| Substance | Condition | Seq | Src | PMID | Dtl | Title |
| EGCG | Alzheimer's Disease | 32 | PM | 38275516 | 📋 | Epigallocatechin-3-Gallate and Genistein for Decreasing Gut Dysbiosis, Inhibiting Inflammasomes, and Aiding Autophagy in Alzheimer's Disease |
| EGCG | Alzheimer's Disease | 31 | PM | 38095777 | 📋 | Epigallocatechin Gallate Modulates Microglia Phenotype to Suppress Pro-inflammatory Signalling Cues and Inhibit Phagocytosis |
| EGCG | Alzheimer's Disease | 30 | PM | 37507998 | 📋 | Alzheimer's Disease and Green Tea: Epigallocatechin-3-Gallate as a Modulator of Inflammation and Oxidative Stress |
| EGCG | Alzheimer's Disease | 24 | PM | 36591187 | 📋 | Structural Remodeling Mechanism of the Toxic Amyloid Fibrillary Mediated by Epigallocatechin-3-gallate |
| EGCG | Alzheimer's Disease | 23 | PM | 36078067 | 📋 | A Combination Therapy of Urolithin A+EGCG Has Stronger Protective Effects than Single Drug Urolithin A in a Humanized Amyloid Beta Knockin Mice for Late-Onset Alzheimer's Disease |
| EGCG | Alzheimer's Disease | 22 | PM | 35721940 | 📋 | Inhibition Mechanisms of (-)-Epigallocatechin-3-gallate and Genistein on Amyloid-beta 42 Peptide of Alzheimer's Disease via Molecular Simulations |
| EGCG | Alzheimer's Disease | 21 | PM | 35327563 | 📋 | Epigallocatechin-3-Gallate (EGCG): New Therapeutic Perspectives for Neuroprotection, Aging, and Neuroinflammation for the Modern Age |
| EGCG | Alzheimer's Disease | 19 | PM | 34944489 | 📋 | (-)-Epigallocatechin-3-Gallate Diminishes Intra-and Extracellular Amyloid-Induced Cytotoxic Effects on Cholinergic-like Neurons from Familial Alzheimer's Disease PSEN1 E280A |
| EGCG | Alzheimer's Disease | 18 | PM | 34612422 | 📋 | Molecular mechanisms of resveratrol and EGCG in the inhibition of Aβ 42 aggregation and disruption of Aβ 42 protofibril: similarities and differences |
| EGCG | Alzheimer's Disease | 16 | PM | 34084282 | 📋 | Epigallocatechin-3-gallate modulates Tau Post-translational modifications and cytoskeletal network |
| EGCG | Alzheimer's Disease | 15 | PM | 34012254 | 📋 | Epigallocatechin-3-Gallate Provides Protection Against Alzheimer's Disease-Induced Learning and Memory Impairments in Rats |
| EGCG | Alzheimer's Disease | 20 | PM | 33353228 | 📋 | Nutraceutical Approaches of Autophagy and Neuroinflammation in Alzheimer's Disease: A Systematic Review |
| EGCG | Alzheimer's Disease | 13 | PM | 33278382 | 📋 | Green tea extract EGCG plays a dual role in Aβ 42 protofibril disruption and membrane protection: a molecular dynamic study |
| EGCG | Alzheimer's Disease | 12 | PM | 32981185 | 📋 | The Effects of Resveratrol, Caffeine, β-Carotene, and Epigallocatechin Gallate (EGCG) on Amyloid-β 25-35 Aggregation in Synthetic Brain Membranes |
| EGCG | Alzheimer's Disease | 17 | PM | 32942205 | 📋 | The pharmacological activity of epigallocatechin-3-gallate (EGCG) on Alzheimer's disease animal model: A systematic review |
| EGCG | Alzheimer's Disease | 11 | PM | 32751722 | 📋 | Insights into the Effect of Curcumin and (-)-Epigallocatechin-3-Gallate on the Aggregation of Aβ(1-40) Monomers by Means of Molecular Dynamics |
| EGCG | Alzheimer's Disease | 9 | PM | 32441920 | 📋 | Green Tea Extracts EGCG and EGC Display Distinct Mechanisms in Disrupting Aβ 42 Protofibril |
