| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| Cannabidiol | Acute Lymphoblastic Leukemia | 3 | PM | 33379175 | 📋 | Phenolic Compounds Cannabidiol, Curcumin and Quercetin Cause Mitochondrial Dysfunction and Suppress Acute Lymphoblastic Leukemia Cells |
| Cannabidiol | Acute Lymphoblastic Leukemia | 2 | PM | 31611561 | 📋 | Cannabidiol Directly Targets Mitochondria and Disturbs Calcium Homeostasis in Acute Lymphoblastic Leukemia |
| Cannabidiol | Acute Lymphoblastic Leukemia | 1 | PM | 12091357 | 📋 | Targeting CB2 Cannabinoid Receptors as a Novel Therapy to Treat Malignant Lymphoblastic Disease |
| Cannabidiol | Acute Myeloid Leukemia | 1 | PM | 28560402 | 📋 | Anticancer Effects of Phytocannabinoids Used With Chemotherapy in Leukaemia Cells Can Be Improved by Altering the Sequence of Their Administration |
| Cannabidiol | Acute Myeloid Leukemia | 2 | PM | 14692532 | 📋 | Gamma-irradiation Enhances Apoptosis Induced by Cannabidiol, a Non-Psychotropic Cannabinoid, in Cultured HL-60 Myeloblastic Leukemia Cells |
| Cannabidiol | Allergic Asthma | 1 | PM | 30481497 | 📋 | Cannabidiol Reduces Airway Inflammation and Fibrosis in Experimental Allergic Asthma |
| Cannabidiol | Anaphylaxis | 1 | PM | 38059783 | 📋 | Cannabidiol Inhibits IgE-Mediated Mast Cell Degranulation and Anaphylaxis in Mice |
| Cannabidiol | Autoimmune Disease | 6 | PM | 36834537 | 📋 | Effects of Cannabidiol on Innate Immunity: Experimental Evidence and Clinical Relevance |
| Cannabidiol | Autoimmune Disease | 5 | PM | 27256343 | 📋 | Pathways and Gene Networks Mediating the Regulatory Effects of Cannabidiol, a Nonpsychoactive Cannabinoid, in Autoimmune T Cells |
| Cannabidiol | Autoimmune Disease | 1 | PM | 26772776 | 📋 | Cannabidiol Limits T Cell-Mediated Chronic Autoimmune Myocarditis: Implications to Autoimmune Disorders and Organ Transplantation |
| Cannabidiol | Autoimmune Disease | 2 | PM | 24841204 | 📋 | Histone Modifications Are Associated With Δ9-tetrahydrocannabinol-mediated Alterations in Antigen-Specific T Cell Responses |
| Cannabidiol | Autoimmune Disease | 4 | PM | 19457575 | 📋 | Cannabinoid-induced Apoptosis in Immune Cells as a Pathway to Immunosuppression |
| Cannabidiol | Autoimmune Disease | 3 | PM | 12130702 | 📋 | Delta(9)-tetrahydrocannabinol-induced Apoptosis in the Thymus and Spleen as a Mechanism of Immunosuppression in Vitro and in Vivo |
| Cannabidiol | Burkitt's Lymphoma | 1 | PM | 31587870 | 📋 | The Evaluation of Cannabidiol's Effect on the Immunotherapy of Burkitt Lymphoma |
| Cannabidiol | Chronic Inflammation | 5 | PM | 37891916 | 📋 | Protective Actions of Cannabidiol on Aging-Related Inflammation, Oxidative Stress and Apoptosis Alterations in Liver and Lung of Long Evans Rats |
| Cannabidiol | Chronic Inflammation | 4 | PM | 34997430 | 📋 | Anti-inflammatory potential of cannabidiol (CBD) on combination of caecal slurry, LPS, and E. coli-induced systemic inflammatory response syndrome (SIRS) in Sprague Dawley Rats |
| Cannabidiol | Chronic Inflammation | 1 | PM | 32933892 | 📋 | Natural cannabinoids suppress the cytokine storm in sepsis-like in vitro model |
