| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Berberine | Acute Kidney Injury | 6 | PM | 38705399 | 📋 | Berberine alleviated contrast-induced acute kidney injury by mitophagy-mediated NLRP3 inflammasome inactivation in a mice model |
| Berberine | Acute Kidney Injury | 5 | PM | 37922559 | 📋 | Berberine ameliorates contrast-induced acute kidney injury by regulating HDAC4-FoxO3a axis-induced autophagy: In vivo and in vitro |
| Berberine | Acute Kidney Injury | 4 | PM | 33329722 | 📋 | Integrated Analysis of m6A Methylome in Cisplatin-Induced Acute Kidney Injury and Berberine Alleviation in Mouse |
| Berberine | Acute Kidney Injury | 3 | PM | 32944532 | 📋 | Berberine alleviates cisplatin-induced acute kidney injury by regulating mitophagy via PINK 1/Parkin pathway |
| Berberine | Acute Kidney Injury | 1 | PM | 31603884 | 📋 | Reno-protective Effect of Berberine |
| Berberine | Acute Kidney Injury | 2 | PM | 31334048 | 📋 | Synergistic Effect of Berberine and Pentoxifylline in Attenuation of Acute Kidney Injury |
| Berberine | Acute Liver Injury | 1 | PM | 31432116 | 📋 | Berberine Ameliorates CCl4‑induced Liver Injury in Rats Through Regulation of the Nrf2‑Keap1‑ARE and p53 Signaling Pathways |
| Berberine | Acute Lung Injury | 2 | PM | 35284463 | 📋 | Berberine Ameliorates Inflammation in Acute Lung Injury via NF-κB/Nlrp3 Signaling Pathway |
| Berberine | Acute Lung Injury | 1 | PM | 30346043 | 📋 | Berberine Ameliorates Lipopolysaccharide-Induced Acute Lung Injury via the PERK-mediated Nrf2/HO-1 Signaling Axis |
| Berberine | Acute Lung Injury | 5 | PM | 23605560 | 📋 | Berberine attenuates cigarette smoke-induced acute lung inflammation |
| Berberine | Brain Injury | 2 | PM | 29399112 | 📋 | Neuroprotective Effect of Berberine Against Learning and Memory Deficits in Diffuse Axonal Injury |
| Berberine | Burn Injury | 1 | PM | 38108311 | 📋 | Berberine decreases S100B generation to regulate gut vascular barrier permeability in mice with burn injury |
| Berberine | Diabetic Ulcers and Sores | 2 | PM | 35430394 | 📋 | Huangbai liniment and berberine promoted wound healing in high-fat diet/Streptozotocin-induced diabetic rats |
| Berberine | Diabetic Ulcers and Sores | 1 | PM | 33491733 | 📋 | Berberine accelerated wound healing by restoring TrxR1/JNK in diabetes |
| Berberine | Endothelial Injury | 1 | PM | 35003308 | 📋 | Berberine Protects against TNF- α-Induced Injury of Human Umbilical Vein Endothelial Cells via the AMPK/NF- κ B/YY1 Signaling Pathway |
| Berberine | Intestinal Injury | 4 | PM | 38474567 | 📋 | LC-MS-Based Metabolomics Reveals the Mechanism of Protection of Berberine against Indomethacin-Induced Gastric Injury in Rats |
| Berberine | Intestinal Injury | 2 | PM | 35158228 | 📋 | Berberine suppresses cecal ligation and puncture induced intestinal injury by enhancing Treg cell function |
| Berberine | Intestinal Injury | 1 | PM | 34174323 | 📋 | Berberine and/or zinc protect against methotrexate-induced intestinal damage: Role of GSK-3β/NRF2 and JAK1/STAT-3 signaling pathways |
| Berberine | Intestinal Injury | 3 | PM | 21963898 | 📋 | Berberine protects against lipopolysaccharide-induced intestinal injury in mice via alpha 2 adrenoceptor-independent mechanisms |
| Berberine | Kidney Damage | 3 | PM | 31746359 | 📋 | Berberine Ameliorates Lipopolysaccharide‑induced Inflammatory Responses in Mouse Inner Medullary Collecting duct‑3 Cells by Downregulation of NF‑κB Pathway |
| Berberine | Kidney Damage | 4 | PM | 26823767 | 📋 | Protective Effects of Berberine on High Fat-Induced Kidney Damage by Increasing Serum Adiponectin and Promoting Insulin Sensitivity |
| Berberine | Light-Induced Retinal Damage | 2 | PM | 38489005 | 📋 | Purinergic P2X7 receptor involves in anti-retinal photodamage effects of berberine |
| Berberine | Light-Induced Retinal Damage | 1 | PM | 26475979 | 📋 | Berberine Protects Against Light-Induced Photoreceptor Degeneration in the Mouse Retina |
| Berberine | Liver Damage | 1 | PM | 35436630 | 📋 | Hydrochloride Berberine ameliorates alcohol-induced liver injury by regulating inflammation and lipid metabolism |
| Berberine | Liver Damage | 6 | PM | 35078575 | 📋 | [Berberine hydrochloride attenuates liver injury induced by acute hypoxic exposure by inhibiting TNF-α/caspase-8/caspase-3 signaling pathway] |
| Berberine | Myocardial Injury | 6 | PM | 38731953 | 📋 | Berberine Improves Cancer-Derived Myocardial Impairment in Experimental Cachexia Models by Targeting High-Mobility Group Box-1 |
| Berberine | Myocardial Injury | 3 | PM | 35495613 | 📋 | Berberine attenuates sepsis-induced cardiac dysfunction by upregulating the Akt/eNOS pathway in mice |