| EGCG | Alzheimer's Disease | 8 | PM | 32326457 | 📋 | Comparative Kinetics of Acetyl- And Butyryl-Cholinesterase Inhibition by Green Tea Catechins|Relevance to the Symptomatic Treatment of Alzheimer's Disease |
| EGCG | Alzheimer's Disease | 7 | PM | 32251872 | 📋 | miR-34a-5p and miR-125b-5p Attenuate Aβ-induced Neurotoxicity Through Targeting BACE1 |
| EGCG | Alzheimer's Disease | 5 | PM | 31838720 | 📋 | Epigallocatechin-3-Gallate (EGCG) Improves Cognitive Deficits Aggravated by an Obesogenic Diet Through Modulation of Unfolded Protein Response in APPswe/PS1dE9 Mice |
| EGCG | Alzheimer's Disease | 6 | PM | 31518035 | 📋 | Mitigative Effects of Epigallocatechin Gallate in Terms of Diminishing Apoptosis and Oxidative Stress Generated by the Combination of Lead and Amyloid Peptides in Human Neuronal Cells |
| EGCG | Alzheimer's Disease | 1 | PM | 30563837 | 📋 | Combined Treatment With the Phenolics (-)-epigallocatechin-3-gallate and Ferulic Acid Improves Cognition and Reduces Alzheimer-like Pathology in Mice |
| EGCG | Alzheimer's Disease | 3 | PM | 30150930 | 📋 | EGCG Nanoparticles Attenuate Aluminum Chloride Induced Neurobehavioral Deficits, Beta Amyloid and Tau Pathology in a Rat Model of Alzheimer's Disease |
| EGCG | Alzheimer's Disease | 25 | PM | 29209211 | 📋 | Diabetes Mellitus and Alzheimer's Disease: The Protection of Epigallocatechin-3-gallate in Streptozotocin Injection-Induced Models |
| EGCG | Alzheimer's Disease | 28 | PM | 28844000 | 📋 | Epigallocatechin gallate induces extracellular degradation of amyloid β-protein by increasing neprilysin secretion from astrocytes through activation of ERK and PI3K pathways |
| EGCG | Alzheimer's Disease | 33 | PM | 28520620 | 📋 | (-)-Epigallocatechin-3-gallate ameliorates memory impairment and rescues the abnormal synaptic protein levels in the frontal cortex and hippocampus in a mouse model of Alzheimer's disease |
| EGCG | Alzheimer's Disease | 4 | PM | 26207957 | 📋 | Epigallocatechin-3-gallate Enhances Clearance of Phosphorylated Tau in Primary Neurons |
| EGCG | Alzheimer's Disease | 2 | PM | 25882496 | 📋 | (-)-Epigallocatechin-3-gallate Attenuates Cognitive Deterioration in Alzheimer's Disease Model Mice by Upregulating Neprilysin Expression |
| EGCG | Alzheimer's Disease | 29 | PM | 24356899 | 📋 | (-)-Epigallocatechin-3-gallate ameliorates learning and memory deficits by adjusting the balance of TrkA/p75NTR signaling in APP/PS1 transgenic mice |
| EGCG | Alzheimer's Disease | 26 | PM | 23807728 | 📋 | Involvement of α7 nAChR signaling cascade in epigallocatechin gallate suppression of β-amyloid-induced apoptotic cortical neuronal insults |
| EGCG | Alzheimer's Disease | 27 | PM | 23660953 | 📋 | (-)-Epigallocatechin-3-gallate alleviates spatial memory impairment in APP/PS1 mice by restoring IRS-1 signaling defects in the hippocampus |
| EGCG | Alzheimer's Disease | 14 | PM | 19622237 | 📋 | Green tea polyphenol (-)-epigallocatechin-3-gallate enhances the inhibitory effect of huperzine A on acetylcholinesterase by increasing the affinity with serum albumin |
| EGCG | Alzheimer's Disease | 10 | PM | 18695518 | 📋 | Epigallocatechin-3-gallate and Curcumin Suppress Amyloid Beta-Induced Beta-Site APP Cleaving enzyme-1 Upregulation |