| Cannabidiol | Chronic Inflammation | 2 | PM | 30596146 | 📋 | The Anti-Inflammatory Properties of Terpenoids From Cannabis |
| Cannabidiol | Chronic Inflammation | 3 | PM | 27435265 | 📋 | Cannabinoids, Inflammation, and Fibrosis |
| Cannabidiol | Chronic Myeloid Leukemia | 2 | PM | 38268604 | 📋 | A label free chemoproteomic-based platform to disclose cannabidiol molecular mechanism of action on chronic myelogenous leukemia cancer cells |
| Cannabidiol | Chronic Myeloid Leukemia | 1 | PM | 34971020 | 📋 | The effects of cannabidiol via TRPV2 channel in chronic myeloid leukemia cells and its combination with imatinib |
| Cannabidiol | Cytokine Storm Syndrome | 2 | PM | 32933892 | 📋 | Natural cannabinoids suppress the cytokine storm in sepsis-like in vitro model |
| Cannabidiol | Cytokine Storm Syndrome | 1 | PM | 32923657 | 📋 | Cannabidiol Modulates Cytokine Storm in Acute Respiratory Distress Syndrome Induced by Simulated Viral Infection Using Synthetic RNA |
| Cannabidiol | HIV/AIDS | 3 | PM | 37147420 | 📋 | Anti-inflammatory effects of CBD in human microglial cell line infected with HIV-1 |
| Cannabidiol | HIV/AIDS | 1 | PM | 29471387 | 📋 | Heavy Cannabis Use Associated With Reduction in Activated and Inflammatory Immune Cell Frequencies in Antiretroviral Therapy-Treated Human Immunodeficiency Virus-Infected Individuals |
| Cannabidiol | HIV/AIDS | 2 | PM | 25900076 | 📋 | Modulation of HIVGP120 Antigen-Specific Immune Responses In Vivo by Δ9-Tetrahydrocannabinol |
| Cannabidiol | Immune System Regulation | 4 | PM | 37836465 | 📋 | Eight Weeks of Daily Cannabidiol Supplementation Improves Sleep Quality and Immune Cell Cytotoxicity |
| Cannabidiol | Immune System Regulation | 2 | PM | 12446015 | 📋 | Delta 9-Tetrahydrocannabinol Regulates Th1/Th2 Cytokine Balance in Activated Human T Cells |
| Cannabidiol | Immune System Regulation | 1 | PM | 12130702 | 📋 | Delta(9)-tetrahydrocannabinol-induced Apoptosis in the Thymus and Spleen as a Mechanism of Immunosuppression in Vitro and in Vivo |
| Cannabidiol | Immune System Regulation | 3 | PM | 12052046 | 📋 | Endocannabinoids in the Immune System and Cancer |
| Cannabidiol | Inflammation | 44 | PM | 38245915 | 📋 | The mechanism by which cannabidiol (CBD) suppresses TNF-α secretion involves inappropriate localization of TNF-α converting enzyme (TACE) |
| Cannabidiol | Inflammation | 36 | PM | 36881078 | 📋 | Anti-inflammatory Effect of a Combination of Cannabidiol and Morinda citrifolia Extract on Lipopolysaccharide-stimulated RAW264 Macrophages |
| Cannabidiol | Inflammation | 30 | PM | 36755953 | 📋 | Cannabidiol regulates apoptosis and autophagy in inflammation and cancer: A review |
| Cannabidiol | Inflammation | 35 | PM | 35443806 | 📋 | Effects of Cannabidiol Interactions with CYP2R1, CYP27B1, CYP24A1, and Vitamin D 3 Receptors on Spatial Memory, Pain, Inflammation, and Aging in Vitamin D 3 Deficiency Diet-Induced Rats |
| Cannabidiol | Inflammation | 15 | PM | 34082108 | 📋 | The anti-inflammatory effects of cannabidiol and cannabigerol alone, and in combination |
| Cannabidiol | Inflammation | 11 | PM | 33584697 | 📋 | Cannabinoids as Key Regulators of Inflammasome Signaling: A Current Perspective |