| Berberine | Myocardial Injury | 2 | PM | 33484149 | 📋 | Supplemental Berberine in a High-Fat Diet Reduces Adiposity and Cardiac Dysfunction in Offspring of Mouse Dams with Gestational Diabetes Mellitus |
| Berberine | Myocardial Injury | 1 | PM | 30021340 | 📋 | Berberine Promoted Myocardial Protection of Postoperative Patients Through Regulating Myocardial Autophagy |
| Berberine | Myocardial Injury | 5 | PM | 28627660 | 📋 | Inhibition of Autophagy by Berberine Enhances the Survival of H9C2 Myocytes Following Hypoxia |
| Berberine | Myocardial Injury | 4 | PM | 26846272 | 📋 | Berberine Pretreatment Confers Cardioprotection Against Ischemia-Reperfusion Injury in a Rat Model of Type 2 Diabetes |
| Berberine | Neuronal Damage | 8 | PM | 37506403 | 📋 | Berberine ameliorates iron levels and ferroptosis in the brain of 3 × Tg-AD mice |
| Berberine | Neuronal Damage | 4 | PM | 34342315 | 📋 | Protective effects of berberine against MPTP-induced dopaminergic neuron injury through promoting autophagy in mice |
| Berberine | Neuronal Damage | 3 | PM | 34137676 | 📋 | Effects of Berberine on Diabetes and Cognitive Impairment in an Animal Model: The Mechanisms of Action |
| Berberine | Neuronal Damage | 2 | PM | 33995012 | 📋 | Berberine Attenuates Cerebral Ischemia-Reperfusion Injury Induced Neuronal Apoptosis by Down-Regulating the CNPY2 Signaling Pathway |
| Berberine | Neuronal Damage | 1 | PM | 33925781 | 📋 | Effect of Berberine Isolated from Barberry Species by Centrifugal Partition Chromatography on Memory and the Expression of Parvalbumin in the Mouse Hippocampus Proper |
| Berberine | Neuronal Damage | 6 | PM | 29228691 | 📋 | Berberine attenuated pro-inflammatory factors and protect against neuronal damage via triggering oligodendrocyte autophagy in spinal cord injury |
| Berberine | Neuronal Damage | 5 | PM | 23540404 | 📋 | The protective effect of berberine against neuronal damage by inhibiting matrix metalloproteinase-9 and laminin degradation in experimental autoimmune encephalomyelitis |
| Berberine | Neuronal Damage | 7 | PM | 22052603 | 📋 | Effects of berberine on hippocampal neuronal damage and matrix metalloproteinase-9 activity following transient global cerebral ischemia |
| Berberine | Peripheral Nerve Injury | 2 | PM | 38570276 | 📋 | Berberine inhibits NLRP3 inflammasome activation and proinflammatory macrophage M1 polarization to accelerate peripheral nerve regeneration |
| Berberine | Peripheral Nerve Injury | 1 | PM | 33034886 | 📋 | Improving sciatic nerve regeneration by using alginate/chitosan hydrogel containing berberine |
| Berberine | Radiation Induced Damage | 1 | PM | 19757213 | 📋 | Berberine Inhibits Acute Radiation Intestinal Syndrome in Human With Abdomen Radiotherapy |
| Berberine | Spinal Cord Injury | 2 | PM | 36178590 | 📋 | High-Throughput Screening Assay Identifies Berberine and Mubritinib as Neuroprotection Drugs for Spinal Cord Injury via Blood-Spinal Cord Barrier Protection |
| Berberine | Spinal Cord Injury | 1 | PM | 35121005 | 📋 | Investigation of the effects of berberine on bortezomib-induced sciatic nerve and spinal cord damage in rats through pathways involved in oxidative stress and neuro-inflammation |
| Berberine | Spinal Cord Injury | 3 | PM | 29228691 | 📋 | Berberine attenuated pro-inflammatory factors and protect against neuronal damage via triggering oligodendrocyte autophagy in spinal cord injury |
| Berberine | Tendon Injury | 1 | PM | 35343961 | 📋 | Alleviation of Diabetic Tendon Injury via Activation of Tendon Fibroblasts Autophagy under Berberine Treatment |
| Berberine | Tendon Injury | 2 | PM | 33204294 | 📋 | Effects and Mechanism of Berberine on the Dexamethasone-Induced Injury of Human Tendon Cells |
| Berberine | Traumatic Brain Injury | 1 | PM | 30027364 | 📋 | Berberine Protects Secondary Injury in Mice With Traumatic Brain Injury Through Anti-oxidative and Anti-inflammatory Modulation |
| Berberine | Traumatic Brain Injury | 2 | PM | 29512719 | 📋 | Neuroprotective Effect of Berberine Agonist Against Impairment of Learning and Memory Skills in Severe Traumatic Brain Injury via Sirt1/p38 MAPK Expression |
| Berberine | Wound Healing | 2 | PM | 33892030 | 📋 | Berberine carried gelatin/sodium alginate hydrogels with antibacterial and EDTA-induced detachment performances |
| Berberine | Wound Healing | 1 | PM | 33073124 | 📋 | A Facile Synthesis of Self-Catalytic Hydrogel Films and Their Application as a Wound Dressing Material Coupled with Natural Active Compounds |
