋 | Neuroprotective effects of resveratrol and epigallocatechin gallate polyphenols are mediated by the activation of protein kinase C gamma |
| EGCG | Peripheral Nerve Injury | 2 | PM | 26037187 | 📋 | Biochemical and Histopathological Effects of Catechin on Experimental Peripheral Nerve Injuries |
| EGCG | Radiation Damage - Cell Phone | 1 | PM | 20807176 | 📋 | Mobile Phone Radiation-Induced Free Radical Damage in the Liver Is Inhibited by the Antioxidants N-acetyl Cysteine and Epigallocatechin-Gallate |
| EGCG | Radiation Damage - Gamma Rays | 1 | PM | 20707208 | 📋 | [Protective Activity of Different Concentration of Tea Polyphenols and Its Major Compound EGCG Against Whole Body Irradiation-Induced Injury in Mice] |
| EGCG | Radiation Dermatitis | 2 | PM | 37620508 | 📋 | Efficacy and safety of epigallocatechin-3-gallate in treatment acute severe dermatitis in patients with cancer receiving radiotherapy: a phase I clinical trial |
| EGCG | Radiation Dermatitis | 1 | PM | 35648426 | 📋 | Efficacy of Epigallocatechin-3-Gallate in Preventing Dermatitis in Patients With Breast Cancer Receiving Postoperative Radiotherapy: A Double-Blind, Placebo-Controlled, Phase 2 Randomized Clinical Trial |
| EGCG | Radiation Induced Damage | 3 | PM | 35480105 | 📋 | (-)-Epigallocatechin-3-Gallate (EGCG) Modulates the Composition of the Gut Microbiota to Protect Against Radiation-Induced Intestinal Injury in Mice |
| EGCG | Radiation Induced Damage | 2 | PM | 33808935 | 📋 | Epigallocatechin-3-Gallate Protects Pro-Acinar Epithelia Against Salivary Gland Radiation Injury |
| EGCG | Radiation Induced Damage | 1 | PM | 33069855 | 📋 | Green tea derivative (-)-epigallocatechin-3-gallate (EGCG) confers protection against ionizing radiation-induced intestinal epithelial cell death both in vitro and in vivo |
| EGCG | Sciatic Nerve Injury | 1 | PM | 28777065 | 📋 | Possible role of antioxidative capacity of (-)-epigallocatechin-3-gallate treatment in morphological and neurobehavioral recovery after sciatic nerve crush injury |
| EGCG | Sciatic Nerve Injury | 2 | PM | 25025489 | 📋 | (-)-Epigallocatechin-3-gallate modulates spinal cord neuronal degeneration by enhancing growth-associated protein 43, B-cell lymphoma 2, and decreasing B-cell lymphoma 2-associated x protein expression after sciatic nerve crush injury |
| EGCG | Skin Photo Damage | 4 | PM | 38304421 | 📋 | Photoprotective Effects of Epigallocatechin Gallate on Ultraviolet-Induced Zebrafish and Human Skin Fibroblasts Cells |
| EGCG | Skin Photo Damage | 3 | PM | 37863121 | 📋 | Collagen-EGCG Combination Synergistically Prevents UVB-induced Skin Photoaging in Nude Mice |
| EGCG | Skin Photo Damage | 2 | PM | 36704608 | 📋 | (-)-Epigallocatechin-3-Gallate Protects Human Skin Fibroblasts from Ultraviolet a Induced Photoaging |
| EGCG | Skin Photo Damage | 1 | PM | 18226437 | 📋 | (-)Epigallocatechin gallate hampers collagen destruction and collagenase activation in ultraviolet-B-irradiated human dermal fibroblasts: involvement of mitogen-activated protein kinase |
| EGCG | Spinal Cord Injury | 9 | PM | 37499782 | 📋 | Hyperbaric oxygen in combination with epigallocatechin-3-gallate synergistically enhance recovery from spinal cord injury in rats |
| EGCG | Spinal Cord Injury | 4 | PM | 36829922 | 📋 | The Role of Green Tea Catechin Epigallocatechin Gallate (EGCG) and Mammalian Target of Rapamycin (mTOR) Inhibitor PP242 (Torkinib) in the Treatment of Spinal Cord Injury |
| EGCG | Spinal Cord Injury | 3 | PM | 33335755 | 📋 | EGCG modulates PKD1 and ferroptosis to promote recovery in ST rats |
| EGCG | Spinal Cord Injury | 8 | PM | 31809244 | 📋 | Assessment of the neuroprotective effects of (-)-epigallocatechin-3-gallate on spinal cord ischemia-reperfusion injury in rats |
| EGCG | Spinal Cord Injury | 7 | PM | 28899730 | 📋 | A green tea polyphenol epigallocatechin-3-gallate enhances neuroregeneration after spinal cord injury by altering levels of inflammatory cytokines |
| EGCG | Spinal Cord Injury | 1 | PM | 25314656 | 📋 | Polyphenols From Green Tea Prevent Antineuritogenic Action of Nogo-A via 67-kDa Laminin Receptor and Hydrogen Peroxide |
| EGCG | Spinal Cord Injury | 6 | PM | 24071567 | 📋 | (-)-Epigallocatechin-3-gallate (EGCG) modulates neurological function when intravenously infused in acute and, chronically injured spinal cord of adult rats |
| EGCG | Spinal Cord Injury | 5 | PM | 23831998 | 📋 | Anti-edema effect of epigallocatechin gallate on spinal cord injury in rats |
| EGCG | Spinal Cord Injury | 2 | PM | 19815005 | 📋 | Effects of epigallocatechin gallate on tissue protection and functional recovery after contusive spinal cord injury in rats |
| EGCG | Testicular Torsion | 1 | PM | 23946684 | 📋 | (-)-Epigallocatechin-3-gallate Modulates the Differential Expression of Survivin Splice Variants and Protects Spermatogenesis During Testicular Torsion |
| EGCG | Traumatic Brain Injury | 1 | PM | 32062732 | 📋 | (-)-Epigallocatechin-3-gallate provides neuroprotection via AMPK activation against traumatic brain injury in a mouse model |
| EGCG | Wound Healing | 7 | PM | 34771213 | 📋 | Epigallocatechin Gallate: The Emerging Wound Healing Potential of Multifunctional Biomaterials for Future Precision Medicine Treatment Strategies |
| EGCG | Wound Healing | 6 | PM | 34684703 | 📋 | Beneficial Effects of Green Tea EGCG on Skin Wound Healing: A Comprehensive Review |
| EGCG | Wound Healing | 5 | PM | 33917842 | 📋 | Pre-Emptive Priming of Human Skin Improves Cutaneous Scarring and Is Superior to Immediate and Delayed Topical Anti-Scarring Treatment Post-Wounding: A Double-Blind Randomised Placebo-Controlled Clinical Trial |
| EGCG | Wound Healing | 1 | PM | 30822414 | 📋 | A Double-Blind, Randomized Trial Shows the Role of Zonal Priming and Direct Topical Application of Epigallocatechin-3-Gallate in the Modulation of Cutaneous Scarring in Human Skin |
| EGCG | Wound Healing | 2 | PM | 30070931 | 📋 | Wound Healing Can Be Improved by (-)-Epigallocatechin Gallate Through Targeting Notch in Streptozotocin-Induced Diabetic Mice |
| EGCG | Wound Healing | 4 | PM | 19128267 | 📋 | Enhanced wound healing by an epigallocatechin gallate-incorporated collagen sponge in diabetic mice |