| Cannabidiol | Inflammation | 7 | PM | 32933892 | 📋 | Natural cannabinoids suppress the cytokine storm in sepsis-like in vitro model |
| Cannabidiol | Inflammation | 33 | PM | 32374168 | 📋 | Inhibitory Effect of Cannabidiol on the Activation of NLRP3 Inflammasome Is Associated With Its Modulation of the P2X7 Receptor in Human Monocytes |
| Cannabidiol | Inflammation | 21 | PM | 31881765 | 📋 | Antioxidative and Anti-Inflammatory Properties of Cannabidiol |
| Cannabidiol | Inflammation | 32 | PM | 31437494 | 📋 | Cannabidiol Differentially Regulates Basal and LPS-induced Inflammatory Responses in Macrophages, Lung Epithelial Cells, and Fibroblasts |
| Cannabidiol | Inflammation | 42 | PM | 30627539 | 📋 | Cannabis sativa L. And Nonpsychoactive Cannabinoids: Their Chemistry and Role Against Oxidative Stress, Inflammation, and Cancer |
| Cannabidiol | Inflammation | 22 | PM | 30610735 | 📋 | Anti-inflammatory Mechanisms of Cannabinoids: An Immunometabolic Perspective |
| Cannabidiol | Inflammation | 12 | PM | 30596146 | 📋 | The Anti-Inflammatory Properties of Terpenoids From Cannabis |
| Cannabidiol | Inflammation | 28 | PM | 30542832 | 📋 | Cannabinoids: Potential Role in Inflammatory and Neoplastic Skin Diseases |
| Cannabidiol | Inflammation | 8 | PM | 29561958 | 📋 | Maternal Administration of Cannabidiol Promotes an Anti-Inflammatory Effect on the Intestinal Wall in a Gastroschisis Rat Model |
| Cannabidiol | Inflammation | 29 | PM | 29082318 | 📋 | Cannabis Roots: A Traditional Therapy With Future Potential for Treating Inflammation and Pain |
| Cannabidiol | Inflammation | 1 | PM | 28174520 | 📋 | Modulation of Human Peripheral Blood Mononuclear Cell Signaling by Medicinal Cannabinoids |
| Cannabidiol | Inflammation | 40 | PM | 27215129 | 📋 | Anti-inflammatory and Antioxidant Effects of a Combination of Cannabidiol and Moringin in LPS-stimulated Macrophages |
| Cannabidiol | Inflammation | 19 | PM | 26883973 | 📋 | β-caryophyllene, a Dietary Cannabinoid, Complexed With β-cyclodextrin Produced Anti-Hyperalgesic Effect Involving the Inhibition of Fos Expression in Superficial Dorsal Horn |
| Cannabidiol | Inflammation | 43 | PM | 26824325 | 📋 | Up-regulation of Immunomodulatory Effects of Mouse Bone-Marrow Derived Mesenchymal Stem Cells by Tetrahydrocannabinol Pre-Treatment Involving Cannabinoid Receptor CB2 |
| Cannabidiol | Inflammation | 17 | PM | 26517407 | 📋 | Transdermal Cannabidiol Reduces Inflammation and Pain-Related Behaviours in a Rat Model of Arthritis |
| Cannabidiol | Inflammation | 20 | PM | 25703248 | 📋 | Cannabidiol (CBD) and Its Analogs: A Review of Their Effects on Inflammation |
| Cannabidiol | Inflammation | 13 | PM | 25445433 | 📋 | Regulation of Inflammation and Proliferation of Human Bladder Carcinoma Cells by type-1 and type-2 Cannabinoid Receptors |
| Cannabidiol | Inflammation | 18 | PM | 23889474 | 📋 | Anti-inflammatory Activity of Topical THC in DNFB-mediated Mouse Allergic Contact Dermatitis Independent of CB1 and CB2 Receptors |