| EGCG | Amyotrophic Lateral Sclerosis | 1 | PM | 33672485 | 📋 | The Impact of Microbiota on the Pathogenesis of Amyotrophic Lateral Sclerosis and the Possible Benefits of Polyphenols. An Overview |
| EGCG | Charcot-Marie-Tooth Disease | 1 | PM | 33498819 | 📋 | Metabolic and Functional Improvements in a Patient with Charcot-Marie-Tooth Disease Type 2 after EGCG Administration: A Case Report |
| EGCG | Cystic Fibrosis | 1 | PM | 27035618 | 📋 | A Novel Treatment of Cystic Fibrosis Acting On-Target: Cysteamine Plus Epigallocatechin Gallate for the Autophagy-Dependent Rescue of Class II-mutated CFTR |
| EGCG | Down Syndrome | 9 | PM | 33809669 | 📋 | Epigallocatechin-3-Gallate Plus Omega-3 Restores the Mitochondrial Complex I and F 0 F 1-ATP Synthase Activities in PBMCs of Young Children with Down Syndrome: A Pilot Study of Safety and Efficacy |
| EGCG | Down Syndrome | 8 | PM | 33633179 | 📋 | Green tea extracts containing epigallocatechin-3-gallate modulate facial development in Down syndrome |
| EGCG | Down Syndrome | 7 | PM | 32994493 | 📋 | Re-establishment of the epigenetic state and rescue of kinome deregulation in Ts65Dn mice upon treatment with green tea extract and environmental enrichment |
| EGCG | Down Syndrome | 2 | PM | 31331567 | 📋 | Usage of and Attitudes About Green Tea Extract and Epigallocathechin-3-gallate (EGCG) as a Therapy in Individuals With Down Syndrome |
| EGCG | Down Syndrome | 4 | PM | 28377597 | 📋 | Dyrk1A Overexpression Leads to Increase of 3R-tau Expression and Cognitive Deficits in Ts65Dn Down Syndrome Mice |
| EGCG | Down Syndrome | 1 | PM | 27302362 | 📋 | Safety and Efficacy of Cognitive Training Plus epigallocatechin-3-gallate in Young Adults With Down's Syndrome (TESDAD): A Double-Blind, Randomised, Placebo-Controlled, Phase 2 Trial |
| EGCG | Down Syndrome | 6 | PM | 26964795 | 📋 | The Polyphenols Resveratrol and epigallocatechin-3-gallate Restore the Severe Impairment of Mitochondria in Hippocampal Progenitor Cells From a Down Syndrome Mouse Model |
| EGCG | Down Syndrome | 5 | PM | 26748562 | 📋 | Differential Effects of Epigallocatechin-3-gallate Containing Supplements on Correcting Skeletal Defects in a Down Syndrome Mouse Model |
| EGCG | Down Syndrome | 10 | PM | 24039182 | 📋 | Epigallocatechin-3-gallate, a DYRK1A inhibitor, rescues cognitive deficits in Down syndrome mouse models and in humans |
| EGCG | Down Syndrome | 3 | PM | 23291000 | 📋 | Epigallocatechin-3-gallate Prevents Oxidative Phosphorylation Deficit and Promotes Mitochondrial Biogenesis in Human Cells From Subjects With Down's Syndrome |
| EGCG | Epidermolysis Bullosa | 1 | PM | 17139264 | 📋 | Epigallocatechin gallate's protective effect against MMP7 in recessive dystrophic epidermolysis bullosa patients |
| EGCG | Huntington's Disease | 1 | PM | 16893904 | 📋 | Green Tea (-)-Epigallocatechin-Gallate Modulates Early Events in Huntingtin Misfolding and Reduces Toxicity in Huntington's Disease Models |
| EGCG | Retinitis Pigmentosa | 2 | PM | 37822286 | 📋 | Lutein combined with EGCG improved retinitis pigmentosa against N-methyl- N nitrosourea-induced |
| EGCG | Retinitis Pigmentosa | 1 | PM | 34380903 | 📋 | Systemic epigallocatechin gallate protects against retinal degeneration and hepatic oxidative stress in the P23H-1 rat |