| Cannabidiol | Inflammation | 38 | PM | 23851307 | 📋 | Cannabidiol Provides Long-Lasting Protection Against the Deleterious Effects of Inflammation in a Viral Model of Multiple Sclerosis: A Role for A2A Receptors |
| Cannabidiol | Inflammation | 23 | PM | 23373571 | 📋 | The Cannabinoid TRPA1 Agonist Cannabichromene Inhibits Nitric Oxide Production in Macrophages and Ameliorates Murine Colitis |
| Cannabidiol | Inflammation | 6 | PM | 22860209 | 📋 | Sativex-like Combination of Phytocannabinoids Is Neuroprotective in Malonate-Lesioned Rats, an Inflammatory Model of Huntington's Disease: Role of CB1 and CB2 Receptors |
| Cannabidiol | Inflammation | 34 | PM | 22739983 | 📋 | Cannabidiol Protects Oligodendrocyte Progenitor Cells From Inflammation-Induced Apoptosis by Attenuating Endoplasmic Reticulum Stress |
| Cannabidiol | Inflammation | 4 | PM | 22300105 | 📋 | Inhibitory Effect of Cannabichromene, a Major Non-Psychotropic Cannabinoid Extracted From Cannabis Sativa, on Inflammation-Induced Hypermotility in Mice |
| Cannabidiol | Inflammation | 2 | PM | 22163000 | 📋 | Cannabidiol Reduces Intestinal Inflammation Through the Control of Neuroimmune Axis |
| Cannabidiol | Inflammation | 27 | PM | 21532172 | 📋 | Evaluation of the Cyclooxygenase Inhibiting Effects of Six Major Cannabinoids Isolated From Cannabis Sativa |
| Cannabidiol | Inflammation | 26 | PM | 21175579 | 📋 | Effects of Cannabinoids and Cannabinoid-Enriched Cannabis Extracts on TRP Channels and Endocannabinoid Metabolic Enzymes |
| Cannabidiol | Inflammation | 3 | PM | 20619971 | 📋 | Pharmacological Evaluation of the Natural Constituent of Cannabis Sativa, Cannabichromene and Its Modulation by Δ(9)-tetrahydrocannabinol |
| Cannabidiol | Inflammation | 25 | PM | 20191092 | 📋 | Cannabinoids as Novel Anti-Inflammatory Drugs |
| Cannabidiol | Inflammation | 31 | PM | 19910459 | 📋 | Cannabinoids Delta(9)-tetrahydrocannabinol and Cannabidiol Differentially Inhibit the Lipopolysaccharide-Activated NF-kappaB and interferon-beta/STAT Proinflammatory Pathways in BV-2 Microglial Cells |
| Cannabidiol | Inflammation | 39 | PM | 19204413 | 📋 | The Nonpsychotropic Cannabinoid Cannabidiol Modulates and Directly Activates alpha-1 and alpha-1-Beta Glycine Receptor Function |
| Cannabidiol | Inflammation | 41 | PM | 18615144 | 📋 | Role of the Cannabinoid System in Pain Control and Therapeutic Implications for the Management of Acute and Chronic Pain Episodes |
| Cannabidiol | Inflammation | 24 | PM | 17339608 | 📋 | Cannabidiol, Unlike Synthetic Cannabinoids, Triggers Activation of RBL-2H3 Mast Cells |
| Cannabidiol | Inflammation | 37 | PM | 17245363 | 📋 | Cannabidiol Displays Unexpectedly High Potency as an Antagonist of CB1 and CB2 Receptor Agonists in Vitro |
| Cannabidiol | Inflammation | 14 | PM | 17157290 | 📋 | The Non-Psychoactive Cannabis Constituent Cannabidiol Is an Orally Effective Therapeutic Agent in Rat Chronic Inflammatory and Neuropathic Pain |
| Cannabidiol | Inflammation | 10 | PM | 15815632 | 📋 | Low Dose Oral Cannabinoid Therapy Reduces Progression of Atherosclerosis in Mice |
| Cannabidiol | Inflammation | 16 | PM | 15313881 | 📋 | Vanilloid TRPV1 Receptor Mediates the Antihyperalgesic Effect of the Nonpsychoactive Cannabinoid, Cannabidiol, in a Rat Model of Acute Inflammation |
| Cannabidiol | Inflammation | 9 | PM | 14963641 | 📋 | Oral Anti-Inflammatory Activity of Cannabidiol, a Non-Psychoactive Constituent of Cannabis, in Acute Carrageenan-Induced Inflammation in the Rat Paw |
| Cannabidiol | Inflammation | 5 | PM | 14644587 | 📋 | Cannabidiol-transdermal Delivery and Anti-Inflammatory Effect in a Murine Model |
| Cannabidiol | Leukemia | 1 | PM | 37837474 | 📋 | The potential protective and therapeutic effects of cannabidiol oil on experimental Leukemia induced by DMBA in male rats |
| Cannabidiol | Leukemia | 8 | PM | 16908594 | 📋 | Delta9-tetrahydrocannabinol-induced Apoptosis in Jurkat Leukemia T Cells Is Regulated by Translocation of Bad to Mitochondria |
| Cannabidiol | Leukemia | 6 | PM | 16754784 | 📋 | Cannabidiol-induced Apoptosis in Human Leukemia Cells: A Novel Role of Cannabidiol in the Regulation of p22phox and Nox4 Expression |
| Cannabidiol | Leukemia | 4 | PM | 16624285 | 📋 | The CB2 Cannabinoid Receptor Signals Apoptosis via Ceramide-Dependent Activation of the Mitochondrial Intrinsic Pathway |
| Cannabidiol | Leukemia | 3 | PM | 16458258 | 📋 | The Effects of Cannabinoids on P-glycoprotein Transport and Expression in Multidrug Resistant Cells |
| Cannabidiol | Leukemia | 7 | PM | 16139274 | 📋 | p38 MAPK Is Involved in CB2 Receptor-Induced Apoptosis of Human Leukaemia Cells |
| Cannabidiol | Leukemia | 5 | PM | 15978942 | 📋 | Targeting Cannabinoid Receptors to Treat Leukemia: Role of Cross-Talk Between Extrinsic and Intrinsic Pathways in Delta9-tetrahydrocannabinol (THC)-induced Apoptosis of Jurkat Cells |
| Cannabidiol | Leukemia | 9 | PM | 15454482 | 📋 | Cannabis-induced Cytotoxicity in Leukemic Cell Lines: The Role of the Cannabinoid Receptors and the MAPK Pathway |
| Cannabidiol | Lymphoma | 2 | PM | 32284791 | 📋 | Synergistic Cytotoxic Activity of Cannabinoids From cannabis sativa Against Cutaneous T-cell Lymphoma (CTCL) in-vitro and ex-vivo |
| Cannabidiol | Lymphoma | 1 | PM | 16936228 | 📋 | Cannabinoid Receptor-Mediated Apoptosis Induced by R(+)-methanandamide and Win55,212-2 Is Associated With Ceramide Accumulation and p38 Activation in Mantle Cell Lymphoma |
| Cannabidiol | Lymphoma | 3 | PM | 16337199 | 📋 | Cannabinoid Receptor Ligands Mediate Growth Inhibition and Cell Death in Mantle Cell Lymphoma |
| Cannabidiol | Mastocytosis | 1 | PM | 36831056 | 📋 | The Effectiveness and Safety of Pharmaceutical-Grade Cannabidiol in the Treatment of Mastocytosis-Associated Pain: A Pilot Study |
| Cannabidiol | Multiple Myeloma | 2 | PM | 27769052 | 📋 | Cannabinoids Synergize With Carfilzomib, Reducing Multiple Myeloma Cells Viability and Migration |
| Cannabidiol | Multiple Myeloma | 1 | PM | 24293211 | 📋 | The Effects of Cannabidiol and Its Synergism With Bortezomib in Multiple Myeloma Cell Lines. A Role for Transient Receptor Potential Vanilloid type-2 |
| Cannabidiol | Sepsis | 1 | PM | 20561509 | 📋 | Treatment With Cannabidiol Reverses Oxidative Stress Parameters, Cognitive Impairment and Mortality in Rats Submitted to Sepsis by Cecal Ligation and Puncture |
